iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ptr-090962

UUCD1 version

UUC-PaT-00333

Ensembl Protein ID

ENSPTRP00000015366.3

UniProt Accession

H2QCP1; H2QCP1_PANTR

Genbank Protein ID

JAA30197.1; JAA33479.1

Protein Name

Ring finger and FYVE-like domain containing 1

Genbank Nucleotide ID

AACZ03109006; GABE01011260

Gene Name

RFFL

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPTRG00000009009.6	ENSPTRT00000016601.3	ENSPTRP00000015366.3

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	99.72	0.00e+00	755.00	IUUC-Hsa-045798

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Pan troglodytes

Protein Sequence
(Fasta)

MWATCCNWFC LDGQPEEVPP PQGARMQAYS NPGYSSFPSP TGLEPSCKSC GAHFANTARK 60
QTCLDCKKNF CMTCSSQVGN GPRLCLLCQR FRATAFQREE LMKMKVKDLR DYLSLHDIST 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TTACCAAAGA TACATCCCCA GGCGGCACCA TTCACTTCAC TTGAAAGCCG CTGCTCTTGG 60
TTCCTGAGAT GATCTCATCT GAACATGGCT CCAGCGACCT CAGCCACAGG AACTAGAGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001370--BIR_rpt
IPR003034--SAP_dom
IPR011011--Znf_FYVE_PHD
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

SMART

SM00184--RING

Gene Ontology

GO:0010008--C:endosome membrane
GO:0005886--C:plasma membrane
GO:0002947--C:tumor necrosis factor receptor superfamily complex
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:2001271--P:negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis
GO:1902042--P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1901797--P:negative regulation of signal transduction by p53 class mediator
GO:0010804--P:negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0070936--P:protein K48-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

ptr:454582

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001630	Ailuropoda melanoleuca	90.36	0.00e+00	637.00
IUUC-Apl-004124	Anas platyrhynchos	66.30	1.00e-125	442.00
IUUC-Aly-005548	Arabidopsis lyrata	47.06	1.00e-08	55.50
IUUC-Ame-011616	Astyanax mexicanus	59.67	9.00e-105	373.00
IUUC-Bta-012374	Bos taurus	86.23	0.00e+00	634.00
IUUC-Cja-019780	Callithrix jacchus	95.05	0.00e+00	688.00
IUUC-Cfa-021252	Canis familiaris	92.29	0.00e+00	646.00
IUUC-Cpo-022047	Cavia porcellus	91.18	0.00e+00	660.00
IUUC-Csa-023161	Chlorocebus sabaeus	98.07	0.00e+00	742.00
IUUC-Cho-024316	Choloepus hoffmanni	91.42	4.00e-157	546.00
IUUC-Cne-026858	Cryptococcus neoformans	25.15	7.00e-07	48.50
IUUC-Dre-028596	Danio rerio	55.92	4.00e-109	387.00
IUUC-Dno-029333	Dasypus novemcinctus	93.11	0.00e+00	670.00
IUUC-Ete-033163	Echinops telfairi	83.47	5.00e-166	576.00
IUUC-Eca-033994	Equus caballus	92.29	0.00e+00	678.00
IUUC-Eeu-035162	Erinaceus europaeus	87.00	2.00e-131	461.00
IUUC-Fca-036418	Felis catus	91.18	0.00e+00	694.00
IUUC-Fal-037427	Ficedula albicollis	65.40	2.00e-133	468.00
IUUC-Gga-041053	Gallus gallus	67.49	5.00e-132	463.00
IUUC-Ggo-045436	Gorilla gorilla	99.72	0.00e+00	755.00
IUUC-Hsa-045798	Homo sapiens	99.72	0.00e+00	755.00
IUUC-Itr-048077	Ictidomys tridecemlineatus	91.74	0.00e+00	649.00
IUUC-Lch-050639	Latimeria chalumnae	62.53	5.00e-126	443.00
IUUC-Laf-053355	Loxodonta africana	89.62	0.00e+00	629.00
IUUC-Mcc-055222	Macaca mulatta	97.52	0.00e+00	687.00
IUUC-Meu-056692	Macropus eugenii	78.24	9.00e-160	555.00
IUUC-Mga-059298	Meleagris gallopavo	66.39	9.00e-131	459.00
IUUC-Mmr-061792	Microcebus murinus	90.08	0.00e+00	641.00
IUUC-Mdo-062986	Monodelphis domestica	81.82	5.00e-171	593.00
IUUC-Mmu-063356	Mus musculus	89.81	0.00e+00	651.00
IUUC-Mpu-066273	Mustela putorius furo	91.46	0.00e+00	694.00
IUUC-Mlu-066953	Myotis lucifugus	91.74	0.00e+00	681.00
IUUC-Nle-070075	Nomascus leucogenys	98.35	0.00e+00	747.00
IUUC-Opr-070838	Ochotona princeps	89.26	0.00e+00	642.00
IUUC-Ont-071967	Oreochromis niloticus	50.96	6.00e-92	330.00
IUUC-Ocu-074807	Oryctolagus cuniculus	90.63	0.00e+00	681.00
IUUC-Obr-076159	Oryza brachyantha	41.07	4.00e-08	50.40
IUUC-Ola-086903	Oryzias latipes	48.40	6.00e-86	310.00
IUUC-Oga-088536	Otolemur garnettii	90.36	0.00e+00	629.00
IUUC-Oar-089838	Ovis aries	86.23	7.00e-179	619.00
IUUC-Pan-092853	Papio anubis	97.52	0.00e+00	739.00
IUUC-Psi-093164	Pelodiscus sinensis	65.48	3.00e-127	447.00
IUUC-Pma-094104	Petromyzon marinus	44.65	3.00e-57	215.00
IUUC-Pno-094968	Phaeosphaeria nodorum	36.73	2.00e-08	56.20
IUUC-Pab-098304	Pongo abelii	98.90	0.00e+00	748.00
IUUC-Pca-100316	Procavia capensis	89.53	3.00e-178	617.00
IUUC-Ppe-101490	Prunus persica	37.80	1.00e-09	57.80
IUUC-Pva-102612	Pteropus vampyrus	78.24	9.00e-159	552.00
IUUC-Rno-105449	Rattus norvegicus	90.63	0.00e+00	649.00
IUUC-Sha-107578	Sarcophilus harrisii	80.44	5.00e-158	550.00
IUUC-Sar-113638	Sorex araneus	86.23	7.00e-176	609.00
IUUC-Ssc-116401	Sus scrofa	90.63	0.00e+00	685.00
IUUC-Tru-118765	Takifugu rubripes	49.86	7.00e-83	300.00
IUUC-Tsy-118850	Tarsius syrichta	90.76	8.00e-155	539.00
IUUC-Tbe-128086	Tupaia belangeri	85.12	0.00e+00	628.00
IUUC-Ttr-128249	Tursiops truncatus	69.15	4.00e-139	487.00
IUUC-Vpa-130816	Vicugna pacos	87.21	5.00e-41	160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence