iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pfo-097262

Ensembl Protein ID

ENSPFOP00000009106.1

UniProt Accession

A0A087XTK3; A0A087XTK3_POEFO

Genbank Protein ID

ENSPFOP00000009106

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AYCK01023943

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPFOG00000007797.1	ENSPFOT00000009118.1	ENSPFOP00000009106.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.70e-17	62.7	3486	3518
E3 activity/HECT	2.50e-88	297.2	4581	4915

Active Site

Position(s)	Description	Evidence
4884	Glycyl thioester intermediate	{ECO:0000256\|PROSITE-ProRule:PRU00104}

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           H+++v  + + s  +ll+++++Dgt++vW++++
   Q: 3486 HQSRVITCGWcSKkGLLATSGGDGTVRVWNVTK 3518
           899988889*9778****************975 PP

E3 activity/HECT

   S: 6    kkrle.vefvgEegldlgGvtreflallskelqnpdlglflysendketlqpnpdsglknp.....ehlklFeflGrllgkalqdgr 86
            +r++ v++vgE + d+gGv+ ++++++++el++  + l+  s+n ++++ +n+d++l np     eh+  F+flG+l+g+a+++++
   Q: 4581 PSRAWkVKLVGEGADDAGGVFDDTITEMCQELETGVVDLLIPSPNATAEVGYNRDRFLFNPsacldEHMIQFKFLGILMGVAVRTKK 4667
           466666********************************************************************************* PP
   S: 87   lldlplsksfyklllgkklsledleevdpelykslkeikenaesdieelgldltfsvseeilgetkeee..LkpgGenipVtneNke 171
           +ldl+l++ ++k+l+  +l+ledleevd  ++++lk+i++ ++s i+e +++ ++  ++ + ++++ ++  ++pgG +ip   +N++
   Q: 4668 PLDLHLAPLVWKQLCCIPLQLEDLEEVDLLYVQTLKSILHIEDSGITEDSFHEMIPLDSFVGQSADGKMvpIIPGGGSIPLSFSNRK 4754
           *******************************************************9999887777766666**************** PP
   S: 172  eYvklvveyrlkegikeqveafreGfneviplellslFteeelellicGeeeidvedlkketkykggytedspaiqwFwevleefss 258
           eYv++ veyrl+e i++qv+a+reG+++++p  llsl+t+++le+++cG++ei  e lkk  +y++ + e++  +qwFw++leefs+
   Q: 4755 EYVERAVEYRLHE-IDRQVAAVREGMSWIVPVPLLSLLTARQLEQMVCGMPEICCEVLKKVVRYRE-VDEQHALVQWFWQTLEEFSN 4839
           *************.**************************************************88.******************** PP
   S: 259  eerkafLqFvTgssrlPlgGfaelkprlfvirk.dasddrlPssnTCfnyLkLPeYsskeilkekLlyAieetkgFel 335
           +er  f++Fv+g+srlP+ + a+++ ++f+i k d+  d+lP+s+TCf++L+LP+Yss+ ++ e+L+yAi++++++++
   Q: 4840 DERVLFMRFVSGRSRLPA-NTADIS-QRFQIMKvDRPYDSLPTSQTCFFQLRLPPYSSQAVMAERLRYAINNCRSIDM 4915
           *****************6.899999.679999956666***********************************99987 PP

Organism

Poecilia formosa

Protein Sequence
(Fasta)

MALMIPPVKL KWLEHLNSSW ITEDSESIAT RNGVSALYAK LLANKEAVLL PQQVLCLKGP 60
QLPDFERESL SSDEQEHYLD ALLGSQLALA KMVCSDSPFA AALRKRVLVL QRVFYALSNK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCGCTGA TGATCCCCCC GGTGAAACTC AAATGGCTGG AGCACCTGAA CAGCTCGTGG 60
ATCACGGAGG ACAGCGAGTC CATCGCCACG CGGAACGGCG TGTCGGCGCT CTACGCCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat

Interpro

IPR011989--ARM-like
IPR001870--B30.2/SPRY
IPR013320--ConA-like_dom
IPR000569--HECT_dom
IPR009091--RCC1/BLIP-II
IPR000408--Reg_chr_condens
IPR003877--SPRY_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50188--B302_SPRY
PS50237--HECT
PS00626--RCC1_2
PS50012--RCC1_3
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00632--HECT
PF00415--RCC1
PF00622--SPRY
PF00400--WD40

PRINTS

PR00633--RCCNDNSATION

SMART

SM00119--HECTc
SM00449--SPRY
SM00320--WD40

Gene Ontology

GO:0004842--F:ubiquitin-protein transferase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001830	Ailuropoda melanoleuca	80.77	0.00e+00	7220.00
IUUC-Apl-003461	Anas platyrhynchos	80.87	0.00e+00	7249.00
IUUC-Aca-004452	Anolis carolinensis	78.31	0.00e+00	6688.00
IUUC-Bta-013213	Bos taurus	80.89	0.00e+00	7219.00
IUUC-Bra-017584	Brassica rapa	34.15	5.00e-50	193.00
IUUC-Cja-019298	Callithrix jacchus	80.75	0.00e+00	7208.00
IUUC-Cfa-021213	Canis familiaris	80.72	0.00e+00	7289.00
IUUC-Cpo-021674	Cavia porcellus	79.55	0.00e+00	4960.00
IUUC-Csa-023341	Chlorocebus sabaeus	80.23	0.00e+00	7168.00
IUUC-Cho-024567	Choloepus hoffmanni	73.28	0.00e+00	1371.00
IUUC-Dre-028289	Danio rerio	81.19	0.00e+00	7263.00
IUUC-Dno-029988	Dasypus novemcinctus	80.25	0.00e+00	7175.00
IUUC-Dor-030636	Dipodomys ordii	82.79	0.00e+00	1891.00
IUUC-Ete-032598	Echinops telfairi	81.15	0.00e+00	1313.00
IUUC-Eca-033754	Equus caballus	80.67	0.00e+00	7220.00
IUUC-Eeu-034702	Erinaceus europaeus	71.03	0.00e+00	1179.00
IUUC-Fca-035900	Felis catus	80.80	0.00e+00	7243.00
IUUC-Fal-037034	Ficedula albicollis	78.57	0.00e+00	6177.00
IUUC-Gmo-039260	Gadus morhua	82.78	0.00e+00	1395.00
IUUC-Gga-040321	Gallus gallus	80.56	0.00e+00	7285.00
IUUC-Gma-043808	Glycine max	32.99	3.00e-44	174.00
IUUC-Ggo-045134	Gorilla gorilla	74.11	0.00e+00	3681.00
IUUC-Hsa-046516	Homo sapiens	80.44	0.00e+00	7184.00
IUUC-Itr-048914	Ictidomys tridecemlineatus	85.43	0.00e+00	2257.00
IUUC-Lch-049903	Latimeria chalumnae	81.53	0.00e+00	7309.00
IUUC-Lpe-051165	Leersia perrieri	35.15	8.00e-52	197.00
IUUC-Loc-052149	Lepisosteus oculatus	83.07	0.00e+00	5223.00
IUUC-Laf-053426	Loxodonta africana	80.76	0.00e+00	7281.00
IUUC-Mcc-055826	Macaca mulatta	80.55	0.00e+00	7218.00
IUUC-Meu-056521	Macropus eugenii	67.83	0.00e+00	1786.00
IUUC-Mga-059567	Meleagris gallopavo	86.81	0.00e+00	1888.00
IUUC-Mmr-061512	Microcebus murinus	80.19	0.00e+00	7131.00
IUUC-Mdo-062177	Monodelphis domestica	78.26	0.00e+00	5075.00
IUUC-Mmu-064373	Mus musculus	80.63	0.00e+00	7221.00
IUUC-Mpu-066148	Mustela putorius furo	80.61	0.00e+00	7220.00
IUUC-Mlu-067680	Myotis lucifugus	80.35	0.00e+00	7156.00
IUUC-Nle-069633	Nomascus leucogenys	80.29	0.00e+00	7135.00
IUUC-Opr-070609	Ochotona princeps	83.17	0.00e+00	1198.00
IUUC-Ont-071249	Oreochromis niloticus	89.55	0.00e+00	8233.00
IUUC-Oan-073157	Ornithorhynchus anatinus	80.16	0.00e+00	7141.00
IUUC-Ocu-074841	Oryctolagus cuniculus	80.55	0.00e+00	7249.00
IUUC-Oba-075262	Oryza barthii	34.83	8.00e-51	194.00
IUUC-Obr-076115	Oryza brachyantha	35.44	8.00e-50	191.00
IUUC-Ogl-077586	Oryza glaberrima	34.83	8.00e-51	194.00
IUUC-Ogu-078796	Oryza glumaepatula	34.58	3.00e-50	192.00
IUUC-Oin-079298	Oryza indica	34.58	3.00e-50	192.00
IUUC-Olo-080768	Oryza longistaminata	36.60	3.00e-55	209.00
IUUC-Ome-081908	Oryza meridionalis	34.26	4.00e-49	189.00
IUUC-Oni-082049	Oryza nivara	34.58	3.00e-50	192.00
IUUC-Opu-083608	Oryza punctata	34.83	3.00e-51	196.00
IUUC-Oru-084712	Oryza rufipogon	34.58	3.00e-50	192.00
IUUC-Osa-086078	Oryza sativa	34.58	3.00e-50	192.00
IUUC-Ola-086889	Oryzias latipes	87.60	0.00e+00	7908.00
IUUC-Oga-088459	Otolemur garnettii	79.80	0.00e+00	7146.00
IUUC-Oar-089888	Ovis aries	80.89	0.00e+00	7195.00
IUUC-Ptr-091114	Pan troglodytes	80.55	0.00e+00	7198.00
IUUC-Pan-092442	Papio anubis	80.43	0.00e+00	7193.00
IUUC-Psi-093833	Pelodiscus sinensis	79.84	0.00e+00	4805.00
IUUC-Pma-094275	Petromyzon marinus	77.23	0.00e+00	1680.00
IUUC-Ppa-095790	Physcomitrella patens	36.86	9.00e-55	207.00
IUUC-Pab-097760	Pongo abelii	79.50	0.00e+00	4078.00
IUUC-Pca-100465	Procavia capensis	80.00	0.00e+00	3830.00
IUUC-Ppe-101345	Prunus persica	33.33	8.00e-51	196.00
IUUC-Pva-102950	Pteropus vampyrus	80.24	0.00e+00	3385.00
IUUC-Rno-104892	Rattus norvegicus	80.49	0.00e+00	7177.00
IUUC-Sha-106633	Sarcophilus harrisii	79.65	0.00e+00	7067.00
IUUC-Smo-108827	Selaginella moellendorffii	35.66	1.00e-52	202.00
IUUC-Sit-110415	Setaria italica	37.97	5.00e-55	208.00
IUUC-Sly-111155	Solanum lycopersicum	35.97	5.00e-54	206.00
IUUC-Sar-113251	Sorex araneus	71.31	0.00e+00	2013.00
IUUC-Ssc-116391	Sus scrofa	80.75	0.00e+00	7245.00
IUUC-Tgu-116554	Taeniopygia guttata	80.51	0.00e+00	7229.00
IUUC-Tru-118695	Takifugu rubripes	88.31	0.00e+00	8080.00
IUUC-Tsy-119647	Tarsius syrichta	71.66	0.00e+00	4335.00
IUUC-Tni-120707	Tetraodon nigroviridis	88.07	0.00e+00	8009.00
IUUC-Tbe-127346	Tupaia belangeri	76.63	0.00e+00	2228.00
IUUC-Ttr-128542	Tursiops truncatus	74.98	0.00e+00	4565.00
IUUC-Vpa-130611	Vicugna pacos	81.32	0.00e+00	3303.00
IUUC-Xtr-131933	Xenopus tropicalis	78.54	0.00e+00	6987.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence