iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPSIG00000004623.1	ENSPSIT00000004998.1	ENSPSIP00000004970.1
ENSPSIG00000004623.1	ENSPSIT00000005005.1	ENSPSIP00000004977.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	6.30e-13	48.5	517	566

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 7    qvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           ++lydy+a+ dde ++   d+++ i  e  d gW++g    +g+ GlfP+n+ve
   Q: 517  IALYDYQAAGDDEISFDPDDIITNI--EMIDDGWWRG--VCKGRYGLFPANYVE 566
           79***********************..9*********..7************97 PP

Organism

Pelodiscus sinensis

Protein Sequence
(Fasta)

LMVFQMWKAT AGHTISVSQN DGADDWETDP DFVNDVSEKE QRWGAKTVQG SGHQEHIKSI 60
HQLRENVFQE HQSLKEKELE TGPKASRGYG GKFGVEQDRM DKSAVGHEYQ SKLSKHCSQV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCAGTTTGA CCAGCCTGAC TTGGTGCACT AAGCAATACA GATGTGGAAA TAACTCCACG 60
GGGCAGCAGA AGGCAGGCAC AGCACTAGCG CGCGACTCGG CGTGCATGAT TCATGGGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR015503--Cortactin
IPR003134--Hs1_Cortactin
IPR001452--SH3_domain

PROSITE

PS51090--CORTACTIN
PS50002--SH3

Pfam

PF02218--HS1_rep
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3

Gene Ontology

GO:0005884--C:actin filament
GO:0030863--C:cortical cytoskeleton
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0005925--C:focal adhesion
GO:0005794--C:Golgi apparatus
GO:0030027--C:lamellipodium
GO:1990023--C:mitotic spindle midzone
GO:0002102--C:podosome
GO:0001726--C:ruffle
GO:0008076--C:voltage-gated potassium channel complex
GO:0030041--P:actin filament polymerization
GO:0097062--P:dendritic spine maintenance
GO:0006886--P:intracellular protein transport
GO:2001237--P:negative regulation of extrinsic apoptotic signaling pathway
GO:0030838--P:positive regulation of actin filament polymerization
GO:0045987--P:positive regulation of smooth muscle contraction
GO:1903146--P:regulation of mitophagy
GO:0006930--P:substrate-dependent cell migration, cell extension

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002064	Ailuropoda melanoleuca	79.23	0.00e+00	863.00
IUUC-Apl-003745	Anas platyrhynchos	87.50	0.00e+00	862.00
IUUC-Aca-004438	Anolis carolinensis	86.12	0.00e+00	952.00
IUUC-Bgr-012041	Blumeria graminis	57.89	6.00e-16	79.30
IUUC-Bta-013563	Bos taurus	81.24	0.00e+00	826.00
IUUC-Bci-013690	Botrytis cinerea	58.82	4.00e-12	66.60
IUUC-Cfa-020718	Canis familiaris	79.79	0.00e+00	857.00
IUUC-Cpo-022303	Cavia porcellus	80.88	0.00e+00	904.00
IUUC-Csa-023431	Chlorocebus sabaeus	80.53	0.00e+00	843.00
IUUC-Cin-025677	Ciona intestinalis	61.43	1.00e-119	423.00
IUUC-Csv-026140	Ciona savignyi	63.06	3.00e-108	385.00
IUUC-Dre-028012	Danio rerio	71.87	1.00e-146	513.00
IUUC-Dno-029332	Dasypus novemcinctus	68.85	0.00e+00	682.00
IUUC-Dse-031182	Dothistroma septosporum	36.11	2.00e-11	64.70
IUUC-Eca-033801	Equus caballus	82.25	0.00e+00	855.00
IUUC-Fca-035633	Felis catus	78.67	0.00e+00	716.00
IUUC-Fal-036775	Ficedula albicollis	84.42	0.00e+00	829.00
IUUC-Gmo-038507	Gadus morhua	71.43	3.00e-20	92.80
IUUC-Ggr-039882	Gaeumannomyces graminis	50.94	8.00e-11	62.40
IUUC-Gga-040568	Gallus gallus	86.99	0.00e+00	893.00
IUUC-Gac-042253	Gasterosteus aculeatus	56.52	2.00e-116	412.00
IUUC-Hsa-046818	Homo sapiens	81.06	0.00e+00	848.00
IUUC-Itr-048833	Ictidomys tridecemlineatus	72.87	0.00e+00	756.00
IUUC-Lch-050199	Latimeria chalumnae	72.88	6.00e-150	523.00
IUUC-Loc-052855	Lepisosteus oculatus	74.51	4.00e-151	527.00
IUUC-Laf-053866	Loxodonta africana	83.92	0.00e+00	917.00
IUUC-Mcc-055515	Macaca mulatta	80.35	0.00e+00	839.00
IUUC-Mga-059791	Meleagris gallopavo	93.37	0.00e+00	653.00
IUUC-Mmr-061147	Microcebus murinus	74.69	0.00e+00	753.00
IUUC-Mdo-062660	Monodelphis domestica	60.56	2.00e-173	603.00
IUUC-Mmu-064023	Mus musculus	79.29	0.00e+00	836.00
IUUC-Mpu-065867	Mustela putorius furo	80.73	1.00e-167	582.00
IUUC-Mlu-067704	Myotis lucifugus	68.78	0.00e+00	676.00
IUUC-Ont-071873	Oreochromis niloticus	79.28	3.00e-167	581.00
IUUC-Oan-073528	Ornithorhynchus anatinus	80.54	4.00e-170	590.00
IUUC-Oga-088028	Otolemur garnettii	80.35	0.00e+00	839.00
IUUC-Oar-090203	Ovis aries	72.68	0.00e+00	700.00
IUUC-Pan-092594	Papio anubis	76.32	0.00e+00	789.00
IUUC-Pma-094161	Petromyzon marinus	46.17	1.00e-84	306.00
IUUC-Pfo-097391	Poecilia formosa	55.15	2.00e-112	399.00
IUUC-Pab-097913	Pongo abelii	74.16	0.00e+00	741.00
IUUC-Pte-104156	Pyrenophora teres	56.86	1.00e-11	65.10
IUUC-Rno-105489	Rattus norvegicus	79.12	0.00e+00	813.00
IUUC-Sha-107308	Sarcophilus harrisii	70.07	0.00e+00	676.00
IUUC-Tgu-117049	Taeniopygia guttata	77.48	0.00e+00	753.00
IUUC-Tru-118718	Takifugu rubripes	75.70	9.00e-159	553.00
IUUC-Tni-120535	Tetraodon nigroviridis	68.45	4.00e-145	507.00
IUUC-Tme-127196	Tuber melanosporum	59.65	6.00e-15	75.90
IUUC-Xtr-131797	Xenopus tropicalis	62.78	2.00e-129	455.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence