iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Eca-033512

UUCD1 version

UUC-EqC-00901

Ensembl Protein ID

ENSECAP00000012268.1

UniProt Accession

F7DNP2; F7DNP2_HORSE

Protein Name

Uncharacterized protein

Gene Name

STUB1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000014495.1	ENSECAT00000015282.1	ENSECAP00000012268.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/U-box	6.60e-27	93.6	173	246

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/U-box

   S: 1    evpeeflCpIslelMrdPvvlpsGitydrssIekwlasggktcPvtrqplteedlvPnltlrrliqawceenss 74
           ++p+++++ Is+elMr+P+++psGitydr+ Ie++l++ g+ +Pvtr+plt+e+l+Pnl+++++i+a+++en++
   Q: 173  DIPDYLCGKISFELMREPCITPSGITYDRKDIEEHLQRVGHFDPVTRSPLTQEQLIPNLAMKEVIDAFISENGW 246
           69********************************************************************9986 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

TRNPLVAVYY TNRALCYLKM QQHEQALADC RRALELDGQS VKAHFFLGQC QLEMESYDEA 60
IANLQRAYNL AKEQRLNFGD DIPSALRIAK KKRWNSIEER RIHQESELHS YLTRLITAER 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACCCGGAATC CCCTGGTGGC AGTGTATTAC ACCAACCGGG CACTGTGCTA CCTGAAGATG 60
CAGCAGCACG AGCAGGCCCT GGCCGACTGC CGGCGCGCCC TGGAGCTGGA TGGCCAGTCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0802--TPR repeat

Interpro

IPR023114--Elongated_TPR_rpt_dom
IPR013026--TPR-contain_dom
IPR011990--TPR-like_helical_dom
IPR019734--TPR_repeat
IPR003613--Ubox_domain
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50005--TPR
PS50293--TPR_REGION
PS51698--U_BOX

Pfam

PF04564--U-box

SMART

SM00028--TPR
SM00504--Ubox

Gene Ontology

GO:0005829--C:cytosol
GO:0005783--C:endoplasmic reticulum
GO:0070062--C:extracellular exosome
GO:0042405--C:nuclear inclusion body
GO:0005654--C:nucleoplasm
GO:0000151--C:ubiquitin ligase complex
GO:0030018--C:Z disc
GO:1904264--F:ubiquitin protein ligase activity involved in ERAD pathway
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0071218--P:cellular response to misfolded protein
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0006515--P:misfolded or incompletely synthesized protein catabolic process
GO:0032091--P:negative regulation of protein binding
GO:0030512--P:negative regulation of transforming growth factor beta receptor signaling pathway
GO:0090035--P:positive regulation of chaperone-mediated protein complex assembly
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0051443--P:positive regulation of ubiquitin-protein transferase activity
GO:0051865--P:protein autoubiquitination
GO:0070534--P:protein K63-linked ubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031943--P:regulation of glucocorticoid metabolic process
GO:0031647--P:regulation of protein stability
GO:0030579--P:ubiquitin-dependent SMAD protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000537	Aegilops tauschii	36.84	3.00e-38	151.00
IUUC-Aml-001350	Ailuropoda melanoleuca	98.80	5.00e-148	516.00
IUUC-Atr-003168	Amborella trichopoda	35.85	3.00e-31	128.00
IUUC-Apl-003736	Anas platyrhynchos	88.45	2.00e-132	464.00
IUUC-Aca-004751	Anolis carolinensis	87.25	7.00e-128	449.00
IUUC-Aly-006292	Arabidopsis lyrata	34.14	2.00e-38	152.00
IUUC-Ath-007012	Arabidopsis thaliana	32.39	5.00e-37	147.00
IUUC-Acl-008025	Aspergillus clavatus	29.80	3.00e-30	125.00
IUUC-Afl-008721	Aspergillus flavus	29.57	3.00e-27	115.00
IUUC-Afu-008853	Aspergillus fumigatus	30.89	2.00e-29	122.00
IUUC-Ani-009349	Aspergillus nidulans	31.58	6.00e-30	124.00
IUUC-Ang-009674	Aspergillus niger	31.66	1.00e-26	113.00
IUUC-Aor-010014	Aspergillus oryzae	29.57	3.00e-27	115.00
IUUC-Ate-010467	Aspergillus terreus	28.14	7.00e-21	94.00
IUUC-Ame-011215	Astyanax mexicanus	58.96	2.00e-79	288.00
IUUC-Bgr-011971	Blumeria graminis	29.53	4.00e-20	91.70
IUUC-Bta-013025	Bos taurus	97.98	2.00e-145	508.00
IUUC-Bci-013945	Botrytis cinerea	39.51	7.00e-15	74.30
IUUC-Bdi-014483	Brachypodium distachyon	40.16	2.00e-42	165.00
IUUC-Bol-015676	Brassica oleracea	35.08	4.00e-40	158.00
IUUC-Bra-017897	Brassica rapa	32.54	1.00e-29	122.00
IUUC-Cel-018323	Caenorhabditis elegans	42.68	1.00e-50	192.00
IUUC-Cja-019657	Callithrix jacchus	96.40	2.00e-145	507.00
IUUC-Cfa-020470	Canis familiaris	98.70	1.00e-135	474.00
IUUC-Cpo-022033	Cavia porcellus	98.00	3.00e-147	513.00
IUUC-Cre-022896	Chlamydomonas reinhardtii	26.44	3.00e-22	98.60
IUUC-Csa-023038	Chlorocebus sabaeus	97.60	7.00e-139	486.00
IUUC-Cin-025381	Ciona intestinalis	54.40	2.00e-80	291.00
IUUC-Cgl-026524	Colletotrichum gloeosporioides	31.08	8.00e-33	133.00
IUUC-Dre-027610	Danio rerio	80.00	1.00e-120	425.00
IUUC-Dno-030087	Dasypus novemcinctus	96.80	6.00e-146	509.00
IUUC-Dor-031029	Dipodomys ordii	90.40	8.00e-129	452.00
IUUC-Dse-031275	Dothistroma septosporum	30.30	2.00e-21	95.90
IUUC-Dme-031856	Drosophila melanogaster	58.23	1.00e-84	306.00
IUUC-Ete-033087	Echinops telfairi	93.15	3.00e-120	424.00
IUUC-Eeu-034763	Erinaceus europaeus	92.93	8.00e-99	352.00
IUUC-Fca-036460	Felis catus	98.40	8.00e-147	512.00
IUUC-Fal-037441	Ficedula albicollis	88.05	2.00e-131	461.00
IUUC-Fox-038028	Fusarium oxysporum	30.94	1.00e-33	136.00
IUUC-Fso-038323	Fusarium solani	32.53	6.00e-25	107.00
IUUC-Gmo-038511	Gadus morhua	78.40	2.00e-115	408.00
IUUC-Ggr-039964	Gaeumannomyces graminis	32.95	4.00e-23	101.00
IUUC-Gga-040854	Gallus gallus	88.84	3.00e-132	464.00
IUUC-Gac-042175	Gasterosteus aculeatus	77.60	4.00e-112	397.00
IUUC-Gma-044046	Glycine max	36.55	4.00e-39	154.00
IUUC-Ggo-044512	Gorilla gorilla	97.60	7.00e-139	486.00
IUUC-Hsa-046872	Homo sapiens	97.60	7.00e-139	486.00
IUUC-Hvu-047661	Hordeum vulgare	35.77	2.00e-35	142.00
IUUC-Itr-048871	Ictidomys tridecemlineatus	97.60	2.00e-146	511.00
IUUC-Lch-049988	Latimeria chalumnae	83.67	2.00e-116	411.00
IUUC-Lpe-050693	Leersia perrieri	35.37	5.00e-39	154.00
IUUC-Loc-052195	Lepisosteus oculatus	79.76	3.00e-116	410.00
IUUC-Lma-053207	Leptosphaeria maculans	30.07	4.00e-23	103.00
IUUC-Laf-054584	Loxodonta africana	96.80	3.00e-146	510.00
IUUC-Mcc-054689	Macaca mulatta	97.60	7.00e-139	486.00
IUUC-Meu-055998	Macropus eugenii	90.91	8.00e-63	233.00
IUUC-Mor-057116	Magnaporthe oryzae	32.14	1.00e-32	133.00
IUUC-Mtr-057684	Medicago truncatula	33.61	2.00e-34	139.00
IUUC-Mga-059332	Meleagris gallopavo	88.84	4.00e-132	463.00
IUUC-Mmr-061377	Microcebus murinus	97.60	1.00e-138	485.00
IUUC-Mdo-061963	Monodelphis domestica	91.70	3.00e-127	447.00
IUUC-Mmu-063146	Mus musculus	97.60	3.00e-138	484.00
IUUC-Mac-064932	Musa acuminata	33.98	1.00e-27	115.00
IUUC-Mpu-066418	Mustela putorius furo	98.80	4.00e-148	516.00
IUUC-Mlu-067066	Myotis lucifugus	98.40	7.00e-148	516.00
IUUC-Nfi-068601	Neosartorya fischeri	30.89	3.00e-29	122.00
IUUC-Ncr-068761	Neurospora crassa	41.67	4.00e-17	81.60
IUUC-Nle-069374	Nomascus leucogenys	97.60	7.00e-139	486.00
IUUC-Opr-070765	Ochotona princeps	91.80	8.00e-102	362.00
IUUC-Ont-071996	Oreochromis niloticus	82.00	3.00e-115	407.00
IUUC-Oba-075967	Oryza barthii	36.44	5.00e-40	157.00
IUUC-Obr-076440	Oryza brachyantha	34.98	2.00e-31	132.00
IUUC-Ogl-076959	Oryza glaberrima	36.69	5.00e-40	157.00
IUUC-Ogu-078247	Oryza glumaepatula	36.69	6.00e-40	157.00
IUUC-Oin-079616	Oryza indica	36.69	5.00e-40	157.00
IUUC-Olo-081083	Oryza longistaminata	31.85	3.00e-29	122.00
IUUC-Ome-081935	Oryza meridionalis	29.39	2.00e-20	95.10
IUUC-Oni-082535	Oryza nivara	36.69	6.00e-40	157.00
IUUC-Opu-083794	Oryza punctata	36.59	2.00e-39	155.00
IUUC-Oru-085166	Oryza rufipogon	36.69	6.00e-40	157.00
IUUC-Osa-085936	Oryza sativa	36.89	9.00e-13	66.60
IUUC-Ola-087081	Oryzias latipes	80.00	4.00e-119	420.00
IUUC-Olu-087790	Ostreococcus lucimarinus	30.83	1.00e-25	109.00
IUUC-Oga-088331	Otolemur garnettii	98.00	6.00e-140	489.00
IUUC-Oar-089987	Ovis aries	95.31	2.00e-142	498.00
IUUC-Ptr-090855	Pan troglodytes	97.60	7.00e-139	486.00
IUUC-Pan-092801	Papio anubis	91.20	7.00e-137	479.00
IUUC-Psi-093393	Pelodiscus sinensis	87.65	1.00e-131	461.00
IUUC-Pma-094680	Petromyzon marinus	69.32	2.00e-101	361.00
IUUC-Pno-094913	Phaeosphaeria nodorum	33.59	4.00e-29	121.00
IUUC-Ppa-095508	Physcomitrella patens	32.62	2.00e-38	152.00
IUUC-Pfo-096850	Poecilia formosa	79.60	5.00e-112	397.00
IUUC-Pab-097963	Pongo abelii	97.60	7.00e-139	486.00
IUUC-Pop-098805	Populus trichocarpa	43.88	6.00e-25	107.00
IUUC-Pca-100788	Procavia capensis	97.20	6.00e-147	513.00
IUUC-Ppe-101221	Prunus persica	36.14	4.00e-40	157.00
IUUC-Pva-103076	Pteropus vampyrus	98.00	9.00e-147	512.00
IUUC-Pte-104237	Pyrenophora teres	31.75	1.00e-27	117.00
IUUC-Pyt-104468	Pyrenophora triticirepentis	31.75	8.00e-28	117.00
IUUC-Rno-105204	Rattus norvegicus	97.60	1.00e-138	485.00
IUUC-Sha-106579	Sarcophilus harrisii	87.11	2.00e-127	447.00
IUUC-Smo-109525	Selaginella moellendorffii	35.69	1.00e-37	150.00
IUUC-Sit-110665	Setaria italica	36.18	1.00e-39	156.00
IUUC-Sly-111473	Solanum lycopersicum	38.10	1.00e-40	159.00
IUUC-Stu-112353	Solanum tuberosum	36.80	1.00e-38	152.00
IUUC-Sbi-114250	Sorghum bicolor	36.69	4.00e-40	157.00
IUUC-Ssc-115416	Sus scrofa	98.00	3.00e-147	513.00
IUUC-Tgu-117272	Taeniopygia guttata	94.44	4.00e-57	212.00
IUUC-Tru-117777	Takifugu rubripes	80.40	8.00e-114	402.00
IUUC-Tni-120572	Tetraodon nigroviridis	81.20	6.00e-114	403.00
IUUC-Tca-121149	Theobroma cacao	39.76	1.00e-45	176.00
IUUC-Tre-122230	Trichoderma reesei	31.73	2.00e-26	112.00
IUUC-Tvi-122678	Trichoderma virens	34.92	6.00e-37	147.00
IUUC-Tae-124860	Triticum aestivum	36.07	4.00e-39	154.00
IUUC-Tur-126009	Triticum urartu	35.51	2.00e-37	149.00
IUUC-Tme-126948	Tuber melanosporum	36.44	8.00e-37	146.00
IUUC-Ttr-129031	Tursiops truncatus	98.80	1.00e-147	515.00
IUUC-Vda-130023	Verticillium dahliae	32.23	3.00e-33	135.00
IUUC-Vvi-131091	Vitis vinifera	40.80	5.00e-25	106.00
IUUC-Xtr-132871	Xenopus tropicalis	84.06	8.00e-116	409.00
IUUC-Xma-134220	Xiphophorus maculatus	79.60	7.00e-112	396.00
IUUC-Yli-134462	Yarrowia lipolytica	28.46	1.00e-23	103.00
IUUC-Zma-135773	Zea mays	37.20	6.00e-41	160.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence