iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Bra-016751

Ensembl Protein ID

Bra005555.1-P

UniProt Accession

M4CMW7; M4CMW7_BRARP

Protein Name

Ubiquitinyl hydrolase 1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Bra005555	Bra005555.1	Bra005555.1-P

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.20e-77	261.6	200	1165

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 2    GlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelw...kskkkavsprellkalkkeaeefsgyeqqDa 92
           Gl NlgNtC++NSvLQ L+++  lr+ l++ + +++         g+l++sl+klf+e +      +++++p +++ +l+++a++f+gy+q+D+
   Q: 200  GLVNLGNTCFFNSVLQNLLSLDRLRDRLFK-EDQSCG--------GPLVSSLKKLFTEATseaGLFNSVINPWDFFGSLCSKAPQFRGYQQHDS 284
           9*****************************.666665........69************865555567************************** PP
   S: 93   qEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke. 185
           +E+l++lld+l+ e ++                  +++ + +++++++l++ +F+g+++s+i clec+++s+ +epfldlslpvp+k++t  + 
   Q: 285  HELLRCLLDGLSMEESS-----------------LRKKHDADESEKPTLVDYVFGGEVSSTISCLECGHSSKVYEPFLDLSLPVPSKKQTLSQe 361
           ************99922.................223456789999***************************************999887669 PP
   S: 186  .............................................................................................. 185
                                                                                                         
   Q: 362  ersklspptkvlenvadskdssepvstmtfdnnqvpeiivtqkdmeevgsflcesfgievshnetdlvsqggvsdnedrsakrkdkepimqcsk 455
           9********************************************************************************************* PP
   S: 186  .............................................................................................. 185
                                                                                                         
   Q: 456  dtalngideaqvwgypdleqssssanpladeevpllvvdsqvmnmpykddkavaegkgakqacsivrqtfesstetlmhdndrsakpdkeamqc 549
           ********************************************************************************************** PP
   S: 186  .............................................................................................. 185
                                                                                                         
   Q: 550  skdtasseisaeideaqvwgypdighsfsfakpcadeevpllvadsqggvsvndegsakqkdkeaimqcskdtassgideaqvwgypanplane 643
           ********************************************************************************************** PP
   S: 186  .............................................................................................. 185
                                                                                                         
   Q: 644  elpllvvdsqvmnmpykddisyddktaaegkgekqacsivrqtfesstetlmhdndgsakpdkedaqamqcsketasseiseeidighssssak 737
           ********************************************************************************************** PP
   S: 186  .............................................................................................. 185
                                                                                                         
   Q: 738  pcadeevpllvadsqvlympykddktvaedkgetsssyvsghhdqtvdyvdfswffkepdvscddktvrecedevssslvsshhgktvdyavln 831
           ********************************************************************************************** PP
   S: 186  .............................................................................................. 185
                                                                                                         
   Q: 832  epdvscndktvkeregevtsslvsshhgktvdyavlnepdvscgdktvkecegeapssfvsshhgqkidnadyywffeepevskgpafgpptka 925
           ********************************************************************************************** PP
   S: 186  ...........................slqdcLesftkeeelegenkyycekck...........................kkqe......... 216
                                      s++ cL++ftk+e l ++n+++ce+c                               +         
   Q: 926  evseagfmgvscnsdaevvlddsdspvSVDTCLAMFTKPEILSEDNAWHCENCSknlklqrlrekrerfgygwvydngfdeC--Rddifnqsfi 1017
           ******************************************************5555555555555555555555555550..0555555555 PP
   S: 217  ........................aekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdlspfctspeekqke.kkkYeLiavvv 285
                                   a k+++++k P+vL++hLkRfs +  q++ +k+  +v f + +dl  ++  ++++++e +  Y L + v 
   Q: 1018 dfnnwdtiyddeavdseevvvrraAIKRVQVNKAPPVLTIHLKRFSQDA-QGRLSKLRGHVAFSEFIDLGLYMDMDSRQDEEdQPVYMLAGLVE 1110
           555555555555555555666666*********************7665.69999*********99****9988766655544889******** PP
   S: 286  HsGslssGHYvayvknekgk......WllfdDskVtevkeeevleetgstaYvlfYkr 337
           HsG+++ GHYvay++ ++++      W++ +Ds V++v+ eevl    s+aY+lfY+r
   Q: 1111 HSGTMRRGHYVAYIRGDDKErrdssvWYRASDSFVRQVSFEEVLP---SEAYILFYQR 1165
           ***************97777788999*******************...********98 PP

Organism

Brassica rapa

Protein Sequence
(Fasta)

MGKQLKKGRA PPGGNQFSKK VAKQSAETVM EQRCCVHFDK CVDLNKLLKK MKACKEIKCG 60
ECKEGVDMKR RSEGKVSSFS CDAAKRAVWL CLECGRYCCG GVGLPTEPQS HVMHHIKMTC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGGAAGC AGTTAAAGAA AGGTCGAGCT CCTCCAGGTG GGAATCAGTT CTCCAAGAAG 60
GTAGCTAAGC AAAGCGCGGA GACAGTGATG GAACAAAGAT GTTGTGTGCA TTTTGATAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom
IPR013083--Znf_RING/FYVE/PHD
IPR001607--Znf_UBP

PROSITE

PS00972--USP_1
PS00973--USP_2
PS50235--USP_3
PS50271--ZF_UBP

Pfam

PF00443--UCH
PF02148--zf-UBP

SMART

SM00290--ZnF_UBP

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0008270--F:zinc ion binding
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000997	Aegilops tauschii	39.51	4.00e-50	192.00
IUUC-Aml-001931	Ailuropoda melanoleuca	28.47	1.00e-32	134.00
IUUC-Apl-004145	Anas platyrhynchos	29.41	8.00e-35	142.00
IUUC-Aca-004284	Anolis carolinensis	29.89	2.00e-29	124.00
IUUC-Aly-006422	Arabidopsis lyrata	52.29	9.00e-128	451.00
IUUC-Ath-006732	Arabidopsis thaliana	43.59	1.00e-142	500.00
IUUC-Bta-013362	Bos taurus	29.29	9.00e-34	138.00
IUUC-Bdi-014465	Brachypodium distachyon	35.98	1.00e-49	191.00
IUUC-Bol-015941	Brassica oleracea	73.58	0.00e+00	1038.00
IUUC-Cja-019177	Callithrix jacchus	28.74	2.00e-32	134.00
IUUC-Cfa-020051	Canis familiaris	29.37	1.00e-32	134.00
IUUC-Cpo-021886	Cavia porcellus	29.43	6.00e-35	142.00
IUUC-Csa-024103	Chlorocebus sabaeus	28.98	2.00e-33	137.00
IUUC-Dre-028106	Danio rerio	28.65	8.00e-31	128.00
IUUC-Dno-029409	Dasypus novemcinctus	29.71	7.00e-34	139.00
IUUC-Dor-030438	Dipodomys ordii	34.50	1.00e-21	98.20
IUUC-Eca-033479	Equus caballus	29.78	2.00e-33	137.00
IUUC-Fca-036320	Felis catus	28.64	2.00e-32	134.00
IUUC-Fal-037029	Ficedula albicollis	29.63	9.00e-34	138.00
IUUC-Gmo-039228	Gadus morhua	30.81	5.00e-30	125.00
IUUC-Gga-040527	Gallus gallus	29.41	5.00e-34	139.00
IUUC-Gac-042406	Gasterosteus aculeatus	32.18	3.00e-29	123.00
IUUC-Ggo-045598	Gorilla gorilla	28.57	5.00e-32	132.00
IUUC-Hsa-046598	Homo sapiens	28.81	1.00e-32	134.00
IUUC-Hvu-047146	Hordeum vulgare	39.31	2.00e-49	191.00
IUUC-Itr-047951	Ictidomys tridecemlineatus	28.81	1.00e-35	145.00
IUUC-Lch-050536	Latimeria chalumnae	30.38	8.00e-31	128.00
IUUC-Lpe-050703	Leersia perrieri	41.83	1.00e-49	191.00
IUUC-Loc-051814	Lepisosteus oculatus	30.81	6.00e-31	129.00
IUUC-Laf-053732	Loxodonta africana	29.09	3.00e-33	137.00
IUUC-Mcc-054661	Macaca mulatta	28.81	5.00e-33	135.00
IUUC-Mga-059551	Meleagris gallopavo	29.02	1.00e-34	141.00
IUUC-Mmr-061747	Microcebus murinus	29.79	4.00e-32	132.00
IUUC-Mdo-062220	Monodelphis domestica	29.16	5.00e-35	142.00
IUUC-Mmu-063582	Mus musculus	30.40	6.00e-36	145.00
IUUC-Mpu-066339	Mustela putorius furo	28.23	1.00e-32	135.00
IUUC-Mlu-067511	Myotis lucifugus	30.02	1.00e-32	134.00
IUUC-Nle-069252	Nomascus leucogenys	29.05	3.00e-33	136.00
IUUC-Opr-070969	Ochotona princeps	30.05	2.00e-32	134.00
IUUC-Ont-071786	Oreochromis niloticus	28.54	2.00e-31	130.00
IUUC-Oan-073656	Ornithorhynchus anatinus	29.11	2.00e-31	130.00
IUUC-Ocu-074704	Oryctolagus cuniculus	29.46	2.00e-32	134.00
IUUC-Oba-075094	Oryza barthii	41.73	8.00e-52	199.00
IUUC-Obr-076743	Oryza brachyantha	42.64	5.00e-49	189.00
IUUC-Ogl-077739	Oryza glaberrima	42.48	4.00e-52	199.00
IUUC-Ogu-078851	Oryza glumaepatula	42.48	5.00e-52	199.00
IUUC-Oin-079402	Oryza indica	42.48	6.00e-52	199.00
IUUC-Olo-080431	Oryza longistaminata	42.48	4.00e-52	199.00
IUUC-Ome-081580	Oryza meridionalis	42.11	2.00e-52	200.00
IUUC-Oni-082644	Oryza nivara	42.48	6.00e-52	199.00
IUUC-Opu-083452	Oryza punctata	41.83	3.00e-52	200.00
IUUC-Oru-084546	Oryza rufipogon	42.48	7.00e-52	199.00
IUUC-Osa-085858	Oryza sativa	42.48	6.00e-52	199.00
IUUC-Ola-087238	Oryzias latipes	30.41	3.00e-32	133.00
IUUC-Oga-088713	Otolemur garnettii	28.95	2.00e-32	134.00
IUUC-Oar-089887	Ovis aries	29.15	7.00e-33	135.00
IUUC-Ptr-091670	Pan troglodytes	28.57	7.00e-32	132.00
IUUC-Pan-092293	Papio anubis	28.81	5.00e-33	135.00
IUUC-Psi-093101	Pelodiscus sinensis	27.21	8.00e-31	128.00
IUUC-Ppa-095622	Physcomitrella patens	32.86	3.00e-43	170.00
IUUC-Pfo-097202	Poecilia formosa	29.93	1.00e-30	128.00
IUUC-Pab-098539	Pongo abelii	30.05	5.00e-31	129.00
IUUC-Rno-105237	Rattus norvegicus	29.76	2.00e-34	140.00
IUUC-Sha-106889	Sarcophilus harrisii	30.64	2.00e-32	134.00
IUUC-Stu-112820	Solanum tuberosum	48.22	5.00e-92	332.00
IUUC-Sar-113530	Sorex araneus	28.74	9.00e-33	135.00
IUUC-Ssc-116091	Sus scrofa	28.84	2.00e-32	134.00
IUUC-Tgu-116907	Taeniopygia guttata	31.98	5.00e-34	139.00
IUUC-Tru-118640	Takifugu rubripes	31.89	3.00e-34	140.00
IUUC-Tni-120015	Tetraodon nigroviridis	30.13	3.00e-30	127.00
IUUC-Tae-125785	Triticum aestivum	36.06	7.00e-46	179.00
IUUC-Tbe-128041	Tupaia belangeri	35.68	2.00e-24	107.00
IUUC-Ttr-128271	Tursiops truncatus	30.12	6.00e-34	139.00
IUUC-Vpa-130674	Vicugna pacos	28.84	2.00e-32	134.00
IUUC-Xtr-131869	Xenopus tropicalis	30.29	2.00e-35	144.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence