iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000060496.2	ENSRNOT00000093125.1	ENSRNOP00000076027.1
ENSRNOG00000060496.2	ENSRNOT00000086056.2	ENSRNOP00000073953.1

Annotation

Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.90e-12	46.9	325	371

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           vC +C +g+ed+  ++ C  C++++H  Cl ++  +e+p+   w CpkC 
   Q: 325  VCRICSRGDEDD-RFLLCVGCNDNYHIFCLLPP-LSEVPKGV-WRCPKCI 371
           8*********98.59******************.*******8.******5 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MKPESDDFLP PPECPVFEPS WAEFRDPLGY IAKIRPIAEK SGICKIRPPA DWQPPFAVEI 60
DNFRFTPRIQ RLNELEAQTR VKLNYLDQIA KFWEIQGSSL KIPNVERKIL DLYSLNKIVI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATCTAAAAA TGGTGGACCT GAACAGGGAG GTGAATATTT AAGGATGTGG AATTAAGCCG 60
ACTCTGAAAT TTGGAAAAAA ATAAGTTCCT GTGGGTCATC GCAGTGAGTA GGAAATTCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001606--ARID_dom
IPR003347--JmjC_dom
IPR003349--JmjN
IPR013637--Lys_sp_deMease-like_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR004198--Znf_C5HC2
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51011--ARID
PS51184--JMJC
PS51183--JMJN
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF01388--ARID
PF02373--JmjC
PF02375--JmjN
PF00628--PHD
PF08429--PLU-1
PF02928--zf-C5HC2

SMART

SM00501--BRIGHT
SM00558--JmjC
SM00545--JmjN
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0032453--F:histone demethylase activity (H3-K4 specific)
GO:0016706--F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0008270--F:zinc ion binding
GO:0060765--P:regulation of androgen receptor signaling pathway
GO:0002457--P:T cell antigen processing and presentation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001327	Ailuropoda melanoleuca	81.10	0.00e+00	2174.00
IUUC-Aca-004712	Anolis carolinensis	72.09	0.00e+00	1792.00
IUUC-Afl-008625	Aspergillus flavus	29.94	5.00e-111	396.00
IUUC-Aor-010155	Aspergillus oryzae	29.94	4.00e-111	396.00
IUUC-Bta-013099	Bos taurus	81.31	0.00e+00	2169.00
IUUC-Cja-018723	Callithrix jacchus	79.76	0.00e+00	2111.00
IUUC-Cfa-020954	Canis familiaris	80.97	0.00e+00	2165.00
IUUC-Cpo-021718	Cavia porcellus	86.56	0.00e+00	1226.00
IUUC-Csa-023682	Chlorocebus sabaeus	78.89	0.00e+00	2232.00
IUUC-Dre-028238	Danio rerio	60.55	0.00e+00	1766.00
IUUC-Dno-029435	Dasypus novemcinctus	81.38	0.00e+00	2154.00
IUUC-Dor-030226	Dipodomys ordii	75.09	0.00e+00	1516.00
IUUC-Dse-031479	Dothistroma septosporum	32.07	2.00e-107	385.00
IUUC-Eca-033834	Equus caballus	81.72	0.00e+00	2216.00
IUUC-Fca-035766	Felis catus	78.37	0.00e+00	2058.00
IUUC-Fox-037694	Fusarium oxysporum	32.24	1.00e-101	365.00
IUUC-Fso-038127	Fusarium solani	30.00	1.00e-109	392.00
IUUC-Gmo-039140	Gadus morhua	61.36	0.00e+00	1670.00
IUUC-Gac-041825	Gasterosteus aculeatus	61.88	0.00e+00	1686.00
IUUC-Ggo-045492	Gorilla gorilla	77.65	0.00e+00	2224.00
IUUC-Hsa-046399	Homo sapiens	77.40	0.00e+00	2218.00
IUUC-Itr-048348	Ictidomys tridecemlineatus	81.79	0.00e+00	2240.00
IUUC-Lch-050517	Latimeria chalumnae	69.68	0.00e+00	1947.00
IUUC-Laf-054098	Loxodonta africana	74.08	0.00e+00	1961.00
IUUC-Mcc-055740	Macaca mulatta	81.45	0.00e+00	2215.00
IUUC-Meu-056643	Macropus eugenii	73.51	0.00e+00	1996.00
IUUC-Mmr-061032	Microcebus murinus	81.59	0.00e+00	2203.00
IUUC-Mdo-062754	Monodelphis domestica	70.80	0.00e+00	1942.00
IUUC-Mmu-064016	Mus musculus	93.67	0.00e+00	2800.00
IUUC-Mpu-066800	Mustela putorius furo	80.97	0.00e+00	2169.00
IUUC-Mlu-067109	Myotis lucifugus	79.64	0.00e+00	2176.00
IUUC-Nfi-068430	Neosartorya fischeri	31.07	3.00e-110	394.00
IUUC-Nle-069569	Nomascus leucogenys	81.15	0.00e+00	2157.00
IUUC-Ont-072274	Oreochromis niloticus	62.99	0.00e+00	1744.00
IUUC-Oan-073160	Ornithorhynchus anatinus	75.44	0.00e+00	1988.00
IUUC-Ocu-074440	Oryctolagus cuniculus	81.59	0.00e+00	2188.00
IUUC-Ola-087059	Oryzias latipes	62.21	0.00e+00	1760.00
IUUC-Oga-088191	Otolemur garnettii	80.97	0.00e+00	2214.00
IUUC-Oar-090027	Ovis aries	81.31	0.00e+00	2168.00
IUUC-Ptr-091415	Pan troglodytes	79.01	0.00e+00	2248.00
IUUC-Pan-091829	Papio anubis	81.17	0.00e+00	2209.00
IUUC-Pma-094137	Petromyzon marinus	50.57	0.00e+00	1347.00
IUUC-Pfo-096645	Poecilia formosa	58.74	0.00e+00	1722.00
IUUC-Pab-097582	Pongo abelii	81.09	0.00e+00	2052.00
IUUC-Pca-100446	Procavia capensis	78.43	0.00e+00	2151.00
IUUC-Pva-102553	Pteropus vampyrus	81.11	0.00e+00	1426.00
IUUC-Pgr-103434	Puccinia graminis	35.37	7.00e-29	121.00
IUUC-Sha-106769	Sarcophilus harrisii	78.41	0.00e+00	1913.00
IUUC-Ssl-108489	Sclerotinia sclerotiorum	30.23	1.00e-113	405.00
IUUC-Sre-115161	Sporisorium reilianum	30.04	2.00e-130	461.00
IUUC-Ssc-116354	Sus scrofa	81.59	0.00e+00	2227.00
IUUC-Tru-117667	Takifugu rubripes	62.76	0.00e+00	1590.00
IUUC-Tni-119920	Tetraodon nigroviridis	62.42	0.00e+00	1695.00
IUUC-Tre-122213	Trichoderma reesei	28.64	6.00e-106	379.00
IUUC-Tvi-122263	Trichoderma virens	28.46	2.00e-101	364.00
IUUC-Tbe-128040	Tupaia belangeri	87.16	0.00e+00	971.00
IUUC-Ttr-128979	Tursiops truncatus	81.66	0.00e+00	2214.00
IUUC-Vda-129733	Verticillium dahliae	29.53	1.00e-123	438.00
IUUC-Vpa-130433	Vicugna pacos	82.28	0.00e+00	1536.00
IUUC-Xtr-132324	Xenopus tropicalis	64.55	0.00e+00	1787.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence