iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ocu-074683

Ensembl Protein ID

ENSOCUP00000020100.1

UniProt Accession

Q95MN1; Q95MN1_RABIT

Genbank Protein ID

AAK60125.1

Protein Name

p40-phox

Genbank Nucleotide ID

AAGW02061065

Gene Name

NCF4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOCUG00000021337.2	ENSOCUT00000029379.2	ENSOCUP00000020100.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.40e-12	46.2	175	228
ULD/UDP/UFD/PB1	3.20e-20	72.1	237	330

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
            ++l+d++++++ eLt+k+Gdv++++     +++Wl+g  +l+g  G+fP  Fv+ ++
   Q: 175  AEALFDFTGNSKLELTFKAGDVIFLL--SRINKDWLEG--TLRGATGIFPFSFVKIIK 228
           689***********************..999*******..8*************9876 PP

ULD/UDP/UFD/PB1

   S: 1    tvrvkvsykgeirs.......faldlekpgkfedLlkavrtltelknsevalkYeDedGDlvtlksDedldkavslla...skksll.. 77
           t++++++y++++ s       +++dl+++++f+dLl+++r+  e++++++al+Y+D+ GDlv+l sDed+  +v++++   s+k+l+  
   Q: 237  TNWLRCYYYEDTVStiikdiaVEEDLSSTPLFKDLLELMRR--EFQREDIALNYRDAQGDLVRLLSDEDVGLMVRQARglpSQKRLFpw 323
           589*********99***************************..********************************************99 PP
   S: 78   rlliqkk 84
           +l++++k
   Q: 324  KLHVTQK 330
           9*99985 PP

Organism

Oryctolagus cuniculus

Protein Sequence
(Fasta)

MALVQQLRAE SDFEQLPDDV AVSANIADIE EKRGFTSHFV FVIEVKTKGG CKYLIYRRYR 60
QFHALQSRLE ERFGPDGKGG APTCSLPTLP AKVYVGVKQE IAEMRIPALN AYMKHLLSLP 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCCTCAGGGA CAACAGGCGA GGTGCAGGCC AGCACTGCAG GCCCAGGGAA TGGCTTGAGC 60
AAAGCTTAGG TTGGGTTTAA GGGACCGGAG GGGGCGTGGC CTGCCCGGGA GCAGGTGCGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000919--NCF_P40
IPR000270--PB1_dom
IPR001683--Phox
IPR001452--SH3_domain

PROSITE

PS51745--PB1
PS50195--PX
PS50002--SH3

Pfam

PF00564--PB1
PF00787--PX
PF00018--SH3_1

PRINTS

PR00497--P40PHOX

SMART

SM00666--PB1
SM00312--PX
SM00326--SH3

Gene Ontology

GO:0005829--C:cytosol
GO:0010008--C:endosome membrane
GO:0043020--C:NADPH oxidase complex
GO:0032266--F:phosphatidylinositol-3-phosphate binding
GO:0016176--F:superoxide-generating NADPH oxidase activator activity

KEGG

ocu:100009359

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001675	Ailuropoda melanoleuca	86.76	2.00e-174	604.00
IUUC-Apl-003431	Anas platyrhynchos	66.47	9.00e-132	462.00
IUUC-Aca-005176	Anolis carolinensis	70.62	7.00e-134	469.00
IUUC-Ame-011492	Astyanax mexicanus	59.10	2.00e-113	401.00
IUUC-Bta-013434	Bos taurus	86.76	2.00e-163	567.00
IUUC-Cja-019788	Callithrix jacchus	88.53	9.00e-180	622.00
IUUC-Cfa-021039	Canis familiaris	87.06	6.00e-170	589.00
IUUC-Cpo-021848	Cavia porcellus	86.18	4.00e-170	590.00
IUUC-Csa-023733	Chlorocebus sabaeus	89.83	8.00e-158	549.00
IUUC-Dre-027732	Danio rerio	55.87	4.00e-97	347.00
IUUC-Dno-029154	Dasypus novemcinctus	80.12	9.00e-157	545.00
IUUC-Eca-034062	Equus caballus	88.53	4.00e-173	600.00
IUUC-Eeu-035129	Erinaceus europaeus	69.23	3.00e-63	235.00
IUUC-Fca-036402	Felis catus	87.94	3.00e-177	613.00
IUUC-Fal-037105	Ficedula albicollis	67.06	6.00e-131	460.00
IUUC-Gmo-039144	Gadus morhua	47.95	3.00e-35	140.00
IUUC-Gga-040526	Gallus gallus	67.65	3.00e-132	464.00
IUUC-Ggo-044667	Gorilla gorilla	90.87	7.00e-137	479.00
IUUC-Hsa-045779	Homo sapiens	90.88	0.00e+00	640.00
IUUC-Itr-048385	Ictidomys tridecemlineatus	71.72	3.00e-129	454.00
IUUC-Lch-050264	Latimeria chalumnae	53.67	1.00e-113	402.00
IUUC-Loc-051887	Lepisosteus oculatus	54.65	1.00e-102	365.00
IUUC-Laf-054411	Loxodonta africana	80.36	9.00e-150	522.00
IUUC-Mcc-055835	Macaca mulatta	90.58	3.00e-178	617.00
IUUC-Meu-056875	Macropus eugenii	80.30	4.00e-91	327.00
IUUC-Mga-059737	Meleagris gallopavo	66.76	1.00e-130	459.00
IUUC-Mmr-061065	Microcebus murinus	86.61	2.00e-122	431.00
IUUC-Mdo-062598	Monodelphis domestica	81.23	3.00e-156	543.00
IUUC-Mmu-063643	Mus musculus	87.65	3.00e-177	613.00
IUUC-Mpu-066142	Mustela putorius furo	87.06	1.00e-177	615.00
IUUC-Mlu-067898	Myotis lucifugus	82.22	7.00e-42	160.00
IUUC-Nle-069935	Nomascus leucogenys	77.78	6.00e-147	513.00
IUUC-Opr-070204	Ochotona princeps	89.23	2.00e-139	488.00
IUUC-Ont-072261	Oreochromis niloticus	54.70	1.00e-103	369.00
IUUC-Oan-072846	Ornithorhynchus anatinus	76.43	8.00e-70	255.00
IUUC-Ola-086700	Oryzias latipes	55.56	4.00e-96	344.00
IUUC-Oga-087992	Otolemur garnettii	88.32	9.00e-175	605.00
IUUC-Oar-089828	Ovis aries	85.96	2.00e-161	561.00
IUUC-Pan-092264	Papio anubis	88.82	0.00e+00	628.00
IUUC-Psi-093800	Pelodiscus sinensis	67.65	1.00e-129	455.00
IUUC-Pfo-096677	Poecilia formosa	52.23	1.00e-85	310.00
IUUC-Pab-097920	Pongo abelii	90.00	0.00e+00	635.00
IUUC-Pca-100312	Procavia capensis	68.46	4.00e-92	330.00
IUUC-Pva-102113	Pteropus vampyrus	85.77	3.00e-131	461.00
IUUC-Rno-105777	Rattus norvegicus	87.06	5.00e-177	613.00
IUUC-Sha-106666	Sarcophilus harrisii	81.23	3.00e-163	567.00
IUUC-Ssc-116056	Sus scrofa	86.18	4.00e-176	610.00
IUUC-Tgu-116797	Taeniopygia guttata	67.65	6.00e-133	466.00
IUUC-Tru-117860	Takifugu rubripes	54.02	4.00e-98	350.00
IUUC-Tsy-119537	Tarsius syrichta	90.06	8.00e-85	306.00
IUUC-Tni-119946	Tetraodon nigroviridis	55.65	7.00e-99	353.00
IUUC-Tbe-127274	Tupaia belangeri	73.41	2.00e-103	368.00
IUUC-Ttr-129026	Tursiops truncatus	87.08	9.00e-108	382.00
IUUC-Xtr-131910	Xenopus tropicalis	52.94	2.00e-104	372.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence