iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Xtr-132455

Ensembl Protein ID

ENSXETP00000024426.3

UniProt Accession

F6YTM2; F6YTM2_XENTR

Genbank Protein ID

ENSXETP00000024426

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AAMC01041766

Gene Name

kmt2d

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSXETG00000011176.3	ENSXETT00000024426.3	ENSXETP00000024426.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.30e-25	89.5	165	214

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkCrsk 54
           kvC  C+++ged+ ++++C+ C++ +H  Clk++  e+lp+++ w C+ Cr +
   Q: 165  KVCQTCRQPGEDT-MMLVCDACDKGYHTFCLKPA-IECLPTDS-WKCKTCRVC 214
           58*********76.9*******************.9******8.******965 PP

Organism

Xenopus tropicalis

Protein Sequence
(Fasta)

TLIGFAEGVS STQLFEPTGH CWAHHWCASW SAGVIHVEGT GLINVDKAVY SGISQKCEYC 60
NRMGATIQCH STGCLRRYHF PCAAASGSFQ SMKTLKLLCT EHLGEAIAMV FLFTLDDSRC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTCTAATTG GCTTTGCAGA GGGTGTGTCA TCTACACAAC TTTTTGAACC TACAGGTAAA 60
AAATCAGTTT ATAAAGTGCT CATGAAATAT ATATAGGTCT TTGTGTGAAA TCTGAGTATA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0005634--C:nucleus
GO:0008168--F:methyltransferase activity
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001806	Ailuropoda melanoleuca	86.17	0.00e+00	1025.00
IUUC-Apl-003311	Anas platyrhynchos	52.68	0.00e+00	898.00
IUUC-Aca-005364	Anolis carolinensis	46.62	0.00e+00	1363.00
IUUC-Ame-010612	Astyanax mexicanus	79.49	0.00e+00	976.00
IUUC-Bta-013011	Bos taurus	62.53	0.00e+00	1298.00
IUUC-Cel-018354	Caenorhabditis elegans	34.32	1.00e-57	219.00
IUUC-Cja-019841	Callithrix jacchus	86.73	0.00e+00	1031.00
IUUC-Cfa-021131	Canis familiaris	86.55	0.00e+00	1031.00
IUUC-Cpo-021957	Cavia porcellus	63.01	0.00e+00	1284.00
IUUC-Csa-023722	Chlorocebus sabaeus	86.90	0.00e+00	1032.00
IUUC-Cho-024469	Choloepus hoffmanni	60.22	4.00e-95	345.00
IUUC-Cme-027224	Cyanidioschyzon merolae	35.63	3.00e-10	60.80
IUUC-Dre-028110	Danio rerio	50.38	0.00e+00	845.00
IUUC-Dno-029932	Dasypus novemcinctus	86.37	0.00e+00	1029.00
IUUC-Dor-030569	Dipodomys ordii	53.25	0.00e+00	810.00
IUUC-Dme-031590	Drosophila melanogaster	36.93	1.00e-59	225.00
IUUC-Ete-032572	Echinops telfairi	88.36	0.00e+00	869.00
IUUC-Eca-033945	Equus caballus	40.37	9.00e-168	585.00
IUUC-Eeu-034848	Erinaceus europaeus	62.94	4.00e-154	541.00
IUUC-Fca-035424	Felis catus	86.73	0.00e+00	1033.00
IUUC-Fal-037179	Ficedula albicollis	88.31	0.00e+00	1051.00
IUUC-Gmo-038719	Gadus morhua	81.18	0.00e+00	868.00
IUUC-Gga-040815	Gallus gallus	42.61	0.00e+00	779.00
IUUC-Gac-042436	Gasterosteus aculeatus	78.39	0.00e+00	937.00
IUUC-Ggo-044711	Gorilla gorilla	86.73	0.00e+00	1031.00
IUUC-Hsa-046567	Homo sapiens	86.73	0.00e+00	1032.00
IUUC-Itr-048510	Ictidomys tridecemlineatus	86.55	0.00e+00	1031.00
IUUC-Lch-050086	Latimeria chalumnae	51.18	0.00e+00	922.00
IUUC-Loc-051979	Lepisosteus oculatus	82.10	0.00e+00	1012.00
IUUC-Laf-054377	Loxodonta africana	64.28	0.00e+00	1324.00
IUUC-Mcc-055577	Macaca mulatta	80.71	0.00e+00	935.00
IUUC-Meu-055992	Macropus eugenii	88.18	0.00e+00	985.00
IUUC-Mga-059541	Meleagris gallopavo	49.07	0.00e+00	732.00
IUUC-Mmr-061772	Microcebus murinus	86.73	0.00e+00	1030.00
IUUC-Mdo-062876	Monodelphis domestica	64.06	2.00e-150	527.00
IUUC-Mmu-063903	Mus musculus	86.15	0.00e+00	1019.00
IUUC-Mpu-066700	Mustela putorius furo	86.73	0.00e+00	1030.00
IUUC-Mlu-068180	Myotis lucifugus	62.21	0.00e+00	1256.00
IUUC-Nle-069232	Nomascus leucogenys	52.66	0.00e+00	945.00
IUUC-Opr-070304	Ochotona princeps	75.58	0.00e+00	830.00
IUUC-Ont-071881	Oreochromis niloticus	59.75	0.00e+00	1193.00
IUUC-Oan-072945	Ornithorhynchus anatinus	51.89	0.00e+00	931.00
IUUC-Ocu-074053	Oryctolagus cuniculus	86.73	0.00e+00	1029.00
IUUC-Ola-086384	Oryzias latipes	78.94	0.00e+00	954.00
IUUC-Oga-088450	Otolemur garnettii	85.86	0.00e+00	1046.00
IUUC-Oar-089975	Ovis aries	62.00	0.00e+00	1295.00
IUUC-Ptr-091073	Pan troglodytes	84.97	0.00e+00	900.00
IUUC-Pan-092871	Papio anubis	86.90	0.00e+00	1034.00
IUUC-Pma-094252	Petromyzon marinus	46.30	2.00e-95	344.00
IUUC-Pfo-097525	Poecilia formosa	57.49	0.00e+00	1153.00
IUUC-Pab-097679	Pongo abelii	86.73	0.00e+00	1031.00
IUUC-Pca-100499	Procavia capensis	86.37	0.00e+00	1030.00
IUUC-Pva-102898	Pteropus vampyrus	86.02	0.00e+00	1016.00
IUUC-Rno-105660	Rattus norvegicus	84.67	0.00e+00	957.00
IUUC-Sha-107431	Sarcophilus harrisii	87.57	0.00e+00	990.00
IUUC-Sar-113183	Sorex araneus	72.86	1.00e-92	336.00
IUUC-Ssc-115678	Sus scrofa	86.45	0.00e+00	1023.00
IUUC-Tgu-116677	Taeniopygia guttata	52.53	0.00e+00	897.00
IUUC-Tru-117922	Takifugu rubripes	78.94	0.00e+00	955.00
IUUC-Tsy-118932	Tarsius syrichta	51.99	0.00e+00	950.00
IUUC-Tni-119970	Tetraodon nigroviridis	55.50	0.00e+00	695.00
IUUC-Tbe-127625	Tupaia belangeri	77.51	2.00e-113	405.00
IUUC-Ttr-129162	Tursiops truncatus	85.34	0.00e+00	1043.00
IUUC-Vpa-130236	Vicugna pacos	42.52	2.00e-98	355.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence