iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mdo-061985

Ensembl Protein ID

ENSMODP00000021684.3

UniProt Accession

F6VID8; F6VID8_MONDO

Protein Name

Uncharacterized protein

Gene Name

RNF19B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMODG00000017373.3	ENSMODT00000022062.3	ENSMODP00000021684.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	4.30e-53	180.8	119	318

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++Cl++l++e+++ ll+C h+ C++Cl++yl+l+i+e++ + +scp  ec+e+l++++i+ ll+++ l+++ye+++l++++++d++++w
   Q: 119  CPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISESR-VPVSCP--ECSERLNPHDIRLLLADPPLMHKYEEFMLRRYLASDPDCRW 205
           ****************************************.99****..89*************************************** PP
   S: 91   cpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeek......eeaeskelleanskkCpkCkvyie 172
           cpapdC ++v++  +a  +kl++e+e+c++efC++Ck++wH++++C+++++++a+t + +       ++ +++  ++++k+Cp+C++yi+
   Q: 206  CPAPDCGYAVIAYGCAscPKLTCEREGCQTEFCYHCKQIWHPNQTCDMARQQRAQTLRVRtkhtsgLSYGQESGPADDIKPCPRCSAYII 295
           *************999899************************************99988888888888899999*************** PP
   S: 173  k..negCnhmtCakCkaefCwlC 193
           k  +++CnhmtCa C++efCwlC
   Q: 296  KmnDGSCNHMTCAVCGCEFCWLC 318
           997889***************** PP

Organism

Monodelphis domestica

Protein Sequence
(Fasta)

MGSEKDSESP RSTSLPAATP DPKCRGGGGR RHRFLSSLVL LPAGRSRRAR AKPPPPALAP 60
APAPAEPPAP PPPPPPPPAP PEAPPAEPAP EAEVAVAAAA TVAAAGEEGP GPGGDEVECP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGCTCCG AGAAGGACTC CGAGTCTCCT CGCTCTACGT CCCTGCCCGC GGCCACACCG 60
GACCCCAAGT GCCGAGGGGG CGGCGGGCGG CGACACCGCT TCCTCTCCAG CCTCGTTCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0044194--C:cytolytic granule
GO:0005829--C:cytosol
GO:0016021--C:integral component of membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

KEGG

mdo:100032415

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002183	Ailuropoda melanoleuca	90.72	0.00e+00	1025.00
IUUC-Apl-003468	Anas platyrhynchos	92.68	0.00e+00	874.00
IUUC-Aca-004324	Anolis carolinensis	88.42	0.00e+00	989.00
IUUC-Ame-011813	Astyanax mexicanus	65.59	0.00e+00	690.00
IUUC-Bta-013135	Bos taurus	92.62	0.00e+00	1080.00
IUUC-Cja-019264	Callithrix jacchus	83.79	0.00e+00	939.00
IUUC-Cpo-022502	Cavia porcellus	91.11	0.00e+00	921.00
IUUC-Cho-025032	Choloepus hoffmanni	72.60	0.00e+00	701.00
IUUC-Dre-028769	Danio rerio	67.92	0.00e+00	737.00
IUUC-Dor-030551	Dipodomys ordii	96.98	5.00e-119	421.00
IUUC-Ete-033008	Echinops telfairi	78.48	0.00e+00	757.00
IUUC-Eca-033267	Equus caballus	92.40	0.00e+00	880.00
IUUC-Fca-035520	Felis catus	92.03	0.00e+00	880.00
IUUC-Fal-037090	Ficedula albicollis	91.36	0.00e+00	787.00
IUUC-Gga-041229	Gallus gallus	88.82	0.00e+00	761.00
IUUC-Gac-041619	Gasterosteus aculeatus	70.12	0.00e+00	736.00
IUUC-Hsa-045958	Homo sapiens	93.23	0.00e+00	1083.00
IUUC-Itr-048425	Ictidomys tridecemlineatus	91.79	0.00e+00	932.00
IUUC-Lch-049552	Latimeria chalumnae	85.00	0.00e+00	919.00
IUUC-Loc-051738	Lepisosteus oculatus	67.83	0.00e+00	779.00
IUUC-Laf-054252	Loxodonta africana	87.64	0.00e+00	891.00
IUUC-Meu-055920	Macropus eugenii	97.99	0.00e+00	1001.00
IUUC-Mga-059587	Meleagris gallopavo	88.56	0.00e+00	815.00
IUUC-Mmu-064262	Mus musculus	91.61	0.00e+00	1065.00
IUUC-Mpu-066101	Mustela putorius furo	92.31	0.00e+00	1072.00
IUUC-Mlu-067347	Myotis lucifugus	91.59	0.00e+00	882.00
IUUC-Ont-071298	Oreochromis niloticus	69.24	0.00e+00	755.00
IUUC-Oan-073219	Ornithorhynchus anatinus	89.89	0.00e+00	879.00
IUUC-Ocu-073792	Oryctolagus cuniculus	89.81	0.00e+00	841.00
IUUC-Ola-086499	Oryzias latipes	70.30	0.00e+00	761.00
IUUC-Oga-088812	Otolemur garnettii	93.57	0.00e+00	1029.00
IUUC-Oar-090353	Ovis aries	91.67	0.00e+00	946.00
IUUC-Psi-092988	Pelodiscus sinensis	93.05	0.00e+00	873.00
IUUC-Pfo-096268	Poecilia formosa	67.33	0.00e+00	758.00
IUUC-Pca-100597	Procavia capensis	91.60	0.00e+00	874.00
IUUC-Pva-102542	Pteropus vampyrus	79.53	0.00e+00	829.00
IUUC-Sha-106512	Sarcophilus harrisii	97.57	0.00e+00	1113.00
IUUC-Sar-113233	Sorex araneus	90.30	0.00e+00	841.00
IUUC-Ssc-115781	Sus scrofa	92.73	0.00e+00	1129.00
IUUC-Tgu-117384	Taeniopygia guttata	96.14	0.00e+00	777.00
IUUC-Tru-117919	Takifugu rubripes	68.89	0.00e+00	739.00
IUUC-Tsy-119275	Tarsius syrichta	90.11	0.00e+00	863.00
IUUC-Tbe-127335	Tupaia belangeri	98.64	0.00e+00	664.00
IUUC-Ttr-128554	Tursiops truncatus	91.62	0.00e+00	873.00
IUUC-Vpa-130407	Vicugna pacos	85.61	0.00e+00	880.00
IUUC-Xtr-132325	Xenopus tropicalis	85.19	0.00e+00	730.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence