iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Afl-008402

Ensembl Protein ID

EED55656

UniProt Accession

B8N3M5; B8N3M5_ASPFN

Genbank Protein ID

EED55656.1

Protein Name

Ubiquitin-protein ligase (Hul4), putative

Genbank Nucleotide ID

EQ963473

Gene Name

AFLA_029280

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
AFLA_029280	EED55656	EED55656

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.00e-74	250.5	397	741

Active Site

Position(s)	Description	Evidence
710	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalqdgrlldlplsksfyklllg 102
           ++++kk l++efvgEeg+d+gG+ +e++ ll++e+++p  glf y+e+++ + + np  +    e  + F ++G+llg+a++++ +ld++l+++ +k+ll 
   Q: 397  QEEIKKGLRIEFVGEEGVDAGGLRKEWFLLLVREIFDPHHGLFIYDEDSQFC-YFNPYCF----ESSEQFFLVGVLLGLAIYNSTILDINLPPFAFKKLLA 492
           67899**************************************999976555.7799888....5678888****************************88 PP
   S: 103  k................klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegik 187
                            k++l+dl+e  p l+k l  +++  e d+ e+ ++  f ++ + +ge+ ++ L++gG++ pVtn+N++e+v+l+v+y l + ++
   Q: 493  AapqttgpqpattrstyKCNLDDLAEYRPPLAKGLRALLDF-EGDVAET-FCYDFVAQMDRYGEVVAVPLCTGGDKRPVTNANRREFVDLYVHYLLDTAVT 591
           888888888887778888*********************99.6788887.*************************************************** PP
   S: 188  eqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggyt....edspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk 283
           +q+e f++Gf +v+  + lslF++ee+ell+ G+ e +dv +l++ ++y++ ++    e  p++qwFw+++e  + + ++++L F+Tgs+r+P+ G  +l 
   Q: 592  RQFEPFKRGFFTVCGGNALSLFRPEEIELLVRGSdEPLDVASLRAVATYDN-WSdprpEMVPVVQWFWDFFEHTQPQAQRKILSFITGSDRIPAMGATSLI 691
           **********************************999************76.441111456778************************************* PP
   S: 284  prlfvirkdasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
            r+ ++ +  + +r+P++ TCfn+L L +Y++ e+l+++L  A+ +++gF+l
   Q: 692  IRVACLGD--DSSRFPTARTCFNMLGLYRYTTREQLEQRLWGAVLNSEGFGL 741
           88888877..77**************************************98 PP

Organism

Aspergillus flavus

Protein Sequence
(Fasta)

MTAGTSWVEQ WSGLKPLDVR DGDDCTRNKR WDAADMSLIE REFMESRLHL HRTLMKATEN 60
LLKRPRRPLK RPEDVRFLLM LLVNPLIYSS SQHVALHPGA TSAARSDRRP SNTKDTGHRP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGCAG GAACGTCATG GGTCGAGCAG TGGTCAGGGC TGAAGCCTCT TGACGTACGC 60
GACGGAGATG ATTGTACGAG GAATAAGAGG TGGGATGCTG CTGACATGAG CCTCATTGAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom

PROSITE

PS50237--HECT

Pfam

PF00632--HECT

SMART

SM00119--HECTc

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

afv:AFLA_029280

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001266	Ailuropoda melanoleuca	35.08	3.00e-98	350.00
IUUC-Atr-003144	Amborella trichopoda	38.23	5.00e-84	302.00
IUUC-Apl-003589	Anas platyrhynchos	34.16	2.00e-90	325.00
IUUC-Aca-004350	Anolis carolinensis	40.09	9.00e-94	336.00
IUUC-Ago-007908	Ashbya gossypii	32.88	2.00e-95	341.00
IUUC-Acl-008288	Aspergillus clavatus	79.04	0.00e+00	1217.00
IUUC-Afu-008762	Aspergillus fumigatus	78.62	0.00e+00	1221.00
IUUC-Ani-009176	Aspergillus nidulans	75.12	0.00e+00	944.00
IUUC-Ang-009791	Aspergillus niger	82.08	0.00e+00	1171.00
IUUC-Aor-009921	Aspergillus oryzae	98.35	0.00e+00	1222.00
IUUC-Ate-010295	Aspergillus terreus	80.86	0.00e+00	1197.00
IUUC-Ame-011166	Astyanax mexicanus	38.51	4.00e-84	304.00
IUUC-Bgr-011981	Blumeria graminis	58.35	0.00e+00	850.00
IUUC-Bta-012945	Bos taurus	40.53	5.00e-96	343.00
IUUC-Bci-013697	Botrytis cinerea	61.15	0.00e+00	823.00
IUUC-Cel-018150	Caenorhabditis elegans	31.47	3.00e-54	205.00
IUUC-Cja-019263	Callithrix jacchus	39.65	4.00e-93	333.00
IUUC-Cfa-020486	Canis familiaris	35.31	1.00e-99	355.00
IUUC-Cpo-021755	Cavia porcellus	35.48	2.00e-99	355.00
IUUC-Cre-022790	Chlamydomonas reinhardtii	41.00	2.00e-58	217.00
IUUC-Csa-023814	Chlorocebus sabaeus	39.56	1.00e-82	299.00
IUUC-Cho-025059	Choloepus hoffmanni	30.86	7.00e-71	260.00
IUUC-Cin-025643	Ciona intestinalis	32.13	2.00e-70	258.00
IUUC-Csv-026282	Ciona savignyi	31.00	3.00e-63	234.00
IUUC-Cgl-026526	Colletotrichum gloeosporioides	56.10	0.00e+00	787.00
IUUC-Cme-027151	Cyanidioschyzon merolae	35.70	2.00e-73	269.00
IUUC-Dre-028551	Danio rerio	41.07	8.00e-94	336.00
IUUC-Dno-029497	Dasypus novemcinctus	40.31	1.00e-95	342.00
IUUC-Dor-030756	Dipodomys ordii	40.58	5.00e-67	247.00
IUUC-Dse-031239	Dothistroma septosporum	54.09	0.00e+00	784.00
IUUC-Dme-032035	Drosophila melanogaster	35.03	5.00e-72	264.00
IUUC-Ete-032902	Echinops telfairi	32.84	2.00e-89	322.00
IUUC-Eca-033678	Equus caballus	35.31	8.00e-100	356.00
IUUC-Eeu-035109	Erinaceus europaeus	31.40	4.00e-71	261.00
IUUC-Fca-035590	Felis catus	35.81	5.00e-101	360.00
IUUC-Fal-037123	Ficedula albicollis	33.28	8.00e-83	299.00
IUUC-Fox-037941	Fusarium oxysporum	57.61	0.00e+00	815.00
IUUC-Fso-038388	Fusarium solani	56.53	0.00e+00	805.00
IUUC-Gmo-039553	Gadus morhua	39.38	2.00e-81	294.00
IUUC-Ggr-040110	Gaeumannomyces graminis	55.03	0.00e+00	766.00
IUUC-Gga-040406	Gallus gallus	34.32	1.00e-93	335.00
IUUC-Gac-042141	Gasterosteus aculeatus	34.10	2.00e-90	324.00
IUUC-Ggo-045504	Gorilla gorilla	39.43	7.00e-93	333.00
IUUC-Hsa-045786	Homo sapiens	39.43	5.00e-93	333.00
IUUC-Itr-048289	Ictidomys tridecemlineatus	31.90	2.00e-76	278.00
IUUC-Kpa-049152	Komagataella pastoris	33.07	6.00e-97	347.00
IUUC-Lch-049824	Latimeria chalumnae	40.34	1.00e-80	292.00
IUUC-Loc-052173	Lepisosteus oculatus	35.48	1.00e-101	362.00
IUUC-Laf-054017	Loxodonta africana	40.09	3.00e-95	340.00
IUUC-Mcc-055713	Macaca mulatta	39.65	3.00e-93	334.00
IUUC-Meu-056061	Macropus eugenii	32.50	3.00e-77	281.00
IUUC-Mor-057045	Magnaporthe oryzae	56.97	0.00e+00	787.00
IUUC-Mla-059187	Melampsora laricipopulina	42.28	1.00e-93	335.00
IUUC-Mga-059884	Meleagris gallopavo	40.24	9.00e-87	312.00
IUUC-Mmr-061344	Microcebus murinus	35.15	2.00e-100	358.00
IUUC-Mdo-062653	Monodelphis domestica	40.97	4.00e-96	343.00
IUUC-Mmu-063775	Mus musculus	40.66	3.00e-97	347.00
IUUC-Mpu-066069	Mustela putorius furo	35.31	1.00e-99	355.00
IUUC-Mlu-067925	Myotis lucifugus	40.31	4.00e-96	343.00
IUUC-Nfi-068439	Neosartorya fischeri	78.27	0.00e+00	1200.00
IUUC-Ncr-068903	Neurospora crassa	55.70	0.00e+00	755.00
IUUC-Nle-070046	Nomascus leucogenys	34.59	8.00e-96	342.00
IUUC-Opr-070570	Ochotona princeps	28.43	3.00e-59	221.00
IUUC-Ont-072126	Oreochromis niloticus	35.15	2.00e-97	348.00
IUUC-Oan-072933	Ornithorhynchus anatinus	39.74	2.00e-93	334.00
IUUC-Ocu-073800	Oryctolagus cuniculus	39.65	5.00e-93	333.00
IUUC-Ola-086988	Oryzias latipes	34.60	3.00e-94	337.00
IUUC-Oga-088117	Otolemur garnettii	39.65	3.00e-93	333.00
IUUC-Oar-089371	Ovis aries	40.53	7.00e-96	343.00
IUUC-Ptr-090551	Pan troglodytes	39.43	5.00e-93	333.00
IUUC-Pan-092067	Papio anubis	39.65	4.00e-93	333.00
IUUC-Psi-092963	Pelodiscus sinensis	39.87	2.00e-92	331.00
IUUC-Pma-094643	Petromyzon marinus	33.83	1.00e-80	293.00
IUUC-Ppa-095354	Physcomitrella patens	38.65	7.00e-86	310.00
IUUC-Pfo-096562	Poecilia formosa	34.98	1.00e-96	345.00
IUUC-Pab-098680	Pongo abelii	39.43	4.00e-93	333.00
IUUC-Pca-100869	Procavia capensis	32.05	2.00e-78	285.00
IUUC-Pva-103040	Pteropus vampyrus	41.16	1.00e-66	246.00
IUUC-Pgr-103315	Puccinia graminis	41.25	5.00e-99	353.00
IUUC-Ptt-103736	Puccinia triticina	41.81	1.00e-98	352.00
IUUC-Rno-105270	Rattus norvegicus	40.97	1.00e-97	348.00
IUUC-Sce-106306	Saccharomyces cerevisiae	31.67	3.00e-82	298.00
IUUC-Sha-106819	Sarcophilus harrisii	35.58	4.00e-100	357.00
IUUC-Sja-107974	Schizosaccharomyces japonicus	36.30	7.00e-62	229.00
IUUC-Spo-108271	Schizosaccharomyces pombe	36.58	6.00e-115	406.00
IUUC-Ssl-108657	Sclerotinia sclerotiorum	61.82	0.00e+00	866.00
IUUC-Smo-108858	Selaginella moellendorffii	41.33	5.00e-86	310.00
IUUC-Sar-113134	Sorex araneus	36.14	1.00e-78	286.00
IUUC-Ssc-115441	Sus scrofa	40.22	2.00e-95	341.00
IUUC-Tgu-117166	Taeniopygia guttata	34.65	3.00e-91	327.00
IUUC-Tru-118368	Takifugu rubripes	37.20	2.00e-81	295.00
IUUC-Tsy-118898	Tarsius syrichta	35.73	8.00e-76	276.00
IUUC-Tni-120143	Tetraodon nigroviridis	37.42	2.00e-81	295.00
IUUC-Tre-122108	Trichoderma reesei	57.14	0.00e+00	766.00
IUUC-Tvi-122644	Trichoderma virens	56.90	0.00e+00	786.00
IUUC-Tme-127004	Tuber melanosporum	56.64	0.00e+00	793.00
IUUC-Tbe-127292	Tupaia belangeri	32.22	1.00e-63	235.00
IUUC-Ttr-128352	Tursiops truncatus	38.11	5.00e-86	310.00
IUUC-Vda-129969	Verticillium dahliae	56.66	0.00e+00	774.00
IUUC-Vpa-130448	Vicugna pacos	33.61	4.00e-71	261.00
IUUC-Xtr-132594	Xenopus tropicalis	38.51	1.00e-82	299.00
IUUC-Xma-134157	Xiphophorus maculatus	34.70	3.00e-87	314.00
IUUC-Yli-134470	Yarrowia lipolytica	34.79	1.00e-104	372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence