iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ame-010757

Ensembl Protein ID

ENSAMXP00000018353.1

UniProt Accession

W5LEU1; W5LEU1_ASTMX

Genbank Protein ID

ENSAMXP00000018353

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

APWO01034432

Gene Name

USP15

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSAMXG00000017820.1	ENSAMXT00000018353.1	ENSAMXP00000018353.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.40e-118	396.2	169	813
ULD/UDP/UBQ/UBQ_Other	1.90e-07	31.1	26	96

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+ QcLsnip+l+e++l+ k++ +lne+np ++kge++k++++l+++lw++k ++v+pr ++++++++a++fsgy+
   Q: 169  CGLSNLGNTCFMNSATQCLSNIPPLTEYFLKdKYQDELNEDNPLGMKGEIAKAYAELIKQLWSGKYSYVTPRPFKTQVGRFAPQFSGYQ 257
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD++E+laflld+l+e+l++ ++kp+ +++++d   ++d+     a+e++ k+n+s+i+d+F+g +ks+++c+ c ++s++++pf++l
   Q: 258  QQDSHELLAFLLDGLHEDLNRIRKKPYIQLKDAD--GRPDKvvaeeAWENHIKRNDSIIVDIFHGLFKSTLVCPVCSKISVTFDPFCYL 344
           ******************************9999..5555555777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p+k+e+ +e                                                                            
   Q: 345  TLPLPMKKERTLEvylvrldplakptqykltvpkvgyisdlcaslsvlsgvaaekmivtdiynhrfhrifatnenlssimerddiyvfe 433
           *********9999**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 434  vavnrledtdhvvipvhlrekykqsgynhtstplfgqpflitvprtlseekfynllllrlcrfvrsaleeeesdethsskqhaingnat 522
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 523  ngileegspsemetdeqddessqdqelpsendnsqsedsvggdndlengvgpenstkgqqqvtghkkrlftfqfnnmgktdlsfikeep 611
           ***************************************************************************************** PP
   S: 186  .......................................................slqdcLesftkeeelegenkyycekckkkqeaek 219
                                                                  +l+dc+e ft++e+l  e+ +yc++ck++q+a+k
   Q: 612  rqirfdeghlrlsdrsylsldwepeikkkyfdesvaedfdkhesmeyklqkkaffKLKDCIELFTTKEKLGAEDPWYCPSCKQHQQATK 700
           ***************************************************************************************** PP
   S: 220  klklkklPevLilhLkRfsfseeqksrekinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.W 306
           kl+l++lP+vL++hLkRfs+s+  ++r k+++ v+fpl+ Ld+s+f+++p+ +   +++Y+Liav +H+G++++GHY+ay+kn++++ W
   Q: 701  KLDLWSLPPVLVVHLKRFSYSR--YMRDKLDSLVDFPLHdLDMSEFLINPNAG---PCRYDLIAVSNHYGGMGGGHYTAYAKNKDDGkW 784
           ******************9977..6999*********************9988...8**************************65555* PP
   S: 307  llfdDskVtevkeeevleetgstaYvlfYkrr 338
           ++fdDs V++v+e+++++   + aYvlfY+r+
   Q: 785  YNFDDSIVSPVSEDQIVS---KAAYVLFYQRQ 813
           ******************...*********96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 12   eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk.....GkiL.eddktLadyglkdgstihllekksg 75
           + t++++++dt+ ++ ++++k+++ip + + rL++k      ++L ++d t++d gl++g+++++++k+++
   Q: 26   VVTRRFSKADTIDTIEKEMRKLFSIPdEMETRLWNKymtntFEPLnKPDSTIQDAGLYQGQVLVIEQKNED 96
           78999*********************666*****996664433469*********************9986 PP

Organism

Astyanax mexicanus

Protein Sequence
(Fasta)

MFVKHCKVEV YLTELKLCED SNMDNVVTRR FSKADTIDTI EKEMRKLFSI PDEMETRLWN 60
KYMTNTFEPL NKPDSTIQDA GLYQGQVLVI EQKNEDGTWP RGSSTPKSSG ASNLSALPKI 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATGCTATAA TTGGTTTACC TAATTGTAAC CATTCCTATC CCTGGTTTAT CTCAGGTACT 60
TAATAGACAG TCACTGGTTC AAGCAGTGGA AGAAATATGT GGGCTTTGAC AGCTGGGACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR029071--Ubiquitin-rel_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF14836--Ubiquitin_3
PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000058	Aegilops tauschii	38.64	3.00e-121	429.00
IUUC-Aml-001852	Ailuropoda melanoleuca	79.98	0.00e+00	1330.00
IUUC-Atr-002991	Amborella trichopoda	37.09	3.00e-125	442.00
IUUC-Apl-003249	Anas platyrhynchos	79.36	0.00e+00	1293.00
IUUC-Aca-004261	Anolis carolinensis	77.83	0.00e+00	1263.00
IUUC-Aly-005644	Arabidopsis lyrata	37.73	2.00e-125	443.00
IUUC-Ath-006782	Arabidopsis thaliana	37.26	9.00e-126	444.00
IUUC-Acl-008284	Aspergillus clavatus	43.97	5.00e-54	207.00
IUUC-Afl-008507	Aspergillus flavus	37.01	7.00e-58	219.00
IUUC-Afu-008878	Aspergillus fumigatus	34.75	8.00e-60	226.00
IUUC-Ani-009479	Aspergillus nidulans	43.42	4.00e-53	204.00
IUUC-Ang-009562	Aspergillus niger	38.20	6.00e-57	216.00
IUUC-Aor-009949	Aspergillus oryzae	36.76	8.00e-57	216.00
IUUC-Bta-013128	Bos taurus	77.80	0.00e+00	1308.00
IUUC-Bdi-014013	Brachypodium distachyon	37.41	3.00e-137	483.00
IUUC-Cel-018203	Caenorhabditis elegans	55.08	1.00e-72	268.00
IUUC-Cja-019222	Callithrix jacchus	78.84	0.00e+00	1331.00
IUUC-Cfa-020035	Canis familiaris	79.98	0.00e+00	1330.00
IUUC-Cpo-022071	Cavia porcellus	79.58	0.00e+00	1278.00
IUUC-Csa-023882	Chlorocebus sabaeus	79.86	0.00e+00	1328.00
IUUC-Cin-025292	Ciona intestinalis	45.90	0.00e+00	654.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	34.84	2.00e-63	238.00
IUUC-Cne-026852	Cryptococcus neoformans	41.79	1.00e-71	265.00
IUUC-Cme-027338	Cyanidioschyzon merolae	54.19	9.00e-67	248.00
IUUC-Dno-029025	Dasypus novemcinctus	76.96	0.00e+00	1288.00
IUUC-Dor-030956	Dipodomys ordii	80.20	0.00e+00	943.00
IUUC-Dse-031432	Dothistroma septosporum	41.30	2.00e-59	225.00
IUUC-Eca-034340	Equus caballus	79.86	0.00e+00	1326.00
IUUC-Eeu-034488	Erinaceus europaeus	75.65	0.00e+00	907.00
IUUC-Fca-035552	Felis catus	77.56	0.00e+00	1299.00
IUUC-Fal-036618	Ficedula albicollis	79.24	0.00e+00	1287.00
IUUC-Fso-038291	Fusarium solani	39.06	3.00e-64	241.00
IUUC-Gmo-038680	Gadus morhua	64.84	0.00e+00	677.00
IUUC-Ggr-039740	Gaeumannomyces graminis	41.94	7.00e-62	233.00
IUUC-Gga-041146	Gallus gallus	78.76	0.00e+00	1283.00
IUUC-Gac-041679	Gasterosteus aculeatus	89.40	0.00e+00	1441.00
IUUC-Gma-043077	Glycine max	42.42	4.00e-138	485.00
IUUC-Ggo-045002	Gorilla gorilla	79.98	0.00e+00	1328.00
IUUC-Hsa-046052	Homo sapiens	79.98	0.00e+00	1330.00
IUUC-Hvu-047108	Hordeum vulgare	39.70	3.00e-124	439.00
IUUC-Itr-048306	Ictidomys tridecemlineatus	77.74	0.00e+00	1302.00
IUUC-Lch-050107	Latimeria chalumnae	79.08	0.00e+00	1395.00
IUUC-Loc-052105	Lepisosteus oculatus	86.26	0.00e+00	1388.00
IUUC-Lma-052981	Leptosphaeria maculans	36.70	2.00e-66	248.00
IUUC-Laf-053645	Loxodonta africana	80.10	0.00e+00	1328.00
IUUC-Mcc-055586	Macaca mulatta	79.98	0.00e+00	1330.00
IUUC-Meu-056764	Macropus eugenii	71.15	0.00e+00	795.00
IUUC-Mor-056985	Magnaporthe oryzae	40.34	6.00e-62	233.00
IUUC-Mtr-058138	Medicago truncatula	38.16	4.00e-140	492.00
IUUC-Mga-060162	Meleagris gallopavo	78.88	0.00e+00	1285.00
IUUC-Mvi-060324	Microbotryum violaceum	42.39	4.00e-72	266.00
IUUC-Mmr-061105	Microcebus murinus	79.86	0.00e+00	1325.00
IUUC-Mdo-062107	Monodelphis domestica	78.90	0.00e+00	1316.00
IUUC-Mmu-063662	Mus musculus	79.25	0.00e+00	1318.00
IUUC-Mpu-065868	Mustela putorius furo	78.09	0.00e+00	1318.00
IUUC-Mlu-068000	Myotis lucifugus	74.26	0.00e+00	1229.00
IUUC-Nfi-068330	Neosartorya fischeri	34.14	6.00e-60	226.00
IUUC-Nle-069874	Nomascus leucogenys	79.86	0.00e+00	1328.00
IUUC-Opr-071212	Ochotona princeps	79.65	0.00e+00	1262.00
IUUC-Ont-071834	Oreochromis niloticus	91.67	0.00e+00	1444.00
IUUC-Ocu-074573	Oryctolagus cuniculus	80.10	0.00e+00	1331.00
IUUC-Oba-075553	Oryza barthii	40.51	3.00e-128	452.00
IUUC-Obr-076410	Oryza brachyantha	39.97	1.00e-126	447.00
IUUC-Ogl-077583	Oryza glaberrima	40.51	3.00e-128	452.00
IUUC-Ogu-077990	Oryza glumaepatula	39.94	1.00e-122	434.00
IUUC-Oin-079300	Oryza indica	40.66	3.00e-129	456.00
IUUC-Olo-080387	Oryza longistaminata	39.94	4.00e-119	422.00
IUUC-Ome-081963	Oryza meridionalis	39.73	4.00e-120	426.00
IUUC-Oni-082303	Oryza nivara	40.24	1.00e-123	437.00
IUUC-Opu-083770	Oryza punctata	39.97	2.00e-126	446.00
IUUC-Oru-085141	Oryza rufipogon	40.31	3.00e-125	443.00
IUUC-Osa-085641	Oryza sativa	40.66	3.00e-129	456.00
IUUC-Olu-087717	Ostreococcus lucimarinus	39.85	3.00e-125	442.00
IUUC-Oga-089022	Otolemur garnettii	78.29	0.00e+00	1314.00
IUUC-Oar-089767	Ovis aries	79.61	0.00e+00	1326.00
IUUC-Ptr-091319	Pan troglodytes	78.05	0.00e+00	1312.00
IUUC-Pan-091968	Papio anubis	79.86	0.00e+00	1328.00
IUUC-Psi-093849	Pelodiscus sinensis	79.26	0.00e+00	1285.00
IUUC-Pma-094533	Petromyzon marinus	58.75	0.00e+00	922.00
IUUC-Pno-094890	Phaeosphaeria nodorum	36.12	4.00e-59	224.00
IUUC-Pfo-097110	Poecilia formosa	89.89	0.00e+00	1438.00
IUUC-Pab-098664	Pongo abelii	79.86	0.00e+00	1328.00
IUUC-Pca-100359	Procavia capensis	63.26	0.00e+00	917.00
IUUC-Ppe-101587	Prunus persica	38.54	2.00e-139	490.00
IUUC-Pva-102394	Pteropus vampyrus	77.93	0.00e+00	1283.00
IUUC-Pte-104102	Pyrenophora teres	35.60	3.00e-57	218.00
IUUC-Pyt-104812	Pyrenophora triticirepentis	38.75	6.00e-57	217.00
IUUC-Rno-105383	Rattus norvegicus	77.80	0.00e+00	1304.00
IUUC-Sce-106170	Saccharomyces cerevisiae	37.53	1.00e-60	229.00
IUUC-Sha-107393	Sarcophilus harrisii	78.78	0.00e+00	1316.00
IUUC-Spo-108291	Schizosaccharomyces pombe	44.03	1.00e-73	271.00
IUUC-Smo-108686	Selaginella moellendorffii	48.35	2.00e-80	293.00
IUUC-Sit-109930	Setaria italica	41.40	2.00e-131	463.00
IUUC-Sar-113498	Sorex araneus	79.86	0.00e+00	1325.00
IUUC-Sbi-114549	Sorghum bicolor	40.28	6.00e-127	448.00
IUUC-Sre-115130	Sporisorium reilianum	48.71	2.00e-75	278.00
IUUC-Ssc-115285	Sus scrofa	79.86	0.00e+00	1327.00
IUUC-Tgu-116529	Taeniopygia guttata	79.24	0.00e+00	1293.00
IUUC-Tru-118298	Takifugu rubripes	90.28	0.00e+00	1473.00
IUUC-Tsy-119117	Tarsius syrichta	68.73	0.00e+00	1081.00
IUUC-Tni-120093	Tetraodon nigroviridis	87.07	0.00e+00	1414.00
IUUC-Tca-121670	Theobroma cacao	39.47	3.00e-119	422.00
IUUC-Tre-121888	Trichoderma reesei	41.43	2.00e-62	234.00
IUUC-Tae-123874	Triticum aestivum	40.42	4.00e-125	442.00
IUUC-Tur-126478	Triticum urartu	39.70	1.00e-121	431.00
IUUC-Tbe-127672	Tupaia belangeri	78.45	0.00e+00	919.00
IUUC-Vda-129781	Verticillium dahliae	36.54	1.00e-66	249.00
IUUC-Vpa-130469	Vicugna pacos	79.86	0.00e+00	1327.00
IUUC-Vvi-131454	Vitis vinifera	40.94	5.00e-127	448.00
IUUC-Xtr-132729	Xenopus tropicalis	73.28	0.00e+00	1226.00
IUUC-Xma-133550	Xiphophorus maculatus	89.65	0.00e+00	1430.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence