iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
miRNAMap	RAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	2.60e-06	28.3	18	56
ULD/UDP/UFD/RAWUL	3.80e-28	98.2	135	228

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           Ca+C   f d + ++ C H f+++C+ ++        ++ +CP C
   Q: 18   CALCGGYFIDATTIVECLHSFCKTCIVRY------LETNKYCPMC 56
           ********999999***************......********** PP

ULD/UDP/UFD/RAWUL

   S: 5    Leplesnkakddsk............lkkkylrcsarltVkhlkkflaeklklsssyevdllcedevLednetLeeikyifiwkkegpL 81
           +e++e  ++++++k            +  ++lrc+a++tV+hl kfl++k++++s+y+v++l+ede+L++++tL++i+yi+ w+++gpL
   Q: 135  IEFYEGVRDREEKKslvengdgdkekTGVRFLRCPAAMTVMHLAKFLRNKMDVPSKYKVEILYEDEPLKEYYTLMDIAYIYPWRRNGPL 223
           555555555555555555555555559************************************************************** PP
   S: 82   vLqYr 86
           +L+Yr
   Q: 224  PLKYR 228
           ****9 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MHRTTRIKIT ELNPHLMCAL CGGYFIDATT IVECLHSFCK TCIVRYLETN KYCPMCDVQV 60
HKTRPLLSIR SDKTLQDIVY KLVPGLFKDE MKRRRDFYAA YPLTEVPNGS NEDRGEVLEQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGGAAAGAA ACGGGCTTTG GGCCCAGGGG GAAGCAGTGC AGGGAAGCAA CTAAGGGTGG 60
CTGGGTTTCT GACCCCATTT CTGTTTCCCA GGGTGACCCT TCTCAGGTCT CAGTCCTGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR032443--RAWUL
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF16207--RAWUL

SMART

SM00184--RING

Gene Ontology

GO:0016604--C:nuclear body
GO:0035102--C:PRC1 complex
GO:0001739--C:sex chromatin
GO:0003682--F:chromatin binding
GO:0008270--F:zinc ion binding
GO:0009952--P:anterior/posterior pattern specification
GO:0070301--P:cellular response to hydrogen peroxide
GO:0048704--P:embryonic skeletal system morphogenesis
GO:0016573--P:histone acetylation
GO:0001701--P:in utero embryonic development
GO:2001234--P:negative regulation of apoptotic signaling pathway
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter

KEGG

rno:287662

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002051	Ailuropoda melanoleuca	93.27	2.00e-153	535.00
IUUC-Aca-004230	Anolis carolinensis	75.28	4.00e-140	490.00
IUUC-Aly-005613	Arabidopsis lyrata	40.96	3.00e-12	66.20
IUUC-Bta-013298	Bos taurus	95.61	5.00e-161	560.00
IUUC-Bol-015090	Brassica oleracea	36.73	4.00e-13	69.30
IUUC-Cja-019674	Callithrix jacchus	95.91	1.00e-160	558.00
IUUC-Cfa-020865	Canis familiaris	89.31	3.00e-144	504.00
IUUC-Cpo-022149	Cavia porcellus	93.57	2.00e-158	551.00
IUUC-Csa-024153	Chlorocebus sabaeus	96.49	4.00e-161	560.00
IUUC-Dno-029941	Dasypus novemcinctus	93.57	3.00e-154	537.00
IUUC-Dor-030557	Dipodomys ordii	95.91	7.00e-161	559.00
IUUC-Eca-033878	Equus caballus	96.86	2.00e-151	527.00
IUUC-Eeu-035039	Erinaceus europaeus	90.64	1.00e-147	515.00
IUUC-Fca-036531	Felis catus	89.21	7.00e-140	489.00
IUUC-Gga-040311	Gallus gallus	83.71	5.00e-129	453.00
IUUC-Ggo-045132	Gorilla gorilla	96.20	4.00e-161	560.00
IUUC-Hsa-045703	Homo sapiens	95.91	8.00e-161	559.00
IUUC-Itr-048008	Ictidomys tridecemlineatus	97.08	2.00e-162	564.00
IUUC-Lch-050240	Latimeria chalumnae	73.47	2.00e-126	445.00
IUUC-Laf-053589	Loxodonta africana	96.21	4.00e-160	556.00
IUUC-Mcc-055228	Macaca mulatta	96.20	1.00e-159	555.00
IUUC-Meu-056268	Macropus eugenii	81.58	7.00e-132	463.00
IUUC-Mga-059555	Meleagris gallopavo	76.77	5.00e-82	296.00
IUUC-Mmr-060605	Microcebus murinus	96.20	6.00e-161	559.00
IUUC-Mdo-061947	Monodelphis domestica	82.08	6.00e-152	530.00
IUUC-Mmu-063845	Mus musculus	99.42	2.00e-165	574.00
IUUC-Mpu-066061	Mustela putorius furo	95.32	1.00e-160	558.00
IUUC-Mlu-067426	Myotis lucifugus	90.41	3.00e-142	497.00
IUUC-Nle-069772	Nomascus leucogenys	89.40	7.00e-154	536.00
IUUC-Ocu-074159	Oryctolagus cuniculus	82.05	2.00e-141	495.00
IUUC-Oga-088514	Otolemur garnettii	96.20	1.00e-161	562.00
IUUC-Oar-090406	Ovis aries	90.94	9.00e-161	559.00
IUUC-Ptr-091467	Pan troglodytes	95.91	1.00e-160	558.00
IUUC-Psi-093492	Pelodiscus sinensis	82.94	9.00e-150	522.00
IUUC-Pab-098045	Pongo abelii	90.14	2.00e-139	488.00
IUUC-Pca-100551	Procavia capensis	95.91	3.00e-161	560.00
IUUC-Pva-102686	Pteropus vampyrus	96.49	2.00e-161	561.00
IUUC-Sha-107443	Sarcophilus harrisii	73.04	1.00e-132	465.00
IUUC-Ssc-115591	Sus scrofa	77.68	3.00e-136	477.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence