iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oar-090052

Ensembl Protein ID

ENSOARP00000013662.1

UniProt Accession

W5PT81; W5PT81_SHEEP

Genbank Protein ID

ENSOARP00000013662

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AMGL01042900

Gene Name

ATXN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000012754.1	ENSOART00000013866.1	ENSOARP00000013662.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UIM	2.20e-09	36.4	226	244
UBD/Alpha-Helix/UIM	9.1e-06	16.1	246	261
UBD/Alpha-Helix/UIM	7.4e-05	13.3	346	363

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEeee 19
           +++e++q+AlalS+qE ++
   Q: 226  EDEEDFQRALALSRQEIDM 244
           69**************886 PP

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqE 16
           dE+++L++A++lS+q 
   Q: 246  DEEADLRRAIQLSMQG 261
           7*************97 PP

UBD/Alpha-Helix/UIM

   S: 1    dEdeeLqlAlalSlqEee 18
           +E+++Lq A+++Sl+ ++
   Q: 346  SEEDMLQAAVTMSLETVR 363
           7*************9875 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

MESPKFHYKQ EGSLCAQHCL NNLLQGEYFS PVELSSIAHQ LDEEERMRMA EGGVTSEDYR 60
TFLQQPSGNM DDSGFFSIQQ VISNALKVWG LELILFNSPE YQRLRIDPIN ERSFICNYKE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAATCTC CAAAAGTGAA GTTATTTTAG CTACTGAAAA TGAGGGAGGC TAAATGTTTA 60
TTGTAGAGTA ATTTTTAGTA AAATATGAGA TTTTATATAG ATGATTTTTG TTTAATATAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR033865--Ataxin-3
IPR006155--Josephin
IPR009068--S15_NS1_RNA-bd
IPR003903--UIM_dom

PROSITE

PS50957--JOSEPHIN
PS50330--UIM

Pfam

PF02099--Josephin
PF02809--UIM

SMART

SM01246--Josephin
SM00726--UIM

Gene Ontology

GO:0005759--C:mitochondrial matrix
GO:0031966--C:mitochondrial membrane
GO:0042405--C:nuclear inclusion body
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0034605--P:cellular response to heat
GO:0071218--P:cellular response to misfolded protein
GO:0035640--P:exploration behavior
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0035520--P:monoubiquitinated protein deubiquitination
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0010810--P:regulation of cell-substrate adhesion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002015	Ailuropoda melanoleuca	84.62	3.00e-176	610.00
IUUC-Atr-002735	Amborella trichopoda	48.94	3.00e-05	39.70
IUUC-Apl-003210	Anas platyrhynchos	71.73	2.00e-144	504.00
IUUC-Aca-005171	Anolis carolinensis	69.12	2.00e-126	445.00
IUUC-Aly-005625	Arabidopsis lyrata	44.05	2.00e-38	152.00
IUUC-Ath-007088	Arabidopsis thaliana	44.05	1.00e-38	152.00
IUUC-Afu-009069	Aspergillus fumigatus	33.33	2.00e-02	32.00
IUUC-Ame-010715	Astyanax mexicanus	69.77	1.00e-117	416.00
IUUC-Bta-013538	Bos taurus	96.73	0.00e+00	704.00
IUUC-Bdi-015000	Brachypodium distachyon	41.42	1.00e-33	136.00
IUUC-Bol-015894	Brassica oleracea	43.45	1.00e-38	154.00
IUUC-Bra-018020	Brassica rapa	43.71	6.00e-39	155.00
IUUC-Cel-018121	Caenorhabditis elegans	34.55	7.00e-41	160.00
IUUC-Cja-018840	Callithrix jacchus	83.10	3.00e-168	584.00
IUUC-Cfa-021035	Canis familiaris	86.89	5.00e-179	620.00
IUUC-Cpo-021776	Cavia porcellus	84.11	3.00e-171	593.00
IUUC-Csa-023257	Chlorocebus sabaeus	67.03	2.00e-133	468.00
IUUC-Cho-024878	Choloepus hoffmanni	83.43	3.00e-172	597.00
IUUC-Cgl-026754	Colletotrichum gloeosporioides	45.00	9.00e-01	29.60
IUUC-Cme-027158	Cyanidioschyzon merolae	30.05	3.00e-11	62.00
IUUC-Dre-027506	Danio rerio	66.00	5.00e-88	317.00
IUUC-Dno-029172	Dasypus novemcinctus	84.97	3.00e-179	620.00
IUUC-Dor-030900	Dipodomys ordii	94.51	4.00e-141	494.00
IUUC-Ete-033000	Echinops telfairi	56.43	2.00e-87	315.00
IUUC-Eca-034338	Equus caballus	88.15	0.00e+00	635.00
IUUC-Eeu-034585	Erinaceus europaeus	98.10	3.00e-57	214.00
IUUC-Fca-035441	Felis catus	87.23	3.00e-69	253.00
IUUC-Fal-037525	Ficedula albicollis	71.62	2.00e-134	472.00
IUUC-Gmo-039718	Gadus morhua	70.03	5.00e-107	380.00
IUUC-Gga-040774	Gallus gallus	70.98	2.00e-146	511.00
IUUC-Gac-041671	Gasterosteus aculeatus	71.53	3.00e-104	371.00
IUUC-Gma-042801	Glycine max	40.72	5.00e-35	141.00
IUUC-Ggo-044759	Gorilla gorilla	80.91	3.00e-140	491.00
IUUC-Hsa-046591	Homo sapiens	84.18	2.00e-163	568.00
IUUC-Hvu-047492	Hordeum vulgare	42.60	3.00e-32	132.00
IUUC-Itr-048851	Ictidomys tridecemlineatus	72.67	3.00e-123	434.00
IUUC-Lch-049519	Latimeria chalumnae	74.32	2.00e-107	382.00
IUUC-Lpe-050819	Leersia perrieri	42.69	2.00e-33	136.00
IUUC-Loc-051816	Lepisosteus oculatus	74.00	2.00e-125	441.00
IUUC-Laf-053784	Loxodonta africana	82.29	3.00e-175	607.00
IUUC-Mcc-055283	Macaca mulatta	87.19	4.00e-180	623.00
IUUC-Meu-056589	Macropus eugenii	73.98	1.00e-147	515.00
IUUC-Mtr-058233	Medicago truncatula	34.08	6.00e-35	140.00
IUUC-Mla-059013	Melampsora laricipopulina	38.89	3.00e-28	119.00
IUUC-Mga-059301	Meleagris gallopavo	70.98	4.00e-149	520.00
IUUC-Mmr-061038	Microcebus murinus	86.38	1.00e-180	625.00
IUUC-Mdo-062927	Monodelphis domestica	77.93	4.00e-147	513.00
IUUC-Mmu-063600	Mus musculus	77.99	1.00e-156	545.00
IUUC-Mpu-065897	Mustela putorius furo	93.06	3.00e-159	554.00
IUUC-Mlu-067543	Myotis lucifugus	92.10	2.00e-159	554.00
IUUC-Nle-069847	Nomascus leucogenys	81.15	1.00e-164	572.00
IUUC-Opr-070550	Ochotona princeps	76.86	6.00e-154	536.00
IUUC-Ont-071723	Oreochromis niloticus	68.05	6.00e-107	380.00
IUUC-Oan-073569	Ornithorhynchus anatinus	79.14	6.00e-159	553.00
IUUC-Ocu-074632	Oryctolagus cuniculus	83.24	2.00e-175	607.00
IUUC-Oba-075288	Oryza barthii	42.69	8.00e-36	144.00
IUUC-Obr-076050	Oryza brachyantha	42.11	1.00e-31	130.00
IUUC-Ogl-077174	Oryza glaberrima	42.69	8.00e-36	144.00
IUUC-Ogu-078006	Oryza glumaepatula	42.69	9.00e-36	144.00
IUUC-Oin-079278	Oryza indica	40.56	6.00e-35	141.00
IUUC-Olo-080941	Oryza longistaminata	42.69	8.00e-36	144.00
IUUC-Ome-081172	Oryza meridionalis	42.69	8.00e-36	144.00
IUUC-Oni-082239	Oryza nivara	42.69	8.00e-36	144.00
IUUC-Opu-083939	Oryza punctata	42.11	3.00e-35	142.00
IUUC-Oru-084393	Oryza rufipogon	42.69	8.00e-36	144.00
IUUC-Osa-086080	Oryza sativa	42.69	6.00e-36	144.00
IUUC-Ola-087566	Oryzias latipes	72.57	4.00e-109	387.00
IUUC-Oga-088617	Otolemur garnettii	70.62	9.00e-126	442.00
IUUC-Ptr-091435	Pan troglodytes	87.19	0.00e+00	627.00
IUUC-Pan-092742	Papio anubis	66.76	3.00e-132	464.00
IUUC-Psi-093313	Pelodiscus sinensis	89.73	3.00e-129	454.00
IUUC-Pma-094374	Petromyzon marinus	61.00	9.00e-83	300.00
IUUC-Pno-095003	Phaeosphaeria nodorum	34.52	4.60e-02	33.50
IUUC-Ppa-095601	Physcomitrella patens	44.05	2.00e-42	166.00
IUUC-Pfo-097327	Poecilia formosa	71.09	9.00e-109	386.00
IUUC-Pab-098611	Pongo abelii	85.58	2.00e-149	521.00
IUUC-Pca-101022	Procavia capensis	98.23	5.00e-64	238.00
IUUC-Ppe-101545	Prunus persica	42.86	2.00e-36	145.00
IUUC-Pva-102844	Pteropus vampyrus	86.92	2.00e-179	620.00
IUUC-Rno-104896	Rattus norvegicus	77.99	4.00e-162	563.00
IUUC-Sha-107106	Sarcophilus harrisii	80.00	2.00e-165	575.00
IUUC-Sit-110477	Setaria italica	43.27	5.00e-35	141.00
IUUC-Sly-111416	Solanum lycopersicum	39.13	4.00e-18	84.30
IUUC-Stu-112227	Solanum tuberosum	39.39	5.00e-21	94.00
IUUC-Sar-113534	Sorex araneus	77.35	5.00e-151	526.00
IUUC-Sbi-114751	Sorghum bicolor	41.53	6.00e-34	137.00
IUUC-Ssc-115274	Sus scrofa	86.92	0.00e+00	635.00
IUUC-Tgu-117426	Taeniopygia guttata	73.84	1.00e-145	508.00
IUUC-Tru-118059	Takifugu rubripes	72.86	4.00e-106	377.00
IUUC-Tsy-119448	Tarsius syrichta	82.41	3.00e-84	305.00
IUUC-Tni-120681	Tetraodon nigroviridis	88.10	8.00e-58	215.00
IUUC-Tca-121442	Theobroma cacao	36.51	1.00e-38	152.00
IUUC-Tae-123969	Triticum aestivum	41.52	2.00e-30	125.00
IUUC-Tbe-127638	Tupaia belangeri	79.95	7.00e-161	559.00
IUUC-Ttr-129288	Tursiops truncatus	80.65	1.00e-158	552.00
IUUC-Uma-129359	Ustilago maydis	37.43	3.00e-31	130.00
IUUC-Vda-129976	Verticillium dahliae	32.86	3.60e-01	31.20
IUUC-Vpa-130788	Vicugna pacos	88.15	0.00e+00	627.00
IUUC-Vvi-131227	Vitis vinifera	41.24	6.00e-34	137.00
IUUC-Xtr-132147	Xenopus tropicalis	66.31	3.00e-125	441.00
IUUC-Xma-133144	Xiphophorus maculatus	69.39	9.00e-106	376.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence