iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Rno-105101

Ensembl Protein ID

ENSRNOP00000059742.3

UniProt Accession

D3ZSP7; D3ZSP7_RAT

Genbank Protein ID

ENSRNOP00000059742

Protein Name

Tetratricopeptide repeat domain 3

Genbank Nucleotide ID

AABR07033674

Gene Name

Ttc3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSRNOG00000001682.7	ENSRNOT00000065600.3	ENSRNOP00000059742.3

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	4.00e-08	34.0	1952	1991

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledf..kdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           C iC+e f  k+  +vl CgH fh+ C+++w       +++ +CP+C
   Q: 1952 CQICHEIFksKN-MRVLKCGHKFHKGCFKQW------LKGQSTCPTC 1991
           9*****998555.******************......********** PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MPGHRGAPHL PPWVCGLCSM DDFAEGGLSL ADDILLEDYP YEDDCICTPD FTTDDYVRVT 60
QLYYEGVGMQ YKDYAQSEKN LEYDICNIWC SKPLSILQDY CDAIKLYIFW PLLFQHQHSS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGCCTGGGC ATCGGGGCGC TCCACACCTC CCTCCGTGGG TGTGTGGTGA GTGTGGGTGT 60
GCGCGTCGCC GCGGGTCTCG CCGAGCGCCC GCGCGCCGAG GGGGTGTGGC CGCCCTTGCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat

Interpro

IPR011029--DEATH-like_dom
IPR023114--Elongated_TPR_rpt_dom
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50005--TPR
PS50293--TPR_REGION
PS50089--ZF_RING_2

Pfam

PF13639--zf-RING_2

SMART

SM00184--RING
SM00028--TPR

Gene Ontology

GO:0005829--C:cytosol
GO:0005730--C:nucleolus
GO:0005634--C:nucleus
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0070936--P:protein K48-linked ubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002231	Ailuropoda melanoleuca	87.04	9.00e-27	110.00
IUUC-Apl-003622	Anas platyrhynchos	48.04	0.00e+00	1009.00
IUUC-Aca-004579	Anolis carolinensis	36.16	1.00e-58	220.00
IUUC-Ame-011167	Astyanax mexicanus	39.25	1.00e-175	611.00
IUUC-Bta-012916	Bos taurus	71.36	0.00e+00	2581.00
IUUC-Cja-019100	Callithrix jacchus	75.37	0.00e+00	2645.00
IUUC-Cfa-020974	Canis familiaris	74.69	0.00e+00	2748.00
IUUC-Cpo-022435	Cavia porcellus	63.21	0.00e+00	1758.00
IUUC-Csa-023245	Chlorocebus sabaeus	74.85	0.00e+00	2752.00
IUUC-Cho-024822	Choloepus hoffmanni	62.78	0.00e+00	1229.00
IUUC-Cin-025626	Ciona intestinalis	32.68	4.00e-16	79.00
IUUC-Cme-027114	Cyanidioschyzon merolae	38.33	7.00e-07	48.10
IUUC-Dre-027805	Danio rerio	36.59	4.00e-106	380.00
IUUC-Dno-029413	Dasypus novemcinctus	60.53	0.00e+00	2135.00
IUUC-Dor-030670	Dipodomys ordii	79.28	0.00e+00	1471.00
IUUC-Ete-032367	Echinops telfairi	40.80	9.00e-78	286.00
IUUC-Eca-033891	Equus caballus	74.50	0.00e+00	2728.00
IUUC-Fca-035889	Felis catus	74.01	0.00e+00	2707.00
IUUC-Fal-037399	Ficedula albicollis	43.07	0.00e+00	884.00
IUUC-Gga-040490	Gallus gallus	45.71	0.00e+00	940.00
IUUC-Gac-042289	Gasterosteus aculeatus	28.17	5.00e-11	60.10
IUUC-Ggo-045441	Gorilla gorilla	71.66	0.00e+00	2569.00
IUUC-Hsa-045811	Homo sapiens	75.27	0.00e+00	2762.00
IUUC-Itr-048367	Ictidomys tridecemlineatus	71.47	0.00e+00	763.00
IUUC-Lch-049809	Latimeria chalumnae	42.24	3.00e-129	456.00
IUUC-Loc-052533	Lepisosteus oculatus	36.80	0.00e+00	690.00
IUUC-Laf-053785	Loxodonta africana	65.91	0.00e+00	1509.00
IUUC-Mcc-054801	Macaca mulatta	75.73	0.00e+00	2762.00
IUUC-Mga-059963	Meleagris gallopavo	42.24	0.00e+00	1014.00
IUUC-Mmr-060707	Microcebus murinus	75.34	0.00e+00	2688.00
IUUC-Mdo-062718	Monodelphis domestica	47.28	0.00e+00	1153.00
IUUC-Mmu-064257	Mus musculus	92.88	0.00e+00	3383.00
IUUC-Mpu-066020	Mustela putorius furo	73.14	0.00e+00	2716.00
IUUC-Mlu-067023	Myotis lucifugus	70.62	0.00e+00	2565.00
IUUC-Nle-069965	Nomascus leucogenys	75.39	0.00e+00	2736.00
IUUC-Opr-070629	Ochotona princeps	61.86	0.00e+00	922.00
IUUC-Ont-072604	Oreochromis niloticus	35.55	1.00e-152	535.00
IUUC-Oan-072830	Ornithorhynchus anatinus	46.01	0.00e+00	1400.00
IUUC-Ocu-073774	Oryctolagus cuniculus	74.20	0.00e+00	2727.00
IUUC-Ola-086847	Oryzias latipes	35.86	4.00e-148	519.00
IUUC-Oga-088372	Otolemur garnettii	73.38	0.00e+00	1984.00
IUUC-Oar-090039	Ovis aries	69.97	0.00e+00	2561.00
IUUC-Ptr-091171	Pan troglodytes	75.22	0.00e+00	2761.00
IUUC-Pan-091926	Papio anubis	72.86	0.00e+00	2754.00
IUUC-Psi-093680	Pelodiscus sinensis	48.50	0.00e+00	1033.00
IUUC-Pfo-096061	Poecilia formosa	27.04	7.00e-14	69.70
IUUC-Pab-098120	Pongo abelii	75.92	0.00e+00	2793.00
IUUC-Pva-102424	Pteropus vampyrus	65.88	0.00e+00	1348.00
IUUC-Sha-106607	Sarcophilus harrisii	61.33	0.00e+00	885.00
IUUC-Ssl-108627	Sclerotinia sclerotiorum	25.71	2.00e-06	47.40
IUUC-Sar-113589	Sorex araneus	68.37	0.00e+00	1981.00
IUUC-Ssc-115530	Sus scrofa	78.91	0.00e+00	2278.00
IUUC-Tgu-116671	Taeniopygia guttata	43.07	0.00e+00	761.00
IUUC-Tru-118283	Takifugu rubripes	34.59	1.00e-137	484.00
IUUC-Tsy-118872	Tarsius syrichta	67.63	0.00e+00	1794.00
IUUC-Tbe-127996	Tupaia belangeri	65.15	0.00e+00	1464.00
IUUC-Ttr-128379	Tursiops truncatus	72.98	0.00e+00	2563.00
IUUC-Vpa-130372	Vicugna pacos	71.18	0.00e+00	2157.00
IUUC-Xtr-132649	Xenopus tropicalis	33.93	0.00e+00	936.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence