iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mdo-062252

UUCD1 version

UUC-MoD-00844

Ensembl Protein ID

ENSMODP00000003114.1

UniProt Accession

F7F5W4; F7F5W4_MONDO

Protein Name

Uncharacterized protein

Gene Name

TRIM72

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000002561.4	ENSMODT00000003180.2	ENSMODP00000003114.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.70e-07	31.8	17	59

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl  f+  p++  CgH f+++Cl ++   ++ + ++ +CP C+
   Q: 17   CPLCLKLFDA-PITAECGHSFCRNCLLRL--APDPQAGTVLCPSCQ 59
           ********99.***************999..77779*********7 PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MSGAPALMQG MYQDLSCPLC LKLFDAPITA ECGHSFCRNC LLRLAPDPQA GTVLCPSCQA 60
PTKPDGLNTN QQLARLVESL AQVPQGHCEE HLDPLSVYCE QDRALICGVC ASLGKHRGHS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGAGAGGG GTGATGGCTA ATTCCAGGAG AATTCTTCAG CCTTGACAGG TGGCTCTGAT 60
ATGCGATGCC CTTCCCCCTG GTCTCTTGTT ACCACCCAAA TATAGATCTG GTTGGAATGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0042383--C:sarcolemma
GO:0001786--F:phosphatidylserine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007517--P:muscle organ development
GO:0003012--P:muscle system process
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0043569--P:negative regulation of insulin-like growth factor receptor signaling pathway
GO:0010832--P:negative regulation of myotube differentiation
GO:0001778--P:plasma membrane repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization

KEGG

mdo:100012696

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002377	Ailuropoda melanoleuca	63.84	3.00e-157	548.00
IUUC-Apl-004051	Anas platyrhynchos	30.04	1.00e-68	254.00
IUUC-Aca-004755	Anolis carolinensis	66.60	0.00e+00	653.00
IUUC-Ame-010964	Astyanax mexicanus	31.33	5.00e-80	291.00
IUUC-Bta-013476	Bos taurus	64.60	1.00e-169	589.00
IUUC-Cja-018969	Callithrix jacchus	70.31	0.00e+00	629.00
IUUC-Cfa-020155	Canis familiaris	76.20	0.00e+00	724.00
IUUC-Cpo-021646	Cavia porcellus	74.16	0.00e+00	699.00
IUUC-Csa-023855	Chlorocebus sabaeus	78.92	5.00e-147	513.00
IUUC-Dno-029142	Dasypus novemcinctus	77.04	0.00e+00	669.00
IUUC-Dor-030394	Dipodomys ordii	60.78	2.00e-79	289.00
IUUC-Ete-032801	Echinops telfairi	73.64	2.00e-56	213.00
IUUC-Eca-034378	Equus caballus	75.99	0.00e+00	716.00
IUUC-Eeu-034526	Erinaceus europaeus	73.76	0.00e+00	663.00
IUUC-Fca-036440	Felis catus	76.41	0.00e+00	732.00
IUUC-Ggo-045086	Gorilla gorilla	77.69	2.00e-163	568.00
IUUC-Hsa-046533	Homo sapiens	77.45	0.00e+00	711.00
IUUC-Itr-048959	Ictidomys tridecemlineatus	76.62	0.00e+00	732.00
IUUC-Lch-050638	Latimeria chalumnae	33.04	4.00e-79	288.00
IUUC-Loc-051971	Lepisosteus oculatus	33.95	5.00e-81	295.00
IUUC-Laf-054479	Loxodonta africana	76.20	0.00e+00	724.00
IUUC-Mcc-055814	Macaca mulatta	75.88	0.00e+00	684.00
IUUC-Meu-056767	Macropus eugenii	92.99	0.00e+00	875.00
IUUC-Mga-059415	Meleagris gallopavo	30.49	7.00e-73	268.00
IUUC-Mmr-061616	Microcebus murinus	77.24	0.00e+00	735.00
IUUC-Mmu-063094	Mus musculus	74.53	0.00e+00	699.00
IUUC-Mpu-065885	Mustela putorius furo	63.60	1.00e-161	562.00
IUUC-Mlu-068150	Myotis lucifugus	55.33	3.00e-69	254.00
IUUC-Nle-069476	Nomascus leucogenys	77.71	0.00e+00	711.00
IUUC-Opr-070871	Ochotona princeps	75.47	2.00e-117	416.00
IUUC-Oan-072738	Ornithorhynchus anatinus	85.99	0.00e+00	814.00
IUUC-Ocu-074132	Oryctolagus cuniculus	64.74	8.00e-159	553.00
IUUC-Oga-088268	Otolemur garnettii	53.97	1.00e-123	436.00
IUUC-Oar-089555	Ovis aries	60.25	2.00e-138	485.00
IUUC-Ptr-090792	Pan troglodytes	77.45	0.00e+00	711.00
IUUC-Pan-092897	Papio anubis	77.24	0.00e+00	710.00
IUUC-Psi-093742	Pelodiscus sinensis	33.83	1.00e-80	293.00
IUUC-Pab-098716	Pongo abelii	77.66	0.00e+00	712.00
IUUC-Pca-100618	Procavia capensis	66.18	1.00e-179	622.00
IUUC-Pva-102430	Pteropus vampyrus	67.43	0.00e+00	626.00
IUUC-Rno-105665	Rattus norvegicus	74.74	0.00e+00	724.00
IUUC-Sha-106854	Sarcophilus harrisii	77.87	0.00e+00	734.00
IUUC-Sar-113028	Sorex araneus	72.49	3.00e-121	427.00
IUUC-Ssc-116124	Sus scrofa	77.10	0.00e+00	709.00
IUUC-Tbe-127273	Tupaia belangeri	80.93	3.00e-113	402.00
IUUC-Ttr-128947	Tursiops truncatus	33.92	1.00e-73	270.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence