iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092728

Ensembl Protein ID

ENSPANP00000004294.1

UniProt Accession

A0A096MWN6; A0A096MWN6_PAPAN

Genbank Protein ID

ENSPANP00000004294

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01022254

Gene Name

UBE3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000006126.1	ENSPANT00000013363.1	ENSPANP00000004294.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/HECT	1.70e-111	372.9	703	1069

Active Site

Position(s)	Description	Evidence
1037	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 activity/HECT

   S: 2    ksdlkkrlevefvg.....EegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknpehlklFeflGrllgkalq 83
           ++++k +++v+fv+     E+g+d++Gv++efl++++k++++p l+lf+++++d++ l+p+p+s++++ ++l+lFef+G++lgka++
   Q: 703  QHAMKGVIRVKFVNdlgvdEAGIDQDGVFKEFLEEIIKRVFDPALNLFKTTSGDER-LYPSPTSYIHE-NYLQLFEFVGKMLGKAVY 787
           7899********************************************99987665.59*******76.****************** PP
   S: 84   dgrlldlplsksfyklllgk.....klsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeeeLkpgGenipV 165
           +g ++d+p++++f+++llg+       s+++l+++d+e+yk+l++ik++ + di +lgl+l++  +e+++g+  ++eL+pgG++ipV
   Q: 788  EGIVVDVPFASFFLSQLLGHhhsvfYSSVDELPSLDSEFYKNLTSIKRY-DGDIADLGLTLSY--DEDVMGQLVCHELIPGGKTIPV 871
           ********************777777999********************.6788887777766..6999****************** PP
   S: 166  tne.NkeeYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGe.eeidvedlkketkykggytedspaiqwFw 250
           tne N+ +Y++l++++r++++ik+q++a+ +Gf+++i++e++++F++ el+ li+G+ +eid+edlkk+t y gg++ ++++i+w+w
   Q: 872  TNEsNRISYIHLMAHFRMHTQIKNQTAALISGFRSIIKPEWIRMFSAPELQRLISGDnAEIDLEDLKKHTVYYGGFHGSHRVIIWLW 958
           *865*****************************************************9***************************** PP
   S: 251  evl.eefsseerkafLqFvTgssrlPlgGfaelk........................prlfvirkdasddrlPssnTCfnyLkLPe 312
           ++l ++f+ +er++fL+FvT++sr Pl Gfa+lk                        + +f+irk +   rlP+s+TCfn+LkLP+
   Q: 959  DILaSDFTPDERAMFLKFVTSCSRPPLLGFAYLKppfsircvevsddqdtgdtlgsvlRGFFTIRKREPGGRLPTSSTCFNLLKLPN 1045
           ***99*************************************************************8888***************** PP
   S: 313  YsskeilkekLlyAieetkgFels 336
           Ys+k++l+ekL+yAi++++gFels
   Q: 1046 YSKKSVLREKLRYAISMNTGFELS 1069
           *********************985 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MFTLSQTSRA WFIDRARQAR EERLVQKERE RAAVVIQAHV RSFLCRSRLQ RDIRREIDDF 60
FKADDPGSTK RSALCIFKVA RKLLFVFRIK EDNERFEKLC RSILSSMDAE NEPKVWYVSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCCCGCAGA GAGCAACGTC TTAAACGGTC CGTTGTGCGC CCAGGGGGTA GTTTTCTTTC 60
CAACCTCTCC GGCCGGAATG GGTGCCAGCT TCTCTTGGCT GGGTAAGGCG TTTATCCCGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR000569--HECT_dom
IPR000048--IQ_motif_EF-hand-BS

PROSITE

PS50237--HECT
PS50096--IQ

Pfam

PF00632--HECT
PF00612--IQ

SMART

SM00119--HECTc
SM00015--IQ

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000128	Aegilops tauschii	36.18	4.00e-105	376.00
IUUC-Aml-002107	Ailuropoda melanoleuca	96.45	0.00e+00	2088.00
IUUC-Atr-003017	Amborella trichopoda	38.41	1.00e-108	388.00
IUUC-Apl-003328	Anas platyrhynchos	88.50	0.00e+00	1854.00
IUUC-Aly-005794	Arabidopsis lyrata	38.86	4.00e-108	386.00
IUUC-Ath-007269	Arabidopsis thaliana	39.22	1.00e-110	394.00
IUUC-Bta-013547	Bos taurus	95.51	0.00e+00	2095.00
IUUC-Bdi-014502	Brachypodium distachyon	39.08	1.00e-108	388.00
IUUC-Bol-015093	Brassica oleracea	39.57	5.00e-111	395.00
IUUC-Bra-016722	Brassica rapa	39.93	8.00e-113	401.00
IUUC-Cel-018447	Caenorhabditis elegans	38.00	0.00e+00	681.00
IUUC-Cja-019855	Callithrix jacchus	98.41	0.00e+00	2131.00
IUUC-Cfa-020066	Canis familiaris	96.22	0.00e+00	2066.00
IUUC-Cpo-021504	Cavia porcellus	95.14	0.00e+00	2078.00
IUUC-Csa-023579	Chlorocebus sabaeus	99.72	0.00e+00	2155.00
IUUC-Cho-024430	Choloepus hoffmanni	85.49	0.00e+00	1543.00
IUUC-Cin-025750	Ciona intestinalis	47.58	0.00e+00	975.00
IUUC-Csv-026016	Ciona savignyi	48.18	0.00e+00	1024.00
IUUC-Dre-028271	Danio rerio	81.23	0.00e+00	1757.00
IUUC-Dno-029054	Dasypus novemcinctus	95.88	0.00e+00	2080.00
IUUC-Dor-030938	Dipodomys ordii	87.75	0.00e+00	1861.00
IUUC-Dme-031602	Drosophila melanogaster	47.88	0.00e+00	964.00
IUUC-Ete-033041	Echinops telfairi	76.41	0.00e+00	1370.00
IUUC-Eca-034411	Equus caballus	96.54	0.00e+00	2068.00
IUUC-Eeu-035201	Erinaceus europaeus	84.95	0.00e+00	804.00
IUUC-Fca-036594	Felis catus	95.23	0.00e+00	2043.00
IUUC-Fal-037317	Ficedula albicollis	84.77	0.00e+00	1863.00
IUUC-Gmo-039412	Gadus morhua	77.49	0.00e+00	1721.00
IUUC-Gga-040149	Gallus gallus	88.24	0.00e+00	1882.00
IUUC-Gac-042088	Gasterosteus aculeatus	80.04	0.00e+00	1809.00
IUUC-Gma-042728	Glycine max	40.60	2.00e-110	393.00
IUUC-Ggo-045279	Gorilla gorilla	98.69	0.00e+00	2138.00
IUUC-Hsa-045660	Homo sapiens	98.41	0.00e+00	2132.00
IUUC-Hvu-047102	Hordeum vulgare	36.18	9.00e-106	378.00
IUUC-Itr-048021	Ictidomys tridecemlineatus	94.31	0.00e+00	1058.00
IUUC-Lch-050664	Latimeria chalumnae	82.28	0.00e+00	1818.00
IUUC-Lpe-050755	Leersia perrieri	36.97	3.00e-97	350.00
IUUC-Loc-052791	Lepisosteus oculatus	82.60	0.00e+00	1779.00
IUUC-Laf-053902	Loxodonta africana	96.07	0.00e+00	2086.00
IUUC-Mcc-054730	Macaca mulatta	99.63	0.00e+00	2155.00
IUUC-Meu-056527	Macropus eugenii	79.68	0.00e+00	1670.00
IUUC-Mtr-057671	Medicago truncatula	39.72	1.00e-110	394.00
IUUC-Mga-059260	Meleagris gallopavo	87.98	0.00e+00	1886.00
IUUC-Mmr-060804	Microcebus murinus	94.67	0.00e+00	2007.00
IUUC-Mdo-062575	Monodelphis domestica	83.68	0.00e+00	1785.00
IUUC-Mmu-063636	Mus musculus	91.69	0.00e+00	1947.00
IUUC-Mac-064989	Musa acuminata	39.29	3.00e-106	380.00
IUUC-Mpu-066677	Mustela putorius furo	96.22	0.00e+00	1956.00
IUUC-Mlu-067952	Myotis lucifugus	95.14	0.00e+00	1988.00
IUUC-Nle-069153	Nomascus leucogenys	98.50	0.00e+00	2133.00
IUUC-Opr-070554	Ochotona princeps	94.59	0.00e+00	1874.00
IUUC-Ont-071372	Oreochromis niloticus	81.03	0.00e+00	1788.00
IUUC-Oan-073327	Ornithorhynchus anatinus	71.21	0.00e+00	734.00
IUUC-Ocu-074183	Oryctolagus cuniculus	95.14	0.00e+00	2044.00
IUUC-Oba-075213	Oryza barthii	38.58	2.00e-105	377.00
IUUC-Obr-076320	Oryza brachyantha	35.33	1.00e-108	388.00
IUUC-Ogl-077093	Oryza glaberrima	39.02	6.00e-108	385.00
IUUC-Ogu-078947	Oryza glumaepatula	36.75	8.00e-109	388.00
IUUC-Oin-080058	Oryza indica	39.02	7.00e-108	385.00
IUUC-Olo-080742	Oryza longistaminata	35.13	3.00e-107	383.00
IUUC-Ome-081741	Oryza meridionalis	34.67	6.00e-101	362.00
IUUC-Oni-082385	Oryza nivara	36.75	8.00e-109	388.00
IUUC-Opu-083529	Oryza punctata	35.17	6.00e-108	385.00
IUUC-Oru-085128	Oryza rufipogon	36.62	2.00e-94	340.00
IUUC-Osa-085557	Oryza sativa	39.29	2.00e-107	383.00
IUUC-Ola-087337	Oryzias latipes	80.37	0.00e+00	1726.00
IUUC-Oga-088342	Otolemur garnettii	95.88	0.00e+00	2000.00
IUUC-Oar-090234	Ovis aries	95.37	0.00e+00	2068.00
IUUC-Ptr-091661	Pan troglodytes	98.78	0.00e+00	2139.00
IUUC-Psi-093251	Pelodiscus sinensis	87.70	0.00e+00	1750.00
IUUC-Pma-094195	Petromyzon marinus	69.49	0.00e+00	1438.00
IUUC-Ppa-095544	Physcomitrella patens	37.81	7.00e-109	389.00
IUUC-Pfo-097472	Poecilia formosa	80.65	0.00e+00	1791.00
IUUC-Pab-098570	Pongo abelii	98.41	0.00e+00	2130.00
IUUC-Pca-100110	Procavia capensis	83.44	0.00e+00	1739.00
IUUC-Ppe-101281	Prunus persica	38.94	3.00e-106	380.00
IUUC-Pva-102887	Pteropus vampyrus	91.03	0.00e+00	1941.00
IUUC-Rno-106028	Rattus norvegicus	88.90	0.00e+00	1848.00
IUUC-Sha-107331	Sarcophilus harrisii	85.00	0.00e+00	1810.00
IUUC-Smo-109488	Selaginella moellendorffii	36.90	1.00e-104	374.00
IUUC-Sit-109811	Setaria italica	35.70	3.00e-110	393.00
IUUC-Sly-111362	Solanum lycopersicum	35.29	8.00e-100	358.00
IUUC-Sar-113287	Sorex araneus	85.95	0.00e+00	738.00
IUUC-Sbi-114433	Sorghum bicolor	35.61	8.00e-111	395.00
IUUC-Ssc-116103	Sus scrofa	96.45	0.00e+00	2060.00
IUUC-Tgu-117275	Taeniopygia guttata	87.86	0.00e+00	1871.00
IUUC-Tru-118681	Takifugu rubripes	79.53	0.00e+00	1797.00
IUUC-Tsy-118985	Tarsius syrichta	92.24	0.00e+00	1049.00
IUUC-Tni-120850	Tetraodon nigroviridis	90.75	0.00e+00	769.00
IUUC-Tca-121770	Theobroma cacao	39.12	2.00e-110	394.00
IUUC-Tae-125466	Triticum aestivum	36.60	6.00e-107	382.00
IUUC-Tur-126086	Triticum urartu	36.18	2.00e-104	374.00
IUUC-Tbe-127461	Tupaia belangeri	91.49	0.00e+00	1899.00
IUUC-Ttr-129269	Tursiops truncatus	95.79	0.00e+00	2041.00
IUUC-Vpa-130523	Vicugna pacos	76.68	6.00e-128	451.00
IUUC-Vvi-131524	Vitis vinifera	38.97	6.00e-108	385.00
IUUC-Xtr-132146	Xenopus tropicalis	83.60	0.00e+00	1835.00
IUUC-Xma-133526	Xiphophorus maculatus	80.37	0.00e+00	1783.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence