iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mga-059205

Ensembl Protein ID

ENSMGAP00000011342.2

UniProt Accession

G1NEI2; G1NEI2_MELGA

Protein Name

Uncharacterized protein

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMGAG00000010882.2	ENSMGAT00000012216.2	ENSMGAP00000011342.2
ENSMGAG00000010882.2	ENSMGAT00000018476.1	ENSMGAP00000018008.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	6.40e-15	55.2	7	79

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfrefl 73
           de +++ +s++++r+++ + v +vld  l   l +eeke    aa   g+ ++ae+LL  +       gWf efl
   Q: 7    DERFLYMISCFRPRLKRCIRVHPVLD-WLP-SLSAEEKERVRVAALQRGEVEGAEELLRAVergPRGPGWFTEFL 79
           68899*********************.555.9********999999***************99888889*99996 PP

Organism

Meleagris gallopavo

Protein Sequence
(Fasta)

MLEECRDERF LYMISCFRPR LKRCIRVHPV LDWLPSLSAE EKERVRVAAL QRGEVEGAEE 60
LLRAVERGPR GPGWFTEFLL ALKKGGCDLA ACYVNPSQLP SPREEDDHDL CVHLVQLLHG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCGGGGTTC ATTTTAAGTG TCCGGGAACG GGGCAGCCTG AGAACAGCTG ACGTCGAGCT 60
GGTGAGTTCG GCTTCTTCGG CCGCCCATGC AGCCCCCGCT CTCTGCAGAA GCGGAGCCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0547--Nucleotide-binding
KW-1185--Reference proteome

Interpro

IPR016024--ARM-type_fold
IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	59.73	0.00e+00	1142.00
IUUC-Apl-003900	Anas platyrhynchos	81.43	0.00e+00	1646.00
IUUC-Aca-005329	Anolis carolinensis	63.17	0.00e+00	1113.00
IUUC-Ame-011305	Astyanax mexicanus	48.92	0.00e+00	886.00
IUUC-Bta-012361	Bos taurus	59.79	0.00e+00	1096.00
IUUC-Bdi-014006	Brachypodium distachyon	21.53	7.20e-02	32.70
IUUC-Cel-018230	Caenorhabditis elegans	26.46	3.00e-57	216.00
IUUC-Cja-018760	Callithrix jacchus	59.71	0.00e+00	1080.00
IUUC-Cfa-020321	Canis familiaris	58.32	0.00e+00	1112.00
IUUC-Cpo-022450	Cavia porcellus	59.17	0.00e+00	1092.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	31.62	1.00e-09	58.90
IUUC-Csa-024194	Chlorocebus sabaeus	60.17	0.00e+00	1092.00
IUUC-Cho-024364	Choloepus hoffmanni	54.61	0.00e+00	750.00
IUUC-Cin-025792	Ciona intestinalis	31.73	2.00e-80	292.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	25.86	3.00e-22	100.00
IUUC-Dre-028305	Danio rerio	54.74	0.00e+00	714.00
IUUC-Dno-029831	Dasypus novemcinctus	59.65	0.00e+00	1132.00
IUUC-Dor-030410	Dipodomys ordii	66.96	0.00e+00	817.00
IUUC-Ete-032950	Echinops telfairi	61.75	2.00e-149	523.00
IUUC-Eca-034279	Equus caballus	59.88	0.00e+00	1120.00
IUUC-Eeu-034678	Erinaceus europaeus	57.77	0.00e+00	1093.00
IUUC-Fca-035618	Felis catus	66.08	0.00e+00	742.00
IUUC-Fal-037106	Ficedula albicollis	81.70	0.00e+00	1500.00
IUUC-Fso-038398	Fusarium solani	26.62	1.00e-29	125.00
IUUC-Gmo-038598	Gadus morhua	50.43	0.00e+00	690.00
IUUC-Gga-040467	Gallus gallus	93.35	0.00e+00	1893.00
IUUC-Gac-042316	Gasterosteus aculeatus	48.32	0.00e+00	854.00
IUUC-Ggo-045461	Gorilla gorilla	61.08	0.00e+00	1087.00
IUUC-Hsa-045771	Homo sapiens	60.89	0.00e+00	1081.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	59.96	0.00e+00	1111.00
IUUC-Lch-049913	Latimeria chalumnae	66.67	0.00e+00	939.00
IUUC-Loc-052768	Lepisosteus oculatus	53.50	0.00e+00	1013.00
IUUC-Laf-053933	Loxodonta africana	59.55	0.00e+00	1091.00
IUUC-Mcc-054695	Macaca mulatta	60.17	0.00e+00	1095.00
IUUC-Meu-056829	Macropus eugenii	61.10	0.00e+00	927.00
IUUC-Mvi-060497	Microbotryum violaceum	28.63	7.00e-29	123.00
IUUC-Mmr-060703	Microcebus murinus	59.19	0.00e+00	1087.00
IUUC-Mdo-063079	Monodelphis domestica	59.67	0.00e+00	1176.00
IUUC-Mmu-064066	Mus musculus	60.12	0.00e+00	1142.00
IUUC-Mpu-066261	Mustela putorius furo	58.30	0.00e+00	1134.00
IUUC-Mlu-068196	Myotis lucifugus	58.00	0.00e+00	1082.00
IUUC-Nfi-068405	Neosartorya fischeri	27.41	3.00e-26	114.00
IUUC-Nle-069479	Nomascus leucogenys	60.35	0.00e+00	1083.00
IUUC-Opr-070717	Ochotona princeps	55.16	0.00e+00	780.00
IUUC-Ont-071702	Oreochromis niloticus	49.20	0.00e+00	911.00
IUUC-Oan-073639	Ornithorhynchus anatinus	60.48	0.00e+00	1046.00
IUUC-Ocu-074521	Oryctolagus cuniculus	59.75	0.00e+00	1116.00
IUUC-Ola-086351	Oryzias latipes	46.27	0.00e+00	813.00
IUUC-Oga-088539	Otolemur garnettii	58.85	0.00e+00	1090.00
IUUC-Oar-090186	Ovis aries	59.28	0.00e+00	1086.00
IUUC-Ptr-090575	Pan troglodytes	59.86	0.00e+00	1073.00
IUUC-Pan-092371	Papio anubis	60.17	0.00e+00	1093.00
IUUC-Psi-093072	Pelodiscus sinensis	73.75	0.00e+00	1481.00
IUUC-Pma-094345	Petromyzon marinus	45.26	5.00e-102	364.00
IUUC-Pfo-096401	Poecilia formosa	54.38	0.00e+00	707.00
IUUC-Pab-097623	Pongo abelii	60.39	0.00e+00	1079.00
IUUC-Pca-100993	Procavia capensis	53.52	0.00e+00	874.00
IUUC-Pva-102227	Pteropus vampyrus	56.01	0.00e+00	1020.00
IUUC-Pgr-103529	Puccinia graminis	35.77	2.00e-14	75.10
IUUC-Rno-105198	Rattus norvegicus	59.57	0.00e+00	1125.00
IUUC-Sha-107622	Sarcophilus harrisii	61.51	0.00e+00	1180.00
IUUC-Ssl-108450	Sclerotinia sclerotiorum	31.25	2.20e-01	32.30
IUUC-Sar-113625	Sorex araneus	66.16	4.00e-119	422.00
IUUC-Ssc-116120	Sus scrofa	34.29	8.00e-88	318.00
IUUC-Tgu-117486	Taeniopygia guttata	79.34	0.00e+00	1542.00
IUUC-Tru-118445	Takifugu rubripes	46.33	0.00e+00	833.00
IUUC-Tsy-119512	Tarsius syrichta	58.11	0.00e+00	1022.00
IUUC-Tni-120711	Tetraodon nigroviridis	46.10	0.00e+00	854.00
IUUC-Tre-122194	Trichoderma reesei	24.08	1.00e-17	85.50
IUUC-Tbe-127644	Tupaia belangeri	53.21	0.00e+00	950.00
IUUC-Ttr-128989	Tursiops truncatus	55.52	0.00e+00	1032.00
IUUC-Vpa-130587	Vicugna pacos	57.22	0.00e+00	920.00
IUUC-Xtr-132127	Xenopus tropicalis	53.56	0.00e+00	1035.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence