iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.10e-11	43.6	3	60

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaq.nddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekl 62
            +v+++yd++++  + eL++  Gdv+ v    +  egW++g k+++g+ GlfP+ +ve +
   Q: 3    SYVRAMYDFTGEpGSSELSIATGDVLSVT-RSDVGEGWWEG-KNARGQIGLFPAAYVEVM 60
           589*******985799************8.***********.7**************976 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MTSYVRAMYD FTGEPGSSEL SIATGDVLSV TRSDVGEGWW EGKNARGQIG LFPAAYVEVM 60
SAAEAQKLSA SGATSVPQVP DPFASPPLPR YDQTADDDGS NWDDEDDWSD DNDTYSEIGP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTCAGTTTA ATTCCGTAAT CCAAGAAACG GTAACACTTC ACACTTGGTG ATTCAGAATT 60
AGTAGATATT TCTTGTCTGT TTATGGCCCC TGTGAAGACA GGACTCGAAT TAGCGTAAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR027267--AH/BAR-dom
IPR001683--Phox
IPR001452--SH3_domain
IPR014536--Snx9_subfam
IPR019497--Sorting_nexin_WASP-bd-dom

PROSITE

PS50195--PX
PS50002--SH3

Pfam

PF10456--BAR_3_WASP_bdg
PF00787--PX
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00312--PX
SM00326--SH3

Gene Ontology

GO:0005938--C:cell cortex
GO:0031410--C:cytoplasmic vesicle
GO:0043025--C:neuronal cell body
GO:0048471--C:perinuclear region of cytoplasm
GO:0005886--C:plasma membrane
GO:0042734--C:presynaptic membrane
GO:0071212--C:subsynaptic reticulum
GO:0043195--C:terminal bouton
GO:0005546--F:phosphatidylinositol-4,5-bisphosphate binding
GO:0000045--P:autophagosome assembly
GO:0071456--P:cellular response to hypoxia
GO:0030032--P:lamellipodium assembly
GO:0007067--P:mitotic nuclear division
GO:0001956--P:positive regulation of neurotransmitter secretion
GO:1990709--P:presynaptic active zone organization
GO:0015031--P:protein transport

KEGG

dme:Dmel_CG6757

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001493	Ailuropoda melanoleuca	37.28	4.00e-70	258.00
IUUC-Apl-003889	Anas platyrhynchos	36.71	2.00e-70	259.00
IUUC-Ame-011163	Astyanax mexicanus	38.04	6.00e-69	254.00
IUUC-Bta-013027	Bos taurus	37.47	2.00e-71	263.00
IUUC-Cel-018605	Caenorhabditis elegans	39.74	3.00e-72	265.00
IUUC-Cja-019428	Callithrix jacchus	38.30	6.00e-73	267.00
IUUC-Cfa-021208	Canis familiaris	38.04	1.00e-71	263.00
IUUC-Cpo-021353	Cavia porcellus	37.78	1.00e-71	263.00
IUUC-Cho-025020	Choloepus hoffmanni	33.21	5.00e-41	161.00
IUUC-Cin-025695	Ciona intestinalis	33.25	9.00e-70	256.00
IUUC-Csv-025870	Ciona savignyi	29.49	5.00e-73	268.00
IUUC-Cne-026820	Cryptococcus neoformans	44.07	5.00e-08	52.80
IUUC-Dre-027983	Danio rerio	38.04	3.00e-69	255.00
IUUC-Fca-036506	Felis catus	37.78	5.00e-71	261.00
IUUC-Fal-037443	Ficedula albicollis	36.46	7.00e-70	257.00
IUUC-Gmo-039464	Gadus morhua	33.05	4.00e-57	214.00
IUUC-Gac-041835	Gasterosteus aculeatus	35.31	7.00e-63	234.00
IUUC-Ggo-045438	Gorilla gorilla	36.39	3.00e-64	238.00
IUUC-Hsa-046762	Homo sapiens	38.30	3.00e-73	268.00
IUUC-Itr-048294	Ictidomys tridecemlineatus	36.96	6.00e-71	261.00
IUUC-Lch-050438	Latimeria chalumnae	33.16	6.00e-87	314.00
IUUC-Loc-052748	Lepisosteus oculatus	36.41	1.00e-71	263.00
IUUC-Laf-053373	Loxodonta africana	37.85	4.00e-71	261.00
IUUC-Mcc-054953	Macaca mulatta	38.05	2.00e-72	265.00
IUUC-Mla-058814	Melampsora laricipopulina	45.45	2.00e-08	54.30
IUUC-Mga-059536	Meleagris gallopavo	36.46	2.00e-70	259.00
IUUC-Mmr-061000	Microcebus murinus	38.11	2.00e-72	265.00
IUUC-Mdo-061885	Monodelphis domestica	37.28	3.00e-69	255.00
IUUC-Mmu-063532	Mus musculus	37.53	4.00e-70	258.00
IUUC-Mlu-067314	Myotis lucifugus	31.90	2.00e-84	305.00
IUUC-Ont-072028	Oreochromis niloticus	37.54	2.00e-67	249.00
IUUC-Oan-073741	Ornithorhynchus anatinus	54.39	3.00e-16	77.00
IUUC-Ola-086919	Oryzias latipes	44.44	8.00e-12	64.70
IUUC-Oga-088465	Otolemur garnettii	37.53	2.00e-72	265.00
IUUC-Oar-089562	Ovis aries	37.78	1.00e-71	263.00
IUUC-Ptr-090632	Pan troglodytes	38.30	3.00e-73	268.00
IUUC-Pan-092192	Papio anubis	38.05	2.00e-72	265.00
IUUC-Psi-093346	Pelodiscus sinensis	32.11	2.00e-83	302.00
IUUC-Pma-094619	Petromyzon marinus	34.19	3.00e-79	288.00
IUUC-Pfo-096634	Poecilia formosa	37.85	3.00e-71	262.00
IUUC-Pab-097866	Pongo abelii	38.30	4.00e-73	268.00
IUUC-Pva-102273	Pteropus vampyrus	37.22	9.00e-72	263.00
IUUC-Rno-105513	Rattus norvegicus	31.09	5.00e-81	294.00
IUUC-Ssc-116184	Sus scrofa	36.16	2.00e-73	269.00
IUUC-Tgu-117370	Taeniopygia guttata	33.00	1.00e-83	303.00
IUUC-Tru-117764	Takifugu rubripes	32.31	8.00e-83	300.00
IUUC-Tni-119947	Tetraodon nigroviridis	36.39	6.00e-70	257.00
IUUC-Ttr-128700	Tursiops truncatus	35.05	1.00e-64	239.00
IUUC-Xtr-132466	Xenopus tropicalis	33.61	4.00e-56	211.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence