iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106641

Ensembl Protein ID

ENSSHAP00000001884.1

UniProt Accession

G3VFD0; G3VFD0_SARHA

Genbank Protein ID

ENSSHAP00000001884

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01204510

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000001678.1	ENSSHAT00000001905.1	ENSSHAP00000001884.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.20e-17	61.3	410	466

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ i ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 410  RVRALYDYEGQEHDELSFKAGDELTKI-EDEDEQGWCKG-RLDNGQVGLYPANYVEAIQ 466
           799************************.9**********.59*************9885 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

IGNYKRTVKR IDDGHRLCND LMNCIHERAR IEKAYAQQLT EWAKRWKQLV EKGPQYGTVE 60
KAWNAVMSEA EKVSELHLEV KGSLMNEDFE KIKNWQKEAF HKQMMGGFKE TREAEDGFRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAAAATACAC ATAGAAGAAC TGCACATGTT TAACCTATAT CGAATGGTTG TCTAGGGGAG 60
GGAGGTAGAG GGGAAGAAGG GAGAAAAATT AGGAACATGG GGTTTTTCAA GAGTGAATGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome

KEGG

shr:100935156

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	90.77	0.00e+00	838.00
IUUC-Apl-003574	Anas platyrhynchos	88.87	0.00e+00	787.00
IUUC-Aca-004251	Anolis carolinensis	86.05	0.00e+00	764.00
IUUC-Ame-011756	Astyanax mexicanus	67.54	0.00e+00	662.00
IUUC-Bta-013193	Bos taurus	88.41	0.00e+00	787.00
IUUC-Cel-018168	Caenorhabditis elegans	31.38	1.00e-57	217.00
IUUC-Cja-018756	Callithrix jacchus	90.56	0.00e+00	787.00
IUUC-Cfa-020545	Canis familiaris	90.99	0.00e+00	841.00
IUUC-Cpo-022000	Cavia porcellus	87.12	0.00e+00	855.00
IUUC-Csa-024030	Chlorocebus sabaeus	89.21	0.00e+00	734.00
IUUC-Cin-025707	Ciona intestinalis	41.45	1.00e-100	360.00
IUUC-Csv-026244	Ciona savignyi	41.35	4.00e-54	204.00
IUUC-Dre-028104	Danio rerio	62.24	3.00e-162	564.00
IUUC-Dno-029429	Dasypus novemcinctus	89.65	0.00e+00	788.00
IUUC-Dor-030122	Dipodomys ordii	83.26	0.00e+00	753.00
IUUC-Dme-032120	Drosophila melanogaster	43.40	1.00e-104	373.00
IUUC-Eca-033367	Equus caballus	88.20	0.00e+00	808.00
IUUC-Eeu-034821	Erinaceus europaeus	71.67	0.00e+00	638.00
IUUC-Fca-036079	Felis catus	91.42	0.00e+00	842.00
IUUC-Fal-036682	Ficedula albicollis	88.44	0.00e+00	783.00
IUUC-Gmo-039681	Gadus morhua	63.62	8.00e-150	523.00
IUUC-Gga-040717	Gallus gallus	88.65	0.00e+00	786.00
IUUC-Gac-042262	Gasterosteus aculeatus	64.61	7.00e-167	579.00
IUUC-Ggo-044841	Gorilla gorilla	89.48	0.00e+00	778.00
IUUC-Hsa-046411	Homo sapiens	89.48	0.00e+00	777.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	89.70	0.00e+00	792.00
IUUC-Lch-050070	Latimeria chalumnae	67.80	2.00e-178	618.00
IUUC-Loc-051975	Lepisosteus oculatus	70.80	0.00e+00	698.00
IUUC-Laf-053839	Loxodonta africana	88.63	0.00e+00	821.00
IUUC-Mcc-055783	Macaca mulatta	89.48	0.00e+00	779.00
IUUC-Mga-060087	Meleagris gallopavo	82.87	0.00e+00	714.00
IUUC-Mmr-060827	Microcebus murinus	89.70	0.00e+00	825.00
IUUC-Mmu-064109	Mus musculus	89.48	0.00e+00	820.00
IUUC-Mpu-066591	Mustela putorius furo	91.85	0.00e+00	846.00
IUUC-Mlu-067826	Myotis lucifugus	91.20	0.00e+00	840.00
IUUC-Nle-069797	Nomascus leucogenys	89.91	0.00e+00	781.00
IUUC-Ont-072188	Oreochromis niloticus	62.39	6.00e-162	563.00
IUUC-Oan-073076	Ornithorhynchus anatinus	84.35	1.00e-159	555.00
IUUC-Ocu-074425	Oryctolagus cuniculus	89.48	0.00e+00	796.00
IUUC-Ola-087556	Oryzias latipes	64.84	2.00e-158	551.00
IUUC-Oga-089009	Otolemur garnettii	84.11	0.00e+00	771.00
IUUC-Oar-089806	Ovis aries	88.41	0.00e+00	787.00
IUUC-Ptr-091111	Pan troglodytes	89.06	0.00e+00	773.00
IUUC-Pan-091749	Papio anubis	89.27	0.00e+00	776.00
IUUC-Psi-093704	Pelodiscus sinensis	89.29	0.00e+00	805.00
IUUC-Pfo-096680	Poecilia formosa	63.45	1.00e-163	569.00
IUUC-Pva-102649	Pteropus vampyrus	88.84	0.00e+00	796.00
IUUC-Rno-105431	Rattus norvegicus	89.32	0.00e+00	848.00
IUUC-Sar-113461	Sorex araneus	78.54	0.00e+00	704.00
IUUC-Ssc-115349	Sus scrofa	90.32	0.00e+00	799.00
IUUC-Tgu-116876	Taeniopygia guttata	88.44	0.00e+00	784.00
IUUC-Tru-118306	Takifugu rubripes	67.92	1.00e-171	595.00
IUUC-Tsy-118901	Tarsius syrichta	81.19	2.00e-152	531.00
IUUC-Tni-120120	Tetraodon nigroviridis	67.09	2.00e-172	598.00
IUUC-Xtr-132925	Xenopus tropicalis	81.58	0.00e+00	758.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence