iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cpo-022507

Ensembl Protein ID

ENSCPOP00000001442.2

UniProt Accession

H0UWK5; H0UWK5_CAVPO

Genbank Protein ID

ENSCPOP00000001442

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02030364

Gene Name

DDX58

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000001598.3	ENSCPOT00000001619.2	ENSCPOP00000001442.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.10e-41	140.3	1	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 1    tdeeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL..vqkegWfrefl 73
           ++ e+r  l++ +d+vrk Ld+t +l+ y++++l+e+e++ i+a++++kg+m+aa l+L  L  +q egWfr+fl
   Q: 1    MTAEQRHNLQAYSDYVRKSLDPTHILS-YMTPWLPENEVQSIQAEKNNKGPMEAASLFLRLLleLQVEGWFRGFL 74
           5679***********************.*********************************************96 PP

Organism

Cavia porcellus

Protein Sequence
(Fasta)

MTAEQRHNLQ AYSDYVRKSL DPTHILSYMT PWLPENEVQS IQAEKNNKGP MEAASLFLRL 60
LLELQVEGWF RGFLDALNHA GYSGLYEAIE NWDFQNLEKL EDYRTLLRRL EPEFKARIIP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACGGCGG AGCAGAGGCA CAACCTGCAA GCCTACAGCG ACTATGTCCG GAAGAGTCTG 60
GACCCCACTC ACATCCTTAG CTACATGACC CCCTGGCTTC CGGAGAGTAA GTGGTGCCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0015629--C:actin cytoskeleton
GO:0005923--C:bicellular tight junction
GO:0005829--C:cytosol
GO:0032587--C:ruffle membrane
GO:0005524--F:ATP binding
GO:0003690--F:double-stranded DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0009597--P:detection of virus
GO:0045087--P:innate immune response
GO:0002230--P:positive regulation of defense response to virus by host
GO:0032725--P:positive regulation of granulocyte macrophage colony-stimulating factor production
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0032755--P:positive regulation of interleukin-6 production
GO:0032757--P:positive regulation of interleukin-8 production
GO:0042993--P:positive regulation of transcription factor import into nucleus
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0030334--P:regulation of cell migration
GO:0043330--P:response to exogenous dsRNA
GO:0039529--P:RIG-I signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001898	Ailuropoda melanoleuca	73.53	0.00e+00	1351.00
IUUC-Apl-003966	Anas platyrhynchos	52.54	0.00e+00	877.00
IUUC-Aca-004499	Anolis carolinensis	46.59	0.00e+00	766.00
IUUC-Ame-011950	Astyanax mexicanus	42.27	0.00e+00	649.00
IUUC-Bta-012489	Bos taurus	72.65	0.00e+00	1306.00
IUUC-Cel-018230	Caenorhabditis elegans	29.40	3.00e-65	243.00
IUUC-Cja-018716	Callithrix jacchus	76.72	0.00e+00	1401.00
IUUC-Cfa-020269	Canis familiaris	73.37	0.00e+00	1365.00
IUUC-Csa-024209	Chlorocebus sabaeus	76.26	0.00e+00	1419.00
IUUC-Cho-025104	Choloepus hoffmanni	70.40	0.00e+00	1095.00
IUUC-Cin-025792	Ciona intestinalis	31.85	9.00e-76	278.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	25.65	3.00e-22	101.00
IUUC-Dno-028954	Dasypus novemcinctus	73.21	0.00e+00	1309.00
IUUC-Eca-034039	Equus caballus	74.19	0.00e+00	1358.00
IUUC-Eeu-035009	Erinaceus europaeus	65.76	0.00e+00	852.00
IUUC-Fca-036169	Felis catus	73.93	0.00e+00	1385.00
IUUC-Fal-037579	Ficedula albicollis	53.00	0.00e+00	867.00
IUUC-Fso-038398	Fusarium solani	25.90	1.00e-23	105.00
IUUC-Ggo-045318	Gorilla gorilla	74.00	0.00e+00	1279.00
IUUC-Hsa-046671	Homo sapiens	77.23	0.00e+00	1409.00
IUUC-Itr-047996	Ictidomys tridecemlineatus	75.54	0.00e+00	1383.00
IUUC-Lch-050461	Latimeria chalumnae	49.03	0.00e+00	824.00
IUUC-Loc-052582	Lepisosteus oculatus	47.17	0.00e+00	793.00
IUUC-Laf-054324	Loxodonta africana	73.06	0.00e+00	1318.00
IUUC-Mcc-055390	Macaca mulatta	75.73	0.00e+00	1410.00
IUUC-Meu-056365	Macropus eugenii	53.33	4.00e-167	582.00
IUUC-Mpo-057328	Magnaporthe poae	22.97	4.30e-01	30.80
IUUC-Mmr-061407	Microcebus murinus	76.26	0.00e+00	1437.00
IUUC-Mmu-063939	Mus musculus	73.79	0.00e+00	1351.00
IUUC-Mpu-066226	Mustela putorius furo	73.65	0.00e+00	1257.00
IUUC-Mlu-068092	Myotis lucifugus	73.64	0.00e+00	1311.00
IUUC-Nfi-068405	Neosartorya fischeri	24.70	8.00e-26	113.00
IUUC-Opr-070246	Ochotona princeps	63.51	6.00e-177	614.00
IUUC-Oan-072742	Ornithorhynchus anatinus	59.60	0.00e+00	937.00
IUUC-Ocu-073959	Oryctolagus cuniculus	72.96	0.00e+00	1342.00
IUUC-Oga-089173	Otolemur garnettii	75.86	0.00e+00	1386.00
IUUC-Oar-089369	Ovis aries	72.12	0.00e+00	1281.00
IUUC-Ptr-091032	Pan troglodytes	77.23	0.00e+00	1409.00
IUUC-Pan-092383	Papio anubis	76.39	0.00e+00	1421.00
IUUC-Psi-093432	Pelodiscus sinensis	56.14	0.00e+00	1012.00
IUUC-Pma-094367	Petromyzon marinus	39.90	6.00e-110	391.00
IUUC-Pab-098416	Pongo abelii	77.19	0.00e+00	1326.00
IUUC-Pca-101006	Procavia capensis	71.93	2.00e-162	566.00
IUUC-Pva-102966	Pteropus vampyrus	74.57	0.00e+00	1360.00
IUUC-Pgr-103529	Puccinia graminis	27.02	4.00e-26	114.00
IUUC-Rno-105059	Rattus norvegicus	75.80	0.00e+00	890.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	25.69	2.00e-04	42.70
IUUC-Sar-113202	Sorex araneus	62.91	0.00e+00	922.00
IUUC-Ssc-116120	Sus scrofa	71.23	0.00e+00	1273.00
IUUC-Tgu-117314	Taeniopygia guttata	51.79	0.00e+00	888.00
IUUC-Tsy-119453	Tarsius syrichta	74.67	0.00e+00	769.00
IUUC-Ttr-128421	Tursiops truncatus	69.42	0.00e+00	1077.00
IUUC-Vpa-130602	Vicugna pacos	72.21	0.00e+00	1258.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence