iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pma-094383

UUCD1 version

UUC-PeM-00246

Ensembl Protein ID

ENSPMAP00000008113.1

UniProt Accession

S4RSC4; S4RSC4_PETMA

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPMAG00000007353.1	ENSPMAT00000008149.1	ENSPMAP00000008113.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	5.90e-42	139.1	301	331
E3 activity/RING/U-box	3.70e-23	80.6	440	510
UBD/Beta-Prp	5.40e-54	182.6	255	334

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           H+  vt++af ++ ++l++Gs D+t+k+W+l
   Q: 301  HQRYVTSCAFtPGaPYLITGSMDKTVKLWRL 331
           999********999****************8 PP

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawcee 71
           +vp+eflCpIs elM++Pv++++G++y+++ +e wl   ++t+P+t+ pl++  l+Pn +l++ i +w+e+
   Q: 440  DVPDEFLCPISRELMHNPVIAADGYSYEKKEVEAWLHGRRRTSPMTNLPLESAILIPNRALQAAIRRWLES 510
           69******************************************************************986 PP

UBD/Beta-Prp

   S: 47   slsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletg 126
           +l+gh+a+v +++fs+dg +l++gs D+ + +w++ tg+ + ++ +h+++v+s++f p   +l++Gs d+t+++w le+ 
   Q: 255  CLEGHTAPVLCCCFSSDGHVLASGSVDKSVILWNPITGEKLLSIMEHQRYVTSCAFTPGAPYLITGSMDKTVKLWRLENT 334
           589*******************************************************88*****************986 PP

Organism

Petromyzon marinus

Protein Sequence
(Fasta)

AVTLIQSLGE HADDVNCVAA SRHCLATCSS DKTVRAYALD SLREMPFSPI RAHTYAVHCC 60
CFNPDGSLLA TCSTEGTTAL WDARTGQRIT VLLQPGGGSG VRVCAFSPRP LGGDAGQAPA 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCGTGACGC TCATCCAGAG CCTCGGCGAG CACGCGGACG ACGTGAACTG CGTGGCCGCG 60
TCTCGCCACT GCCTCGCCAC CTGCTCCTCC GACAAGACCG TGCGTGCGTA CGCGCTCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001660--SAM
IPR013761--SAM/pointed
IPR003613--Ubox_domain
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50105--SAM_DOMAIN
PS51698--U_BOX
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07647--SAM_2
PF04564--U-box
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00454--SAM
SM00504--Ubox
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001614	Ailuropoda melanoleuca	49.02	7.00e-131	458.00
IUUC-Apl-003529	Anas platyrhynchos	48.83	2.00e-130	457.00
IUUC-Aca-004257	Anolis carolinensis	46.44	3.00e-121	427.00
IUUC-Ame-011357	Astyanax mexicanus	40.12	3.00e-84	303.00
IUUC-Bta-013032	Bos taurus	49.02	1.00e-130	458.00
IUUC-Cja-018743	Callithrix jacchus	49.12	4.00e-131	459.00
IUUC-Cfa-021197	Canis familiaris	48.24	4.00e-129	453.00
IUUC-Cpo-022279	Cavia porcellus	48.92	1.00e-131	461.00
IUUC-Csa-023954	Chlorocebus sabaeus	48.53	1.00e-130	457.00
IUUC-Cho-025083	Choloepus hoffmanni	37.23	2.00e-64	237.00
IUUC-Cin-025786	Ciona intestinalis	33.27	9.00e-78	282.00
IUUC-Dre-028087	Danio rerio	46.02	1.00e-113	401.00
IUUC-Dno-028919	Dasypus novemcinctus	48.53	4.00e-132	462.00
IUUC-Dor-031112	Dipodomys ordii	47.36	2.00e-125	441.00
IUUC-Ete-032405	Echinops telfairi	48.33	1.00e-85	308.00
IUUC-Eca-033254	Equus caballus	48.73	3.00e-132	463.00
IUUC-Eeu-034545	Erinaceus europaeus	45.88	1.00e-118	418.00
IUUC-Fca-035482	Felis catus	48.63	9.00e-130	455.00
IUUC-Fal-036976	Ficedula albicollis	41.89	9.00e-95	338.00
IUUC-Gmo-039213	Gadus morhua	44.88	3.00e-100	357.00
IUUC-Gga-040561	Gallus gallus	49.81	4.00e-131	459.00
IUUC-Gac-041471	Gasterosteus aculeatus	44.86	1.00e-104	371.00
IUUC-Ggo-045503	Gorilla gorilla	48.34	4.00e-130	456.00
IUUC-Hsa-045910	Homo sapiens	48.14	3.00e-129	453.00
IUUC-Itr-048214	Ictidomys tridecemlineatus	45.52	1.00e-92	331.00
IUUC-Loc-052307	Lepisosteus oculatus	47.83	1.00e-131	461.00
IUUC-Laf-053587	Loxodonta africana	48.34	3.00e-129	453.00
IUUC-Mcc-055679	Macaca mulatta	48.34	7.00e-130	455.00
IUUC-Meu-055962	Macropus eugenii	45.02	1.00e-61	229.00
IUUC-Mga-059652	Meleagris gallopavo	50.29	2.00e-132	464.00
IUUC-Mmr-060943	Microcebus murinus	46.78	1.00e-124	438.00
IUUC-Mdo-062592	Monodelphis domestica	49.22	1.00e-134	471.00
IUUC-Mmu-063577	Mus musculus	49.41	4.00e-130	456.00
IUUC-Mpu-066422	Mustela putorius furo	49.22	7.00e-131	458.00
IUUC-Mlu-067250	Myotis lucifugus	47.75	3.00e-128	450.00
IUUC-Nle-069517	Nomascus leucogenys	48.33	2.00e-129	454.00
IUUC-Opr-070776	Ochotona princeps	49.02	6.00e-131	459.00
IUUC-Ont-071447	Oreochromis niloticus	44.34	4.00e-98	350.00
IUUC-Oan-073706	Ornithorhynchus anatinus	48.34	7.00e-128	449.00
IUUC-Ocu-074766	Oryctolagus cuniculus	46.20	1.00e-120	425.00
IUUC-Ola-086531	Oryzias latipes	45.06	8.00e-110	389.00
IUUC-Oga-088388	Otolemur garnettii	48.92	8.00e-132	462.00
IUUC-Oar-089748	Ovis aries	49.61	2.00e-134	470.00
IUUC-Ptr-090616	Pan troglodytes	48.13	3.00e-128	450.00
IUUC-Pan-091769	Papio anubis	48.07	2.00e-85	307.00
IUUC-Psi-093334	Pelodiscus sinensis	49.71	8.00e-123	432.00
IUUC-Pfo-096832	Poecilia formosa	41.84	1.00e-101	361.00
IUUC-Pab-098139	Pongo abelii	45.65	1.00e-94	338.00
IUUC-Pca-100523	Procavia capensis	47.93	1.00e-82	298.00
IUUC-Pva-102286	Pteropus vampyrus	48.05	4.00e-124	436.00
IUUC-Rno-104831	Rattus norvegicus	49.02	1.00e-129	454.00
IUUC-Sha-107499	Sarcophilus harrisii	49.12	1.00e-130	457.00
IUUC-Sar-113389	Sorex araneus	48.14	2.00e-123	434.00
IUUC-Tgu-116769	Taeniopygia guttata	48.44	5.00e-129	452.00
IUUC-Tru-117674	Takifugu rubripes	42.86	6.00e-113	399.00
IUUC-Tsy-119595	Tarsius syrichta	40.45	4.00e-82	296.00
IUUC-Tni-119850	Tetraodon nigroviridis	44.73	2.00e-106	377.00
IUUC-Tbe-127938	Tupaia belangeri	44.27	2.00e-66	244.00
IUUC-Ttr-128193	Tursiops truncatus	48.37	5.00e-108	383.00
IUUC-Vpa-130275	Vicugna pacos	49.41	6.00e-132	462.00
IUUC-Xtr-131982	Xenopus tropicalis	45.38	1.00e-111	395.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence