iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

UUCD2 ID

IUUC-Hsa-046264

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AC024221

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSG00000248710.1	ENST00000483754.1	ENSP00000456272.1

Annotation

Cancer Mutation
ICGC
mRNA Expression
ArrayExpress
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.90e-08	36.3	10	60
E3 adaptor/Cullin RING/DCX/DWD	6.50e-06	28.0	399	427

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefr..........CPlCr 46
           C+iC++ f+d p+vlpC H+f+++Cl+++     ++s++f+          CP Cr
   Q: 10   CPICYSIFED-PRVLPCSHTFCRNCLENI----LQASGNFYiwrplriplkCPNCR 60
           **********.***************999....567777766666666777****8 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWD 29
           H+ ++t++a+ +d  l+++Gs  +t++++D
   Q: 399  HEHPITSVAWaPDgELFAVGS-FHTLRLCD 427
           99*********9978888887.689*9999 PP

Organism

Homo sapiens

Protein Sequence
(Fasta)

MHNFEEELTC PICYSIFEDP RVLPCSHTFC RNCLENILQA SGNFYIWRPL RIPLKCPNCR 60
SITEIAPTGI ESLPVNFALR AIIEKYQQED HPDIVTCPEH YRQPLNVYCL LDKKLVCGHC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCCCTTCGG GGCAGAGGAG GGCGGGGACT CGGGGCGGCT CTCAGCATCC GCCTGGAGCT 60
CGTGGCGCTG TGTTTCCGTG CTGTGGAGTT GCCTGGTCCG CTTCCTCCCC GCGGTGAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0853--WD repeat
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
IPR027370--Znf-RING_LisH
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
PS50119--ZF_BBOX
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00643--zf-B_box
PF13445--zf-RING_UBOX

SMART

SM00184--RING
SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0005929--C:cilium
GO:0030992--C:intraciliary transport particle B
GO:0008270--F:zinc ion binding
GO:0060271--P:cilium assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Cja-019076	Callithrix jacchus	95.25	0.00e+00	1862.00
IUUC-Ete-033028	Echinops telfairi	75.53	0.00e+00	1434.00
IUUC-Gmo-038657	Gadus morhua	56.41	0.00e+00	1058.00
IUUC-Gac-041586	Gasterosteus aculeatus	64.03	0.00e+00	1342.00
IUUC-Loc-052774	Lepisosteus oculatus	69.59	0.00e+00	1416.00
IUUC-Mdo-062850	Monodelphis domestica	85.47	0.00e+00	1651.00
IUUC-Ocu-073896	Oryctolagus cuniculus	92.61	0.00e+00	1790.00
IUUC-Ola-086767	Oryzias latipes	61.60	0.00e+00	1245.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence