iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Oan-072738

UUCD1 version

UUC-OrA-00515

Ensembl Protein ID

ENSOANP00000002202.3

UniProt Accession

F7DDJ8; F7DDJ8_ORNAN

Protein Name

Uncharacterized protein

Gene Name

TRIM72

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOANG00000001387.3	ENSOANT00000002203.3	ENSOANP00000002202.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.00e-07	30.7	45	87
E3 activity/RING/U-box	1.20e-07	31.9	40	106

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C++Cl  f+  p++  CgH f+++Cl ++p+ +  + +   CP C+
   Q: 45   CPLCLKLFES-PVTAECGHSFCRSCLARLPQDP--QAGGTPCPSCQ 87
           ********99.999***************8888..999999****7 PP

E3 activity/RING/U-box

   S: 3    peeflCpIslelMrdPvvlpsGitydrssIekwl...asggktcPvtrqplteedlvPnltlrrliq 66
           ++e+ Cp+ l+l++ Pv++++G+++ rs++++     + gg+ cP +++p+++e l  n  l rl++
   Q: 40   YQELSCPLCLKLFESPVTAECGHSFCRSCLARLPqdpQAGGTPCPSCQAPTRPEGLSTNQQLARLVE 106
           789*****************************5588888888****************999988876 PP

Organism

Ornithorhynchus anatinus

Protein Sequence
(Fasta)

MMPRAGTRTA PWELNRFLLL GPTNRGSAMS AAPALMQGMY QELSCPLCLK LFESPVTAEC 60
GHSFCRSCLA RLPQDPQAGG TPCPSCQAPT RPEGLSTNQQ LARLVESLAQ VPQGHCEEHL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGTTTAAAAA TCAATGGGGG TGAGGCCCGG GTCGGGAAAT ACCTAGGCTT GCTGTTAGTG 60
GGAAGCAGGG GTCTCACCAG CACCCGTGGC CTTCTGCAAG GCAGCAGCCT CAGCCTGGTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003879--Butyrophylin
IPR013320--ConA-like_dom
IPR006574--PRY
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50188--B302_SPRY
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF13765--PRY
PF00622--SPRY
PF00643--zf-B_box

PRINTS

PR01407--BUTYPHLNCDUF

SMART

SM00336--BBOX
SM00589--PRY
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0030659--C:cytoplasmic vesicle membrane
GO:0042383--C:sarcolemma
GO:0001786--F:phosphatidylserine binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0007517--P:muscle organ development
GO:0003012--P:muscle system process
GO:0046627--P:negative regulation of insulin receptor signaling pathway
GO:0043569--P:negative regulation of insulin-like growth factor receptor signaling pathway
GO:0010832--P:negative regulation of myotube differentiation
GO:0001778--P:plasma membrane repair
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051260--P:protein homooligomerization

KEGG

oaa:100087382

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002377	Ailuropoda melanoleuca	64.64	4.00e-157	546.00
IUUC-Apl-004051	Anas platyrhynchos	29.98	9.00e-68	250.00
IUUC-Aca-004755	Anolis carolinensis	68.92	0.00e+00	662.00
IUUC-Ame-010964	Astyanax mexicanus	30.88	1.00e-77	283.00
IUUC-Bta-013476	Bos taurus	62.98	2.00e-173	601.00
IUUC-Cel-018370	Caenorhabditis elegans	45.24	5.00e-07	47.80
IUUC-Cja-018969	Callithrix jacchus	69.52	1.00e-177	615.00
IUUC-Cfa-020155	Canis familiaris	76.32	0.00e+00	717.00
IUUC-Cpo-021646	Cavia porcellus	75.68	0.00e+00	710.00
IUUC-Csa-023855	Chlorocebus sabaeus	78.31	1.00e-145	508.00
IUUC-Dno-029142	Dasypus novemcinctus	76.21	0.00e+00	667.00
IUUC-Dor-030394	Dipodomys ordii	62.88	2.00e-80	292.00
IUUC-Ete-032801	Echinops telfairi	75.20	3.00e-56	211.00
IUUC-Eca-034378	Equus caballus	75.69	0.00e+00	704.00
IUUC-Eeu-034526	Erinaceus europaeus	74.03	0.00e+00	670.00
IUUC-Fca-036440	Felis catus	75.90	0.00e+00	723.00
IUUC-Ggo-045086	Gorilla gorilla	77.69	2.00e-163	567.00
IUUC-Hsa-046533	Homo sapiens	77.59	0.00e+00	700.00
IUUC-Itr-048959	Ictidomys tridecemlineatus	75.26	0.00e+00	715.00
IUUC-Lch-050638	Latimeria chalumnae	32.75	2.00e-77	281.00
IUUC-Loc-051971	Lepisosteus oculatus	32.92	2.00e-77	282.00
IUUC-Laf-054479	Loxodonta africana	76.26	0.00e+00	724.00
IUUC-Mcc-055814	Macaca mulatta	75.31	0.00e+00	671.00
IUUC-Meu-056767	Macropus eugenii	83.44	0.00e+00	781.00
IUUC-Mga-059415	Meleagris gallopavo	30.06	2.00e-71	262.00
IUUC-Mmr-061616	Microcebus murinus	77.17	0.00e+00	728.00
IUUC-Mdo-062252	Monodelphis domestica	85.99	0.00e+00	814.00
IUUC-Mmu-063094	Mus musculus	73.58	0.00e+00	687.00
IUUC-Mpu-065885	Mustela putorius furo	63.56	4.00e-158	550.00
IUUC-Mlu-068150	Myotis lucifugus	75.97	3.00e-54	204.00
IUUC-Nle-069476	Nomascus leucogenys	77.43	0.00e+00	696.00
IUUC-Opr-070871	Ochotona princeps	77.33	5.00e-121	427.00
IUUC-Ocu-074132	Oryctolagus cuniculus	64.96	3.00e-160	557.00
IUUC-Olu-087666	Ostreococcus lucimarinus	35.53	9.00e-11	61.20
IUUC-Oga-088268	Otolemur garnettii	54.03	3.00e-123	434.00
IUUC-Oar-089555	Ovis aries	61.47	9.00e-139	486.00
IUUC-Ptr-090792	Pan troglodytes	77.59	0.00e+00	700.00
IUUC-Pan-092897	Papio anubis	76.68	0.00e+00	699.00
IUUC-Psi-093742	Pelodiscus sinensis	32.35	1.00e-77	283.00
IUUC-Pab-098716	Pongo abelii	77.38	0.00e+00	697.00
IUUC-Pca-100618	Procavia capensis	66.39	3.00e-178	617.00
IUUC-Pva-102430	Pteropus vampyrus	67.65	4.00e-180	623.00
IUUC-Rno-105665	Rattus norvegicus	74.00	0.00e+00	706.00
IUUC-Sha-106854	Sarcophilus harrisii	70.89	0.00e+00	665.00
IUUC-Sar-113028	Sorex araneus	74.11	5.00e-122	429.00
IUUC-Ssc-116124	Sus scrofa	77.38	0.00e+00	708.00
IUUC-Tbe-127273	Tupaia belangeri	80.09	2.00e-111	395.00
IUUC-Ttr-128947	Tursiops truncatus	34.40	1.00e-73	270.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence