iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106816

Ensembl Protein ID

ENSSHAP00000020344.1

UniProt Accession

G3WY39; G3WY39_SARHA

Genbank Protein ID

ENSSHAP00000020344

Protein Name

Histone acetyltransferase

Genbank Nucleotide ID

AEFK01028171

Gene Name

KAT6A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000017256.1	ENSSHAT00000020505.1	ENSSHAP00000020344.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	2.30e-09	37.5	263	312

Active Site

Position(s)	Description	Evidence
680	Proton donor/acceptor	{ECO:0000256\|PIRSR:PIRSR602717-51}

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrs 53
           k C  C+++g++ ++++ C+ C++ fH +C  ++  + +p+   wiC+ Cr 
   Q: 263  KTCSSCRDQGKNADNMLFCDSCDRGFHMECCDPP-LTRMPKGM-WICQICRP 312
           68999******99*********************.9*****97.******85 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MVKLANPLYT EWILEAIKKV KKQKQRPSEE RICNAVSSSH GLDRKTVLEQ LELSVKDGTI 60
LKVSNKGLNS YKDPDNPGRI ALPKPRNLGK LDGKQNVDWN KLIKRAVEGL AESSGSTLKN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTGTAAGGTA CACATTTTTC TCATGTGAGC CTGGACATCA AAAGGAGCTG TGAGATGATC 60
TGATTTCTGT GCACCTTTTG AGGAAAACCC TGTCTCTCCA GTGCTCTTTA GGAATCTATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR002717--HAT_MYST-type
IPR005818--Histone_H1/H5_H15
IPR031280--KAT6A
IPR011991--WHTH_DNA-bd_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51504--H15
PS51726--MYST_HAT
PS50016--ZF_PHD_2

Pfam

PF01853--MOZ_SAS
PF00628--PHD

SMART

SM00526--H15
SM00249--PHD

Gene Ontology

GO:0005829--C:cytosol
GO:0070776--C:MOZ/MORF histone acetyltransferase complex
GO:0016607--C:nuclear speck
GO:0005730--C:nucleolus
GO:0000786--C:nucleosome
GO:0016605--C:PML body
GO:0003677--F:DNA binding
GO:0004402--F:histone acetyltransferase activity
GO:0003713--F:transcription coactivator activity
GO:0008270--F:zinc ion binding
GO:0090398--P:cellular senescence
GO:0043966--P:histone H3 acetylation
GO:0030099--P:myeloid cell differentiation
GO:0045892--P:negative regulation of transcription, DNA-templated
GO:0006334--P:nucleosome assembly
GO:0045893--P:positive regulation of transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001219	Ailuropoda melanoleuca	87.67	0.00e+00	2391.00
IUUC-Aca-004549	Anolis carolinensis	74.50	0.00e+00	1675.00
IUUC-Ame-010711	Astyanax mexicanus	70.73	3.00e-180	626.00
IUUC-Bta-013426	Bos taurus	87.21	0.00e+00	1905.00
IUUC-Cja-019124	Callithrix jacchus	88.96	0.00e+00	1964.00
IUUC-Cfa-021165	Canis familiaris	89.50	0.00e+00	2370.00
IUUC-Cpo-022332	Cavia porcellus	80.33	0.00e+00	1887.00
IUUC-Cne-026801	Cryptococcus neoformans	63.59	2.00e-73	271.00
IUUC-Dre-028624	Danio rerio	73.07	0.00e+00	1200.00
IUUC-Dno-029878	Dasypus novemcinctus	82.82	0.00e+00	1851.00
IUUC-Ete-032342	Echinops telfairi	89.88	0.00e+00	1749.00
IUUC-Eca-033925	Equus caballus	88.52	0.00e+00	2329.00
IUUC-Fca-035985	Felis catus	88.65	0.00e+00	2375.00
IUUC-Gmo-039182	Gadus morhua	74.50	0.00e+00	1197.00
IUUC-Gga-041028	Gallus gallus	84.28	0.00e+00	1865.00
IUUC-Gac-042131	Gasterosteus aculeatus	72.78	0.00e+00	1185.00
IUUC-Gma-044341	Glycine max	42.37	5.00e-10	60.10
IUUC-Ggo-044664	Gorilla gorilla	89.04	0.00e+00	1935.00
IUUC-Hsa-046832	Homo sapiens	89.13	0.00e+00	1939.00
IUUC-Loc-052537	Lepisosteus oculatus	76.59	0.00e+00	1242.00
IUUC-Laf-053686	Loxodonta africana	88.90	0.00e+00	2323.00
IUUC-Mcc-055429	Macaca mulatta	89.05	0.00e+00	1949.00
IUUC-Mvi-060531	Microbotryum violaceum	54.91	4.00e-72	266.00
IUUC-Mmr-061249	Microcebus murinus	86.28	0.00e+00	1923.00
IUUC-Mdo-062826	Monodelphis domestica	77.71	0.00e+00	1195.00
IUUC-Mmu-063474	Mus musculus	84.90	0.00e+00	1946.00
IUUC-Mpu-066585	Mustela putorius furo	89.32	0.00e+00	2383.00
IUUC-Mlu-066965	Myotis lucifugus	87.64	0.00e+00	2257.00
IUUC-Nle-069270	Nomascus leucogenys	88.96	0.00e+00	1936.00
IUUC-Opr-070963	Ochotona princeps	74.73	0.00e+00	1581.00
IUUC-Ont-071466	Oreochromis niloticus	71.61	0.00e+00	630.00
IUUC-Oan-073367	Ornithorhynchus anatinus	90.28	0.00e+00	2398.00
IUUC-Ocu-074100	Oryctolagus cuniculus	80.00	0.00e+00	1724.00
IUUC-Ola-087293	Oryzias latipes	73.18	0.00e+00	1192.00
IUUC-Oga-089052	Otolemur garnettii	92.44	0.00e+00	816.00
IUUC-Oar-089692	Ovis aries	85.41	0.00e+00	1821.00
IUUC-Ptr-091107	Pan troglodytes	88.96	0.00e+00	1909.00
IUUC-Pan-092524	Papio anubis	88.89	0.00e+00	1953.00
IUUC-Pfo-096641	Poecilia formosa	70.29	0.00e+00	1185.00
IUUC-Pab-098311	Pongo abelii	89.06	0.00e+00	1947.00
IUUC-Pca-100810	Procavia capensis	84.38	0.00e+00	1689.00
IUUC-Pgr-103522	Puccinia graminis	50.40	9.00e-69	255.00
IUUC-Pyt-104594	Pyrenophora triticirepentis	36.67	5.00e-46	179.00
IUUC-Rno-104990	Rattus norvegicus	85.96	0.00e+00	1880.00
IUUC-Sre-115066	Sporisorium reilianum	55.56	1.00e-77	285.00
IUUC-Tgu-116639	Taeniopygia guttata	83.44	0.00e+00	1863.00
IUUC-Tru-118571	Takifugu rubripes	73.31	0.00e+00	1217.00
IUUC-Tni-119936	Tetraodon nigroviridis	74.91	0.00e+00	1231.00
IUUC-Tbe-127928	Tupaia belangeri	95.95	0.00e+00	1576.00
IUUC-Uma-129445	Ustilago maydis	56.84	2.00e-79	290.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence