iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO
Protein-protein Interaction
iRefIndex	HINT	Mentha
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
dbPAF	dbPTM	UniProt
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	5.40e-13	46.8	611	669

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvk..elegkrGlfPenFvekle 63
           +v +lydy+a+  +e +++kGd++ v+  +  + gW++g    e+   rG fP+nFv+++e
   Q: 611  YVSALYDYDAAIPEEISFRKGDTIAVL--KLYEDGWWEGFVvgEDDHNRGQFPSNFVREIE 669
           799************************..9999******77889**************996 PP

Organism

Schizosaccharomyces pombe

Functional Description
(View)

Required for normal septation. Involved in the disassembly of the medial ring during septation.

Protein Sequence
(Fasta)

MSQQLSFNAS SAKPDKSFSN YFWGANDEGY HALLSRFSDV KHINEELRSF YHERANIEED 60
YAKRMAKLSR TTFSSLETGC LKESVQVMKA EVDNMAKSHL QISQLLQDDV ENAFTRYAAS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATCTATTTG ACTCACATAA ACGTTGTATT TATGTTTTTT TTAGTGTTTA TTTATTTTTT 60
CGATTAGTGT ATTTCACTAA GTAAACAAAT TATTATACGA TTTTTTATTC ACATCGAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0131--Cell cycle
KW-0132--Cell division
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0498--Mitosis
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005826--C:actomyosin contractile ring
GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005547--F:phosphatidylinositol-3,4,5-trisphosphate binding
GO:0070273--F:phosphatidylinositol-4-phosphate binding
GO:0001786--F:phosphatidylserine binding
GO:1903475--P:mitotic actomyosin contractile ring assembly
GO:0007067--P:mitotic nuclear division

KEGG

spo:SPBC11C11.02

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001807	Ailuropoda melanoleuca	26.45	2.00e-23	101.00
IUUC-Apl-003258	Anas platyrhynchos	25.37	9.00e-26	108.00
IUUC-Aca-005344	Anolis carolinensis	25.35	8.00e-28	115.00
IUUC-Ath-006771	Arabidopsis thaliana	25.64	2.00e-01	26.90
IUUC-Acl-008110	Aspergillus clavatus	38.87	7.00e-71	260.00
IUUC-Afl-008516	Aspergillus flavus	38.54	1.00e-70	259.00
IUUC-Afu-008763	Aspergillus fumigatus	36.89	7.00e-73	266.00
IUUC-Ani-009231	Aspergillus nidulans	38.54	3.00e-62	231.00
IUUC-Ang-009578	Aspergillus niger	38.87	5.00e-65	241.00
IUUC-Aor-010112	Aspergillus oryzae	38.54	3.00e-70	257.00
IUUC-Ate-010371	Aspergillus terreus	39.87	4.00e-67	247.00
IUUC-Bta-013548	Bos taurus	26.62	1.00e-27	115.00
IUUC-Bci-013913	Botrytis cinerea	39.07	4.00e-69	254.00
IUUC-Cja-019037	Callithrix jacchus	26.98	2.00e-23	101.00
IUUC-Cpo-022393	Cavia porcellus	23.93	5.00e-15	73.60
IUUC-Cre-022856	Chlamydomonas reinhardtii	40.00	1.70e+00	28.10
IUUC-Csa-023180	Chlorocebus sabaeus	26.12	6.00e-28	116.00
IUUC-Cho-024736	Choloepus hoffmanni	30.71	1.00e-09	56.20
IUUC-Csv-026227	Ciona savignyi	25.00	4.00e-16	76.60
IUUC-Dre-028698	Danio rerio	25.84	6.00e-32	129.00
IUUC-Dno-028886	Dasypus novemcinctus	25.77	6.00e-27	112.00
IUUC-Dse-031165	Dothistroma septosporum	47.69	1.00e-10	60.50
IUUC-Ete-032236	Echinops telfairi	31.50	3.00e-10	58.50
IUUC-Eca-033950	Equus caballus	26.80	4.00e-29	120.00
IUUC-Fca-035870	Felis catus	26.74	3.00e-26	110.00
IUUC-Fal-037102	Ficedula albicollis	24.72	4.00e-23	100.00
IUUC-Ggr-039791	Gaeumannomyces graminis	39.15	3.00e-68	251.00
IUUC-Gga-040188	Gallus gallus	23.78	2.00e-24	105.00
IUUC-Gac-041508	Gasterosteus aculeatus	24.91	1.00e-29	122.00
IUUC-Ggo-044750	Gorilla gorilla	26.80	4.00e-29	120.00
IUUC-Hsa-046755	Homo sapiens	26.80	2.00e-29	120.00
IUUC-Itr-048941	Ictidomys tridecemlineatus	26.12	3.00e-27	114.00
IUUC-Loc-052618	Lepisosteus oculatus	27.92	6.00e-30	123.00
IUUC-Laf-054116	Loxodonta africana	26.57	3.00e-25	107.00
IUUC-Mcc-055757	Macaca mulatta	26.12	4.00e-28	117.00
IUUC-Mpo-057500	Magnaporthe poae	39.50	4.00e-68	251.00
IUUC-Mga-059524	Meleagris gallopavo	24.26	4.00e-25	107.00
IUUC-Mvi-060493	Microbotryum violaceum	30.77	5.00e-39	154.00
IUUC-Mmr-060735	Microcebus murinus	26.13	2.00e-26	111.00
IUUC-Mdo-062497	Monodelphis domestica	26.42	1.00e-18	85.50
IUUC-Mmu-063381	Mus musculus	25.61	4.00e-24	103.00
IUUC-Mpu-066686	Mustela putorius furo	26.12	1.00e-27	115.00
IUUC-Mlu-067462	Myotis lucifugus	25.99	1.00e-27	115.00
IUUC-Nfi-068483	Neosartorya fischeri	36.89	9.00e-73	266.00
IUUC-Ncr-068751	Neurospora crassa	40.93	2.00e-69	255.00
IUUC-Nle-069072	Nomascus leucogenys	25.77	6.00e-27	113.00
IUUC-Opr-070779	Ochotona princeps	40.91	3.00e-15	74.30
IUUC-Ont-072107	Oreochromis niloticus	27.52	6.00e-29	119.00
IUUC-Ola-087254	Oryzias latipes	25.35	1.00e-29	122.00
IUUC-Oga-088229	Otolemur garnettii	25.64	8.00e-26	109.00
IUUC-Oar-089195	Ovis aries	26.01	9.00e-25	105.00
IUUC-Pan-091699	Papio anubis	26.46	3.00e-28	117.00
IUUC-Psi-093831	Pelodiscus sinensis	26.39	2.00e-29	121.00
IUUC-Pno-094940	Phaeosphaeria nodorum	38.72	1.00e-69	255.00
IUUC-Pfo-096443	Poecilia formosa	26.81	6.00e-24	103.00
IUUC-Pab-098656	Pongo abelii	26.48	4.00e-26	110.00
IUUC-Pva-103137	Pteropus vampyrus	25.60	2.00e-25	107.00
IUUC-Pte-104127	Pyrenophora teres	40.21	1.00e-68	253.00
IUUC-Pyt-104705	Pyrenophora triticirepentis	39.86	5.00e-71	261.00
IUUC-Rno-105299	Rattus norvegicus	25.09	3.00e-25	107.00
IUUC-Sja-107975	Schizosaccharomyces japonicus	44.57	8.00e-156	541.00
IUUC-Sre-115063	Sporisorium reilianum	39.80	6.00e-66	244.00
IUUC-Ssc-116422	Sus scrofa	25.76	1.00e-27	115.00
IUUC-Tgu-116919	Taeniopygia guttata	25.00	8.00e-26	109.00
IUUC-Tru-118122	Takifugu rubripes	25.87	4.00e-27	113.00
IUUC-Tni-120177	Tetraodon nigroviridis	25.87	7.00e-29	119.00
IUUC-Tur-126265	Triticum urartu	22.14	9.30e-01	27.30
IUUC-Tme-126946	Tuber melanosporum	37.14	6.00e-68	250.00
IUUC-Ttr-128642	Tursiops truncatus	25.60	5.00e-26	109.00
IUUC-Uma-129545	Ustilago maydis	39.46	3.00e-65	241.00
IUUC-Vda-129797	Verticillium dahliae	40.42	3.00e-71	261.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence