iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Nle-069565

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ADFV01109101

Gene Name

HECTD3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSNLEG00000014243.1	ENSNLET00000018190.1	ENSNLEP00000017324.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	2.00e-62	211.5	527	800

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/HECT

   S: 8    rlevefvgEegldlgGvtreflallskelqnpd......lglflysendketlqpnpdsglknp..ehlklFeflGrllgkalqdgrll 88
            +e++f  E  +d+gG +r+ la +s+el+ ++      l++f++++n+ + +  ++d+++ np  + +  +e++G+l+g al+ +++l
   Q: 527  WWECKFIAEGIIDQGGGFRDSLADMSEELCPSSadtpvpLPFFVRTANQGNGTGEARDMYVPNPscRDFAKYEWIGQLMGAALRGKEFL 615
           355*****************************9999*99**********************9999999********************* PP
   S: 89   dlplsksfyklllgkklsl.edleevdpelykslkeikenaesdieelgldltfsvseei...lgetkeeeLkpgGenipVtneNkeeY 173
            l l+ +++k+l g+++s+ +d+++vd+ l+k l+ ++      +++++++++f ++ +    l++++++eL+pgG+ i V + +++++
   Q: 616  VLALPGFVWKQLSGEEVSWsKDFPAVDSVLVKLLEVMEG-----MDKETFEFKFGKELTFttvLSDQQVVELIPGGAGIVVGYGDRSRF 699
           **************************************5.....56666777777443334449************************* PP
   S: 174  vklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefsseerk 262
           ++lv ++rl+e  keqv+a+++G+ +v+p+ +l+l+t++ele  +cG++e++v++l+k t++++ ++++++ +q+Fwe+l++f++e+r+
   Q: 700  IQLVQKARLEE-SKEQVAAMQAGLLKVVPQAVLDLLTWQELEKKVCGDPEVTVDALRKLTRFED-FEPSDSRVQYFWEALNNFTNEDRS 786
           **********9.9*************************************************76.************************ PP
   S: 263  afLqFvTgssrlPl 276
           +fL+FvTg+srlP+
   Q: 787  RFLRFVTGRSRLPA 800
           *************7 PP

Organism

Nomascus leucogenys

Protein Sequence
(Fasta)

MAGPGPGAVL ESPRQLLGRV RFLAEAARSL RAGRPLPAAL AFVPREVLYK LYKDPAGPSR 60
VLLPVWEAEG LGLRVGAAGP APGTGSGPLR AARDSIELRR GACVRTTGEE LCNGHGLWVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGGCGTGGT GGGAAGCTCT GTCGGCTGTC GAGCCAGCCG GGCAGGGTCG CCCCTAGGCG 60
CTCACCTCCC CCACTTCGCC ATGGCGGGTC CTGGCCCGGG CGCGGTGCTG GAGTCCCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR004939--APC_su10/DOC_dom
IPR008979--Galactose-bd-like
IPR000569--HECT_dom

PROSITE

PS51284--DOC
PS50237--HECT

Pfam

PF03256--ANAPC10
PF00632--HECT

SMART

SM01337--APC10
SM00119--HECTc

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001229	Ailuropoda melanoleuca	97.78	0.00e+00	1565.00
IUUC-Apl-003715	Anas platyrhynchos	84.59	0.00e+00	1217.00
IUUC-Aca-004377	Anolis carolinensis	77.94	0.00e+00	1284.00
IUUC-Ame-011918	Astyanax mexicanus	62.79	0.00e+00	1024.00
IUUC-Bta-012736	Bos taurus	98.52	0.00e+00	1584.00
IUUC-Cja-019926	Callithrix jacchus	98.64	0.00e+00	1576.00
IUUC-Cfa-020753	Canis familiaris	98.67	0.00e+00	1067.00
IUUC-Cpo-021415	Cavia porcellus	97.28	0.00e+00	1558.00
IUUC-Csa-023096	Chlorocebus sabaeus	99.75	0.00e+00	1590.00
IUUC-Dre-028746	Danio rerio	68.08	0.00e+00	1103.00
IUUC-Dno-029293	Dasypus novemcinctus	97.92	0.00e+00	966.00
IUUC-Dor-031113	Dipodomys ordii	98.56	0.00e+00	1133.00
IUUC-Ete-032601	Echinops telfairi	88.96	0.00e+00	1317.00
IUUC-Eca-034198	Equus caballus	95.56	0.00e+00	1532.00
IUUC-Eeu-034708	Erinaceus europaeus	97.48	0.00e+00	797.00
IUUC-Fca-035478	Felis catus	98.45	0.00e+00	1546.00
IUUC-Fal-037366	Ficedula albicollis	75.90	0.00e+00	1242.00
IUUC-Gmo-039020	Gadus morhua	74.21	0.00e+00	949.00
IUUC-Gga-040332	Gallus gallus	78.80	0.00e+00	1305.00
IUUC-Gac-042336	Gasterosteus aculeatus	68.57	0.00e+00	1146.00
IUUC-Ggo-045382	Gorilla gorilla	100.00	0.00e+00	1594.00
IUUC-Hsa-046562	Homo sapiens	100.00	0.00e+00	1594.00
IUUC-Itr-048208	Ictidomys tridecemlineatus	98.27	0.00e+00	1573.00
IUUC-Lch-049606	Latimeria chalumnae	65.37	0.00e+00	838.00
IUUC-Loc-052448	Lepisosteus oculatus	62.86	0.00e+00	1013.00
IUUC-Laf-054507	Loxodonta africana	97.28	0.00e+00	1593.00
IUUC-Mcc-055690	Macaca mulatta	99.75	0.00e+00	1592.00
IUUC-Meu-055970	Macropus eugenii	84.44	0.00e+00	1338.00
IUUC-Mga-059654	Meleagris gallopavo	84.81	0.00e+00	1203.00
IUUC-Mmr-061069	Microcebus murinus	98.77	0.00e+00	1577.00
IUUC-Mdo-062547	Monodelphis domestica	91.67	0.00e+00	690.00
IUUC-Mmu-063096	Mus musculus	97.65	0.00e+00	1566.00
IUUC-Mpu-065846	Mustela putorius furo	97.90	0.00e+00	1578.00
IUUC-Mlu-067992	Myotis lucifugus	97.24	0.00e+00	1468.00
IUUC-Opr-070853	Ochotona princeps	89.95	0.00e+00	1009.00
IUUC-Ont-071628	Oreochromis niloticus	68.03	0.00e+00	1113.00
IUUC-Ocu-074094	Oryctolagus cuniculus	98.64	0.00e+00	1576.00
IUUC-Ola-087384	Oryzias latipes	68.31	0.00e+00	1162.00
IUUC-Oga-088224	Otolemur garnettii	98.14	0.00e+00	1572.00
IUUC-Oar-090043	Ovis aries	91.98	0.00e+00	1465.00
IUUC-Ptr-090852	Pan troglodytes	99.75	0.00e+00	1585.00
IUUC-Pan-092787	Papio anubis	99.75	0.00e+00	1592.00
IUUC-Psi-092986	Pelodiscus sinensis	73.97	0.00e+00	887.00
IUUC-Pma-094416	Petromyzon marinus	39.78	1.00e-158	553.00
IUUC-Pfo-096720	Poecilia formosa	68.36	0.00e+00	1156.00
IUUC-Pab-098325	Pongo abelii	99.40	0.00e+00	1307.00
IUUC-Pca-100885	Procavia capensis	82.64	0.00e+00	1107.00
IUUC-Pva-102829	Pteropus vampyrus	86.36	0.00e+00	1056.00
IUUC-Rno-104882	Rattus norvegicus	97.90	0.00e+00	1565.00
IUUC-Sha-106811	Sarcophilus harrisii	91.04	8.00e-116	410.00
IUUC-Sar-113020	Sorex araneus	82.16	3.00e-175	608.00
IUUC-Ssc-115436	Sus scrofa	98.52	1.00e-158	552.00
IUUC-Tgu-117042	Taeniopygia guttata	78.48	0.00e+00	1294.00
IUUC-Tru-118419	Takifugu rubripes	66.01	0.00e+00	1077.00
IUUC-Tsy-118829	Tarsius syrichta	97.73	0.00e+00	989.00
IUUC-Tni-120410	Tetraodon nigroviridis	54.68	0.00e+00	831.00
IUUC-Tbe-128113	Tupaia belangeri	98.65	0.00e+00	753.00
IUUC-Ttr-128167	Tursiops truncatus	97.17	0.00e+00	1522.00
IUUC-Xtr-132910	Xenopus tropicalis	64.04	0.00e+00	1018.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence