iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mpu-066366

Ensembl Protein ID

ENSMPUP00000009152.1

UniProt Accession

M3YCU5; M3YCU5_MUSPF

Genbank Protein ID

ENSMPUP00000009152

Protein Name

Histone-lysine N-methyltransferase

Genbank Nucleotide ID

AEYP01064843

Gene Name

KMT2C

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMPUG00000009228.1	ENSMPUT00000009305.1	ENSMPUP00000009152.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	1.10e-31	108.8	691	741

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedek.slveCekCrewfHpaClklsveeelpnsekwiCpkCr 52
           ++C vCg+ g++ +  l+ C++C +++Hp C+++++ + + ++  w C +C+
   Q: 691  DMCVVCGSFGQGAEgRLLACSQCGQCYHPYCVSIKITKVVLSK-GWRCLECT 741
           79*********9999********************66666555.5******6 PP

Organism

Mustela putorius furo

Protein Sequence
(Fasta)

MEELSLVNVD KAVVSGSTER CAFCKHLGAT IKCCEEKCTQ TYHYPCAAGA GTFQDFRNFF 60
LLCPEHIDQA PERSKEDANC AVCDSPGDLL DQFFCTTCGQ HYHGMCLDIA VTPLKRAGWQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGGGC TGGAGACGAC AGAAACGGAA AATACTGTGG AAGCAGGTAT CAACTTCACA 60
GACTTTTTAA AAAAATGCAC ATCATAATTT GCACAACGAG CGTTTGGCTA TATGCTGAGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0489--Methyltransferase
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0949--S-adenosyl-L-methionine
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR034732--EPHD
IPR003889--FYrich_C
IPR003888--FYrich_N
IPR009071--HMG_box_dom
IPR003616--Post-SET_dom
IPR001214--SET_dom
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51805--EPHD
PS51543--FYRC
PS51542--FYRN
PS50868--POST_SET
PS50280--SET
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
PS50089--ZF_RING_2

Pfam

PF05965--FYRC
PF05964--FYRN
PF00628--PHD
PF00856--SET

SMART

SM00542--FYRC
SM00541--FYRN
SM00398--HMG
SM00249--PHD
SM00508--PostSET
SM00317--SET

Gene Ontology

GO:0044666--C:MLL3/4 complex
GO:0042800--F:histone methyltransferase activity (H3-K4 specific)
GO:0003723--F:RNA binding
GO:0008270--F:zinc ion binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002314	Ailuropoda melanoleuca	92.33	0.00e+00	7393.00
IUUC-Apl-003311	Anas platyrhynchos	71.35	0.00e+00	5442.00
IUUC-Aca-004705	Anolis carolinensis	65.84	0.00e+00	5022.00
IUUC-Bta-012322	Bos taurus	83.59	0.00e+00	6623.00
IUUC-Cel-018354	Caenorhabditis elegans	35.67	1.00e-64	243.00
IUUC-Cja-019983	Callithrix jacchus	85.00	0.00e+00	6893.00
IUUC-Cfa-020903	Canis familiaris	90.49	0.00e+00	7411.00
IUUC-Cpo-021732	Cavia porcellus	80.56	0.00e+00	6443.00
IUUC-Csa-023083	Chlorocebus sabaeus	82.60	0.00e+00	5043.00
IUUC-Cho-024469	Choloepus hoffmanni	81.07	0.00e+00	2292.00
IUUC-Dre-028110	Danio rerio	63.52	0.00e+00	1231.00
IUUC-Dor-030569	Dipodomys ordii	78.98	0.00e+00	4364.00
IUUC-Dme-031590	Drosophila melanogaster	32.99	1.00e-67	252.00
IUUC-Eca-033945	Equus caballus	86.66	0.00e+00	4964.00
IUUC-Fca-035922	Felis catus	88.76	0.00e+00	6993.00
IUUC-Gac-041896	Gasterosteus aculeatus	46.37	0.00e+00	1756.00
IUUC-Ggo-044812	Gorilla gorilla	82.98	0.00e+00	6704.00
IUUC-Hsa-046595	Homo sapiens	85.23	0.00e+00	6870.00
IUUC-Itr-048303	Ictidomys tridecemlineatus	82.94	0.00e+00	6534.00
IUUC-Lch-050086	Latimeria chalumnae	57.45	0.00e+00	2479.00
IUUC-Loc-052891	Lepisosteus oculatus	52.52	0.00e+00	2085.00
IUUC-Laf-054348	Loxodonta africana	82.68	0.00e+00	3121.00
IUUC-Mcc-054868	Macaca mulatta	85.62	0.00e+00	6854.00
IUUC-Meu-056322	Macropus eugenii	64.93	0.00e+00	1102.00
IUUC-Mga-059541	Meleagris gallopavo	70.98	0.00e+00	5304.00
IUUC-Mmr-061092	Microcebus murinus	82.24	0.00e+00	5030.00
IUUC-Mdo-062610	Monodelphis domestica	73.81	0.00e+00	1789.00
IUUC-Mmu-063666	Mus musculus	81.22	0.00e+00	6416.00
IUUC-Mlu-068201	Myotis lucifugus	83.89	0.00e+00	4034.00
IUUC-Nle-069232	Nomascus leucogenys	82.33	0.00e+00	5029.00
IUUC-Opr-070625	Ochotona princeps	76.41	0.00e+00	1026.00
IUUC-Oan-072945	Ornithorhynchus anatinus	70.19	0.00e+00	3886.00
IUUC-Ocu-074920	Oryctolagus cuniculus	79.31	0.00e+00	4818.00
IUUC-Ola-086436	Oryzias latipes	46.54	0.00e+00	1749.00
IUUC-Oga-088637	Otolemur garnettii	80.20	0.00e+00	4232.00
IUUC-Oar-089363	Ovis aries	82.21	0.00e+00	6428.00
IUUC-Ptr-091527	Pan troglodytes	85.11	0.00e+00	6919.00
IUUC-Pan-092102	Papio anubis	83.74	0.00e+00	6691.00
IUUC-Pma-094252	Petromyzon marinus	40.44	0.00e+00	658.00
IUUC-Pfo-096288	Poecilia formosa	48.21	0.00e+00	1515.00
IUUC-Pab-098241	Pongo abelii	85.23	0.00e+00	4647.00
IUUC-Pca-100103	Procavia capensis	92.11	0.00e+00	1403.00
IUUC-Pva-102238	Pteropus vampyrus	79.58	0.00e+00	2724.00
IUUC-Sha-106550	Sarcophilus harrisii	70.22	0.00e+00	4070.00
IUUC-Sar-113183	Sorex araneus	90.99	4.00e-156	547.00
IUUC-Tgu-116677	Taeniopygia guttata	70.27	0.00e+00	5308.00
IUUC-Tru-118037	Takifugu rubripes	47.32	0.00e+00	1459.00
IUUC-Tsy-118932	Tarsius syrichta	84.96	0.00e+00	5170.00
IUUC-Tni-119970	Tetraodon nigroviridis	48.02	0.00e+00	1421.00
IUUC-Ttr-129051	Tursiops truncatus	83.76	0.00e+00	6402.00
IUUC-Vpa-130236	Vicugna pacos	84.40	0.00e+00	2026.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence