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Tag Content
UUCD2 ID IUUC-Dre-028464
UUCD1 version UUC-DaR-00044
Ensembl Protein ID ENSDARP00000084255.4
UniProt Accession A1A5X2; FBXL7_DANRE
Genbank Protein ID AAI28846.1; AAI29208.1
Protein Name F-box/LRR-repeat protein 7; F-box and leucine-rich repeat protein 7
Genbank Nucleotide ID CR450710; BC129207
Gene Name fbxl7; zgc:158346
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSDARG00000062251.4 ENSDART00000089822.4 ENSDARP00000084255.4
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/SCF/F-box 1.70e-06 29.1 112 155
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/SCF/F-box
   S: 103  ldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
           +d lp++  ++i+++l++++l+r+arvcrrw++la +++lw+t+
   Q: 112  VDILPDHAFLQIFTHLPTNQLCRCARVCRRWYNLAWDPRLWRTI 155
           577999**************************99999****997 PP
   
Organism Danio rerio
Functional Description
(View)

Functional Description


     Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
 Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Protein Sequence
(Fasta)
MGANNGKQSG SEGKGSSSIS SDLSSSTDQT STKAPKNAAT SEDSDLSMRT VSTPSPALIL 60
PPRSSSAVLN GSSTSSSTFG TETIAMVHMP PTSLTHPQRC LRQPRDQQGA PVDILPDHAF 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Dre-028464|E3,F-box|Danio rerio
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CCAGTCTCTC CTTCTGGAGG ACTACGCGCT GTCTGGAGAC GAAGAGCTTC TAACATGAAG 60
AAAATGCATA ACCGACACTT TATCTGAAGT AATTCAGCTT TTAAACAGCC ATTTGCGGAG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Dre-028464|E3,F-box|Danio rerio
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0433--Leucine-rich repeat
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp
PROSITE

PS50181--FBOX
Pfam

PF12937--F-box-like
PF13516--LRR_6
SMART

SM00256--FBOX
SM00367--LRR_CC
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005815--C:microtubule organizing center
GO:0016567--P:protein ubiquitination
KEGG dre:569430
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002298 Ailuropoda melanoleuca 81.33 0.00e+00 739.00
IUUC-Apl-003410 Anas platyrhynchos 81.29 0.00e+00 748.00
IUUC-Aca-004422 Anolis carolinensis 79.31 0.00e+00 760.00
IUUC-Ath-007540 Arabidopsis thaliana 27.01 6.00e-22 99.40
IUUC-Ago-007947 Ashbya gossypii 26.11 3.00e-21 97.80
IUUC-Ame-010878 Astyanax mexicanus 90.22 0.00e+00 799.00
IUUC-Bta-013145 Bos taurus 81.11 0.00e+00 739.00
IUUC-Cja-019612 Callithrix jacchus 80.89 0.00e+00 734.00
IUUC-Cfa-020920 Canis familiaris 77.73 0.00e+00 701.00
IUUC-Cpo-022293 Cavia porcellus 81.82 0.00e+00 743.00
IUUC-Csa-024100 Chlorocebus sabaeus 81.57 0.00e+00 732.00
IUUC-Dno-028849 Dasypus novemcinctus 80.49 0.00e+00 729.00
IUUC-Dor-030835 Dipodomys ordii 82.32 3.00e-85 308.00
IUUC-Dme-031686 Drosophila melanogaster 49.34 4.00e-106 379.00
IUUC-Eca-034259 Equus caballus 80.69 0.00e+00 761.00
IUUC-Fca-035850 Felis catus 80.72 0.00e+00 728.00
IUUC-Fal-037009 Ficedula albicollis 82.48 0.00e+00 785.00
IUUC-Gmo-038560 Gadus morhua 77.48 2.00e-105 375.00
IUUC-Gga-040391 Gallus gallus 80.89 0.00e+00 742.00
IUUC-Gac-041464 Gasterosteus aculeatus 74.34 0.00e+00 655.00
IUUC-Ggo-044556 Gorilla gorilla 82.00 0.00e+00 743.00
IUUC-Hsa-046685 Homo sapiens 82.11 0.00e+00 776.00
IUUC-Itr-048013 Ictidomys tridecemlineatus 81.74 0.00e+00 772.00
IUUC-Lch-050268 Latimeria chalumnae 79.60 0.00e+00 734.00
IUUC-Loc-051910 Lepisosteus oculatus 82.72 0.00e+00 800.00
IUUC-Laf-053599 Loxodonta africana 81.33 0.00e+00 745.00
IUUC-Mcc-055225 Macaca mulatta 82.11 0.00e+00 776.00
IUUC-Meu-056341 Macropus eugenii 80.47 0.00e+00 763.00
IUUC-Mga-059525 Meleagris gallopavo 80.67 0.00e+00 736.00
IUUC-Mmr-060571 Microcebus murinus 81.91 0.00e+00 775.00
IUUC-Mdo-062229 Monodelphis domestica 81.33 0.00e+00 743.00
IUUC-Mmu-063408 Mus musculus 81.95 0.00e+00 779.00
IUUC-Mpu-065742 Mustela putorius furo 81.10 0.00e+00 768.00
IUUC-Mlu-067442 Myotis lucifugus 79.18 0.00e+00 739.00
IUUC-Nle-069404 Nomascus leucogenys 81.33 0.00e+00 763.00
IUUC-Opr-070457 Ochotona princeps 80.73 0.00e+00 759.00
IUUC-Ont-072288 Oreochromis niloticus 72.84 0.00e+00 683.00
IUUC-Oan-073492 Ornithorhynchus anatinus 81.12 0.00e+00 726.00
IUUC-Ocu-074513 Oryctolagus cuniculus 80.94 0.00e+00 728.00
IUUC-Ola-086573 Oryzias latipes 72.84 0.00e+00 650.00
IUUC-Olu-087656 Ostreococcus lucimarinus 25.00 7.00e-07 48.10
IUUC-Oga-088674 Otolemur garnettii 80.90 0.00e+00 755.00
IUUC-Oar-090268 Ovis aries 77.90 0.00e+00 715.00
IUUC-Ptr-091375 Pan troglodytes 82.11 0.00e+00 776.00
IUUC-Pan-091683 Papio anubis 81.78 0.00e+00 742.00
IUUC-Psi-093199 Pelodiscus sinensis 80.89 0.00e+00 743.00
IUUC-Pfo-097004 Poecilia formosa 72.41 0.00e+00 682.00
IUUC-Pab-098590 Pongo abelii 81.57 0.00e+00 733.00
IUUC-Pca-100228 Procavia capensis 84.74 0.00e+00 688.00
IUUC-Pva-103166 Pteropus vampyrus 80.69 0.00e+00 756.00
IUUC-Rno-104887 Rattus norvegicus 81.84 0.00e+00 737.00
IUUC-Sha-107379 Sarcophilus harrisii 78.54 0.00e+00 739.00
IUUC-Spo-108376 Schizosaccharomyces pombe 23.47 1.00e-16 81.60
IUUC-Sly-111591 Solanum lycopersicum 34.04 4.00e-30 126.00
IUUC-Stu-112488 Solanum tuberosum 33.83 3.00e-30 126.00
IUUC-Sar-113379 Sorex araneus 80.04 0.00e+00 755.00
IUUC-Ssc-115408 Sus scrofa 81.33 0.00e+00 741.00
IUUC-Tgu-117432 Taeniopygia guttata 80.22 0.00e+00 761.00
IUUC-Tru-117799 Takifugu rubripes 73.24 0.00e+00 679.00
IUUC-Tsy-119149 Tarsius syrichta 83.50 4.00e-47 182.00
IUUC-Tni-120688 Tetraodon nigroviridis 72.84 0.00e+00 676.00
IUUC-Tbe-127372 Tupaia belangeri 80.90 0.00e+00 756.00
IUUC-Ttr-128176 Tursiops truncatus 80.51 0.00e+00 757.00
IUUC-Vpa-130343 Vicugna pacos 86.89 5.00e-129 454.00
IUUC-Xtr-132187 Xenopus tropicalis 78.76 0.00e+00 733.00
Created Date 25-Jun-2017

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