iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004661

UUCD1 version

UUC-AnC-00897

Ensembl Protein ID

ENSACAP00000020901.1

UniProt Accession

G1KYH1; G1KYH1_ANOCA

Protein Name

Uncharacterized protein

Gene Name

LOC100567594

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000023169.2	ENSACAT00000023904.2	ENSACAP00000020901.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	5.10e-06	26.9	18	57
ULD/UDP/UFD/RAWUL	8.70e-31	106.2	131	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           C iC   f d + +  C H f+++C+ ++        ++ +CP+C+
   Q: 18   CVICGGYFIDATTIIECLHSFCKTCIVHY------LETSKYCPICD 57
           ********99999****************......**********5 PP

ULD/UDP/UFD/RAWUL

   S: 1    islsLeplesnkakddsk..........lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwkkeg 79
           isls+e++++n+ +++ +          ++k+ylrc+a++tV+hl+kfl++k+++++s+++d+++e+e+L+d++tL++i+yi++w+++g
   Q: 131  ISLSIEFFDQNRLERKGNkekekskeevNDKRYLRCPAAMTVMHLRKFLRSKMDIPNSFQIDVMYEEEPLKDYYTLMDIAYIYTWRRNG 219
           6788888888877665555677788999************************************************************* PP
   S: 80   pLvLqYr 86
           pL+L+Yr
   Q: 220  PLPLKYR 226
           ******9 PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MHRTTRLKIT ELNPHLMCVI CGGYFIDATT IIECLHSFCK TCIVHYLETS KYCPICDVQV 60
HKTRPLLNIR SDKTLQDIVY KLVPGLFKNE MKRRRDFYAA HPSADAANGS NEDRGEVADE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGAGGGAG GGAAGGGGGG GGAGGAGGAG GCTCCGGATC CGCGGCGGGA TTGGGTCACG 60
GCGAGGCTGG CGGGGCTGCG GCTCCTCCGA CACTAATTCC CAGGCCACCC TTAAGGAATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0000792--C:heterochromatin
GO:0016604--C:nuclear body
GO:0031519--C:PcG protein complex
GO:0000151--C:ubiquitin ligase complex
GO:1990841--F:promoter-specific chromatin binding
GO:0000978--F:RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0097027--F:ubiquitin-protein transferase activator activity
GO:0008270--F:zinc ion binding
GO:0007420--P:brain development
GO:0006306--P:DNA methylation
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0016573--P:histone acetylation
GO:0016574--P:histone ubiquitination
GO:0006959--P:humoral immune response
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0030890--P:positive regulation of B cell proliferation
GO:0033092--P:positive regulation of immature T cell proliferation in thymus
GO:2000011--P:regulation of adaxial/abaxial pattern formation
GO:0021903--P:rostrocaudal neural tube patterning
GO:0048103--P:somatic stem cell division

KEGG

acs:100567594

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001498	Ailuropoda melanoleuca	84.71	4.00e-145	506.00
IUUC-Apl-004208	Anas platyrhynchos	84.38	2.00e-119	421.00
IUUC-Ath-007649	Arabidopsis thaliana	43.75	1.00e-12	67.40
IUUC-Ame-010610	Astyanax mexicanus	69.79	2.00e-126	445.00
IUUC-Bta-012606	Bos taurus	85.03	8.00e-145	506.00
IUUC-Cja-019482	Callithrix jacchus	84.39	9.00e-149	519.00
IUUC-Cfa-020482	Canis familiaris	84.71	4.00e-145	506.00
IUUC-Cpo-022061	Cavia porcellus	84.39	8.00e-149	519.00
IUUC-Csa-024102	Chlorocebus sabaeus	84.71	4.00e-150	524.00
IUUC-Cho-025081	Choloepus hoffmanni	76.52	1.00e-100	358.00
IUUC-Cin-025612	Ciona intestinalis	48.58	1.00e-51	196.00
IUUC-Dre-027929	Danio rerio	74.15	2.00e-129	454.00
IUUC-Dno-029797	Dasypus novemcinctus	87.30	6.00e-152	529.00
IUUC-Dor-030256	Dipodomys ordii	82.17	5.00e-143	499.00
IUUC-Dme-031904	Drosophila melanogaster	44.59	3.00e-51	197.00
IUUC-Ete-033148	Echinops telfairi	63.36	5.00e-79	286.00
IUUC-Eca-033318	Equus caballus	85.03	4.00e-145	506.00
IUUC-Eeu-034547	Erinaceus europaeus	72.29	7.00e-120	423.00
IUUC-Fca-035866	Felis catus	84.71	1.00e-144	505.00
IUUC-Fal-036660	Ficedula albicollis	85.58	2.00e-143	501.00
IUUC-Gmo-039341	Gadus morhua	81.42	1.00e-122	432.00
IUUC-Gga-040611	Gallus gallus	86.94	3.00e-148	517.00
IUUC-Gac-041888	Gasterosteus aculeatus	66.47	1.00e-120	426.00
IUUC-Ggo-045027	Gorilla gorilla	84.71	3.00e-149	520.00
IUUC-Hsa-045665	Homo sapiens	84.71	6.00e-150	523.00
IUUC-Itr-049045	Ictidomys tridecemlineatus	83.12	5.00e-148	516.00
IUUC-Lch-049714	Latimeria chalumnae	78.90	3.00e-146	510.00
IUUC-Loc-052161	Lepisosteus oculatus	77.61	2.00e-136	478.00
IUUC-Laf-054108	Loxodonta africana	83.96	9.00e-149	519.00
IUUC-Mcc-055562	Macaca mulatta	84.71	5.00e-150	523.00
IUUC-Meu-056709	Macropus eugenii	84.36	3.00e-147	513.00
IUUC-Mga-060104	Meleagris gallopavo	86.35	1.00e-104	372.00
IUUC-Mmr-061191	Microcebus murinus	84.71	4.00e-150	524.00
IUUC-Mdo-062711	Monodelphis domestica	87.05	8.00e-135	472.00
IUUC-Mmu-064255	Mus musculus	81.53	5.00e-142	496.00
IUUC-Mpu-066466	Mustela putorius furo	84.71	2.00e-145	508.00
IUUC-Mlu-067622	Myotis lucifugus	84.08	3.00e-148	517.00
IUUC-Nle-069253	Nomascus leucogenys	84.71	5.00e-150	523.00
IUUC-Opr-070511	Ochotona princeps	84.08	3.00e-148	517.00
IUUC-Ont-072177	Oreochromis niloticus	81.61	1.00e-122	432.00
IUUC-Oan-073336	Ornithorhynchus anatinus	84.66	1.00e-145	508.00
IUUC-Ocu-074113	Oryctolagus cuniculus	84.39	1.00e-144	505.00
IUUC-Ola-087057	Oryzias latipes	83.90	5.00e-119	420.00
IUUC-Oga-088346	Otolemur garnettii	84.71	3.00e-149	520.00
IUUC-Oar-089843	Ovis aries	85.03	8.00e-145	506.00
IUUC-Ptr-090486	Pan troglodytes	84.71	3.00e-149	520.00
IUUC-Pan-092667	Papio anubis	92.02	4.00e-140	490.00
IUUC-Psi-093469	Pelodiscus sinensis	84.97	3.00e-152	530.00
IUUC-Pma-094481	Petromyzon marinus	72.43	8.00e-88	315.00
IUUC-Ppa-095526	Physcomitrella patens	40.22	1.00e-09	57.80
IUUC-Pfo-097156	Poecilia formosa	75.42	9.00e-127	446.00
IUUC-Pab-097670	Pongo abelii	84.71	3.00e-149	520.00
IUUC-Pva-102800	Pteropus vampyrus	84.71	3.00e-149	520.00
IUUC-Rno-105128	Rattus norvegicus	80.89	7.00e-143	499.00
IUUC-Sha-106747	Sarcophilus harrisii	84.05	3.00e-142	497.00
IUUC-Sar-113416	Sorex araneus	84.39	2.00e-149	521.00
IUUC-Ssc-115864	Sus scrofa	84.71	1.00e-149	521.00
IUUC-Tgu-116851	Taeniopygia guttata	83.68	4.00e-121	427.00
IUUC-Tru-117698	Takifugu rubripes	82.10	7.00e-119	419.00
IUUC-Tsy-119590	Tarsius syrichta	84.39	1.00e-148	518.00
IUUC-Tni-120170	Tetraodon nigroviridis	81.61	1.00e-121	428.00
IUUC-Tbe-127790	Tupaia belangeri	84.39	2.00e-149	521.00
IUUC-Ttr-129316	Tursiops truncatus	87.62	6.00e-149	519.00
IUUC-Vpa-130669	Vicugna pacos	85.03	5.00e-145	506.00
IUUC-Xtr-131912	Xenopus tropicalis	79.20	4.00e-135	473.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence