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Tag Content
iUUCD ID IUUC-Pan-092835
Ensembl Protein ID ENSPANP00000017732.1
UniProt Accession A0A096NXD8; A0A096NXD8_PAPAN
Genbank Protein ID ENSPANP00000017732
Protein Name Phosphoinositide phospholipase C
Genbank Nucleotide ID AHZZ01100481
Gene Name PLCG1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSPANG00000023857.1 ENSPANT00000025941.1 ENSPANP00000017732.1
Status Unreviewed
Classification
Family E-Value Score Start End
UBD/SH3 3.30e-12 46.2 418 475
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/SH3
   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGl.fPenFvekl 62
           +k  v++l+dy+aq +deLt++k  +++ +  e+q++gW++g  +  gk+ l fP+n+ve++
   Q: 418  FKCAVKALFDYKAQREDELTFTKSAIIQNV--EKQEGGWWRG--DYGGKKQLwFPSNYVEEM 475
           56789************************9..9*********..676666655******985 PP
   
Organism Papio anubis
Protein Sequence
(Fasta)
MPVIYHGHTL TTKIKFSDVL QTIKEHAFVA SEYPVILSIE DHCSIAQQRN MAQHFKKVLG 60
DTLLTKPVEI SADGLPSPNQ LKRKILIKHK KLAEGSAYEE VPTSMMYSEN DISNSIKNGI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Pan-092835|UBD,SH3|Papio anubis
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CAGATGGGAT GCCAGTTATT TACCATGGAC ACACCCTTAC CACCAAGATC AAGTTCTCAG 60
ATGTCCTGCA AACCATCAAG GAGCATGCCT TTGTGGCCTC AGAGTGAGTC AGAGGCTGGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Pan-092835|UBD,SH3|Papio anubis
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0442--Lipid degradation
KW-0443--Lipid metabolism
KW-1185--Reference proteome
KW-0728--SH3 domain
KW-0807--Transducer
Interpro

IPR000008--C2_dom
IPR001849--PH_domain
IPR001192--PI-PLC_fam
IPR028380--PLC-gamma1
IPR017946--PLC-like_Pdiesterase_TIM-brl
IPR000909--PLipase_C_PInositol-sp_X_dom
IPR001711--PLipase_C_Pinositol-sp_Y
IPR000980--SH2
IPR001452--SH3_domain
PROSITE

PS50004--C2
PS50003--PH_DOMAIN
PS50007--PIPLC_X_DOMAIN
PS50008--PIPLC_Y_DOMAIN
PS50001--SH2
PS50002--SH3
Pfam

PF00168--C2
PF00388--PI-PLC-X
PF00387--PI-PLC-Y
PF00017--SH2
PF00018--SH3_1
PRINTS

PR00390--PHPHLIPASEC
PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
SMART

SM00239--C2
SM00233--PH
SM00148--PLCXc
SM00149--PLCYc
SM00252--SH2
SM00326--SH3
Gene Ontology

GO:0005911--C:cell-cell junction
GO:0008180--C:COP9 signalosome
GO:0005829--C:cytosol
GO:0030027--C:lamellipodium
GO:0005886--C:plasma membrane
GO:0001726--C:ruffle
GO:0004435--F:phosphatidylinositol phospholipase C activity
GO:0004871--F:signal transducer activity
GO:0019722--P:calcium-mediated signaling
GO:0016477--P:cell migration
GO:0071364--P:cellular response to epidermal growth factor stimulus
GO:0007173--P:epidermal growth factor receptor signaling pathway
GO:0001701--P:in utero embryonic development
GO:0016042--P:lipid catabolic process
GO:0045766--P:positive regulation of angiogenesis
GO:0043536--P:positive regulation of blood vessel endothelial cell migration
GO:0051281--P:positive regulation of release of sequestered calcium ion into cytosol
GO:0050852--P:T cell receptor signaling pathway
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001452 Ailuropoda melanoleuca 97.16 0.00e+00 1816.00
IUUC-Apl-003541 Anas platyrhynchos 73.12 0.00e+00 1310.00
IUUC-Aca-005291 Anolis carolinensis 87.91 0.00e+00 1631.00
IUUC-Ame-011004 Astyanax mexicanus 70.26 0.00e+00 1315.00
IUUC-Bta-012660 Bos taurus 96.73 0.00e+00 1819.00
IUUC-Cja-019206 Callithrix jacchus 98.69 0.00e+00 1842.00
IUUC-Cfa-020257 Canis familiaris 97.27 0.00e+00 1819.00
IUUC-Cpo-022391 Cavia porcellus 97.71 0.00e+00 1828.00
IUUC-Csa-024170 Chlorocebus sabaeus 99.82 0.00e+00 1150.00
IUUC-Dre-027944 Danio rerio 75.78 0.00e+00 1416.00
IUUC-Dno-029440 Dasypus novemcinctus 96.62 0.00e+00 1817.00
IUUC-Dor-031001 Dipodomys ordii 95.75 0.00e+00 1795.00
IUUC-Eca-033809 Equus caballus 97.93 0.00e+00 1838.00
IUUC-Fca-036510 Felis catus 96.95 0.00e+00 1817.00
IUUC-Fal-037541 Ficedula albicollis 88.77 0.00e+00 1675.00
IUUC-Gmo-038630 Gadus morhua 79.66 0.00e+00 1216.00
IUUC-Gga-040142 Gallus gallus 88.99 0.00e+00 1656.00
IUUC-Ggo-045063 Gorilla gorilla 99.67 0.00e+00 1886.00
IUUC-Hsa-046428 Homo sapiens 99.56 0.00e+00 1884.00
IUUC-Itr-048245 Ictidomys tridecemlineatus 96.95 0.00e+00 1815.00
IUUC-Lch-049766 Latimeria chalumnae 81.28 0.00e+00 1481.00
IUUC-Loc-052285 Lepisosteus oculatus 78.92 0.00e+00 1467.00
IUUC-Laf-053365 Loxodonta africana 95.65 0.00e+00 1786.00
IUUC-Mcc-054871 Macaca mulatta 99.78 0.00e+00 1857.00
IUUC-Meu-056724 Macropus eugenii 87.49 0.00e+00 1595.00
IUUC-Mga-059329 Meleagris gallopavo 88.03 0.00e+00 1619.00
IUUC-Mmr-061110 Microcebus murinus 97.60 0.00e+00 1831.00
IUUC-Mdo-062448 Monodelphis domestica 93.89 0.00e+00 1773.00
IUUC-Mmu-063565 Mus musculus 97.11 0.00e+00 1807.00
IUUC-Mpu-066683 Mustela putorius furo 96.84 0.00e+00 1810.00
IUUC-Mlu-067779 Myotis lucifugus 97.27 0.00e+00 1820.00
IUUC-Nle-069219 Nomascus leucogenys 98.81 0.00e+00 1529.00
IUUC-Opr-070766 Ochotona princeps 93.10 0.00e+00 1444.00
IUUC-Ont-072524 Oreochromis niloticus 74.65 0.00e+00 1401.00
IUUC-Oan-073214 Ornithorhynchus anatinus 92.39 4.00e-47 179.00
IUUC-Ocu-074361 Oryctolagus cuniculus 95.75 0.00e+00 1789.00
IUUC-Ola-086820 Oryzias latipes 73.79 0.00e+00 1417.00
IUUC-Oga-088172 Otolemur garnettii 97.71 0.00e+00 1825.00
IUUC-Oar-090306 Ovis aries 95.53 0.00e+00 1795.00
IUUC-Ptr-090682 Pan troglodytes 99.56 0.00e+00 1885.00
IUUC-Psi-093344 Pelodiscus sinensis 86.70 0.00e+00 1623.00
IUUC-Pfo-096984 Poecilia formosa 73.15 0.00e+00 1374.00
IUUC-Pab-097871 Pongo abelii 99.45 0.00e+00 1882.00
IUUC-Pca-100772 Procavia capensis 89.20 0.00e+00 1642.00
IUUC-Pva-102790 Pteropus vampyrus 97.50 0.00e+00 1771.00
IUUC-Rno-105974 Rattus norvegicus 97.27 0.00e+00 1819.00
IUUC-Sar-112995 Sorex araneus 94.77 0.00e+00 1763.00
IUUC-Ssc-115360 Sus scrofa 97.16 0.00e+00 1811.00
IUUC-Tgu-116585 Taeniopygia guttata 88.33 0.00e+00 1598.00
IUUC-Tru-117742 Takifugu rubripes 74.16 0.00e+00 1409.00
IUUC-Tsy-119259 Tarsius syrichta 97.86 0.00e+00 863.00
IUUC-Tni-120833 Tetraodon nigroviridis 69.56 0.00e+00 1266.00
IUUC-Tbe-127504 Tupaia belangeri 87.48 0.00e+00 1241.00
IUUC-Ttr-128650 Tursiops truncatus 96.56 0.00e+00 1049.00
IUUC-Xtr-132862 Xenopus tropicalis 78.47 0.00e+00 1424.00
Created Date 25-Jun-2017

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