iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Cpo-022047

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAKN02033120

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCPOG00000022966.1	ENSCPOT00000027536.1	ENSCPOP00000019980.1

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	91.46	0.00e+00	661.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Cavia porcellus

Protein Sequence
(Fasta)

LTFPSFLPIP DFTMWATCCN WFCLDGQPEE VPPPQGAMAQ AYSNPGYSSF PSPTGLEPSC 60
KACGAHFAST SRKQTCLDCK KHFCMTCSSQ EGNGPRLCLL CQRFRATAFQ REELMKMKVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTGACCTTTC CCTCTTTCCT CCCCATACCA GATTTTACCA TGTGGGCAAC CTGCTGCAAC 60
TGGTTCTGCC TGGATGGACA GCCTGAAGAG GTCCCACCAC CCCAGGGAGC CATGGCACAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	88.25	6.00e-180	622.00
IUUC-Apl-004124	Anas platyrhynchos	66.22	4.00e-124	437.00
IUUC-Aly-005548	Arabidopsis lyrata	43.86	1.00e-08	55.50
IUUC-Ame-011616	Astyanax mexicanus	57.88	4.00e-103	367.00
IUUC-Bta-012374	Bos taurus	83.61	8.00e-174	602.00
IUUC-Cja-019780	Callithrix jacchus	89.84	0.00e+00	655.00
IUUC-Cfa-021252	Canis familiaris	89.34	0.00e+00	630.00
IUUC-Csa-023161	Chlorocebus sabaeus	91.18	0.00e+00	672.00
IUUC-Cho-024316	Choloepus hoffmanni	89.44	6.00e-153	533.00
IUUC-Dre-028596	Danio rerio	56.44	4.00e-110	390.00
IUUC-Dno-029333	Dasypus novemcinctus	90.36	0.00e+00	654.00
IUUC-Ete-033163	Echinops telfairi	83.47	6.00e-166	576.00
IUUC-Eca-033994	Equus caballus	90.16	0.00e+00	659.00
IUUC-Eeu-035162	Erinaceus europaeus	84.33	5.00e-127	446.00
IUUC-Fca-036418	Felis catus	87.40	0.00e+00	659.00
IUUC-Fal-037427	Ficedula albicollis	65.22	1.00e-129	456.00
IUUC-Gga-041053	Gallus gallus	67.49	3.00e-128	451.00
IUUC-Ggo-045436	Gorilla gorilla	91.46	0.00e+00	672.00
IUUC-Hsa-045798	Homo sapiens	91.46	0.00e+00	672.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	90.11	0.00e+00	649.00
IUUC-Lch-050639	Latimeria chalumnae	62.26	7.00e-124	436.00
IUUC-Laf-053355	Loxodonta africana	86.99	2.00e-175	607.00
IUUC-Mcc-055222	Macaca mulatta	91.74	0.00e+00	655.00
IUUC-Meu-056692	Macropus eugenii	76.03	1.00e-153	535.00
IUUC-Mga-059298	Meleagris gallopavo	67.12	2.00e-128	451.00
IUUC-Mmr-061792	Microcebus murinus	87.05	5.00e-180	623.00
IUUC-Mdo-062986	Monodelphis domestica	78.47	1.00e-160	558.00
IUUC-Mmu-063356	Mus musculus	88.80	0.00e+00	636.00
IUUC-Mpu-066273	Mustela putorius furo	88.47	0.00e+00	663.00
IUUC-Mlu-066953	Myotis lucifugus	88.80	0.00e+00	640.00
IUUC-Nle-070075	Nomascus leucogenys	90.16	0.00e+00	671.00
IUUC-Opr-070838	Ochotona princeps	87.60	2.00e-179	621.00
IUUC-Ont-071967	Oreochromis niloticus	73.43	2.00e-55	209.00
IUUC-Ocu-074807	Oryctolagus cuniculus	87.98	0.00e+00	647.00
IUUC-Ola-086903	Oryzias latipes	68.46	8.00e-56	211.00
IUUC-Oga-088536	Otolemur garnettii	87.05	2.00e-173	601.00
IUUC-Oar-089838	Ovis aries	84.51	2.00e-175	608.00
IUUC-Ptr-090962	Pan troglodytes	91.18	0.00e+00	672.00
IUUC-Pan-092853	Papio anubis	90.63	0.00e+00	669.00
IUUC-Psi-093164	Pelodiscus sinensis	64.11	2.00e-124	438.00
IUUC-Pma-094104	Petromyzon marinus	44.24	2.00e-54	206.00
IUUC-Pno-094968	Phaeosphaeria nodorum	36.73	2.00e-08	56.20
IUUC-Pab-098304	Pongo abelii	90.71	0.00e+00	674.00
IUUC-Pca-100316	Procavia capensis	87.33	1.00e-172	598.00
IUUC-Ppe-101490	Prunus persica	36.59	8.00e-09	55.10
IUUC-Pva-102612	Pteropus vampyrus	75.21	7.00e-149	520.00
IUUC-Rno-105449	Rattus norvegicus	89.53	0.00e+00	631.00
IUUC-Sha-107578	Sarcophilus harrisii	78.36	6.00e-152	530.00
IUUC-Sar-113638	Sorex araneus	84.02	8.00e-171	592.00
IUUC-Ssc-116401	Sus scrofa	88.25	0.00e+00	655.00
IUUC-Tru-118765	Takifugu rubripes	49.04	7.00e-78	283.00
IUUC-Tsy-118850	Tarsius syrichta	87.46	3.00e-150	523.00
IUUC-Tbe-128086	Tupaia belangeri	82.09	3.00e-169	587.00
IUUC-Ttr-128249	Tursiops truncatus	68.60	5.00e-138	483.00
IUUC-Vpa-130816	Vicugna pacos	88.37	3.00e-41	162.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence