iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Cfa-021126

Ensembl Protein ID

ENSCAFP00000013033.3

UniProt Accession

F1Q436; E2R2Y5; F1Q436_CANLF

Genbank Protein ID

ENSCAFP00000013033

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAEX03011491

Gene Name

PACSIN3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSCAFG00000008866.4	ENSCAFT00000014088.4	ENSCAFP00000013033.3
ENSCAFG00000008866.4	ENSCAFT00000014094.3	ENSCAFP00000013039.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	1.10e-13	51.2	367	421

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvek 61
           +v++lydy +q+ deL++++G+ +l +  ee ++gW++g+   +g+ Gl P+n+ve 
   Q: 367  RVRALYDYAGQEADELSFRAGEELLKM-SEEDEQGWCQGQ-LQSGRIGLYPANYVEC 421
           689********************9999.999********7.99************86 PP

Organism

Canis familiaris

Protein Sequence
(Fasta)

MAPEEDAGGE ALEGSFWEAG NYRRTVQRVE DGHRLCGDLV SCFQERARIE KAYAQQLADW 60
ARKWRGTVEK GPQYGTLEKA WHAFFTAAER LSALHLEVRE KLQGQDSERV RSWQRGAFHR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCTCCAG AGGAAGACGC TGGAGGGGAG GCCCTAGAGG GCAGTTTCTG GGAGGTGAGC 60
AGCTGGGTCC TAGGTTTGGG GGGTGGCGCT GAAATGCCCA CCCCCCTCTG GGCCCAGCCA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR027267--AH/BAR-dom
IPR031160--F_BAR
IPR001060--FCH_dom
IPR028523--PACSIN3
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF14604--SH3_9

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0005886--C:plasma membrane
GO:0019855--F:calcium channel inhibitor activity
GO:0008289--F:lipid binding
GO:0051926--P:negative regulation of calcium ion transport
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0051044--P:positive regulation of membrane protein ectodomain proteolysis
GO:0030100--P:regulation of endocytosis

KEGG

cfa:475984

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001906	Ailuropoda melanoleuca	97.90	0.00e+00	666.00
IUUC-Apl-003211	Anas platyrhynchos	64.63	3.00e-179	620.00
IUUC-Aca-004256	Anolis carolinensis	65.05	4.00e-178	617.00
IUUC-Ame-011049	Astyanax mexicanus	60.36	1.00e-153	536.00
IUUC-Bta-013322	Bos taurus	92.12	0.00e+00	767.00
IUUC-Cja-018907	Callithrix jacchus	95.05	0.00e+00	797.00
IUUC-Cpo-021491	Cavia porcellus	91.98	0.00e+00	779.00
IUUC-Csa-023107	Chlorocebus sabaeus	96.46	0.00e+00	804.00
IUUC-Dre-027933	Danio rerio	60.59	1.00e-146	512.00
IUUC-Dno-029002	Dasypus novemcinctus	92.92	0.00e+00	751.00
IUUC-Eca-033824	Equus caballus	94.34	0.00e+00	792.00
IUUC-Eeu-035122	Erinaceus europaeus	85.27	3.00e-171	593.00
IUUC-Fca-036420	Felis catus	96.93	0.00e+00	814.00
IUUC-Fal-037277	Ficedula albicollis	64.55	0.00e+00	627.00
IUUC-Gga-040941	Gallus gallus	65.21	0.00e+00	627.00
IUUC-Gac-041374	Gasterosteus aculeatus	62.05	2.00e-138	485.00
IUUC-Ggo-045211	Gorilla gorilla	95.99	0.00e+00	801.00
IUUC-Hsa-046053	Homo sapiens	96.46	0.00e+00	804.00
IUUC-Itr-047939	Ictidomys tridecemlineatus	93.87	0.00e+00	790.00
IUUC-Loc-052808	Lepisosteus oculatus	62.19	2.00e-157	548.00
IUUC-Laf-054211	Loxodonta africana	92.69	0.00e+00	750.00
IUUC-Mcc-055044	Macaca mulatta	96.46	0.00e+00	804.00
IUUC-Mga-059216	Meleagris gallopavo	65.14	0.00e+00	627.00
IUUC-Mmr-061172	Microcebus murinus	95.99	0.00e+00	806.00
IUUC-Mdo-062600	Monodelphis domestica	87.03	0.00e+00	753.00
IUUC-Mmu-063218	Mus musculus	91.98	0.00e+00	778.00
IUUC-Mpu-066819	Mustela putorius furo	98.20	0.00e+00	670.00
IUUC-Mlu-067597	Myotis lucifugus	91.18	0.00e+00	778.00
IUUC-Nle-069195	Nomascus leucogenys	95.99	0.00e+00	800.00
IUUC-Opr-071050	Ochotona princeps	93.18	0.00e+00	758.00
IUUC-Ont-071612	Oreochromis niloticus	56.06	2.00e-139	489.00
IUUC-Oan-073256	Ornithorhynchus anatinus	86.85	0.00e+00	729.00
IUUC-Ocu-074653	Oryctolagus cuniculus	94.58	0.00e+00	767.00
IUUC-Olo-080637	Oryza longistaminata	25.40	1.10e+00	28.10
IUUC-Oga-089040	Otolemur garnettii	93.87	0.00e+00	797.00
IUUC-Oar-089918	Ovis aries	95.37	0.00e+00	778.00
IUUC-Ptr-091307	Pan troglodytes	96.46	0.00e+00	804.00
IUUC-Pan-092512	Papio anubis	96.46	0.00e+00	804.00
IUUC-Pfo-096881	Poecilia formosa	60.90	4.00e-153	534.00
IUUC-Pab-098620	Pongo abelii	96.46	0.00e+00	804.00
IUUC-Pva-102464	Pteropus vampyrus	92.22	0.00e+00	768.00
IUUC-Rno-106091	Rattus norvegicus	91.51	0.00e+00	775.00
IUUC-Sha-107474	Sarcophilus harrisii	87.97	0.00e+00	750.00
IUUC-Ssc-116128	Sus scrofa	96.70	0.00e+00	810.00
IUUC-Tru-118005	Takifugu rubripes	60.86	5.00e-141	494.00
IUUC-Tni-119851	Tetraodon nigroviridis	65.22	4.00e-140	491.00
IUUC-Ttr-129313	Tursiops truncatus	95.75	0.00e+00	807.00
IUUC-Vpa-130760	Vicugna pacos	97.81	2.00e-102	365.00
IUUC-Xtr-132697	Xenopus tropicalis	56.71	2.00e-138	485.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence