iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Sha-107331

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01073005

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000011139.1	ENSSHAT00000013131.1	ENSSHAP00000013025.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.10e-113	380.2	707	1072

Active Site

Position(s)	Description	Evidence
1040	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 707  QNAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 791
           67899*******************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + di++lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 792  EGIVVDVPFASFFLSQLLGHhhsifYSSVDELPSLDAEFYKNLTSIKRY-DGDISDLGLTLSY--DEDVMGQLVCHELVPGGKTIPV 875
           ********************777777999********************.7799998777776..5999****************** PP
   S: 166  tneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFwe 251
           tneNk +Y++l++++r++++ik+q++a+ +Gf+++i+ e++++F++ el+ li+G+ +eid+edlkk+t y gg++ ++++i+w+w+
   Q: 876  TNENKISYIHLMAHFRMHTQIKNQTAALISGFRSIIKSEWIRMFSTPELQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVIIWLWD 962
           ********************************************************9****************************** PP
   S: 252  vl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPeY 313
           +l ++f+ +er++fL+FvT++sr Pl Gfa+lk                        + +f+irk++   rlP+s+TCfn+LkLP+Y
   Q: 963  ILaNDFTPDERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKKEPGGRLPTSSTCFNLLKLPNY 1049
           **99*************************************************************9999****************** PP
   S: 314  sskeilkekLlyAieetkgFels 336
           s+k+il+ekL+yAi++++gFels
   Q: 1050 SKKSILREKLRYAISMNTGFELS 1072
           ********************985 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

MFSTSQSSRA QFLDKARQAR EERRGQKEKE RAAVQIQALV RRFLCRCRLQ RDIRKEIDEF 60
FDSIDPTGAN KRSALSLFKI ARKLLFIFRA REDELRFGML CRCILSSMEA ENEPKVWYVS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGTTCAGCA CATCCCAGTC ATCCCGAGCC CAGTTCCTGG ACAAAGCCCG TCAGGCCAGG 60
GAAGAGAGGC GGGGACAGAA GGAGAAGGAG CGGGCTGCGG TGCAGATACA GGCCCTGGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS
IPR027401--Myosin-like_IQ_dom

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

KEGG

shr:100926111

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	39.08	9.00e-105	375.00
IUUC-Aml-002107	Ailuropoda melanoleuca	85.45	0.00e+00	1864.00
IUUC-Atr-003017	Amborella trichopoda	38.12	2.00e-108	387.00
IUUC-Apl-003328	Anas platyrhynchos	86.41	0.00e+00	1811.00
IUUC-Aly-005794	Arabidopsis lyrata	38.57	1.00e-106	381.00
IUUC-Ath-007269	Arabidopsis thaliana	39.29	1.00e-109	390.00
IUUC-Bta-013547	Bos taurus	85.26	0.00e+00	1881.00
IUUC-Bdi-014502	Brachypodium distachyon	38.79	1.00e-108	387.00
IUUC-Bol-015093	Brassica oleracea	40.00	4.00e-111	396.00
IUUC-Bra-016722	Brassica rapa	40.00	6.00e-112	399.00
IUUC-Cel-018447	Caenorhabditis elegans	38.24	0.00e+00	681.00
IUUC-Cja-019855	Callithrix jacchus	85.26	0.00e+00	1857.00
IUUC-Cfa-020066	Canis familiaris	85.30	0.00e+00	1845.00
IUUC-Cpo-021504	Cavia porcellus	84.89	0.00e+00	1882.00
IUUC-Cre-022673	Chlamydomonas reinhardtii	35.67	1.00e-75	278.00
IUUC-Csa-023579	Chlorocebus sabaeus	85.45	0.00e+00	1862.00
IUUC-Cho-024430	Choloepus hoffmanni	74.36	0.00e+00	1343.00
IUUC-Cin-025750	Ciona intestinalis	47.17	0.00e+00	959.00
IUUC-Csv-026016	Ciona savignyi	47.75	0.00e+00	1004.00
IUUC-Dre-028271	Danio rerio	81.16	0.00e+00	1762.00
IUUC-Dno-029054	Dasypus novemcinctus	85.82	0.00e+00	1874.00
IUUC-Dor-030938	Dipodomys ordii	88.75	0.00e+00	1136.00
IUUC-Dme-031602	Drosophila melanogaster	47.15	0.00e+00	931.00
IUUC-Ete-033041	Echinops telfairi	70.00	0.00e+00	1247.00
IUUC-Eca-034411	Equus caballus	85.82	0.00e+00	1848.00
IUUC-Eeu-035201	Erinaceus europaeus	81.68	0.00e+00	779.00
IUUC-Fca-036594	Felis catus	84.51	0.00e+00	1830.00
IUUC-Fal-037317	Ficedula albicollis	83.17	0.00e+00	1843.00
IUUC-Gmo-039412	Gadus morhua	77.53	0.00e+00	1746.00
IUUC-Gga-040149	Gallus gallus	86.47	0.00e+00	1862.00
IUUC-Gac-042088	Gasterosteus aculeatus	81.12	0.00e+00	1832.00
IUUC-Gma-042728	Glycine max	40.14	2.00e-110	394.00
IUUC-Ggo-045279	Gorilla gorilla	85.45	0.00e+00	1859.00
IUUC-Hsa-045660	Homo sapiens	85.26	0.00e+00	1855.00
IUUC-Hvu-047102	Hordeum vulgare	38.90	2.00e-104	374.00
IUUC-Itr-048372	Ictidomys tridecemlineatus	97.60	0.00e+00	848.00
IUUC-Kpa-049307	Komagataella pastoris	32.52	1.00e-64	241.00
IUUC-Lch-050664	Latimeria chalumnae	82.57	0.00e+00	1834.00
IUUC-Lpe-050755	Leersia perrieri	36.94	6.00e-97	348.00
IUUC-Loc-052791	Lepisosteus oculatus	83.09	0.00e+00	1790.00
IUUC-Laf-053902	Loxodonta africana	86.01	0.00e+00	1880.00
IUUC-Mcc-054730	Macaca mulatta	85.45	0.00e+00	1862.00
IUUC-Meu-056527	Macropus eugenii	92.72	0.00e+00	1942.00
IUUC-Mpo-057570	Magnaporthe poae	35.21	1.00e-68	255.00
IUUC-Mtr-057671	Medicago truncatula	39.25	2.00e-110	394.00
IUUC-Mga-059260	Meleagris gallopavo	86.31	0.00e+00	1863.00
IUUC-Mmr-060804	Microcebus murinus	83.96	0.00e+00	1792.00
IUUC-Mdo-062575	Monodelphis domestica	93.38	0.00e+00	1983.00
IUUC-Mmu-063636	Mus musculus	83.58	0.00e+00	1788.00
IUUC-Mac-064989	Musa acuminata	38.48	1.00e-105	377.00
IUUC-Mpu-066677	Mustela putorius furo	84.54	0.00e+00	1734.00
IUUC-Mlu-067952	Myotis lucifugus	85.54	0.00e+00	1802.00
IUUC-Nle-069153	Nomascus leucogenys	85.54	0.00e+00	1860.00
IUUC-Opr-070554	Ochotona princeps	86.11	0.00e+00	1722.00
IUUC-Ont-071372	Oreochromis niloticus	81.62	0.00e+00	1793.00
IUUC-Oan-073327	Ornithorhynchus anatinus	69.52	0.00e+00	728.00
IUUC-Ocu-074183	Oryctolagus cuniculus	84.42	0.00e+00	1834.00
IUUC-Oba-075213	Oryza barthii	35.75	1.00e-105	377.00
IUUC-Obr-076320	Oryza brachyantha	38.57	2.00e-107	383.00
IUUC-Ogl-077093	Oryza glaberrima	35.90	4.00e-108	386.00
IUUC-Ogu-078947	Oryza glumaepatula	37.01	3.00e-110	393.00
IUUC-Oin-080058	Oryza indica	35.90	5.00e-108	385.00
IUUC-Olo-080742	Oryza longistaminata	35.52	3.00e-107	383.00
IUUC-Ome-081741	Oryza meridionalis	35.59	2.00e-101	363.00
IUUC-Oni-082385	Oryza nivara	37.01	3.00e-110	393.00
IUUC-Opu-083529	Oryza punctata	35.81	4.00e-108	385.00
IUUC-Oru-085128	Oryza rufipogon	33.87	9.00e-95	341.00
IUUC-Osa-085557	Oryza sativa	35.90	5.00e-108	385.00
IUUC-Ola-087337	Oryzias latipes	81.16	0.00e+00	1740.00
IUUC-Olu-087699	Ostreococcus lucimarinus	40.77	8.00e-80	290.00
IUUC-Oga-088342	Otolemur garnettii	84.72	0.00e+00	1776.00
IUUC-Oar-090234	Ovis aries	84.83	0.00e+00	1855.00
IUUC-Ptr-091661	Pan troglodytes	85.45	0.00e+00	1859.00
IUUC-Pan-092728	Papio anubis	85.18	0.00e+00	1855.00
IUUC-Psi-093251	Pelodiscus sinensis	85.53	0.00e+00	1729.00
IUUC-Pma-094195	Petromyzon marinus	70.38	0.00e+00	1456.00
IUUC-Pno-095132	Phaeosphaeria nodorum	33.92	7.00e-52	199.00
IUUC-Ppa-095544	Physcomitrella patens	38.03	2.00e-109	390.00
IUUC-Pfo-097472	Poecilia formosa	81.62	0.00e+00	1809.00
IUUC-Pab-098570	Pongo abelii	85.63	0.00e+00	1860.00
IUUC-Pop-098928	Populus trichocarpa	35.79	2.00e-98	353.00
IUUC-Pca-100110	Procavia capensis	74.81	0.00e+00	1567.00
IUUC-Ppe-101281	Prunus persica	38.12	7.00e-105	375.00
IUUC-Pva-102887	Pteropus vampyrus	81.08	0.00e+00	1729.00
IUUC-Pte-104105	Pyrenophora teres	35.46	2.00e-68	254.00
IUUC-Rno-106028	Rattus norvegicus	80.71	0.00e+00	1680.00
IUUC-Smo-109488	Selaginella moellendorffii	37.32	1.00e-105	378.00
IUUC-Sit-109811	Setaria italica	35.51	4.00e-109	389.00
IUUC-Sly-111362	Solanum lycopersicum	36.07	5.00e-102	365.00
IUUC-Sar-113287	Sorex araneus	69.37	5.00e-169	588.00
IUUC-Sbi-114433	Sorghum bicolor	35.14	6.00e-109	388.00
IUUC-Ssc-116103	Sus scrofa	86.10	0.00e+00	1857.00
IUUC-Tgu-117275	Taeniopygia guttata	85.91	0.00e+00	1844.00
IUUC-Tru-118681	Takifugu rubripes	79.85	0.00e+00	1814.00
IUUC-Tsy-118985	Tarsius syrichta	74.14	0.00e+00	853.00
IUUC-Tni-120850	Tetraodon nigroviridis	91.23	0.00e+00	774.00
IUUC-Tca-121770	Theobroma cacao	39.36	3.00e-110	393.00
IUUC-Tre-121892	Trichoderma reesei	36.38	9.00e-77	281.00
IUUC-Tae-125466	Triticum aestivum	36.25	1.00e-106	381.00
IUUC-Tur-126086	Triticum urartu	39.32	3.00e-104	373.00
IUUC-Tbe-127461	Tupaia belangeri	80.97	0.00e+00	1687.00
IUUC-Ttr-129269	Tursiops truncatus	84.89	0.00e+00	1824.00
IUUC-Vpa-130523	Vicugna pacos	74.17	6.00e-114	405.00
IUUC-Vvi-131524	Vitis vinifera	38.86	1.00e-107	384.00
IUUC-Xtr-132146	Xenopus tropicalis	84.06	0.00e+00	1848.00
IUUC-Xma-133526	Xiphophorus maculatus	81.25	0.00e+00	1800.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence