iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Fca-035490

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02199041

Gene Name

KLHL1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000004830.3	ENSFCAT00000004831.3	ENSFCAP00000004464.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB	6.80e-19	68.0	56	123
E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box	5.00e-07	29.0	155	181

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_3-box: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgkldene 69
           +Dvil+vg+++++ah++vL++ S++F a+f+++  e k ++++++++++p ++ +l++F Ytg l+++e
   Q: 56   CDVILIVGNRKIPAHRLVLSSVSDYFAAMFTSDVCEAK-QEEIKMEGIDPNALWDLVQFAYTGCLELKE 123
           9************************************9.**************************9986 PP

E3 adaptor/Cullin RING/BCR/BTB_3-box: 3-box

   S: 1    leNclgilrfAdlydcpdLkdaaldfi 27
           ++Nclgi++fAd+ +c +L+++a++++
   Q: 155  PSNCLGIRAFADAQGCIELMKVAHSYT 181
           89***********************95 PP

Organism

Felis catus

Protein Sequence
(Fasta)

TPSFLYVTCR LSATSHSLTP QSDMDSSSSE EFYQAVHHAE QTFRKMESYL KQQQLCDVIL 60
IVGNRKIPAH RLVLSSVSDY FAAMFTSDVC EAKQEEIKME GIDPNALWDL VQFAYTGCLE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACACCATCTT TTTTGTATGT GACTTGCAGG TTGTCAGCAA CTAGCCATTC ACTGACACCT 60
CAAAGTGATA TGGACTCCAG TAGCTCTGAA GAATTCTATC AGGCCGTTCA CCATGCTGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0880--Kelch repeat
KW-1185--Reference proteome
KW-0677--Repeat

Interpro

IPR011705--BACK
IPR017096--BTB-kelch_protein
IPR000210--BTB/POZ_dom
IPR015916--Gal_Oxidase_b-propeller
IPR015915--Kelch-typ_b-propeller
IPR006652--Kelch_1
IPR011333--SKP1/BTB/POZ

PROSITE

PS50097--BTB

Pfam

PF07707--BACK
PF00651--BTB
PF01344--Kelch_1

SMART

SM00875--BACK
SM00225--BTB
SM00612--Kelch

Gene Ontology

GO:0031463--C:Cul3-RING ubiquitin ligase complex
GO:0005737--C:cytoplasm
GO:0030425--C:dendrite
GO:0043025--C:neuronal cell body
GO:0007628--P:adult walking behavior
GO:0021680--P:cerebellar Purkinje cell layer development
GO:0016358--P:dendrite development
GO:0016567--P:protein ubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001478	Ailuropoda melanoleuca	99.49	0.00e+00	1140.00
IUUC-Apl-003408	Anas platyrhynchos	96.40	0.00e+00	1108.00
IUUC-Aca-004384	Anolis carolinensis	95.21	0.00e+00	1103.00
IUUC-Bta-012684	Bos taurus	98.97	0.00e+00	1133.00
IUUC-Bci-013875	Botrytis cinerea	28.24	1.00e-18	87.00
IUUC-Cja-019103	Callithrix jacchus	98.63	0.00e+00	1133.00
IUUC-Cfa-020670	Canis familiaris	99.49	0.00e+00	1139.00
IUUC-Cpo-021951	Cavia porcellus	98.97	0.00e+00	1135.00
IUUC-Csa-023607	Chlorocebus sabaeus	98.45	0.00e+00	1130.00
IUUC-Dno-029854	Dasypus novemcinctus	98.80	0.00e+00	1134.00
IUUC-Dor-030497	Dipodomys ordii	78.01	0.00e+00	843.00
IUUC-Ete-033156	Echinops telfairi	72.35	4.00e-143	501.00
IUUC-Eca-033525	Equus caballus	99.49	0.00e+00	1140.00
IUUC-Fal-037099	Ficedula albicollis	97.50	0.00e+00	1101.00
IUUC-Gmo-039532	Gadus morhua	77.82	0.00e+00	870.00
IUUC-Gga-041081	Gallus gallus	96.74	0.00e+00	1114.00
IUUC-Gac-041582	Gasterosteus aculeatus	78.00	0.00e+00	896.00
IUUC-Ggo-044717	Gorilla gorilla	98.80	0.00e+00	1133.00
IUUC-Hsa-045726	Homo sapiens	98.80	0.00e+00	1133.00
IUUC-Itr-048921	Ictidomys tridecemlineatus	98.97	0.00e+00	1137.00
IUUC-Lch-050265	Latimeria chalumnae	77.12	0.00e+00	912.00
IUUC-Loc-052321	Lepisosteus oculatus	86.11	0.00e+00	994.00
IUUC-Laf-054378	Loxodonta africana	98.80	0.00e+00	1130.00
IUUC-Mcc-054985	Macaca mulatta	98.80	0.00e+00	1132.00
IUUC-Mga-059582	Meleagris gallopavo	77.53	0.00e+00	910.00
IUUC-Mmr-061255	Microcebus murinus	98.85	0.00e+00	1034.00
IUUC-Mdo-062369	Monodelphis domestica	98.63	0.00e+00	1130.00
IUUC-Mmu-063334	Mus musculus	98.11	0.00e+00	1129.00
IUUC-Nle-069856	Nomascus leucogenys	98.80	0.00e+00	1134.00
IUUC-Ont-071932	Oreochromis niloticus	79.14	0.00e+00	913.00
IUUC-Ocu-074469	Oryctolagus cuniculus	98.80	0.00e+00	1134.00
IUUC-Oin-080100	Oryza indica	29.62	4.00e-33	136.00
IUUC-Ola-087436	Oryzias latipes	78.79	0.00e+00	902.00
IUUC-Olu-087696	Ostreococcus lucimarinus	36.78	1.00e-33	136.00
IUUC-Oga-088528	Otolemur garnettii	98.46	0.00e+00	1129.00
IUUC-Oar-089603	Ovis aries	98.80	0.00e+00	1129.00
IUUC-Ptr-090657	Pan troglodytes	98.28	0.00e+00	1129.00
IUUC-Psi-092962	Pelodiscus sinensis	95.90	0.00e+00	1108.00
IUUC-Pfo-096954	Poecilia formosa	78.25	0.00e+00	905.00
IUUC-Pab-097812	Pongo abelii	98.28	0.00e+00	1107.00
IUUC-Pva-103042	Pteropus vampyrus	99.14	0.00e+00	1137.00
IUUC-Sbi-114612	Sorghum bicolor	29.24	7.00e-34	139.00
IUUC-Ssc-115880	Sus scrofa	99.14	0.00e+00	1134.00
IUUC-Tgu-116624	Taeniopygia guttata	94.59	0.00e+00	974.00
IUUC-Tru-117780	Takifugu rubripes	77.35	0.00e+00	879.00
IUUC-Tsy-119339	Tarsius syrichta	89.52	0.00e+00	994.00
IUUC-Tni-120794	Tetraodon nigroviridis	76.37	0.00e+00	858.00
IUUC-Tbe-127398	Tupaia belangeri	99.69	0.00e+00	675.00
IUUC-Ttr-129024	Tursiops truncatus	98.97	0.00e+00	1138.00
IUUC-Vpa-130515	Vicugna pacos	99.31	0.00e+00	1135.00
IUUC-Vvi-131673	Vitis vinifera	33.74	3.00e-41	163.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence