iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000005297.2	ENSLACT00000006019.1	ENSLACP00000005967.1
ENSLACG00000005297.2	ENSLACT00000006020.2	ENSLACP00000005968.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	4.00e-93	312.5	160	503

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgyeqq 90
           Gl NlgNtC+mN+++Q+L+++p lr+++l+ +++k++ +   +p+ +l++++ +lf+e+++++++   p +ll+ +++ a+++ gyeqq
   Q: 160  GLINLGNTCFMNCIVQALTHTPLLRDFFLS-DRHKCEMQ---SPNSCLVCEMSTLFQEFYSGHRSPHIPYRLLHLVWTHARHLAGYEQQ 244
           9*****************************.99999975...78********************************************* PP
   S: 91   DaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgk 179
           Da+Efl   ld l++++k                  ++ ++ +++++ +++i+++F g l+s+++c+ c+ vs++ +pf+d+sl++pg+
   Q: 245  DAHEFLIAALDVLHRHCKG----------------DDNGKKANNPNHCNCIIDQIFTGGLQSDVTCQVCQGVSTTIDPFWDISLDLPGS 317
           *****************22................22335677899999**************************************** PP
   S: 180  eetkke....................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrek 248
           ++   +                    +l+dcL+ ft++e+l ++ k++c+ c+++qe++k+l++kklP v ++hLkRf  +++ k r+k
   Q: 318  STPFWPlspgsdgsvmngeshmsgttTLTDCLRRFTRPEHLGSSAKIKCSGCHSYQESTKQLTMKKLPIVACFHLKRF--EHSAKLRRK 404
           *87777************************************************************************..5666899** PP
   S: 249  inkkvefpleLdlspfctspeekqke............kkkYeLiavvvHsGslssGHYvayvknekgkWllfdDskVtevkeeevlee 325
           i+++v+fpleLd++pf++s++e+  +            ++kY+L+avv+H+G+l+sGHY+++++++k++W+++dD  +t+ + ++vl  
   Q: 405  ITTYVSFPLELDMTPFMASSKESRMNgqyqqpadslnnDNKYSLFAVVNHQGTLESGHYTSFIRQHKDQWFKCDDAIITKASIKDVLD- 492
           *******************5555444666666666666**************************************************. PP
   S: 326  tgstaYvlfYkrr 338
             s++Y+lfY+++
   Q: 493  --SEGYLLFYHKQ 503
           ..********985 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MSPAGCSHVN SFKVENWKQN LRVIYQCFVW SGTPETRKRK AKSCICHMCG AHLSRLHSCL 60
YCVFFGCFTK KHIHEHAKTK RHNLAIDLLY GGIYCFMCQD YIYDKDMEQI AKEEQRKAWK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGGGTGAA GAGGGGGGAT GCGAGGCGTG GCCTAGCGCG AGAGCGACGG CTATGTTCCG 60
ACCAGTGAGC GCGCAGCTCT CGCACACAGG GGCCAATTGC AGCAGAGTTT GGGGGTTCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

lcm:102356785

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000393	Aegilops tauschii	37.29	6.00e-64	239.00
IUUC-Aml-001343	Ailuropoda melanoleuca	92.32	0.00e+00	1009.00
IUUC-Atr-002653	Amborella trichopoda	37.62	1.00e-99	357.00
IUUC-Apl-003433	Anas platyrhynchos	94.83	0.00e+00	962.00
IUUC-Aca-005347	Anolis carolinensis	90.93	0.00e+00	1018.00
IUUC-Aly-006565	Arabidopsis lyrata	36.28	5.00e-71	261.00
IUUC-Ath-007536	Arabidopsis thaliana	36.50	2.00e-71	263.00
IUUC-Ago-007811	Ashbya gossypii	30.77	9.00e-53	201.00
IUUC-Acl-008124	Aspergillus clavatus	32.06	3.00e-59	222.00
IUUC-Afl-008464	Aspergillus flavus	33.73	3.00e-55	209.00
IUUC-Afu-008912	Aspergillus fumigatus	31.63	3.00e-57	216.00
IUUC-Ani-009168	Aspergillus nidulans	32.33	2.00e-58	219.00
IUUC-Ang-009694	Aspergillus niger	31.25	5.00e-56	211.00
IUUC-Aor-010035	Aspergillus oryzae	35.58	2.00e-38	152.00
IUUC-Ate-010382	Aspergillus terreus	32.53	1.00e-53	203.00
IUUC-Ame-011253	Astyanax mexicanus	87.47	0.00e+00	851.00
IUUC-Bgr-012150	Blumeria graminis	30.84	4.00e-48	185.00
IUUC-Bta-013303	Bos taurus	92.72	0.00e+00	1013.00
IUUC-Bci-013604	Botrytis cinerea	32.53	9.00e-57	214.00
IUUC-Bdi-014171	Brachypodium distachyon	35.42	5.00e-77	281.00
IUUC-Bol-016509	Brassica oleracea	37.39	4.00e-73	269.00
IUUC-Bra-016962	Brassica rapa	36.29	4.00e-72	265.00
IUUC-Cja-019283	Callithrix jacchus	95.75	0.00e+00	866.00
IUUC-Cfa-021239	Canis familiaris	94.27	0.00e+00	951.00
IUUC-Cpo-022354	Cavia porcellus	93.50	0.00e+00	1015.00
IUUC-Csa-023145	Chlorocebus sabaeus	93.90	0.00e+00	1023.00
IUUC-Cho-024938	Choloepus hoffmanni	90.52	2.00e-63	236.00
IUUC-Cin-025109	Ciona intestinalis	57.56	2.00e-122	432.00
IUUC-Csv-026214	Ciona savignyi	55.85	2.00e-175	608.00
IUUC-Cgl-026457	Colletotrichum gloeosporioides	30.48	4.00e-56	212.00
IUUC-Cne-027085	Cryptococcus neoformans	32.83	7.00e-65	241.00
IUUC-Dre-027433	Danio rerio	95.51	0.00e+00	939.00
IUUC-Dno-030095	Dasypus novemcinctus	95.31	0.00e+00	956.00
IUUC-Dor-030832	Dipodomys ordii	85.57	3.00e-97	348.00
IUUC-Dse-031415	Dothistroma septosporum	30.56	4.00e-62	232.00
IUUC-Dme-032074	Drosophila melanogaster	51.80	1.00e-140	493.00
IUUC-Ete-033175	Echinops telfairi	74.77	0.00e+00	682.00
IUUC-Eca-033736	Equus caballus	94.24	0.00e+00	945.00
IUUC-Eeu-034814	Erinaceus europaeus	97.14	3.00e-121	428.00
IUUC-Fca-035861	Felis catus	94.67	0.00e+00	950.00
IUUC-Fal-037645	Ficedula albicollis	94.96	0.00e+00	947.00
IUUC-Fox-038046	Fusarium oxysporum	32.52	1.00e-55	210.00
IUUC-Fso-038321	Fusarium solani	32.27	3.00e-55	209.00
IUUC-Gmo-038474	Gadus morhua	94.93	1.00e-172	598.00
IUUC-Ggr-040044	Gaeumannomyces graminis	31.47	2.00e-55	209.00
IUUC-Gga-040624	Gallus gallus	93.90	0.00e+00	1030.00
IUUC-Gac-042197	Gasterosteus aculeatus	88.80	0.00e+00	952.00
IUUC-Gma-043933	Glycine max	36.24	5.00e-89	321.00
IUUC-Ggo-044409	Gorilla gorilla	94.09	0.00e+00	1024.00
IUUC-Hsa-046521	Homo sapiens	94.09	0.00e+00	1024.00
IUUC-Hvu-047739	Hordeum vulgare	38.67	3.00e-69	255.00
IUUC-Itr-048375	Ictidomys tridecemlineatus	93.31	0.00e+00	1017.00
IUUC-Kpa-049135	Komagataella pastoris	35.78	2.00e-69	256.00
IUUC-Lpe-050969	Leersia perrieri	38.46	2.00e-72	266.00
IUUC-Loc-052765	Lepisosteus oculatus	86.44	0.00e+00	929.00
IUUC-Lma-053105	Leptosphaeria maculans	34.53	5.00e-65	241.00
IUUC-Laf-053571	Loxodonta africana	95.52	0.00e+00	955.00
IUUC-Mcc-055166	Macaca mulatta	93.90	0.00e+00	1023.00
IUUC-Mor-057103	Magnaporthe oryzae	30.25	1.00e-57	217.00
IUUC-Mpo-057621	Magnaporthe poae	31.52	1.00e-55	210.00
IUUC-Mtr-057894	Medicago truncatula	37.38	5.00e-87	315.00
IUUC-Mla-059185	Melampsora laricipopulina	30.02	3.00e-42	166.00
IUUC-Mga-059709	Meleagris gallopavo	94.83	0.00e+00	962.00
IUUC-Mvi-060530	Microbotryum violaceum	34.63	7.00e-60	224.00
IUUC-Mmr-060988	Microcebus murinus	93.70	0.00e+00	1022.00
IUUC-Mdo-063065	Monodelphis domestica	98.03	0.00e+00	1056.00
IUUC-Mmu-063829	Mus musculus	93.70	0.00e+00	1019.00
IUUC-Mac-065419	Musa acuminata	39.84	6.00e-72	265.00
IUUC-Mpu-066687	Mustela putorius furo	93.11	0.00e+00	1010.00
IUUC-Mlu-067330	Myotis lucifugus	82.88	0.00e+00	892.00
IUUC-Nfi-068423	Neosartorya fischeri	31.86	2.00e-57	216.00
IUUC-Ncr-068809	Neurospora crassa	31.09	3.00e-57	216.00
IUUC-Nle-069261	Nomascus leucogenys	89.96	0.00e+00	969.00
IUUC-Opr-070469	Ochotona princeps	77.78	0.00e+00	676.00
IUUC-Ont-071961	Oreochromis niloticus	92.72	0.00e+00	994.00
IUUC-Oan-073565	Ornithorhynchus anatinus	87.91	0.00e+00	931.00
IUUC-Ocu-074435	Oryctolagus cuniculus	93.74	0.00e+00	992.00
IUUC-Oba-075688	Oryza barthii	36.20	7.00e-76	278.00
IUUC-Obr-076652	Oryza brachyantha	41.42	4.00e-74	271.00
IUUC-Ogl-077910	Oryza glaberrima	35.93	7.00e-79	288.00
IUUC-Ogu-078479	Oryza glumaepatula	35.93	6.00e-79	288.00
IUUC-Oin-079697	Oryza indica	39.41	2.00e-75	276.00
IUUC-Olo-080811	Oryza longistaminata	41.38	4.00e-53	201.00
IUUC-Ome-081706	Oryza meridionalis	35.93	3.00e-78	286.00
IUUC-Oni-083070	Oryza nivara	35.53	9.00e-79	287.00
IUUC-Opu-083605	Oryza punctata	39.89	3.00e-67	248.00
IUUC-Oru-084522	Oryza rufipogon	35.93	7.00e-79	288.00
IUUC-Osa-085351	Oryza sativa	39.46	3.00e-76	279.00
IUUC-Ola-086743	Oryzias latipes	88.31	0.00e+00	757.00
IUUC-Olu-087695	Ostreococcus lucimarinus	31.27	2.00e-50	192.00
IUUC-Oga-089131	Otolemur garnettii	90.65	0.00e+00	1008.00
IUUC-Oar-089319	Ovis aries	94.44	0.00e+00	944.00
IUUC-Ptr-090783	Pan troglodytes	95.52	0.00e+00	957.00
IUUC-Pan-092927	Papio anubis	94.09	0.00e+00	1025.00
IUUC-Psi-093670	Pelodiscus sinensis	93.89	0.00e+00	963.00
IUUC-Pma-094323	Petromyzon marinus	70.12	0.00e+00	723.00
IUUC-Pno-095141	Phaeosphaeria nodorum	31.96	5.00e-57	215.00
IUUC-Ppa-095413	Physcomitrella patens	34.45	4.00e-80	291.00
IUUC-Pfo-096462	Poecilia formosa	92.16	0.00e+00	1009.00
IUUC-Pab-097612	Pongo abelii	94.09	0.00e+00	1024.00
IUUC-Pop-099558	Populus trichocarpa	34.62	4.00e-87	315.00
IUUC-Pca-100329	Procavia capensis	82.68	0.00e+00	893.00
IUUC-Ppe-102020	Prunus persica	36.16	7.00e-93	334.00
IUUC-Pva-102721	Pteropus vampyrus	78.79	0.00e+00	834.00
IUUC-Pgr-103657	Puccinia graminis	26.77	4.00e-38	152.00
IUUC-Pte-104340	Pyrenophora teres	31.74	4.00e-58	218.00
IUUC-Pyt-104782	Pyrenophora triticirepentis	36.71	7.00e-66	244.00
IUUC-Rno-105247	Rattus norvegicus	93.70	0.00e+00	1020.00
IUUC-Sce-106247	Saccharomyces cerevisiae	31.60	2.00e-52	199.00
IUUC-Sha-107538	Sarcophilus harrisii	95.85	1.00e-124	437.00
IUUC-Sja-107656	Schizosaccharomyces japonicus	34.70	1.00e-67	250.00
IUUC-Spo-108226	Schizosaccharomyces pombe	32.29	3.00e-61	229.00
IUUC-Ssl-108531	Sclerotinia sclerotiorum	32.35	4.00e-54	205.00
IUUC-Smo-109310	Selaginella moellendorffii	35.77	9.00e-88	317.00
IUUC-Sit-109716	Setaria italica	35.87	3.00e-80	292.00
IUUC-Sly-111077	Solanum lycopersicum	37.43	7.00e-83	301.00
IUUC-Stu-112203	Solanum tuberosum	39.86	2.00e-75	276.00
IUUC-Sar-113174	Sorex araneus	78.48	0.00e+00	800.00
IUUC-Sbi-114205	Sorghum bicolor	35.59	1.00e-81	297.00
IUUC-Sre-115195	Sporisorium reilianum	33.84	3.00e-30	127.00
IUUC-Ssc-115315	Sus scrofa	81.68	0.00e+00	897.00
IUUC-Tgu-116938	Taeniopygia guttata	97.87	0.00e+00	972.00
IUUC-Tru-117622	Takifugu rubripes	91.78	0.00e+00	1011.00
IUUC-Tsy-119431	Tarsius syrichta	82.69	0.00e+00	798.00
IUUC-Tni-120119	Tetraodon nigroviridis	94.11	0.00e+00	1015.00
IUUC-Tca-121154	Theobroma cacao	36.95	5.00e-90	324.00
IUUC-Tre-122139	Trichoderma reesei	31.66	2.00e-54	206.00
IUUC-Tvi-122599	Trichoderma virens	31.33	5.00e-56	211.00
IUUC-Tae-125608	Triticum aestivum	34.00	1.00e-86	313.00
IUUC-Tme-127115	Tuber melanosporum	37.13	2.00e-82	299.00
IUUC-Ttr-129006	Tursiops truncatus	83.33	0.00e+00	881.00
IUUC-Uma-129455	Ustilago maydis	32.53	1.00e-34	141.00
IUUC-Vda-129829	Verticillium dahliae	33.22	2.00e-35	142.00
IUUC-Vvi-131477	Vitis vinifera	35.58	2.00e-78	286.00
IUUC-Xtr-132444	Xenopus tropicalis	94.46	0.00e+00	1038.00
IUUC-Xma-133514	Xiphophorus maculatus	94.88	0.00e+00	1023.00
IUUC-Yli-134357	Yarrowia lipolytica	28.11	4.00e-49	189.00
IUUC-Zma-134945	Zea mays	35.00	4.00e-77	281.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence