iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Ola-087483

UUCD1 version

UUC-OrL-00955

Ensembl Protein ID

ENSORLP00000023091.1

UniProt Accession

H2MW72; H2MW72_ORYLA

Protein Name

Katanin p80 WD40 repeat-containing subunit B1; p80 katanin

Gene Name

katnb1; KATNB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSORLG00000018451.1	ENSORLT00000023092.1	ENSORLP00000023091.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	3.50e-40	134.5	145	181
UBD/Beta-Prp	4.20e-65	220.2	62	280

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvl 35
           gHtd v++laf +d + l+s+sdD+t+k+WDl++g+ 
   Q: 145  GHTDAVRSLAFsPDgKWLASASDDCTVKLWDLSQGKI 181
           8***********999*****************99975 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           hk+ + c++fs +++++a+gs++g+i+vwd++  k l++l gh+a +t++ f+p g++l+++s D +ik+wd++   +v  +kgh+d v
   Q: 62   HKTAVECIQFSLSEEQVAAGSQSGSIRVWDLEAAKILQTLMGHKASITSLGFHPYGQFLASSSMDTNIKLWDVRRKGYVFRFKGHTDAV 150
           788999*********************************************************************************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysl 186
           +sl+fsp+g++l+s+s+d t+++wdl++g+ +   ++ h+++vn+v++hp++ ll+sGs Dr vrlWdl+  +++ tl+g +t+++ s 
   Q: 151  RSLAFSPDGKWLASASDDCTVKLWDLSQGKIIT-EFKSHSAAVNIVQFHPNEYLLASGSSDRSVRLWDLEKFTMIGTLEG-DTSAISSG 237
           ********************************9.*********************************************9.******** PP
   S: 187  sfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrf 230
            f+++g +l sg++d+ ++++  +  +c++ ++     v+++++
   Q: 238  LFSPDGSCLFSGATDS-LRVFGWEPDRCIDVVRVWWGKVSDLAV 280
           **************95.677777766676666555555555555 PP

Organism

Oryzias latipes

Functional Description
(View)

Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation.

Protein Sequence
(Fasta)

MAAANPTKIY WRLQEFEAHA RPVSCLALGK STGRLLATGG EDCRVNLWSL NKANCIMSLT 60
GHKTAVECIQ FSLSEEQVAA GSQSGSIRVW DLEAAKILQT LMGHKASITS LGFHPYGQFL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGGAAGCCCC GCCCTCCCAG GAAGGCGGCT CCCCCGCCAG GCGGGACGCC TCTGCATACG 60
CTGAGGCCCG TCTGCGTCTG CGTCCAGCAT GGCTGCTGCA AACCCCACCA AGATCTACTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0493--Microtubule
KW-0498--Mitosis
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR026962--Katanin_bsu1
IPR028021--Katanin_C-terminal
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF13925--Katanin_con80
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005813--C:centrosome
GO:0008352--C:katanin complex
GO:0005874--C:microtubule
GO:0000922--C:spindle pole
GO:0051301--P:cell division
GO:0051013--P:microtubule severing
GO:0030901--P:midbrain development
GO:0007067--P:mitotic nuclear division

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000954	Aegilops tauschii	44.05	2.00e-79	291.00
IUUC-Aml-002187	Ailuropoda melanoleuca	52.82	4.00e-169	588.00
IUUC-Atr-002899	Amborella trichopoda	43.71	8.00e-92	331.00
IUUC-Apl-003305	Anas platyrhynchos	52.73	4.00e-175	607.00
IUUC-Aca-004635	Anolis carolinensis	56.60	5.00e-168	584.00
IUUC-Aly-005711	Arabidopsis lyrata	48.33	2.00e-92	333.00
IUUC-Ath-007606	Arabidopsis thaliana	48.33	1.00e-92	334.00
IUUC-Ame-010870	Astyanax mexicanus	48.59	7.00e-55	207.00
IUUC-Bta-012527	Bos taurus	56.56	4.00e-177	614.00
IUUC-Bdi-014652	Brachypodium distachyon	49.33	5.00e-94	338.00
IUUC-Bol-016374	Brassica oleracea	47.67	2.00e-91	330.00
IUUC-Bra-017390	Brassica rapa	44.81	8.00e-91	328.00
IUUC-Cja-019706	Callithrix jacchus	56.72	8.00e-170	590.00
IUUC-Cfa-020139	Canis familiaris	55.68	6.00e-132	464.00
IUUC-Cpo-021710	Cavia porcellus	56.08	1.00e-178	619.00
IUUC-Cre-022746	Chlamydomonas reinhardtii	41.39	2.00e-67	250.00
IUUC-Csa-023546	Chlorocebus sabaeus	63.68	5.00e-133	468.00
IUUC-Cin-025156	Ciona intestinalis	33.39	1.00e-103	370.00
IUUC-Csv-025962	Ciona savignyi	45.74	3.00e-79	288.00
IUUC-Dre-028215	Danio rerio	59.39	0.00e+00	697.00
IUUC-Dno-029314	Dasypus novemcinctus	64.41	2.00e-142	499.00
IUUC-Dor-030482	Dipodomys ordii	56.56	1.00e-178	619.00
IUUC-Dme-032188	Drosophila melanogaster	36.95	3.00e-63	236.00
IUUC-Eca-034143	Equus caballus	56.35	3.00e-172	598.00
IUUC-Fca-035924	Felis catus	63.68	1.00e-140	493.00
IUUC-Fal-037387	Ficedula albicollis	54.74	0.00e+00	633.00
IUUC-Gmo-038692	Gadus morhua	63.31	4.00e-152	531.00
IUUC-Gga-040597	Gallus gallus	56.03	0.00e+00	645.00
IUUC-Gac-042004	Gasterosteus aculeatus	67.65	0.00e+00	820.00
IUUC-Gma-044322	Glycine max	50.00	1.00e-92	334.00
IUUC-Ggo-044761	Gorilla gorilla	64.18	3.00e-139	488.00
IUUC-Hsa-045698	Homo sapiens	64.20	9.00e-143	500.00
IUUC-Hvu-047649	Hordeum vulgare	49.33	4.00e-94	339.00
IUUC-Itr-048697	Ictidomys tridecemlineatus	56.89	8.00e-176	610.00
IUUC-Lch-049674	Latimeria chalumnae	66.27	3.00e-163	568.00
IUUC-Lpe-051554	Leersia perrieri	50.00	7.00e-95	342.00
IUUC-Loc-052623	Lepisosteus oculatus	60.81	0.00e+00	700.00
IUUC-Laf-054587	Loxodonta africana	64.18	2.00e-149	522.00
IUUC-Mcc-055851	Macaca mulatta	64.18	3.00e-139	488.00
IUUC-Meu-056704	Macropus eugenii	56.26	0.00e+00	648.00
IUUC-Mtr-058053	Medicago truncatula	48.57	1.00e-96	347.00
IUUC-Mga-059608	Meleagris gallopavo	54.44	0.00e+00	638.00
IUUC-Mmr-061154	Microcebus murinus	56.34	5.00e-178	617.00
IUUC-Mdo-062365	Monodelphis domestica	54.55	9.00e-172	596.00
IUUC-Mmu-063754	Mus musculus	56.23	1.00e-178	619.00
IUUC-Mac-065100	Musa acuminata	44.90	7.00e-93	335.00
IUUC-Mpu-066245	Mustela putorius furo	64.18	2.00e-142	498.00
IUUC-Mlu-067692	Myotis lucifugus	56.23	5.00e-171	594.00
IUUC-Nle-070051	Nomascus leucogenys	58.03	7.00e-174	603.00
IUUC-Opr-070855	Ochotona princeps	56.84	1.00e-179	623.00
IUUC-Ont-071883	Oreochromis niloticus	70.54	0.00e+00	846.00
IUUC-Oan-073293	Ornithorhynchus anatinus	56.91	1.00e-175	609.00
IUUC-Ocu-074644	Oryctolagus cuniculus	56.84	2.00e-180	625.00
IUUC-Oba-075448	Oryza barthii	46.81	8.00e-95	341.00
IUUC-Obr-076385	Oryza brachyantha	49.33	2.00e-94	340.00
IUUC-Ogl-077427	Oryza glaberrima	49.67	6.00e-95	342.00
IUUC-Ogu-078062	Oryza glumaepatula	44.56	4.00e-85	309.00
IUUC-Oin-079811	Oryza indica	49.49	1.00e-92	334.00
IUUC-Olo-080245	Oryza longistaminata	49.49	2.00e-92	333.00
IUUC-Ome-081239	Oryza meridionalis	49.66	2.00e-92	333.00
IUUC-Oni-082640	Oryza nivara	46.81	8.00e-95	341.00
IUUC-Opu-083748	Oryza punctata	50.00	3.00e-95	343.00
IUUC-Oru-084609	Oryza rufipogon	46.81	8.00e-95	341.00
IUUC-Osa-085801	Oryza sativa	44.85	4.00e-87	315.00
IUUC-Oga-087964	Otolemur garnettii	55.34	1.00e-176	613.00
IUUC-Oar-089483	Ovis aries	55.17	8.00e-172	597.00
IUUC-Ptr-091387	Pan troglodytes	64.20	9.00e-143	500.00
IUUC-Pan-092623	Papio anubis	64.18	3.00e-139	488.00
IUUC-Psi-093830	Pelodiscus sinensis	55.45	3.00e-179	621.00
IUUC-Ppa-095379	Physcomitrella patens	48.68	3.00e-88	320.00
IUUC-Pfo-096755	Poecilia formosa	71.52	0.00e+00	857.00
IUUC-Pab-097564	Pongo abelii	64.18	7.00e-139	487.00
IUUC-Pop-099149	Populus trichocarpa	45.71	4.00e-94	339.00
IUUC-Pca-100357	Procavia capensis	70.95	4.00e-89	322.00
IUUC-Ppe-101237	Prunus persica	47.91	2.00e-94	340.00
IUUC-Pva-102397	Pteropus vampyrus	54.56	7.00e-158	550.00
IUUC-Rno-105349	Rattus norvegicus	56.51	2.00e-178	619.00
IUUC-Smo-109379	Selaginella moellendorffii	48.11	2.00e-88	320.00
IUUC-Sit-110360	Setaria italica	49.67	2.00e-94	340.00
IUUC-Sly-111307	Solanum lycopersicum	48.00	2.00e-89	323.00
IUUC-Stu-112462	Solanum tuberosum	46.53	4.00e-87	315.00
IUUC-Sar-112953	Sorex araneus	55.70	2.00e-71	263.00
IUUC-Sbi-114389	Sorghum bicolor	43.85	2.00e-85	310.00
IUUC-Ssc-115949	Sus scrofa	51.91	2.00e-109	389.00
IUUC-Tgu-117461	Taeniopygia guttata	54.63	0.00e+00	633.00
IUUC-Tru-117865	Takifugu rubripes	66.35	0.00e+00	820.00
IUUC-Tsy-119036	Tarsius syrichta	68.50	9.00e-47	181.00
IUUC-Tni-120903	Tetraodon nigroviridis	65.08	0.00e+00	764.00
IUUC-Tca-121185	Theobroma cacao	46.62	3.00e-91	330.00
IUUC-Tae-125668	Triticum aestivum	49.68	1.00e-94	340.00
IUUC-Tur-126181	Triticum urartu	44.07	3.00e-84	306.00
IUUC-Tbe-127518	Tupaia belangeri	45.45	5.00e-36	145.00
IUUC-Ttr-128172	Tursiops truncatus	57.17	4.00e-176	611.00
IUUC-Vvi-131489	Vitis vinifera	47.91	3.00e-94	339.00
IUUC-Xtr-132915	Xenopus tropicalis	55.95	0.00e+00	634.00
IUUC-Xma-134133	Xiphophorus maculatus	71.69	0.00e+00	857.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence