iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOARG00000009374.1	ENSOART00000010204.1	ENSOARP00000010058.1
ENSOARG00000009374.1	ENSOART00000010206.1	ENSOARP00000010060.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/SCF/F-box	4.50e-06	27.0	202	249

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/SCF/F-box

   S: 99   daglldrlpeeilveilklldkeellraarvcrrwqelasqkalwktv 146
           +++ +++lp e++v+i+++l+++el+r+++v+ +w++la++ +lwk++
   Q: 202  QSTGISHLPPEVMVSIFSYLNPQELCRCSQVSTKWSQLAKTGSLWKHL 249
           5566899*********************************9****987 PP

Organism

Ovis aries

Protein Sequence
(Fasta)

PFPSRACTFL CPDVQDYHIV LLKGLHSRKL SKTNFSNNND FRALLQSLYA TFKEFKMHEQ 60
IENEYIIGLL QQRSQTIYNV HSDNKLSEML SLFEKGLKNV KNEYEQLNYA KQLKERLEAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGGACTGT GCGACAGGAG ATACACGCAC AGGTCTCTGG CACAGGTACG GGAAGCGTCT 60
ACATGTCTGG GTGGTAGTGC AGGGCTTCTG AGAAACTGGA TAGAGCTCTG CAATGGTGGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001810--F-box_dom
IPR032675--L_dom-like
IPR001611--Leu-rich_rpt
IPR006553--Leu-rich_rpt_Cys-con_subtyp

PROSITE

PS50181--FBOX

Pfam

PF12937--F-box-like
PF13516--LRR_6

SMART

SM00256--FBOX
SM00367--LRR_CC

Gene Ontology

GO:0048471--C:perinuclear region of cytoplasm
GO:0019005--C:SCF ubiquitin ligase complex
GO:0005506--F:iron ion binding
GO:0055072--P:iron ion homeostasis
GO:1903364--P:positive regulation of cellular protein catabolic process
GO:0016567--P:protein ubiquitination
GO:0031146--P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002319	Ailuropoda melanoleuca	96.11	0.00e+00	1212.00
IUUC-Apl-003755	Anas platyrhynchos	80.42	0.00e+00	1011.00
IUUC-Aca-004798	Anolis carolinensis	74.93	0.00e+00	1005.00
IUUC-Ath-007384	Arabidopsis thaliana	33.33	1.70e-02	33.10
IUUC-Ame-011091	Astyanax mexicanus	58.12	0.00e+00	728.00
IUUC-Bta-013204	Bos taurus	98.95	0.00e+00	1258.00
IUUC-Bol-015838	Brassica oleracea	36.23	5.00e-04	38.10
IUUC-Cja-019594	Callithrix jacchus	93.81	0.00e+00	1021.00
IUUC-Cfa-020965	Canis familiaris	93.35	0.00e+00	1204.00
IUUC-Cpo-021308	Cavia porcellus	89.31	0.00e+00	1174.00
IUUC-Csa-023865	Chlorocebus sabaeus	91.76	0.00e+00	1243.00
IUUC-Cho-024778	Choloepus hoffmanni	82.95	1.00e-164	573.00
IUUC-Dre-027628	Danio rerio	52.97	8.00e-166	577.00
IUUC-Dno-029899	Dasypus novemcinctus	92.10	0.00e+00	1220.00
IUUC-Dor-031105	Dipodomys ordii	77.48	0.00e+00	995.00
IUUC-Ete-032314	Echinops telfairi	87.03	0.00e+00	1082.00
IUUC-Eca-033797	Equus caballus	95.44	0.00e+00	1162.00
IUUC-Eeu-034811	Erinaceus europaeus	85.04	0.00e+00	888.00
IUUC-Fca-036516	Felis catus	95.18	0.00e+00	1181.00
IUUC-Fal-036824	Ficedula albicollis	78.18	0.00e+00	941.00
IUUC-Gga-040271	Gallus gallus	78.35	0.00e+00	1029.00
IUUC-Gac-041399	Gasterosteus aculeatus	60.11	0.00e+00	755.00
IUUC-Ggo-044415	Gorilla gorilla	91.91	0.00e+00	1246.00
IUUC-Hsa-047001	Homo sapiens	91.91	0.00e+00	1259.00
IUUC-Itr-048356	Ictidomys tridecemlineatus	92.40	0.00e+00	1026.00
IUUC-Lch-049897	Latimeria chalumnae	63.04	0.00e+00	795.00
IUUC-Loc-052162	Lepisosteus oculatus	63.65	0.00e+00	818.00
IUUC-Laf-054031	Loxodonta africana	91.18	0.00e+00	1204.00
IUUC-Mcc-054680	Macaca mulatta	92.05	0.00e+00	1248.00
IUUC-Meu-056199	Macropus eugenii	82.83	4.00e-104	372.00
IUUC-Mga-059675	Meleagris gallopavo	80.75	0.00e+00	1026.00
IUUC-Mmr-061694	Microcebus murinus	91.62	0.00e+00	1236.00
IUUC-Mdo-062900	Monodelphis domestica	86.27	0.00e+00	1157.00
IUUC-Mmu-063178	Mus musculus	88.87	0.00e+00	1195.00
IUUC-Mpu-066584	Mustela putorius furo	92.77	0.00e+00	1205.00
IUUC-Mlu-067859	Myotis lucifugus	94.43	0.00e+00	1188.00
IUUC-Nle-069172	Nomascus leucogenys	92.34	0.00e+00	1223.00
IUUC-Opr-070992	Ochotona princeps	88.76	0.00e+00	982.00
IUUC-Ont-072577	Oreochromis niloticus	60.00	0.00e+00	752.00
IUUC-Oan-072870	Ornithorhynchus anatinus	84.16	0.00e+00	899.00
IUUC-Ocu-074849	Oryctolagus cuniculus	92.76	0.00e+00	1194.00
IUUC-Ola-087146	Oryzias latipes	58.01	0.00e+00	737.00
IUUC-Oga-088307	Otolemur garnettii	93.98	0.00e+00	1218.00
IUUC-Ptr-091049	Pan troglodytes	92.20	0.00e+00	1250.00
IUUC-Pan-091995	Papio anubis	91.91	0.00e+00	1246.00
IUUC-Psi-093154	Pelodiscus sinensis	79.43	0.00e+00	990.00
IUUC-Pma-094334	Petromyzon marinus	46.35	7.00e-139	487.00
IUUC-Pfo-096154	Poecilia formosa	59.21	0.00e+00	729.00
IUUC-Pab-098264	Pongo abelii	94.73	0.00e+00	1240.00
IUUC-Pca-100884	Procavia capensis	69.36	0.00e+00	870.00
IUUC-Pva-102114	Pteropus vampyrus	92.35	0.00e+00	1234.00
IUUC-Rno-105392	Rattus norvegicus	89.60	0.00e+00	1197.00
IUUC-Sha-106508	Sarcophilus harrisii	86.42	0.00e+00	1160.00
IUUC-Sar-113107	Sorex araneus	90.14	0.00e+00	833.00
IUUC-Ssc-115489	Sus scrofa	93.21	0.00e+00	1201.00
IUUC-Tgu-116734	Taeniopygia guttata	78.27	0.00e+00	991.00
IUUC-Tru-117632	Takifugu rubripes	59.38	0.00e+00	739.00
IUUC-Tsy-119400	Tarsius syrichta	93.21	0.00e+00	1201.00
IUUC-Tni-120602	Tetraodon nigroviridis	58.04	0.00e+00	751.00
IUUC-Tbe-127833	Tupaia belangeri	91.28	3.00e-180	624.00
IUUC-Ttr-129289	Tursiops truncatus	94.71	0.00e+00	740.00
IUUC-Vpa-130253	Vicugna pacos	95.86	0.00e+00	642.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence