iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Psi-093920

Ensembl Protein ID

ENSPSIP00000007604.1

UniProt Accession

K7FHU4; K7FHU4_PELSI

Genbank Protein ID

ENSPSIP00000007604

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGCU01200525

Gene Name

LATS2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000006997.1	ENSPSIT00000007645.1	ENSPSIP00000007604.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/UBA	7.20e-07	29.2	102	139

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLl 39
           + ++l++lv+ G+d+e a++aL ++ + ++eaA+ey+ 
   Q: 102  NRQMLQELVNVGCDQEMAVRALKQTgSRSIEAALEYIS 139
           669*********************************86 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

MRPKTFPATT YSGNSRQRLQ EIREGLKQPS KSLGQGLPIG PGSETXXXXX XXXXXXGKDA 60
ARQQQMRPTA KFGPYQKALR EIRYSLLPFA NESGTSAITE VNRQMLQELV NVGCDQEMAV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTATAAACAG TCTACAAAAT GATTCCAGGG TTTTTCATTC TCTTTGGGAG CCATGAAGAT 60
TGTGATCTGA AGTAGGACAC TGAGTGAAAA CTGTTTAAGG ATCATCAAGA GAGGAACATT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0723--Serine/threonine-protein kinase
KW-0808--Transferase

Interpro

IPR000961--AGC-kinase_C
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR008271--Ser/Thr_kinase_AS
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS51285--AGC_KINASE_CTER
PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00108--PROTEIN_KINASE_ST
PS50030--UBA

Pfam

PF00069--Pkinase

SMART

SM00133--S_TK_X
SM00220--S_TKc

Gene Ontology

GO:0005829--C:cytosol
GO:0005815--C:microtubule organizing center
GO:0005634--C:nucleus
GO:0000922--C:spindle pole
GO:0005524--F:ATP binding
GO:0004674--F:protein serine/threonine kinase activity
GO:0034613--P:cellular protein localization
GO:0000082--P:G1/S transition of mitotic cell cycle
GO:0035329--P:hippo signaling
GO:0009755--P:hormone-mediated signaling pathway
GO:0030216--P:keratinocyte differentiation
GO:0090090--P:negative regulation of canonical Wnt signaling pathway
GO:0045736--P:negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0046620--P:regulation of organ growth

KEGG

pss:102445296

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001960	Ailuropoda melanoleuca	75.90	0.00e+00	1722.00
IUUC-Apl-003521	Anas platyrhynchos	89.23	0.00e+00	1620.00
IUUC-Aca-004995	Anolis carolinensis	80.53	0.00e+00	1815.00
IUUC-Ame-011481	Astyanax mexicanus	63.34	0.00e+00	1309.00
IUUC-Bta-012618	Bos taurus	80.35	0.00e+00	980.00
IUUC-Cel-018517	Caenorhabditis elegans	48.83	1.00e-122	434.00
IUUC-Cja-019430	Callithrix jacchus	73.13	0.00e+00	1605.00
IUUC-Cfa-020687	Canis familiaris	75.35	0.00e+00	1676.00
IUUC-Cpo-021985	Cavia porcellus	81.50	0.00e+00	1050.00
IUUC-Cho-024363	Choloepus hoffmanni	71.80	0.00e+00	640.00
IUUC-Cin-025264	Ciona intestinalis	63.69	3.00e-137	481.00
IUUC-Dre-027538	Danio rerio	63.14	0.00e+00	1321.00
IUUC-Dno-029126	Dasypus novemcinctus	77.67	0.00e+00	1758.00
IUUC-Dor-030172	Dipodomys ordii	70.84	0.00e+00	1384.00
IUUC-Dme-031656	Drosophila melanogaster	72.46	0.00e+00	629.00
IUUC-Eca-033868	Equus caballus	76.19	0.00e+00	1674.00
IUUC-Eeu-034881	Erinaceus europaeus	60.33	0.00e+00	1237.00
IUUC-Fca-036203	Felis catus	70.84	0.00e+00	1548.00
IUUC-Fal-036668	Ficedula albicollis	89.72	0.00e+00	2052.00
IUUC-Gmo-039195	Gadus morhua	84.81	0.00e+00	784.00
IUUC-Gac-041789	Gasterosteus aculeatus	61.56	0.00e+00	1211.00
IUUC-Ggo-044904	Gorilla gorilla	71.42	0.00e+00	1558.00
IUUC-Hsa-046254	Homo sapiens	73.55	0.00e+00	1571.00
IUUC-Itr-047948	Ictidomys tridecemlineatus	73.29	0.00e+00	1417.00
IUUC-Lch-050079	Latimeria chalumnae	74.43	0.00e+00	1658.00
IUUC-Loc-052265	Lepisosteus oculatus	69.03	0.00e+00	944.00
IUUC-Laf-053806	Loxodonta africana	75.18	0.00e+00	1693.00
IUUC-Mcc-055253	Macaca mulatta	73.81	0.00e+00	1595.00
IUUC-Meu-056509	Macropus eugenii	84.84	0.00e+00	822.00
IUUC-Mga-059600	Meleagris gallopavo	89.89	0.00e+00	2069.00
IUUC-Mmr-061586	Microcebus murinus	72.59	0.00e+00	1550.00
IUUC-Mdo-062126	Monodelphis domestica	81.24	0.00e+00	1821.00
IUUC-Mmu-063164	Mus musculus	69.16	0.00e+00	1459.00
IUUC-Mpu-065992	Mustela putorius furo	75.82	0.00e+00	1709.00
IUUC-Mlu-067728	Myotis lucifugus	69.20	0.00e+00	1502.00
IUUC-Nle-069546	Nomascus leucogenys	73.54	0.00e+00	1575.00
IUUC-Opr-070872	Ochotona princeps	70.67	0.00e+00	1516.00
IUUC-Ont-072296	Oreochromis niloticus	85.80	0.00e+00	925.00
IUUC-Ocu-074068	Oryctolagus cuniculus	71.68	0.00e+00	1553.00
IUUC-Ola-086756	Oryzias latipes	60.61	0.00e+00	1260.00
IUUC-Oga-089066	Otolemur garnettii	73.69	0.00e+00	1645.00
IUUC-Oar-090416	Ovis aries	79.79	0.00e+00	975.00
IUUC-Ptr-091247	Pan troglodytes	73.55	0.00e+00	1599.00
IUUC-Pan-092438	Papio anubis	73.81	0.00e+00	1594.00
IUUC-Pfo-096334	Poecilia formosa	61.47	0.00e+00	1266.00
IUUC-Pab-098452	Pongo abelii	72.99	0.00e+00	1582.00
IUUC-Pca-101081	Procavia capensis	69.93	0.00e+00	1557.00
IUUC-Ptt-103762	Puccinia triticina	38.37	2.00e-91	330.00
IUUC-Rno-105102	Rattus norvegicus	69.31	0.00e+00	1443.00
IUUC-Sha-106917	Sarcophilus harrisii	81.33	0.00e+00	1852.00
IUUC-Sar-113711	Sorex araneus	69.40	0.00e+00	1404.00
IUUC-Tgu-116553	Taeniopygia guttata	86.87	0.00e+00	1983.00
IUUC-Tru-118069	Takifugu rubripes	86.33	0.00e+00	910.00
IUUC-Tni-120617	Tetraodon nigroviridis	60.52	0.00e+00	1236.00
IUUC-Ttr-129256	Tursiops truncatus	76.52	0.00e+00	1031.00
IUUC-Xtr-132593	Xenopus tropicalis	74.34	0.00e+00	1647.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence