iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-092882

Ensembl Protein ID

ENSPANP00000007228.1

UniProt Accession

A0A096N4B5; A0A096N4B5_PAPAN

Genbank Protein ID

ENSPANP00000007228

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01023972

Gene Name

USP28

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000019172.1	ENSPANT00000018343.1	ENSPANP00000007228.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	9.30e-32	110.6	22	361

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 165  reepfldlslpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkv 253
            +e+f +++l+v+g +     +l++cLe  + e  +e    +  +   ++++  ++ +++klP+vL+++L+Rf+f+++ +++eki++k+
   Q: 22   NNETFGQYPLQVNGYR-----NLDECLEGAMVEGDVE----LLPSD--HSVKYGQERWFTKLPPVLTFELSRFEFNQSLGQPEKIHNKL 99
           4688888888998888.....8888886555544444....55444..556778899******************************** PP
   S: 254  efpleLdlspfcts........................................................................... 267
           efp+ + +++++ +                                                                           
   Q: 100  EFPQIIYMDRYMYRskelirnkrecirklkeeikilqqkleryvkygsgparfplpdmlkyviefastkpasescppesdthmtlplss 188
           **********9999778888888777777777777777777777777777777777777777777777777777776666666666666 PP
   S: 268  ..........peekqke........................................................................ 274
                     +     e                                                                        
   Q: 189  vhcpvsdqtsK-----Eststesssldvessfsspedslhkskpltssrssmempaqpaprtvtdeeinfvktclqrwrseieqdiqdl 272
           66666655550.....0455556666666666666777777777777777888888888888888888888888888888888889999 PP
   S: 275  .....................kkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetg.....staYvlfYk 336
                                ++ Y+L+av+vH+G+++ GHY+ay++n+ ++ Wl+++D +Vte+++eev++++       +aY+l+Y 
   Q: 273  knciasttqtieqmycdpllrQVPYRLHAVLVHEGQANAGHYWAYIYNQPQQsWLKYNDISVTESSWEEVERDSYgglrnVSAYCLMYI 361
           999999999999999****99***************************87778*******************8879************6 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MVQLFYGTFL TEGVREGKPF CNNETFGQYP LQVNGYRNLD ECLEGAMVEG DVELLPSDHS 60
VKYGQERWFT KLPPVLTFEL SRFEFNQSLG QPEKIHNKLE FPQIIYMDRY MYRSKELIRN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTCCCAGG AACAAATCTG AAAATCCAAT GGTGCAGCTG TTCTATGGTA CTTTCCTGAC 60
TGAAGGGGTT CGTGAAGGTA AATTCTCTGC TCTGAATTTT AATTCTAGAC CTGTGATCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR011990--TPR-like_helical_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0016604--C:nuclear body
GO:0043234--C:protein complex
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0008283--P:cell proliferation
GO:0034644--P:cellular response to UV
GO:0000077--P:DNA damage checkpoint
GO:0042771--P:intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:0016579--P:protein deubiquitination
GO:0007265--P:Ras protein signal transduction
GO:0031647--P:regulation of protein stability
GO:0010212--P:response to ionizing radiation
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Apl-004010	Anas platyrhynchos	64.58	0.00e+00	1037.00
IUUC-Aca-004741	Anolis carolinensis	61.96	0.00e+00	1024.00
IUUC-Acl-008164	Aspergillus clavatus	23.42	4.00e-14	74.30
IUUC-Afl-008717	Aspergillus flavus	35.11	3.00e-10	61.20
IUUC-Ame-011910	Astyanax mexicanus	43.32	2.00e-149	524.00
IUUC-Bgr-011993	Blumeria graminis	40.54	3.00e-12	67.80
IUUC-Cfa-020378	Canis familiaris	93.82	0.00e+00	1566.00
IUUC-Csa-023446	Chlorocebus sabaeus	99.65	0.00e+00	1656.00
IUUC-Cho-024717	Choloepus hoffmanni	81.52	0.00e+00	650.00
IUUC-Dno-029559	Dasypus novemcinctus	73.35	0.00e+00	818.00
IUUC-Ete-032828	Echinops telfairi	85.57	0.00e+00	742.00
IUUC-Fca-035753	Felis catus	84.01	0.00e+00	1384.00
IUUC-Fal-037062	Ficedula albicollis	68.45	0.00e+00	1112.00
IUUC-Fox-037752	Fusarium oxysporum	25.94	8.00e-15	76.30
IUUC-Fso-038114	Fusarium solani	34.91	2.00e-11	65.50
IUUC-Itr-048276	Ictidomys tridecemlineatus	67.40	1.00e-174	606.00
IUUC-Loc-052636	Lepisosteus oculatus	62.84	0.00e+00	1027.00
IUUC-Laf-053808	Loxodonta africana	90.49	0.00e+00	782.00
IUUC-Mcc-055473	Macaca mulatta	99.77	0.00e+00	1657.00
IUUC-Mga-060011	Meleagris gallopavo	62.17	0.00e+00	974.00
IUUC-Mdo-061955	Monodelphis domestica	85.14	0.00e+00	1363.00
IUUC-Mmu-063870	Mus musculus	85.19	0.00e+00	791.00
IUUC-Mpu-066454	Mustela putorius furo	93.12	0.00e+00	1474.00
IUUC-Nfi-068458	Neosartorya fischeri	33.96	4.00e-10	60.80
IUUC-Opr-070888	Ochotona princeps	98.19	3.00e-162	565.00
IUUC-Oar-089848	Ovis aries	92.88	0.00e+00	1559.00
IUUC-Ptr-091630	Pan troglodytes	97.93	0.00e+00	879.00
IUUC-Psi-093422	Pelodiscus sinensis	72.55	0.00e+00	1205.00
IUUC-Pma-094250	Petromyzon marinus	51.88	3.00e-80	291.00
IUUC-Pca-100901	Procavia capensis	74.85	0.00e+00	648.00
IUUC-Rno-105735	Rattus norvegicus	90.08	0.00e+00	1513.00
IUUC-Sce-106441	Saccharomyces cerevisiae	31.58	9.00e-08	53.10
IUUC-Ssl-108532	Sclerotinia sclerotiorum	34.57	7.00e-09	56.60
IUUC-Ssc-115463	Sus scrofa	90.98	0.00e+00	1107.00
IUUC-Tsy-118971	Tarsius syrichta	96.87	0.00e+00	639.00
IUUC-Tvi-122548	Trichoderma virens	36.84	4.00e-09	57.80

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence