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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063666
UUCD1 version UUC-MuM-00660
Ensembl Protein ID ENSMUSP00000043874.7
UniProt Accession F8WI37; F8WI37_MOUSE
Genbank Protein ID ENSMUSP00000043874
Protein Name Histone-lysine N-methyltransferase
Genbank Nucleotide ID AC116469
Gene Name Kmt2c; Mll3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000038056.15 ENSMUST00000174734.7 ENSMUSP00000133482.1
ENSMUSG00000038056.15 ENSMUST00000172556.7 ENSMUSP00000133941.1
ENSMUSG00000038056.15 ENSMUST00000045291.13 ENSMUSP00000043874.7
ENSMUSG00000038056.15 ENSMUST00000173073.7 ENSMUSP00000134442.1
ENSMUSG00000038056.15 ENSMUST00000173174.1 ENSMUSP00000133304.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
AREsitemiRTarBasemicroRNATRANSFAC
RepTarmiRNAMapRAID2
Protein-protein Interaction
HINT
Post-translational Modifications (PTMs)
CPLM
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 2.50e-25 89.5 952 1002
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggedek.slveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C vCg+ g++ +  l+ C++C +++Hp C+++++ + + ++  w C +C+
   Q: 952  DMCVVCGSFGQGAEgRLLACSQCGQCYHPYCVSIKITKVVLSK-GWRCLECT 1002
           79*********9999********************66666555.5******6 PP
   
Organism Mus musculus
Protein Sequence
(Fasta)
MSSEEDRSAE QQQPPPAPPE EPGAPAPSPA AADKRPRGRP RKDGASPFQR ARKKPRSRGK 60
STVEDEDSMD GLETTETENI VETEIKEQSV EEDAETEVDS SKQPVSALQR SVSEESANSL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063666|E3,PHD|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GAGTGCGCGC GCCCGCGCCG ATGTGTGTGA GTGCGTGTCC TGCTAGCTCC ATGTTGCCGC 60
CTCTCCCGGT ACCTGCTGCT GCTGCTGCTG CTCCCGGGGC TGCGGGAAAT GCGAGAGGCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063666|E3,PHD|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR000637--HMGI/Y_DNA-bd_CS
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS00354--HMGI_Y
PS50868--POST_SET
PS50280--SET
PS50016--ZF_PHD_2
PS50089--ZF_RING_2
Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET
SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00184--RING
SM00317--SET
Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding
GO:0006355--P:regulation of transcription, DNA-templated
KEGG mmu:231051
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-002314 Ailuropoda melanoleuca 83.14 0.00e+00 6832.00
IUUC-Apl-003311 Anas platyrhynchos 71.01 0.00e+00 5614.00
IUUC-Aca-004705 Anolis carolinensis 65.11 0.00e+00 5185.00
IUUC-Bta-012322 Bos taurus 80.02 0.00e+00 6464.00
IUUC-Cja-019983 Callithrix jacchus 84.75 0.00e+00 7190.00
IUUC-Cfa-020903 Canis familiaris 82.59 0.00e+00 6930.00
IUUC-Cpo-021732 Cavia porcellus 81.25 0.00e+00 6809.00
IUUC-Csa-023083 Chlorocebus sabaeus 82.43 0.00e+00 5313.00
IUUC-Cho-024469 Choloepus hoffmanni 76.86 0.00e+00 2075.00
IUUC-Dre-028110 Danio rerio 63.63 0.00e+00 1224.00
IUUC-Dor-030569 Dipodomys ordii 79.52 0.00e+00 4487.00
IUUC-Dme-031590 Drosophila melanogaster 33.40 3.00e-69 257.00
IUUC-Eca-033945 Equus caballus 82.20 0.00e+00 4917.00
IUUC-Fca-035922 Felis catus 81.33 0.00e+00 6646.00
IUUC-Gac-041896 Gasterosteus aculeatus 47.91 0.00e+00 1337.00
IUUC-Ggo-044812 Gorilla gorilla 82.37 0.00e+00 6952.00
IUUC-Hsa-046595 Homo sapiens 84.84 0.00e+00 7227.00
IUUC-Itr-048303 Ictidomys tridecemlineatus 84.70 0.00e+00 7003.00
IUUC-Lch-050086 Latimeria chalumnae 55.99 0.00e+00 2549.00
IUUC-Loc-052891 Lepisosteus oculatus 51.13 0.00e+00 2101.00
IUUC-Laf-054348 Loxodonta africana 78.93 0.00e+00 2905.00
IUUC-Mcc-054868 Macaca mulatta 85.04 0.00e+00 7114.00
IUUC-Meu-056322 Macropus eugenii 65.07 0.00e+00 1130.00
IUUC-Mga-059541 Meleagris gallopavo 70.27 0.00e+00 5495.00
IUUC-Mmr-061092 Microcebus murinus 81.97 0.00e+00 5314.00
IUUC-Mdo-062610 Monodelphis domestica 74.11 0.00e+00 2055.00
IUUC-Mpu-066366 Mustela putorius furo 80.66 0.00e+00 6333.00
IUUC-Mlu-068201 Myotis lucifugus 78.45 0.00e+00 3951.00
IUUC-Nle-069232 Nomascus leucogenys 81.99 0.00e+00 5238.00
IUUC-Opr-070625 Ochotona princeps 74.57 0.00e+00 1283.00
IUUC-Ont-072401 Oreochromis niloticus 56.52 0.00e+00 1038.00
IUUC-Oan-072945 Ornithorhynchus anatinus 70.22 0.00e+00 4092.00
IUUC-Ocu-074920 Oryctolagus cuniculus 80.16 0.00e+00 5134.00
IUUC-Ola-086436 Oryzias latipes 44.36 0.00e+00 1832.00
IUUC-Oga-088637 Otolemur garnettii 79.38 0.00e+00 4149.00
IUUC-Oar-089363 Ovis aries 77.99 0.00e+00 6282.00
IUUC-Ptr-091527 Pan troglodytes 84.79 0.00e+00 7227.00
IUUC-Pan-092102 Papio anubis 82.80 0.00e+00 6890.00
IUUC-Pma-094252 Petromyzon marinus 38.99 0.00e+00 633.00
IUUC-Pfo-096288 Poecilia formosa 46.24 0.00e+00 1280.00
IUUC-Pab-098241 Pongo abelii 84.37 0.00e+00 4582.00
IUUC-Pca-100103 Procavia capensis 79.10 0.00e+00 1541.00
IUUC-Pva-102238 Pteropus vampyrus 73.47 0.00e+00 2458.00
IUUC-Rno-105395 Rattus norvegicus 90.66 0.00e+00 1351.00
IUUC-Sha-106550 Sarcophilus harrisii 70.40 0.00e+00 4325.00
IUUC-Sar-113183 Sorex araneus 64.04 0.00e+00 674.00
IUUC-Tgu-116677 Taeniopygia guttata 70.49 0.00e+00 5299.00
IUUC-Tru-118037 Takifugu rubripes 45.64 0.00e+00 1944.00
IUUC-Tsy-118932 Tarsius syrichta 84.56 0.00e+00 5053.00
IUUC-Tni-119970 Tetraodon nigroviridis 47.08 0.00e+00 1395.00
IUUC-Ttr-129051 Tursiops truncatus 80.33 0.00e+00 6375.00
IUUC-Vpa-130236 Vicugna pacos 77.51 0.00e+00 1799.00
Created Date 25-Jun-2017

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