iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-067826

Ensembl Protein ID

ENSMLUP00000004195.2

UniProt Accession

G1P2U3; G1P2U3_MYOLU

Genbank Protein ID

ENSMLUP00000004195

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02053512

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000004611.2	ENSMLUT00000004610.2	ENSMLUP00000004195.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.30e-17	61.1	430	486

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ i ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 430  RVRALYDYEGQEHDELSFKAGDELTKI-EDEDEQGWCKG-RLDNGQVGLYPANYVEAIQ 486
           799************************.9**********.59*************9885 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

MSVTYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGHRLCSD LMNCLHERAR IEKAYAQQLT 60
EWARRWRQLV EKGPQYGTVE KAWMAVMSEA EKVSELHLEV KASLMNEDFE KIKNWQKEAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTCTGTCA CTTACGATGA TTCCGTTGGA GTAGAAGTGT CCAGCGACAG CTTCTGGGAG 60
GTAATGCCCA GGCTTTCCCC CCATGATACA GAAATCAGGC TGATGCCTGC CTGCCAGGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	96.09	0.00e+00	893.00
IUUC-Apl-003574	Anas platyrhynchos	88.09	0.00e+00	791.00
IUUC-Aca-004251	Anolis carolinensis	82.27	0.00e+00	766.00
IUUC-Ame-011756	Astyanax mexicanus	66.28	0.00e+00	686.00
IUUC-Bta-013193	Bos taurus	93.62	0.00e+00	844.00
IUUC-Cel-018168	Caenorhabditis elegans	30.68	2.00e-61	229.00
IUUC-Cja-018756	Callithrix jacchus	93.62	0.00e+00	845.00
IUUC-Cfa-020545	Canis familiaris	96.50	0.00e+00	926.00
IUUC-Cpo-022000	Cavia porcellus	89.51	0.00e+00	909.00
IUUC-Csa-024030	Chlorocebus sabaeus	92.36	0.00e+00	756.00
IUUC-Cin-025707	Ciona intestinalis	42.33	2.00e-106	379.00
IUUC-Csv-026244	Ciona savignyi	41.95	4.00e-53	200.00
IUUC-Dre-028104	Danio rerio	63.80	4.00e-168	584.00
IUUC-Dno-029429	Dasypus novemcinctus	93.83	0.00e+00	817.00
IUUC-Dor-030122	Dipodomys ordii	86.63	0.00e+00	786.00
IUUC-Dme-032120	Drosophila melanogaster	42.97	4.00e-108	385.00
IUUC-Eca-033367	Equus caballus	93.62	0.00e+00	863.00
IUUC-Eeu-034821	Erinaceus europaeus	78.40	0.00e+00	703.00
IUUC-Fca-036079	Felis catus	96.15	0.00e+00	888.00
IUUC-Fal-036682	Ficedula albicollis	87.87	0.00e+00	787.00
IUUC-Gmo-039681	Gadus morhua	64.83	1.00e-158	552.00
IUUC-Gga-040717	Gallus gallus	88.09	0.00e+00	789.00
IUUC-Gac-042262	Gasterosteus aculeatus	65.16	1.00e-176	612.00
IUUC-Ggo-044841	Gorilla gorilla	93.62	0.00e+00	816.00
IUUC-Hsa-046411	Homo sapiens	93.42	0.00e+00	815.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	93.21	0.00e+00	832.00
IUUC-Lch-050070	Latimeria chalumnae	66.12	0.00e+00	635.00
IUUC-Loc-051975	Lepisosteus oculatus	71.07	0.00e+00	701.00
IUUC-Laf-053839	Loxodonta africana	90.61	0.00e+00	847.00
IUUC-Mcc-055783	Macaca mulatta	93.42	0.00e+00	817.00
IUUC-Meu-056348	Macropus eugenii	65.30	3.00e-160	557.00
IUUC-Mga-060087	Meleagris gallopavo	81.91	0.00e+00	714.00
IUUC-Mmr-060827	Microcebus murinus	94.44	0.00e+00	874.00
IUUC-Mmu-064109	Mus musculus	93.42	0.00e+00	866.00
IUUC-Mpu-066591	Mustela putorius furo	96.71	0.00e+00	898.00
IUUC-Nle-069797	Nomascus leucogenys	93.83	0.00e+00	819.00
IUUC-Ont-072188	Oreochromis niloticus	62.30	4.00e-168	584.00
IUUC-Oan-073076	Ornithorhynchus anatinus	84.35	3.00e-158	551.00
IUUC-Ocu-074425	Oryctolagus cuniculus	92.80	0.00e+00	831.00
IUUC-Oba-075752	Oryza barthii	35.71	6.00e-03	38.10
IUUC-Ola-087556	Oryzias latipes	66.34	1.00e-168	586.00
IUUC-Oga-089009	Otolemur garnettii	86.25	0.00e+00	795.00
IUUC-Oar-089806	Ovis aries	94.03	0.00e+00	848.00
IUUC-Ptr-091111	Pan troglodytes	93.00	0.00e+00	810.00
IUUC-Pan-091749	Papio anubis	90.66	0.00e+00	801.00
IUUC-Psi-093704	Pelodiscus sinensis	88.30	0.00e+00	806.00
IUUC-Pfo-096680	Poecilia formosa	64.22	1.00e-172	599.00
IUUC-Pab-098584	Pongo abelii	91.48	2.00e-157	548.00
IUUC-Pca-100881	Procavia capensis	64.89	1.00e-157	549.00
IUUC-Pva-102649	Pteropus vampyrus	95.47	0.00e+00	861.00
IUUC-Rno-105431	Rattus norvegicus	93.03	0.00e+00	895.00
IUUC-Sha-106641	Sarcophilus harrisii	91.20	0.00e+00	834.00
IUUC-Sar-113461	Sorex araneus	82.30	0.00e+00	738.00
IUUC-Ssc-115349	Sus scrofa	95.67	0.00e+00	857.00
IUUC-Tgu-116876	Taeniopygia guttata	88.09	0.00e+00	788.00
IUUC-Tru-118306	Takifugu rubripes	67.74	4.00e-180	624.00
IUUC-Tsy-118901	Tarsius syrichta	83.28	5.00e-156	544.00
IUUC-Tni-120120	Tetraodon nigroviridis	67.76	0.00e+00	634.00
IUUC-Ttr-129069	Tursiops truncatus	65.25	2.00e-154	538.00
IUUC-Xtr-132925	Xenopus tropicalis	82.34	0.00e+00	772.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence