iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mlu-068196

Ensembl Protein ID

ENSMLUP00000008664.2

UniProt Accession

G1PDV2; G1PDV2_MYOLU

Genbank Protein ID

ENSMLUP00000008664

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAPE02004849

Gene Name

IFIH1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMLUG00000009505.2	ENSMLUT00000009507.2	ENSMLUP00000008664.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/CARD	2.50e-39	133.7	9	81

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/CARD

   S: 2    deeyrlllstlqdrvrklLdvtdvldkylseflleeekelilaaaetkgnmqaaelLLktL...vqkegWfrefl 73
           d ++ +lls++++rvr+++ v++vld yl+ fl++e ke+i+  ++t gn  aaelLL+tL   v+  gW+r f+
   Q: 9    DKNFHYLLSCFRARVRRYIEVEPVLD-YLT-FLPAEAKEQIQTRVATHGNIGAAELLLSTLakgVWPPGWTRIFV 81
           789***********************.***.****************************************9886 PP

Organism

Myotis lucifugus

Protein Sequence
(Fasta)

TMANGHSADK NFHYLLSCFR ARVRRYIEVE PVLDYLTFLP AEAKEQIQTR VATHGNIGAA 60
ELLLSTLAKG VWPPGWTRIF VEALRRAGNP LAARYMDPEL RDLPSPSSEN ANDECFQLLT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACGATGGCGA ATGGGCATTC CGCGGACAAG AATTTCCATT ATCTCCTCTC GTGCTTCCGG 60
GCCCGAGTGA GAAGGTACAT CGAGGTGGAG CCCGTGCTGG ACTACCTGAC CTTCCTGCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc

Interpro

IPR031964--CARD_dom
IPR011029--DEATH-like_dom
IPR006935--Helicase/UvrB_N
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR021673--RLR_CTR

PROSITE

PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS51789--RLR_CTR

Pfam

PF16739--CARD_2
PF00271--Helicase_C
PF04851--ResIII
PF11648--RIG-I_C-RD

SMART

SM00487--DEXDc
SM00490--HELICc

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005524--F:ATP binding
GO:0003677--F:DNA binding
GO:0003725--F:double-stranded RNA binding
GO:0016817--F:hydrolase activity, acting on acid anhydrides
GO:0043021--F:ribonucleoprotein complex binding
GO:0003727--F:single-stranded RNA binding
GO:0008270--F:zinc ion binding
GO:0045087--P:innate immune response
GO:0039530--P:MDA-5 signaling pathway
GO:0032727--P:positive regulation of interferon-alpha production
GO:0032728--P:positive regulation of interferon-beta production
GO:0016925--P:protein sumoylation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001336	Ailuropoda melanoleuca	81.71	0.00e+00	1601.00
IUUC-Apl-003900	Anas platyrhynchos	59.59	0.00e+00	1165.00
IUUC-Aca-005329	Anolis carolinensis	59.06	0.00e+00	1027.00
IUUC-Ame-011305	Astyanax mexicanus	47.57	0.00e+00	879.00
IUUC-Bta-012361	Bos taurus	82.31	0.00e+00	1582.00
IUUC-Bci-013674	Botrytis cinerea	36.59	1.70e+00	28.10
IUUC-Cja-018760	Callithrix jacchus	80.50	0.00e+00	1530.00
IUUC-Cfa-020321	Canis familiaris	81.52	0.00e+00	1556.00
IUUC-Cpo-022450	Cavia porcellus	75.24	0.00e+00	1488.00
IUUC-Cre-022916	Chlamydomonas reinhardtii	32.79	4.00e-13	70.50
IUUC-Csa-024194	Chlorocebus sabaeus	83.63	0.00e+00	1540.00
IUUC-Cho-024364	Choloepus hoffmanni	72.11	0.00e+00	1017.00
IUUC-Cgl-026385	Colletotrichum gloeosporioides	23.75	2.00e-23	105.00
IUUC-Dre-028305	Danio rerio	47.91	0.00e+00	790.00
IUUC-Dno-029831	Dasypus novemcinctus	81.66	0.00e+00	1570.00
IUUC-Dor-030410	Dipodomys ordii	74.81	0.00e+00	1193.00
IUUC-Ete-032950	Echinops telfairi	75.58	0.00e+00	654.00
IUUC-Eca-034279	Equus caballus	84.96	0.00e+00	1624.00
IUUC-Eeu-034678	Erinaceus europaeus	77.34	0.00e+00	1549.00
IUUC-Fca-035618	Felis catus	85.59	0.00e+00	983.00
IUUC-Fal-037106	Ficedula albicollis	57.90	0.00e+00	1069.00
IUUC-Fso-038398	Fusarium solani	32.21	9.00e-16	80.10
IUUC-Gmo-038598	Gadus morhua	49.44	0.00e+00	684.00
IUUC-Gga-040467	Gallus gallus	59.02	0.00e+00	1159.00
IUUC-Gac-042316	Gasterosteus aculeatus	48.09	0.00e+00	833.00
IUUC-Ggo-045461	Gorilla gorilla	82.94	0.00e+00	1524.00
IUUC-Hsa-045771	Homo sapiens	82.85	0.00e+00	1522.00
IUUC-Itr-048762	Ictidomys tridecemlineatus	79.43	0.00e+00	1528.00
IUUC-Lch-049913	Latimeria chalumnae	65.94	0.00e+00	935.00
IUUC-Loc-052768	Lepisosteus oculatus	54.09	0.00e+00	995.00
IUUC-Laf-053933	Loxodonta africana	81.50	0.00e+00	1550.00
IUUC-Mcc-054695	Macaca mulatta	83.72	0.00e+00	1545.00
IUUC-Meu-056829	Macropus eugenii	72.40	0.00e+00	1112.00
IUUC-Mga-059205	Meleagris gallopavo	59.18	0.00e+00	1150.00
IUUC-Mvi-060497	Microbotryum violaceum	34.21	8.00e-17	83.60
IUUC-Mmr-060703	Microcebus murinus	82.05	0.00e+00	1520.00
IUUC-Mdo-063079	Monodelphis domestica	70.28	0.00e+00	1402.00
IUUC-Mmu-064066	Mus musculus	77.86	0.00e+00	1574.00
IUUC-Mpu-066261	Mustela putorius furo	81.58	0.00e+00	1576.00
IUUC-Nfi-068405	Neosartorya fischeri	23.64	3.00e-22	101.00
IUUC-Nle-069479	Nomascus leucogenys	80.65	0.00e+00	1493.00
IUUC-Opr-070717	Ochotona princeps	71.87	0.00e+00	1108.00
IUUC-Ont-071702	Oreochromis niloticus	47.54	0.00e+00	862.00
IUUC-Oan-073639	Ornithorhynchus anatinus	65.44	0.00e+00	1173.00
IUUC-Ocu-074521	Oryctolagus cuniculus	81.15	0.00e+00	1555.00
IUUC-Ola-086351	Oryzias latipes	45.81	0.00e+00	809.00
IUUC-Oga-088539	Otolemur garnettii	79.90	0.00e+00	1510.00
IUUC-Oar-090186	Ovis aries	81.82	0.00e+00	1542.00
IUUC-Ptr-090575	Pan troglodytes	80.55	0.00e+00	1486.00
IUUC-Pan-092371	Papio anubis	83.72	0.00e+00	1543.00
IUUC-Psi-093072	Pelodiscus sinensis	61.58	0.00e+00	1233.00
IUUC-Pma-094345	Petromyzon marinus	42.18	2.00e-93	336.00
IUUC-Pfo-096401	Poecilia formosa	45.26	0.00e+00	764.00
IUUC-Pab-097623	Pongo abelii	82.55	0.00e+00	1532.00
IUUC-Pca-100993	Procavia capensis	73.85	0.00e+00	1251.00
IUUC-Pva-102227	Pteropus vampyrus	79.80	0.00e+00	1488.00
IUUC-Rno-105198	Rattus norvegicus	76.85	0.00e+00	1550.00
IUUC-Sha-107622	Sarcophilus harrisii	71.07	0.00e+00	1387.00
IUUC-Sar-113625	Sorex araneus	85.50	4.00e-162	565.00
IUUC-Tgu-117486	Taeniopygia guttata	58.31	0.00e+00	1096.00
IUUC-Tru-118445	Takifugu rubripes	45.73	0.00e+00	822.00
IUUC-Tsy-119512	Tarsius syrichta	79.43	0.00e+00	1445.00
IUUC-Tni-120711	Tetraodon nigroviridis	45.26	0.00e+00	851.00
IUUC-Tbe-127644	Tupaia belangeri	72.27	0.00e+00	1340.00
IUUC-Ttr-128989	Tursiops truncatus	79.18	0.00e+00	1580.00
IUUC-Vpa-130587	Vicugna pacos	78.38	0.00e+00	1249.00
IUUC-Xtr-132127	Xenopus tropicalis	52.45	0.00e+00	1027.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence