iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGALG00000016849.6	ENSGALT00000049451.2	ENSGALP00000058399.2
ENSGALG00000016849.6	ENSGALT00000058257.2	ENSGALP00000052488.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	5.30e-09	36.5	214	261

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCek..Cr.ewfHpaClklsveeelpnsekwiCpkCrs 53
           ++C +C + + +e  ++ C++  C  ewfH+ C++l+    +p+ + w+CpkCr 
   Q: 214  TYC-LCNQVSYGE--MIGCDNdeCPiEWFHFSCVGLN---HKPKGK-WYCPKCRG 261
           69*.*******99..******9**99***********...999997.******85 PP

Organism

Gallus gallus

Protein Sequence
(Fasta)

RMKMLSPANG EQLHLVNYVE DYLDSIESLP FDLQRNVSLM REIDAKYQEI LKDLDDYYEK 60
FKRENDAVQK RRMLHCIQRA LIRSQELGDE KIQIVSQMVE LVENRSRQVD SHVELFETCQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGGATGAAAA TGTTGAGTCC TGCAAACGGA GAGCAGCTGC ACCTCGTGAA CTACGTGGAG 60
GATTATCTGG ACTCCATCGA GTCTCTGCCC TTCGATCTGC AGAGAAATGT CTCCTTGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR028643--ING1
IPR028651--ING_fam
IPR024610--ING_N_histone_binding
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF12998--ING

SMART

SM01408--ING
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0008270--F:zinc ion binding
GO:0016569--P:covalent chromatin modification
GO:0008285--P:negative regulation of cell proliferation
GO:0010941--P:regulation of cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001945	Ailuropoda melanoleuca	93.19	4.00e-129	453.00
IUUC-Apl-003910	Anas platyrhynchos	98.58	3.00e-138	483.00
IUUC-Aca-004874	Anolis carolinensis	94.64	8.00e-130	455.00
IUUC-Aly-005815	Arabidopsis lyrata	80.00	1.00e-28	119.00
IUUC-Ame-011262	Astyanax mexicanus	67.93	2.00e-96	345.00
IUUC-Bta-013507	Bos taurus	88.46	2.00e-92	331.00
IUUC-Cja-018925	Callithrix jacchus	89.96	2.00e-123	434.00
IUUC-Cfa-020947	Canis familiaris	93.19	2.00e-128	451.00
IUUC-Cpo-022286	Cavia porcellus	89.83	7.00e-99	353.00
IUUC-Csa-023825	Chlorocebus sabaeus	89.61	6.00e-123	432.00
IUUC-Cho-024577	Choloepus hoffmanni	92.70	5.00e-100	356.00
IUUC-Cne-027005	Cryptococcus neoformans	47.76	7.00e-16	77.80
IUUC-Dre-028562	Danio rerio	59.56	2.00e-75	275.00
IUUC-Dno-029834	Dasypus novemcinctus	94.27	8.00e-130	456.00
IUUC-Dor-030315	Dipodomys ordii	89.32	1.00e-108	386.00
IUUC-Ete-032408	Echinops telfairi	89.79	3.00e-95	341.00
IUUC-Eca-034244	Equus caballus	92.31	8.00e-102	362.00
IUUC-Fca-035391	Felis catus	87.26	3.00e-108	384.00
IUUC-Fal-036838	Ficedula albicollis	97.51	6.00e-137	479.00
IUUC-Fox-037925	Fusarium oxysporum	69.57	1.00e-19	90.50
IUUC-Gmo-038748	Gadus morhua	55.26	6.00e-77	280.00
IUUC-Gac-041996	Gasterosteus aculeatus	63.96	8.00e-97	346.00
IUUC-Ggo-045481	Gorilla gorilla	86.44	8.00e-96	343.00
IUUC-Hsa-046170	Homo sapiens	86.44	6.00e-96	343.00
IUUC-Itr-048440	Ictidomys tridecemlineatus	94.44	3.00e-103	367.00
IUUC-Lch-050397	Latimeria chalumnae	89.61	7.00e-126	442.00
IUUC-Loc-052038	Lepisosteus oculatus	80.23	7.00e-101	359.00
IUUC-Laf-054126	Loxodonta africana	94.62	2.00e-130	457.00
IUUC-Mcc-055031	Macaca mulatta	86.81	2.00e-95	342.00
IUUC-Meu-056248	Macropus eugenii	93.70	2.00e-105	374.00
IUUC-Mga-059217	Meleagris gallopavo	98.71	2.00e-108	384.00
IUUC-Mmr-061581	Microcebus murinus	93.83	9.00e-108	382.00
IUUC-Mdo-062452	Monodelphis domestica	95.34	2.00e-132	464.00
IUUC-Mmu-063412	Mus musculus	92.47	7.00e-127	446.00
IUUC-Mpu-066479	Mustela putorius furo	92.31	9.00e-102	362.00
IUUC-Mlu-067586	Myotis lucifugus	79.36	2.00e-117	414.00
IUUC-Nle-069122	Nomascus leucogenys	89.25	3.00e-122	430.00
IUUC-Opr-070835	Ochotona princeps	83.69	3.00e-83	301.00
IUUC-Ont-071606	Oreochromis niloticus	61.11	9.00e-91	326.00
IUUC-Oan-073023	Ornithorhynchus anatinus	92.47	1.00e-125	442.00
IUUC-Ocu-073779	Oryctolagus cuniculus	87.50	1.00e-93	335.00
IUUC-Ola-086891	Oryzias latipes	65.36	3.00e-97	347.00
IUUC-Oga-087954	Otolemur garnettii	92.11	6.00e-127	446.00
IUUC-Oar-090006	Ovis aries	89.96	2.00e-123	434.00
IUUC-Ptr-090589	Pan troglodytes	89.61	6.00e-123	432.00
IUUC-Pan-091896	Papio anubis	86.81	2.00e-95	342.00
IUUC-Psi-093266	Pelodiscus sinensis	96.09	2.00e-134	471.00
IUUC-Pma-094265	Petromyzon marinus	71.95	1.00e-34	138.00
IUUC-Pfo-097531	Poecilia formosa	61.29	1.00e-93	336.00
IUUC-Pab-098253	Pongo abelii	89.61	1.00e-122	432.00
IUUC-Pva-102753	Pteropus vampyrus	82.63	5.00e-91	327.00
IUUC-Rno-105964	Rattus norvegicus	91.03	2.00e-90	324.00
IUUC-Sha-107270	Sarcophilus harrisii	95.34	1.00e-131	462.00
IUUC-Tgu-116822	Taeniopygia guttata	97.85	5.00e-136	476.00
IUUC-Tru-118262	Takifugu rubripes	56.49	2.00e-77	282.00
IUUC-Tni-119980	Tetraodon nigroviridis	61.07	1.00e-83	302.00
IUUC-Tre-121950	Trichoderma reesei	64.29	3.00e-19	90.50
IUUC-Tvi-122341	Trichoderma virens	62.50	3.00e-16	77.00
IUUC-Ttr-128672	Tursiops truncatus	90.21	3.00e-99	354.00
IUUC-Xtr-132200	Xenopus tropicalis	86.38	6.00e-119	419.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence