iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118096

UUCD1 version

UUC-TaR-00336

Ensembl Protein ID

ENSTRUP00000017059.1

UniProt Accession

H2SXC1; H2SXC1_TAKRU

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000006949.1	ENSTRUT00000017132.1	ENSTRUP00000017059.1
ENSTRUG00000006949.1	ENSTRUT00000017133.1	ENSTRUP00000017060.1
ENSTRUG00000006949.1	ENSTRUT00000017134.1	ENSTRUP00000017061.1
ENSTRUG00000006949.1	ENSTRUT00000017135.1	ENSTRUP00000017062.1
ENSTRUG00000006949.1	ENSTRUT00000017136.1	ENSTRUP00000017063.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/ZnF/NZF	1.80e-11	44.5	196	222
ULD/UDP/UBQ/UBQ_Other	9.30e-11	42.7	59	128

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/ZnF/NZF

   S: 3    aqWaCsaCTflNePeavkCemCsrpRg 29
           ++W+C++CT++N+P +++Ce+Cs+ R+
   Q: 196  QGWSCPSCTYINKPTRPGCEICSTNRP 222
           79***********************98 PP

ULD/UDP/UBQ/UBQ_Other

   S: 3    vtvksldgs.eltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiL.eddktLadygl.kdgstihll 70
           v+v+++ +s   t+kv p++t a LK++++ + g++p+ qr+++ G++L  d ++La+yg+ +dg+t++l+
   Q: 59   VVVEDSSSScCVTVKVFPHMTTAALKQQVFLEYGFHPRVQRWVI-GQCLcADQRSLASYGVhQDGDTAFLY 128
           7899999999**********************************.**************882578888886 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

LLEGVNKAQE TCIELSHAIE AGDMQSASVL AATLARQHVT VQIQASARDY EDNEISLAVV 60
VEDSSSSCCV TVKVFPHMTT AALKQQVFLE YGFHPRVQRW VIGQCLCADQ RSLASYGVHQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGAACACAGC TCGGGACCAT AGGGGACCAC CAAGAGAACC GCGCTGCCAG TTTATTTTCT 60
ACATGTGTCT GTGGATGAAA TGTCGCTGAG TTCGGGCGGT TGGACACGCA CTTCTCCAGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR029071--Ubiquitin-rel_dom
IPR027370--Znf-RING_LisH
IPR001876--Znf_RanBP2
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
IPR017907--Znf_RING_CS

PROSITE

PS01358--ZF_RANBP2_1
PS50199--ZF_RANBP2_2
PS00518--ZF_RING_1
PS50089--ZF_RING_2

Pfam

PF00641--zf-RanBP
PF13445--zf-RING_UBOX

SMART

SM00547--ZnF_RBZ

Gene Ontology

GO:0071797--C:LUBAC complex
GO:0043130--F:ubiquitin binding
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0048701--P:embryonic cranial skeleton morphogenesis
GO:0071600--P:otic vesicle morphogenesis
GO:0043123--P:positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0097039--P:protein linear polyubiquitination

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001540	Ailuropoda melanoleuca	52.52	3.00e-138	485.00
IUUC-Apl-003627	Anas platyrhynchos	72.73	3.00e-16	76.30
IUUC-Aca-004762	Anolis carolinensis	54.14	6.00e-165	574.00
IUUC-Ame-011545	Astyanax mexicanus	65.71	0.00e+00	674.00
IUUC-Bta-013247	Bos taurus	52.55	1.00e-138	486.00
IUUC-Cja-018880	Callithrix jacchus	52.31	8.00e-139	486.00
IUUC-Cfa-020477	Canis familiaris	52.50	2.00e-135	475.00
IUUC-Cpo-021558	Cavia porcellus	51.25	2.00e-135	475.00
IUUC-Csa-024129	Chlorocebus sabaeus	51.76	1.00e-134	473.00
IUUC-Cin-025630	Ciona intestinalis	40.24	8.00e-87	314.00
IUUC-Csv-026069	Ciona savignyi	54.40	8.00e-83	299.00
IUUC-Dre-028569	Danio rerio	70.44	0.00e+00	797.00
IUUC-Dno-029015	Dasypus novemcinctus	52.31	4.00e-142	498.00
IUUC-Eca-034295	Equus caballus	47.83	2.00e-126	446.00
IUUC-Fca-036380	Felis catus	52.31	7.00e-139	487.00
IUUC-Fal-037440	Ficedula albicollis	61.02	9.00e-20	87.80
IUUC-Gmo-038561	Gadus morhua	69.63	2.00e-177	615.00
IUUC-Gga-040198	Gallus gallus	47.60	4.00e-47	181.00
IUUC-Gac-041319	Gasterosteus aculeatus	80.27	0.00e+00	785.00
IUUC-Ggo-044456	Gorilla gorilla	39.73	5.00e-85	308.00
IUUC-Hsa-045738	Homo sapiens	51.96	2.00e-135	476.00
IUUC-Lch-050269	Latimeria chalumnae	53.06	1.00e-154	540.00
IUUC-Loc-052776	Lepisosteus oculatus	67.79	0.00e+00	703.00
IUUC-Laf-054269	Loxodonta africana	52.11	1.00e-136	479.00
IUUC-Mcc-055669	Macaca mulatta	51.96	2.00e-135	475.00
IUUC-Meu-055912	Macropus eugenii	51.97	4.00e-28	118.00
IUUC-Mga-059615	Meleagris gallopavo	69.23	5.00e-22	95.10
IUUC-Mmr-061562	Microcebus murinus	54.78	1.00e-129	456.00
IUUC-Mdo-062263	Monodelphis domestica	51.92	3.00e-149	521.00
IUUC-Mmu-064325	Mus musculus	51.56	2.00e-135	475.00
IUUC-Mpu-066385	Mustela putorius furo	52.50	1.00e-138	486.00
IUUC-Nle-069812	Nomascus leucogenys	52.31	6.00e-136	477.00
IUUC-Opr-070575	Ochotona princeps	66.67	1.00e-75	276.00
IUUC-Ont-071314	Oreochromis niloticus	77.55	0.00e+00	771.00
IUUC-Ola-087012	Oryzias latipes	76.15	0.00e+00	817.00
IUUC-Oga-087986	Otolemur garnettii	51.37	1.00e-133	469.00
IUUC-Oar-089600	Ovis aries	52.16	1.00e-141	496.00
IUUC-Ptr-091224	Pan troglodytes	51.96	1.00e-135	476.00
IUUC-Pan-092739	Papio anubis	52.16	3.00e-136	478.00
IUUC-Pma-094407	Petromyzon marinus	47.08	2.00e-133	469.00
IUUC-Pfo-096767	Poecilia formosa	73.86	0.00e+00	845.00
IUUC-Pab-098627	Pongo abelii	51.76	3.00e-133	468.00
IUUC-Pca-100641	Procavia capensis	52.04	8.00e-131	460.00
IUUC-Pva-102670	Pteropus vampyrus	51.74	1.00e-136	479.00
IUUC-Rno-105504	Rattus norvegicus	50.97	3.00e-134	471.00
IUUC-Sha-107342	Sarcophilus harrisii	53.07	3.00e-156	545.00
IUUC-Sar-113425	Sorex araneus	59.57	3.00e-78	285.00
IUUC-Ssc-115904	Sus scrofa	68.21	7.00e-73	266.00
IUUC-Tni-120890	Tetraodon nigroviridis	80.91	0.00e+00	739.00
IUUC-Tbe-127578	Tupaia belangeri	56.21	2.00e-131	462.00
IUUC-Ttr-129107	Tursiops truncatus	51.16	5.00e-134	471.00
IUUC-Vpa-130353	Vicugna pacos	56.25	1.00e-59	223.00
IUUC-Xtr-132168	Xenopus tropicalis	45.74	6.00e-126	444.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence