iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	1.30e-14	54.6	24	90

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 1    aDvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           +D+ + v+g++f+ah+ vL asS +F+ l++++ +e+ +  + +++  +p+ f ++l+F+Y+gkl++
   Q: 24   CDCSILVEGKVFKAHRNVLFASSGYFKMLLSQNSKETSQPTTATFQTFSPDTFTVILDFVYSGKLSL 90
           8**********************************888788888889*****************986 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MEISSHQSHL LEQLNEQRRQ DVFCDCSILV EGKVFKAHRN VLFASSGYFK MLLSQNSKET 60
SQPTTATFQT FSPDTFTVIL DFVYSGKLSL TGQNVIEVMS AASFLQMTDV ISVCKTFIKS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGCGCCTTTT CCAACGTAAA GTACAATTTT AAATTTTAAG CTCCCCACTA AAAGAATGAT 60
CCGCAGCCAA CTGCTGGGGA ACCTGGGCGC CCCAGAGCCT GCGGAGGGTG CAGTCGGGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0238--DNA-binding
KW-1017--Isopeptide bond
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0832--Ubl conjugation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001850	Ailuropoda melanoleuca	78.83	0.00e+00	687.00
IUUC-Apl-003231	Anas platyrhynchos	70.38	2.00e-131	461.00
IUUC-Aca-004794	Anolis carolinensis	65.21	3.00e-147	514.00
IUUC-Ame-011665	Astyanax mexicanus	46.56	4.00e-93	335.00
IUUC-Bta-013057	Bos taurus	79.33	0.00e+00	735.00
IUUC-Cja-019989	Callithrix jacchus	86.17	0.00e+00	758.00
IUUC-Cfa-020866	Canis familiaris	86.39	0.00e+00	741.00
IUUC-Cpo-022548	Cavia porcellus	85.49	0.00e+00	701.00
IUUC-Csa-023375	Chlorocebus sabaeus	87.07	0.00e+00	769.00
IUUC-Cho-024440	Choloepus hoffmanni	80.43	0.00e+00	654.00
IUUC-Dre-027626	Danio rerio	45.41	8.00e-90	324.00
IUUC-Dno-030021	Dasypus novemcinctus	84.39	0.00e+00	718.00
IUUC-Dor-031116	Dipodomys ordii	79.82	0.00e+00	687.00
IUUC-Eca-033905	Equus caballus	86.39	0.00e+00	767.00
IUUC-Fca-036562	Felis catus	87.76	0.00e+00	795.00
IUUC-Fal-036662	Ficedula albicollis	67.98	2.00e-171	595.00
IUUC-Gmo-038907	Gadus morhua	69.92	1.00e-45	177.00
IUUC-Gga-040388	Gallus gallus	52.88	6.00e-127	447.00
IUUC-Gac-041383	Gasterosteus aculeatus	46.65	6.00e-94	337.00
IUUC-Ggo-045496	Gorilla gorilla	73.70	1.00e-175	608.00
IUUC-Hsa-046094	Homo sapiens	86.85	0.00e+00	770.00
IUUC-Itr-048286	Ictidomys tridecemlineatus	85.71	0.00e+00	756.00
IUUC-Lch-050008	Latimeria chalumnae	59.78	3.00e-138	484.00
IUUC-Loc-052392	Lepisosteus oculatus	49.54	6.00e-105	374.00
IUUC-Laf-053626	Loxodonta africana	86.17	0.00e+00	755.00
IUUC-Meu-056315	Macropus eugenii	77.43	0.00e+00	682.00
IUUC-Mga-059828	Meleagris gallopavo	68.81	0.00e+00	643.00
IUUC-Mmr-061265	Microcebus murinus	84.13	0.00e+00	737.00
IUUC-Mdo-062713	Monodelphis domestica	69.73	0.00e+00	649.00
IUUC-Mmu-063523	Mus musculus	89.80	0.00e+00	799.00
IUUC-Mpu-066095	Mustela putorius furo	86.39	0.00e+00	770.00
IUUC-Mlu-067305	Myotis lucifugus	85.94	0.00e+00	743.00
IUUC-Nle-069613	Nomascus leucogenys	86.62	0.00e+00	767.00
IUUC-Opr-070693	Ochotona princeps	82.81	0.00e+00	756.00
IUUC-Ont-071284	Oreochromis niloticus	49.15	1.00e-90	326.00
IUUC-Oan-073189	Ornithorhynchus anatinus	76.63	0.00e+00	668.00
IUUC-Ocu-074442	Oryctolagus cuniculus	85.03	0.00e+00	764.00
IUUC-Oga-088205	Otolemur garnettii	79.04	0.00e+00	764.00
IUUC-Oar-089255	Ovis aries	86.62	0.00e+00	771.00
IUUC-Ptr-090862	Pan troglodytes	86.85	0.00e+00	771.00
IUUC-Pan-092028	Papio anubis	86.62	0.00e+00	765.00
IUUC-Psi-093132	Pelodiscus sinensis	68.96	0.00e+00	654.00
IUUC-Pfo-096788	Poecilia formosa	47.61	4.00e-103	368.00
IUUC-Pab-098334	Pongo abelii	86.62	0.00e+00	760.00
IUUC-Pca-100730	Procavia capensis	78.00	0.00e+00	671.00
IUUC-Pva-103084	Pteropus vampyrus	86.39	0.00e+00	746.00
IUUC-Sha-107306	Sarcophilus harrisii	70.15	0.00e+00	661.00
IUUC-Ssc-115340	Sus scrofa	85.03	0.00e+00	760.00
IUUC-Tgu-117389	Taeniopygia guttata	73.59	2.00e-175	608.00
IUUC-Tru-118311	Takifugu rubripes	49.36	9.00e-84	303.00
IUUC-Tsy-119469	Tarsius syrichta	74.38	3.00e-175	607.00
IUUC-Tni-120508	Tetraodon nigroviridis	59.75	8.00e-51	194.00
IUUC-Ttr-129129	Tursiops truncatus	85.94	0.00e+00	761.00
IUUC-Vpa-130726	Vicugna pacos	84.57	6.00e-168	583.00
IUUC-Xtr-131889	Xenopus tropicalis	49.04	2.00e-109	389.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence