iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Loc-052285

Ensembl Protein ID

ENSLOCP00000005492.1

UniProt Accession

W5MAT3; W5MAT3_LEPOC

Genbank Protein ID

ENSLOCP00000005492

Protein Name

Phosphoinositide phospholipase C

Genbank Nucleotide ID

AHAT01025256

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLOCG00000004569.1	ENSLOCT00000005500.1	ENSLOCP00000005492.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.90e-12	47.1	789	847

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekle 63
           +k +v++ly+y+aq ddeL++ k  +++ +  e+q++gW+kg  +  gk+ l fP+n+ve+++
   Q: 789  FKCTVKALYEYKAQRDDELSFSKNAIIQNV--EKQEGGWWKG--DCGGKKQLwFPSNYVEEIS 847
           6779*************************9..9*********..777777666*******986 PP

Organism

Lepisosteus oculatus

Protein Sequence
(Fasta)

TMATTTGFFS NGSVPWIEND AEVNNLYRDL ELGTVLTLYY SKKSQRPERR TFQVKLETRQ 60
IIWTRGTDKI EGEIDIREIK EIRPGRSSRD FERYIEDSSV RSDQAHCFVI LYGPEFRLKA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCACCGGTA CTAGGGATAG AGGCGCAAGA TCGACAGCAG GAAACTTCAC ATGGAAAGGA 60
AACATTTTTT TTTTTTACCA TTACACAGAC TTCTGAGCTG TAACTTAACC GTGTAACGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0727--SH2 domain
KW-0728--SH3 domain
KW-0807--Transducer

Interpro

IPR000008--C2_dom
IPR011992--EF-hand-dom_pair
IPR011993--PH_dom-like
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR016279--PLC-gamma
IPR028380--PLC-gamma1
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain

PROSITE

PS50004--C2
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3

Pfam

PF00168--C2
PF00169--PH
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN

SMART

SM00239--C2
SM00233--PH
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3

Gene Ontology

GO:0005622--C:intracellular
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0001525--P:angiogenesis
GO:0048844--P:artery morphogenesis
GO:0031101--P:fin regeneration
GO:0030851--P:granulocyte differentiation
GO:0060218--P:hematopoietic stem cell differentiation
GO:0035556--P:intracellular signal transduction
GO:0009395--P:phospholipid catabolic process
GO:0035477--P:regulation of angioblast cell migration involved in selective angioblast sprouting
GO:0008016--P:regulation of heart contraction
GO:0001570--P:vasculogenesis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001452	Ailuropoda melanoleuca	76.93	0.00e+00	2079.00
IUUC-Apl-003541	Anas platyrhynchos	69.12	0.00e+00	1791.00
IUUC-Aca-005291	Anolis carolinensis	78.48	0.00e+00	2065.00
IUUC-Ame-011004	Astyanax mexicanus	77.43	0.00e+00	2060.00
IUUC-Bta-012660	Bos taurus	77.67	0.00e+00	1977.00
IUUC-Cja-019206	Callithrix jacchus	76.93	0.00e+00	2071.00
IUUC-Cfa-020257	Canis familiaris	77.67	0.00e+00	1999.00
IUUC-Cpo-022391	Cavia porcellus	72.92	0.00e+00	1917.00
IUUC-Csa-024170	Chlorocebus sabaeus	77.10	0.00e+00	1516.00
IUUC-Cin-025520	Ciona intestinalis	47.26	0.00e+00	1118.00
IUUC-Dre-027944	Danio rerio	82.00	0.00e+00	2177.00
IUUC-Dno-029440	Dasypus novemcinctus	77.25	0.00e+00	1903.00
IUUC-Dor-031001	Dipodomys ordii	76.23	0.00e+00	2073.00
IUUC-Eca-033809	Equus caballus	77.83	0.00e+00	2001.00
IUUC-Fca-036510	Felis catus	77.59	0.00e+00	2000.00
IUUC-Fal-037541	Ficedula albicollis	78.95	0.00e+00	1896.00
IUUC-Gmo-038630	Gadus morhua	73.00	0.00e+00	1634.00
IUUC-Gga-040142	Gallus gallus	77.99	0.00e+00	2038.00
IUUC-Ggo-045063	Gorilla gorilla	76.98	0.00e+00	2090.00
IUUC-Hsa-046428	Homo sapiens	76.98	0.00e+00	2089.00
IUUC-Itr-048245	Ictidomys tridecemlineatus	77.63	0.00e+00	2056.00
IUUC-Lch-049766	Latimeria chalumnae	79.33	0.00e+00	1973.00
IUUC-Laf-053365	Loxodonta africana	77.26	0.00e+00	1982.00
IUUC-Mcc-054871	Macaca mulatta	76.92	0.00e+00	2067.00
IUUC-Meu-056724	Macropus eugenii	73.33	0.00e+00	1833.00
IUUC-Mga-059329	Meleagris gallopavo	77.19	0.00e+00	1924.00
IUUC-Mmr-061110	Microcebus murinus	76.91	0.00e+00	2081.00
IUUC-Mdo-062448	Monodelphis domestica	77.06	0.00e+00	2085.00
IUUC-Mmu-063565	Mus musculus	76.75	0.00e+00	2063.00
IUUC-Mpu-066683	Mustela putorius furo	77.14	0.00e+00	2093.00
IUUC-Mlu-067779	Myotis lucifugus	77.42	0.00e+00	1987.00
IUUC-Nle-069219	Nomascus leucogenys	78.81	0.00e+00	1757.00
IUUC-Opr-070766	Ochotona princeps	73.88	0.00e+00	1170.00
IUUC-Ont-072524	Oreochromis niloticus	84.23	0.00e+00	2253.00
IUUC-Oan-073214	Ornithorhynchus anatinus	73.33	3.00e-36	144.00
IUUC-Ocu-074361	Oryctolagus cuniculus	76.19	0.00e+00	2037.00
IUUC-Ola-086820	Oryzias latipes	81.76	0.00e+00	2242.00
IUUC-Oga-088172	Otolemur garnettii	77.29	0.00e+00	2092.00
IUUC-Oar-090306	Ovis aries	74.86	0.00e+00	1910.00
IUUC-Ptr-090682	Pan troglodytes	76.91	0.00e+00	2089.00
IUUC-Pan-092835	Papio anubis	78.92	0.00e+00	1516.00
IUUC-Psi-093344	Pelodiscus sinensis	77.32	0.00e+00	2031.00
IUUC-Pfo-096984	Poecilia formosa	80.61	0.00e+00	2151.00
IUUC-Pab-097871	Pongo abelii	77.71	0.00e+00	2065.00
IUUC-Pca-100772	Procavia capensis	71.13	0.00e+00	1892.00
IUUC-Pva-102790	Pteropus vampyrus	77.42	0.00e+00	2039.00
IUUC-Rno-105974	Rattus norvegicus	76.77	0.00e+00	2082.00
IUUC-Sar-112995	Sorex araneus	76.10	0.00e+00	2014.00
IUUC-Ssc-115360	Sus scrofa	76.98	0.00e+00	2073.00
IUUC-Tgu-116585	Taeniopygia guttata	75.04	0.00e+00	1943.00
IUUC-Tru-117742	Takifugu rubripes	83.80	0.00e+00	2300.00
IUUC-Tsy-119259	Tarsius syrichta	79.62	0.00e+00	709.00
IUUC-Tni-120833	Tetraodon nigroviridis	65.74	0.00e+00	1696.00
IUUC-Tbe-127504	Tupaia belangeri	67.74	0.00e+00	1137.00
IUUC-Xtr-132862	Xenopus tropicalis	71.97	0.00e+00	1871.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence