iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Mga-059300

UUCD1 version

UUC-MeG-00835

Ensembl Protein ID

ENSMGAP00000002043.1

UniProt Accession

G1MU67; G1MU67_MELGA

Protein Name

Uncharacterized protein

Gene Name

USP4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000002305.1	ENSMGAT00000002716.1	ENSMGAP00000002043.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.90e-116	386.3	259	875
ULD/UDP/UBQ/UBQ_Other	6.70e-11	41.7	100	177

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l++++le k++ ++n++np ++ ge+++++++l++++w++++++v+pr+++++++++a++fsgy+
   Q: 259  CGLSNLGNTCFMNSALQCLSNTPPLTDYFLEdKYEAEINHSNPLGMRGEIAEAYAELIKQIWSGRQSHVAPRMFKTQVGRFAPQFSGYQ 347
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde.....aeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
           qqD+qE+laflld+l+e+l++ k+kp+ e+++++   ++d+     a+e++  +n+s+i+d+F+g +ks+++c++c +vs++++pf++l
   Q: 348  QQDSQELLAFLLDGLHEDLNRVKKKPYLELKDAN--GRPDSvvakeAWENHRLRNDSIIVDIFHGLFKSTLVCPKCSKVSVTFDPFCYL 434
           *****************************98888..5555455777******************************************* PP
   S: 173  slpvpgkeetkke............................................................................ 185
           +lp+p k+++ +e                                                                            
   Q: 435  TLPLPLKRDRLLEvtlvpadpqrrpvqyrvvvpmmgaisdlceslsklsgvpaenmvvadvynhrfhkifqadeglnhimpkddifvye 523
           ********99888**************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 524  vckpsedgseyitfsvyfrekaarqssstsgtilfgqpllisvpkhkltvdhlygvvlerisryvklpvaeeystpcpgrgacngsssv 612
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 613  aegdieemehqddgqecreklaevdpchsegcmqieptrdvqpckkqhftfslvnlygtseinsivegkllklnafstlaidwdsdtrr 701
           ***************************************************************************************** PP
   S: 186  ...........................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksre 247
                                       l+dc+e ft+ e+l +++ +yc++ckk+q+a+kk++l++lP++L++hLkRfs+s++   r 
   Q: 702  llfdeqeaqafekhasvlqpqkmkavvALKDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPKILVVHLKRFSYSRY--WRD 788
           *******************************************************************************99885..556 PP
   S: 248  kinkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvkne.kgkWllfdDskVtevkeeevleetgstaYvlf 334
           k+++ vefp++ L++s+f+++p  +   ++ Y+Liav +H+G ++ GHY+ay+kn+ +gkW++fdDs+V+  +e+++++   + aYvlf
   Q: 789  KLDTVVEFPIRgLNMSEFVCDPRGS---SYVYDLIAVSNHYGAMGVGHYTAYAKNKvNGKWYYFDDSSVSLASEDQIVT---KAAYVLF 871
           *********************9987...7**************************62556*******************...******* PP
   S: 335  Ykrr 338
           Y+rr
   Q: 872  YQRR 875
           **96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 6    ksldgs.eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk...GkiL...eddktLadyglkdgstihllekksg 75
           +s+  s + ++ +++ d+Va+L ++i+k+++ip + ++rL+ +   G +    e ++tL d ++++g  +++++k+++
   Q: 100  ESSSPSnVISCCFSRRDSVATLVKEIRKLFKIPaEKDVRLWSShfdGSYEqlsELGVTLEDANIYHGELVLIEVKNED 177
           56666667788899*******************777*****555556664447***********99999999888876 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

WKRYVGYDRW DVSGVGDPNL FPGPIDNACL LNDGESQSLK EHLIAQLDYV LVPSSAWQKL 60
VSWYGCIEGQ QPIVRKVMEF GLYAKHCEVE VYPLELKLCE SSSPSNVISC CFSRRDSVAT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGAAGCGCT ACGTGGGTTA CGACAGGTGG GACGTGTCCG GCGTGGGCGA CCCCAACCTC 60
TTTCCTGGGC CCATCGACAA CGCGTGTCTG CTGAACGGTG AGTACGGCCC TGTGTGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0031397--P:negative regulation of protein ubiquitination
GO:0016579--P:protein deubiquitination
GO:0034394--P:protein localization to cell surface
GO:0031647--P:regulation of protein stability
GO:0000244--P:spliceosomal tri-snRNP complex assembly
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000058	Aegilops tauschii	40.92	2.00e-122	432.00
IUUC-Aml-001597	Ailuropoda melanoleuca	69.49	0.00e+00	1227.00
IUUC-Atr-002991	Amborella trichopoda	39.51	3.00e-120	426.00
IUUC-Apl-004068	Anas platyrhynchos	81.89	0.00e+00	1398.00
IUUC-Aca-004459	Anolis carolinensis	69.39	0.00e+00	1191.00
IUUC-Aly-006315	Arabidopsis lyrata	41.68	2.00e-131	462.00
IUUC-Ath-007343	Arabidopsis thaliana	38.04	2.00e-151	529.00
IUUC-Ago-007911	Ashbya gossypii	40.40	4.00e-67	249.00
IUUC-Afl-008507	Aspergillus flavus	39.56	1.00e-56	215.00
IUUC-Afu-008878	Aspergillus fumigatus	40.33	3.00e-57	217.00
IUUC-Ani-009479	Aspergillus nidulans	42.03	1.00e-52	201.00
IUUC-Ang-009562	Aspergillus niger	40.46	1.00e-57	219.00
IUUC-Aor-009949	Aspergillus oryzae	39.56	3.00e-56	213.00
IUUC-Ame-011064	Astyanax mexicanus	65.20	0.00e+00	904.00
IUUC-Bgr-012277	Blumeria graminis	44.60	2.00e-63	237.00
IUUC-Bta-012929	Bos taurus	71.21	0.00e+00	1239.00
IUUC-Bci-013993	Botrytis cinerea	43.58	2.00e-63	238.00
IUUC-Cja-018798	Callithrix jacchus	69.32	0.00e+00	1214.00
IUUC-Cfa-020599	Canis familiaris	71.16	0.00e+00	1243.00
IUUC-Cpo-022144	Cavia porcellus	69.57	0.00e+00	1231.00
IUUC-Csa-023770	Chlorocebus sabaeus	71.53	0.00e+00	1201.00
IUUC-Cho-024595	Choloepus hoffmanni	69.75	0.00e+00	852.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	43.75	2.00e-62	234.00
IUUC-Dre-027869	Danio rerio	60.81	0.00e+00	1092.00
IUUC-Dno-029316	Dasypus novemcinctus	70.50	0.00e+00	1231.00
IUUC-Dse-031432	Dothistroma septosporum	40.94	9.00e-59	222.00
IUUC-Ete-032970	Echinops telfairi	69.28	0.00e+00	847.00
IUUC-Eca-034012	Equus caballus	71.05	0.00e+00	1206.00
IUUC-Eeu-035158	Erinaceus europaeus	63.50	0.00e+00	667.00
IUUC-Fca-035373	Felis catus	66.74	0.00e+00	1208.00
IUUC-Fal-037634	Ficedula albicollis	84.44	0.00e+00	1451.00
IUUC-Fox-037986	Fusarium oxysporum	45.22	5.00e-66	246.00
IUUC-Fso-038291	Fusarium solani	46.32	8.00e-67	249.00
IUUC-Gmo-038866	Gadus morhua	60.35	0.00e+00	1013.00
IUUC-Ggr-039740	Gaeumannomyces graminis	44.32	4.00e-63	236.00
IUUC-Gga-040729	Gallus gallus	97.32	0.00e+00	1699.00
IUUC-Gac-042631	Gasterosteus aculeatus	62.87	0.00e+00	1092.00
IUUC-Ggo-045337	Gorilla gorilla	69.85	0.00e+00	1084.00
IUUC-Hsa-045669	Homo sapiens	71.51	0.00e+00	1231.00
IUUC-Hvu-047108	Hordeum vulgare	40.43	9.00e-125	440.00
IUUC-Itr-048610	Ictidomys tridecemlineatus	71.28	0.00e+00	1226.00
IUUC-Lch-050533	Latimeria chalumnae	63.51	0.00e+00	1038.00
IUUC-Loc-051800	Lepisosteus oculatus	59.07	0.00e+00	1145.00
IUUC-Laf-053803	Loxodonta africana	71.44	0.00e+00	1238.00
IUUC-Mcc-055556	Macaca mulatta	68.91	0.00e+00	1154.00
IUUC-Meu-056742	Macropus eugenii	70.46	0.00e+00	891.00
IUUC-Mor-056985	Magnaporthe oryzae	42.86	6.00e-61	229.00
IUUC-Mpo-057486	Magnaporthe poae	44.69	7.00e-63	236.00
IUUC-Mvi-060324	Microbotryum violaceum	47.58	4.00e-71	263.00
IUUC-Mdo-061848	Monodelphis domestica	72.18	0.00e+00	1240.00
IUUC-Mmu-063960	Mus musculus	70.46	0.00e+00	1218.00
IUUC-Mac-064956	Musa acuminata	37.04	7.00e-151	527.00
IUUC-Mpu-066920	Mustela putorius furo	70.12	0.00e+00	1239.00
IUUC-Mlu-068088	Myotis lucifugus	70.12	0.00e+00	1231.00
IUUC-Ncr-068879	Neurospora crassa	46.79	1.00e-63	238.00
IUUC-Nle-070010	Nomascus leucogenys	71.17	0.00e+00	1222.00
IUUC-Opr-070740	Ochotona princeps	73.40	0.00e+00	963.00
IUUC-Ont-072573	Oreochromis niloticus	61.21	0.00e+00	1102.00
IUUC-Oan-073363	Ornithorhynchus anatinus	67.48	0.00e+00	1174.00
IUUC-Ocu-074242	Oryctolagus cuniculus	67.26	0.00e+00	1130.00
IUUC-Oba-075553	Oryza barthii	40.31	2.00e-126	446.00
IUUC-Ogl-077583	Oryza glaberrima	40.31	2.00e-126	446.00
IUUC-Oin-079300	Oryza indica	40.46	1.00e-127	450.00
IUUC-Olo-080315	Oryza longistaminata	36.54	1.00e-147	516.00
IUUC-Oni-082834	Oryza nivara	34.50	2.00e-127	449.00
IUUC-Ola-086553	Oryzias latipes	61.89	0.00e+00	1140.00
IUUC-Olu-087717	Ostreococcus lucimarinus	41.04	4.00e-127	448.00
IUUC-Oga-088562	Otolemur garnettii	65.44	0.00e+00	1087.00
IUUC-Oar-090439	Ovis aries	71.09	0.00e+00	1233.00
IUUC-Ptr-090801	Pan troglodytes	71.59	0.00e+00	1232.00
IUUC-Pan-092717	Papio anubis	69.39	0.00e+00	1132.00
IUUC-Psi-093942	Pelodiscus sinensis	75.57	0.00e+00	1305.00
IUUC-Pfo-097060	Poecilia formosa	59.71	0.00e+00	1089.00
IUUC-Pab-098522	Pongo abelii	73.87	0.00e+00	968.00
IUUC-Pca-100161	Procavia capensis	69.22	0.00e+00	798.00
IUUC-Ppe-101587	Prunus persica	38.98	5.00e-150	525.00
IUUC-Ptt-103847	Puccinia triticina	36.53	9.00e-61	228.00
IUUC-Rno-106081	Rattus norvegicus	71.72	0.00e+00	1229.00
IUUC-Sha-106937	Sarcophilus harrisii	71.83	0.00e+00	1232.00
IUUC-Spo-108291	Schizosaccharomyces pombe	44.92	3.00e-77	283.00
IUUC-Sly-111746	Solanum lycopersicum	38.92	3.00e-151	529.00
IUUC-Stu-112671	Solanum tuberosum	38.50	5.00e-151	528.00
IUUC-Sar-113542	Sorex araneus	68.62	0.00e+00	1186.00
IUUC-Sre-115130	Sporisorium reilianum	33.03	6.00e-83	302.00
IUUC-Ssc-115637	Sus scrofa	70.75	0.00e+00	1228.00
IUUC-Tgu-117267	Taeniopygia guttata	81.09	0.00e+00	1419.00
IUUC-Tru-118634	Takifugu rubripes	63.01	0.00e+00	1076.00
IUUC-Tca-121598	Theobroma cacao	35.49	4.00e-122	431.00
IUUC-Tre-121888	Trichoderma reesei	43.38	2.00e-62	234.00
IUUC-Tvi-122422	Trichoderma virens	42.28	2.00e-59	224.00
IUUC-Tae-125295	Triticum aestivum	36.71	2.00e-147	515.00
IUUC-Tur-126392	Triticum urartu	37.60	2.00e-107	382.00
IUUC-Tbe-127669	Tupaia belangeri	59.97	0.00e+00	692.00
IUUC-Ttr-128778	Tursiops truncatus	70.07	0.00e+00	1213.00
IUUC-Uma-129498	Ustilago maydis	41.18	3.00e-71	263.00
IUUC-Vda-129781	Verticillium dahliae	44.12	3.00e-65	243.00
IUUC-Vvi-131010	Vitis vinifera	38.49	8.00e-152	530.00
IUUC-Xtr-132305	Xenopus tropicalis	62.31	0.00e+00	1128.00
IUUC-Zma-135699	Zea mays	37.20	3.00e-142	498.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence