iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-050037

Ensembl Protein ID

ENSLACP00000011599.1

UniProt Accession

H3APM8; H3APM8_LATCH

Genbank Protein ID

ENSLACP00000011599

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01173482

Gene Name

MDM2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000010207.1	ENSLACT00000011688.1	ENSLACP00000011599.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	57.64	1.00e-114	410.00	IUUC-Hsa-046376
E3 activity/RING/RING	49.90	5.00e-93	339.00	IUUC-Mmu-063207
E3 activity/RING/RING	51.84	9.00e-102	367.00	IUUC-Rno-105641

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

ALEYKCNINM TAETADCFNS SQITASEQEA LVKPKQLLLK LLKCAGAQKD IFTMKEVIYY 60
LGQYIMAKQL YDKNQQHIVH CSNDLLGELF GVQSFSVKEP RRLYAMISKN LLPVNQEDPI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTTTAGAAT ATAAATGCAA TATTAATATG ACAGCAGGCT GGTGGGTTAA AAATTACACT 60
GCAGTTTATG AGTGTGTTGC AGGGTATGTA TTTTTATTTT CATTATCAGC ATAGTGAACT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR028340--Mdm2
IPR015459--MDM2_E3_ligase
IPR016495--p53_neg-reg_MDM_2/4
IPR003121--SWIB_MDM2_domain
IPR001876--Znf_RanBP2
IPR001841--Znf_RING

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS50089--ZF_RING_2

Pfam

PF02201--SWIB
PF00641--zf-RanBP

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0043066--P:negative regulation of apoptotic process
GO:0071157--P:negative regulation of cell cycle arrest
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002039	Ailuropoda melanoleuca	59.92	2.00e-135	475.00
IUUC-Apl-003193	Anas platyrhynchos	59.39	4.00e-137	481.00
IUUC-Aca-004305	Anolis carolinensis	54.46	7.00e-109	387.00
IUUC-Bta-013270	Bos taurus	59.31	3.00e-133	468.00
IUUC-Cja-019744	Callithrix jacchus	59.11	7.00e-132	463.00
IUUC-Cfa-020807	Canis familiaris	57.44	8.00e-123	433.00
IUUC-Cpo-022182	Cavia porcellus	57.32	3.00e-130	458.00
IUUC-Cre-022828	Chlamydomonas reinhardtii	37.50	7.00e-06	41.60
IUUC-Csa-023541	Chlorocebus sabaeus	58.70	7.00e-131	460.00
IUUC-Cho-024831	Choloepus hoffmanni	53.48	1.00e-52	199.00
IUUC-Cin-025448	Ciona intestinalis	29.65	5.00e-20	90.90
IUUC-Csv-026151	Ciona savignyi	34.67	3.00e-12	65.10
IUUC-Dno-028950	Dasypus novemcinctus	58.42	1.00e-129	456.00
IUUC-Dor-031048	Dipodomys ordii	53.06	2.00e-56	213.00
IUUC-Ete-032264	Echinops telfairi	46.96	3.00e-101	362.00
IUUC-Eca-033301	Equus caballus	54.93	2.00e-127	448.00
IUUC-Eeu-035005	Erinaceus europaeus	56.26	7.00e-116	410.00
IUUC-Fca-035454	Felis catus	58.33	1.00e-130	459.00
IUUC-Fal-036720	Ficedula albicollis	57.24	4.00e-67	248.00
IUUC-Gmo-039296	Gadus morhua	45.14	7.00e-50	190.00
IUUC-Gga-040251	Gallus gallus	60.65	9.00e-138	483.00
IUUC-Ggo-044948	Gorilla gorilla	55.49	5.00e-120	424.00
IUUC-Hsa-046376	Homo sapiens	58.62	5.00e-131	461.00
IUUC-Itr-048328	Ictidomys tridecemlineatus	58.50	1.00e-132	466.00
IUUC-Loc-051837	Lepisosteus oculatus	58.44	6.00e-133	467.00
IUUC-Laf-053483	Loxodonta africana	55.06	1.00e-128	453.00
IUUC-Mcc-055294	Macaca mulatta	58.62	5.00e-131	460.00
IUUC-Mga-060007	Meleagris gallopavo	57.80	2.00e-122	432.00
IUUC-Mmr-060673	Microcebus murinus	58.82	3.00e-133	468.00
IUUC-Mdo-063057	Monodelphis domestica	59.80	1.00e-141	496.00
IUUC-Mmu-063207	Mus musculus	50.00	2.00e-102	365.00
IUUC-Mpu-065836	Mustela putorius furo	57.99	5.00e-135	474.00
IUUC-Mlu-068193	Myotis lucifugus	60.40	4.00e-130	457.00
IUUC-Nle-069927	Nomascus leucogenys	58.62	7.00e-131	460.00
IUUC-Opr-070590	Ochotona princeps	56.45	2.00e-123	435.00
IUUC-Ont-071984	Oreochromis niloticus	49.19	4.00e-53	201.00
IUUC-Oan-072744	Ornithorhynchus anatinus	59.41	4.00e-134	471.00
IUUC-Ocu-074071	Oryctolagus cuniculus	59.11	2.00e-130	459.00
IUUC-Ola-087329	Oryzias latipes	47.43	3.00e-57	216.00
IUUC-Oga-088135	Otolemur garnettii	55.09	2.00e-121	429.00
IUUC-Oar-090078	Ovis aries	58.99	2.00e-134	472.00
IUUC-Ptr-091399	Pan troglodytes	58.42	1.00e-130	459.00
IUUC-Pan-092720	Papio anubis	58.62	5.00e-131	460.00
IUUC-Psi-093591	Pelodiscus sinensis	58.24	8.00e-112	397.00
IUUC-Pma-094500	Petromyzon marinus	67.24	8.00e-20	90.10
IUUC-Pfo-096316	Poecilia formosa	48.09	3.00e-56	212.00
IUUC-Pab-097696	Pongo abelii	58.33	2.00e-130	459.00
IUUC-Pca-100974	Procavia capensis	54.14	3.00e-126	444.00
IUUC-Pva-102488	Pteropus vampyrus	56.05	8.00e-119	420.00
IUUC-Rno-105641	Rattus norvegicus	52.44	8.00e-108	383.00
IUUC-Sha-107314	Sarcophilus harrisii	60.04	8.00e-140	490.00
IUUC-Sar-112938	Sorex araneus	56.19	2.00e-123	436.00
IUUC-Ssc-115495	Sus scrofa	57.98	8.00e-132	463.00
IUUC-Tgu-116623	Taeniopygia guttata	59.07	5.00e-130	457.00
IUUC-Tru-117820	Takifugu rubripes	46.78	1.00e-84	306.00
IUUC-Tni-119793	Tetraodon nigroviridis	47.64	5.00e-45	175.00
IUUC-Tbe-127816	Tupaia belangeri	58.41	1.00e-68	253.00
IUUC-Ttr-129194	Tursiops truncatus	56.36	2.00e-89	322.00
IUUC-Vpa-130326	Vicugna pacos	54.79	2.00e-117	416.00
IUUC-Xtr-132216	Xenopus tropicalis	59.27	3.00e-129	454.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence