iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
fgenesh2_kg.1__4605__AT1G55860.1	fgenesh2_kg.1__4605__AT1G55860.1	fgenesh2_kg.1__4605__AT1G55860.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	4.60e-122	408.3	3550	3889
UBD/Alpha-Helix/UBA	7.40e-06	26.6	1520	1558
UBD/Alpha-Helix/UBM	3.60e-13	49.4	2847	2871

Active Site

Position(s)	Description	Evidence
3857	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGr 76
           ++dlk rl+v+f+gEeg+d+gG+tre+++lls+ ++++ + lf ++ ++++t+qpnp+s ++ +ehl++F+f+Gr
   Q: 3550 PQDLKGRLNVQFQGEEGIDAGGLTREWYQLLSRVIFDKGALLF-TTVGNDATFQPNPNSVYQ-TEHLSYFKFVGR 3622
           689************************************9999.556678889******986.5*********** PP
   S: 77   llgkalqdgrlldlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseei.... 147
           +++kal+dg+lld+ +++sfyk++lg+k++++d+e+vdp++yk+lk+++en   d++++ ldltfs++ ++    
   Q: 3623 MVAKALFDGQLLDVYFTRSFYKHILGVKVTYHDIEAVDPDYYKNLKWLLEN---DVSDI-LDLTFSMDADEekhi 3693
           *************************************************99...88887.888888666666688 PP
   S: 148  ...lgetkeeeLkpgGenipVtneNkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellic 219
                e++++eLkpgG+ni+Vt+e k+eYv+lv+ ++l++ i+ q++af eGfne+ip el+s+F+ +elelli+
   Q: 3694 lyeKTEVTDYELKPGGRNIRVTEETKHEYVDLVAGHILTNAIRPQINAFLEGFNELIPRELVSIFNDKELELLIS 3768
           95555566778**************************************************************** PP
   S: 220  GeeeidvedlkketkykggytedspaiqwFwevleefsseerkafLqFvTgssrlPlgGfaelk....prlfvir 290
           G +eid++dlk++t+y++ yt+ sp+i+wFwev+++fs+e+ ++fLqFvTg+s++Pl+Gf++l+    p++ +i+
   Q: 3769 GLPEIDFDDLKANTEYTS-YTAGSPVIHWFWEVVKAFSKEDMARFLQFVTGTSKVPLEGFKALQgisgPQRLQIH 3842
           ****************99.******************************************************** PP
   S: 291  k.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieet.kgFel 335
           k +++++rlPs++TCfn+L+LPeY+ske+l+e+Ll+Ai+e+ +gF++
   Q: 3843 KaYGAPERLPSAHTCFNQLDLPEYQSKEQLQERLLLAIHEAsEGFGF 3889
           *99999***************************************86 PP

UBD/Alpha-Helix/UBA

   S: 3    dedkleqlveMGFdreealqaLraa.nnnleaAveyLld 40
           de ++  +veMGF+r++a  aLr+   n++e+A+++L++
   Q: 1520 DETIVGMIVEMGFSRSRAEDALRRVgANSVEMAMDWLFT 1558
           677788899***************999***********8 PP

UBD/Alpha-Helix/UBM

   S: 4    qvDpeVfsqLPeeiQeEvmaelrqq 28
           ++Dpe++++LP++iQ Ev+a +r q
   Q: 2847 DIDPEFLAALPPDIQTEVLAQQRAQ 2871
           79******************99976 PP

Organism

Arabidopsis lyrata

Protein Sequence
(Fasta)

MAVAEEVTVF AETNLGTRIV MTVPLDITAA DFKRKLEKTH AICFSNLGEI QVHGLMVKRK 60
SSFYYLVESV PIKYIFRDNR KPWFIHAEAR AVSRSQELSV SNSIDKTHIR HCPGSDNSIE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTGTTG CAGAAGAGGT TACAGTCTTC GCTGAGACTA ACTTGGGAAC TAGAATCGTC 60
ATGACGGTTC CTCTGGATAT CACAGCAGCA GATTTCAAGA GTAAGCTCGA GACCACCCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0436--Ligase
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR011989--ARM-like
IPR016024--ARM-type_fold
IPR025527--DUF4414
IPR010309--E3_Ub_ligase_DUF908
IPR010314--E3_Ub_ligase_DUF913
IPR000569--HECT_dom
IPR015940--UBA
IPR009060--UBA-like
IPR003903--UIM_dom

PROSITE

PS50237--HECT
PS50030--UBA
PS50330--UIM

Pfam

PF14377--DUF4414
PF06012--DUF908
PF06025--DUF913
PF00632--HECT
PF00627--UBA

SMART

SM00119--HECTc
SM00165--UBA

Gene Ontology

GO:0016874--F:ligase activity
GO:0004842--F:ubiquitin-protein transferase activity

KEGG

aly:ARALYDRAFT_474651

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001684	Ailuropoda melanoleuca	51.77	2.00e-128	455.00
IUUC-Atr-003044	Amborella trichopoda	55.80	0.00e+00	3477.00
IUUC-Apl-003513	Anas platyrhynchos	45.20	1.00e-92	333.00
IUUC-Aca-005263	Anolis carolinensis	51.99	3.00e-129	457.00
IUUC-Ath-007472	Arabidopsis thaliana	94.21	0.00e+00	6482.00
IUUC-Ame-011067	Astyanax mexicanus	51.54	4.00e-127	451.00
IUUC-Bta-012813	Bos taurus	51.77	2.00e-128	455.00
IUUC-Bci-013995	Botrytis cinerea	46.00	2.00e-139	491.00
IUUC-Bra-016637	Brassica rapa	82.86	0.00e+00	5522.00
IUUC-Cel-018179	Caenorhabditis elegans	48.25	2.00e-119	424.00
IUUC-Cja-018741	Callithrix jacchus	51.88	8.00e-128	452.00
IUUC-Cfa-020083	Canis familiaris	51.77	2.00e-128	455.00
IUUC-Cpo-021923	Cavia porcellus	44.04	4.00e-95	344.00
IUUC-Csa-023853	Chlorocebus sabaeus	51.77	1.00e-128	455.00
IUUC-Cho-024718	Choloepus hoffmanni	55.24	5.00e-119	423.00
IUUC-Csv-025872	Ciona savignyi	49.55	1.00e-119	422.00
IUUC-Cne-027095	Cryptococcus neoformans	40.24	2.00e-109	391.00
IUUC-Dre-028525	Danio rerio	50.00	1.00e-112	402.00
IUUC-Dno-029680	Dasypus novemcinctus	51.77	2.00e-128	454.00
IUUC-Dor-030902	Dipodomys ordii	46.46	3.00e-109	391.00
IUUC-Dme-032122	Drosophila melanogaster	48.99	4.00e-122	434.00
IUUC-Eca-033915	Equus caballus	51.22	2.00e-126	448.00
IUUC-Eeu-034963	Erinaceus europaeus	51.43	1.00e-126	449.00
IUUC-Fca-035824	Felis catus	51.77	2.00e-128	454.00
IUUC-Fal-037275	Ficedula albicollis	45.45	3.00e-93	335.00
IUUC-Gmo-039073	Gadus morhua	51.77	1.00e-128	455.00
IUUC-Gga-040309	Gallus gallus	57.32	1.00e-98	351.00
IUUC-Gac-042430	Gasterosteus aculeatus	51.77	2.00e-128	455.00
IUUC-Gma-043112	Glycine max	62.09	0.00e+00	3892.00
IUUC-Hsa-046879	Homo sapiens	51.77	2.00e-128	455.00
IUUC-Itr-048430	Ictidomys tridecemlineatus	51.77	1.00e-128	454.00
IUUC-Lch-050252	Latimeria chalumnae	51.88	7.00e-128	452.00
IUUC-Lpe-050915	Leersia perrieri	53.38	0.00e+00	3251.00
IUUC-Loc-052472	Lepisosteus oculatus	51.55	2.00e-128	455.00
IUUC-Laf-054154	Loxodonta africana	51.77	1.00e-128	455.00
IUUC-Mcc-055085	Macaca mulatta	51.77	2.00e-128	455.00
IUUC-Meu-056436	Macropus eugenii	40.40	3.00e-77	282.00
IUUC-Mor-057201	Magnaporthe oryzae	42.95	5.00e-133	470.00
IUUC-Mtr-058128	Medicago truncatula	60.80	0.00e+00	3831.00
IUUC-Mga-059481	Meleagris gallopavo	45.20	2.00e-93	335.00
IUUC-Mmr-060820	Microcebus murinus	51.77	1.00e-128	456.00
IUUC-Mdo-062930	Monodelphis domestica	51.77	9.00e-129	456.00
IUUC-Mmu-063601	Mus musculus	51.77	1.00e-128	456.00
IUUC-Mac-065557	Musa acuminata	47.55	0.00e+00	1287.00
IUUC-Mpu-066653	Mustela putorius furo	51.77	3.00e-128	454.00
IUUC-Mlu-067418	Myotis lucifugus	51.77	2.00e-128	455.00
IUUC-Nle-069418	Nomascus leucogenys	51.77	2.00e-128	454.00
IUUC-Ont-071300	Oreochromis niloticus	51.77	2.00e-128	455.00
IUUC-Oan-073046	Ornithorhynchus anatinus	51.54	2.00e-127	451.00
IUUC-Ocu-074178	Oryctolagus cuniculus	51.77	1.00e-128	455.00
IUUC-Oba-075252	Oryza barthii	51.45	0.00e+00	2026.00
IUUC-Obr-076762	Oryza brachyantha	51.28	0.00e+00	2052.00
IUUC-Ogl-077590	Oryza glaberrima	53.65	0.00e+00	1115.00
IUUC-Ogu-077981	Oryza glumaepatula	51.44	0.00e+00	1984.00
IUUC-Oin-079663	Oryza indica	49.07	0.00e+00	1781.00
IUUC-Olo-080326	Oryza longistaminata	51.45	0.00e+00	2027.00
IUUC-Ome-081289	Oryza meridionalis	66.59	0.00e+00	1040.00
IUUC-Oni-082342	Oryza nivara	51.43	0.00e+00	2048.00
IUUC-Opu-083428	Oryza punctata	51.30	0.00e+00	1995.00
IUUC-Oru-084559	Oryza rufipogon	51.45	0.00e+00	2021.00
IUUC-Osa-086200	Oryza sativa	64.62	0.00e+00	1203.00
IUUC-Olu-087813	Ostreococcus lucimarinus	51.34	6.00e-125	439.00
IUUC-Oga-088903	Otolemur garnettii	51.77	2.00e-128	455.00
IUUC-Oar-090210	Ovis aries	51.77	1.00e-128	455.00
IUUC-Pan-092368	Papio anubis	50.24	1.00e-113	406.00
IUUC-Ppa-095834	Physcomitrella patens	46.81	0.00e+00	1628.00
IUUC-Pfo-096232	Poecilia formosa	51.77	1.00e-128	455.00
IUUC-Pab-098583	Pongo abelii	51.77	2.00e-128	454.00
IUUC-Pop-099520	Populus trichocarpa	63.31	0.00e+00	4165.00
IUUC-Pca-100596	Procavia capensis	43.94	3.00e-87	316.00
IUUC-Ppe-102109	Prunus persica	65.32	0.00e+00	4259.00
IUUC-Pva-102116	Pteropus vampyrus	47.67	1.00e-113	405.00
IUUC-Pte-104018	Pyrenophora teres	31.99	7.00e-142	499.00
IUUC-Sha-106961	Sarcophilus harrisii	51.77	1.00e-128	456.00
IUUC-Ssl-108514	Sclerotinia sclerotiorum	45.52	3.00e-96	345.00
IUUC-Smo-109428	Selaginella moellendorffii	44.03	0.00e+00	1463.00
IUUC-Sit-110149	Setaria italica	50.42	0.00e+00	1891.00
IUUC-Sly-111285	Solanum lycopersicum	61.56	0.00e+00	4039.00
IUUC-Stu-112501	Solanum tuberosum	69.79	1.00e-127	448.00
IUUC-Sar-113291	Sorex araneus	52.86	9.00e-124	439.00
IUUC-Sbi-113794	Sorghum bicolor	48.37	0.00e+00	1943.00
IUUC-Ssc-115754	Sus scrofa	51.77	2.00e-128	455.00
IUUC-Tgu-116632	Taeniopygia guttata	43.54	8.00e-93	334.00
IUUC-Tru-118570	Takifugu rubripes	51.77	1.00e-128	456.00
IUUC-Tni-120836	Tetraodon nigroviridis	50.88	8.00e-125	442.00
IUUC-Tca-121646	Theobroma cacao	66.16	0.00e+00	4293.00
IUUC-Tbe-127793	Tupaia belangeri	36.14	1.00e-84	306.00
IUUC-Ttr-129253	Tursiops truncatus	51.77	2.00e-128	455.00
IUUC-Vda-129886	Verticillium dahliae	47.95	7.00e-136	479.00
IUUC-Vpa-130708	Vicugna pacos	51.77	4.00e-128	454.00
IUUC-Vvi-131559	Vitis vinifera	66.00	0.00e+00	1748.00
IUUC-Xtr-132123	Xenopus tropicalis	49.46	1.00e-115	412.00
IUUC-Xma-133869	Xiphophorus maculatus	51.77	1.00e-128	456.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence