iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Ggo-045263

Ensembl Protein ID

ENSGGOP00000022651.1

UniProt Accession

G3S3K1; G3S3K1_GORGO

Protein Name

Uncharacterized protein

Gene Name

MAP3K5

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSGGOG00000015494.2	ENSGGOT00000034704.1	ENSGGOP00000022651.1
ENSGGOG00000015494.2	ENSGGOT00000015554.2	ENSGGOP00000015122.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
ULD/UDP/UBQ/UBQ_Other	97.90	0.00e+00	2519.00	IUUC-Hsa-046906

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Gorilla gorilla

Protein Sequence
(Fasta)

MSTEADEGIT FSVPPFAPSG FCTIPEGGIC RRGGAAAVGE GEEHQLPPPP PGSFWNVESA 60
AAPGIGCPAA TSSSSATRGR GSSVGGGSRR TTVAYVINEA SQGQLVVAES EALQSLREAC 120

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Nucleotide Sequence
(Fasta)

GTACTCTAAA CTCTGCAGAG GGCGAGCGGC GCGGCCACGG AGGCGCCGAG GAGGAGCGAG 60
CCGCCGCCGG GCAGCGGCGT GCCCTCGGGG GAGAGGGCGC CGGAGAGGAG GCGGCGGCGC 120

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Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0175--Coiled coil
KW-0181--Complete proteome
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-1185--Reference proteome
KW-0808--Transferase

Interpro

IPR025136--DUF4071
IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR013761--SAM/pointed

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM

Pfam

PF13281--DUF4071
PF00069--Pkinase

Gene Ontology

GO:1990604--C:IRE1-TRAF2-ASK1 complex
GO:1902911--C:protein kinase complex
GO:0005524--F:ATP binding
GO:0000287--F:magnesium ion binding
GO:0004709--F:MAP kinase kinase kinase activity
GO:0000187--P:activation of MAPK activity
GO:0070301--P:cellular response to hydrogen peroxide
GO:1902170--P:cellular response to reactive nitrogen species
GO:0070059--P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:0008631--P:intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0007254--P:JNK cascade
GO:0038066--P:p38MAPK cascade
GO:0043280--P:positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043507--P:positive regulation of JUN kinase activity
GO:0045663--P:positive regulation of myoblast differentiation
GO:1901216--P:positive regulation of neuron death
GO:0097300--P:programmed necrotic cell death

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002318	Ailuropoda melanoleuca	95.03	0.00e+00	2278.00
IUUC-Apl-003713	Anas platyrhynchos	87.05	0.00e+00	1997.00
IUUC-Aca-005331	Anolis carolinensis	85.62	0.00e+00	2010.00
IUUC-Ame-011158	Astyanax mexicanus	72.20	0.00e+00	1778.00
IUUC-Bta-012770	Bos taurus	93.32	0.00e+00	2381.00
IUUC-Cja-019656	Callithrix jacchus	96.52	0.00e+00	2484.00
IUUC-Cfa-020488	Canis familiaris	94.19	0.00e+00	2377.00
IUUC-Cpo-022516	Cavia porcellus	93.01	0.00e+00	2255.00
IUUC-Csa-023104	Chlorocebus sabaeus	97.22	0.00e+00	2275.00
IUUC-Cho-024379	Choloepus hoffmanni	86.45	0.00e+00	1156.00
IUUC-Dre-028836	Danio rerio	73.32	0.00e+00	1803.00
IUUC-Dno-029842	Dasypus novemcinctus	92.21	0.00e+00	2125.00
IUUC-Dor-030990	Dipodomys ordii	93.07	0.00e+00	1862.00
IUUC-Ete-032693	Echinops telfairi	85.40	0.00e+00	1371.00
IUUC-Eca-033337	Equus caballus	93.67	0.00e+00	2241.00
IUUC-Eeu-034602	Erinaceus europaeus	80.04	0.00e+00	2051.00
IUUC-Fca-035954	Felis catus	94.03	0.00e+00	1858.00
IUUC-Fal-037358	Ficedula albicollis	86.57	0.00e+00	2027.00
IUUC-Gmo-038836	Gadus morhua	76.31	0.00e+00	1686.00
IUUC-Gga-040443	Gallus gallus	84.81	0.00e+00	2159.00
IUUC-Gac-041634	Gasterosteus aculeatus	73.18	0.00e+00	1858.00
IUUC-Hsa-046906	Homo sapiens	97.82	0.00e+00	2519.00
IUUC-Itr-048449	Ictidomys tridecemlineatus	92.00	0.00e+00	1036.00
IUUC-Lch-050213	Latimeria chalumnae	76.56	0.00e+00	1727.00
IUUC-Loc-051829	Lepisosteus oculatus	70.14	0.00e+00	1798.00
IUUC-Laf-053538	Loxodonta africana	93.68	0.00e+00	2421.00
IUUC-Mcc-054776	Macaca mulatta	97.24	0.00e+00	2537.00
IUUC-Mga-059636	Meleagris gallopavo	86.54	0.00e+00	2056.00
IUUC-Mmr-061323	Microcebus murinus	95.29	0.00e+00	2409.00
IUUC-Mdo-062146	Monodelphis domestica	89.38	0.00e+00	2254.00
IUUC-Mmu-064022	Mus musculus	92.12	0.00e+00	2349.00
IUUC-Mpu-066531	Mustela putorius furo	91.22	0.00e+00	2389.00
IUUC-Mlu-068181	Myotis lucifugus	89.18	0.00e+00	2322.00
IUUC-Nle-069758	Nomascus leucogenys	97.38	0.00e+00	2278.00
IUUC-Opr-070531	Ochotona princeps	85.19	0.00e+00	1391.00
IUUC-Ont-072014	Oreochromis niloticus	75.39	0.00e+00	1831.00
IUUC-Oan-073169	Ornithorhynchus anatinus	91.39	0.00e+00	2169.00
IUUC-Ocu-074050	Oryctolagus cuniculus	90.80	0.00e+00	2098.00
IUUC-Ola-086941	Oryzias latipes	77.66	0.00e+00	1474.00
IUUC-Oga-088796	Otolemur garnettii	94.56	0.00e+00	2405.00
IUUC-Oar-090445	Ovis aries	94.78	0.00e+00	2220.00
IUUC-Ptr-090846	Pan troglodytes	97.53	0.00e+00	2539.00
IUUC-Pan-091986	Papio anubis	97.31	0.00e+00	2539.00
IUUC-Psi-093805	Pelodiscus sinensis	87.00	0.00e+00	2158.00
IUUC-Pfo-097301	Poecilia formosa	71.97	0.00e+00	1850.00
IUUC-Pab-097662	Pongo abelii	97.45	0.00e+00	2434.00
IUUC-Pca-100755	Procavia capensis	95.17	0.00e+00	726.00
IUUC-Pva-102280	Pteropus vampyrus	85.11	0.00e+00	2190.00
IUUC-Rno-105547	Rattus norvegicus	90.89	0.00e+00	2333.00
IUUC-Sha-106859	Sarcophilus harrisii	88.84	0.00e+00	2204.00
IUUC-Sar-113714	Sorex araneus	90.73	0.00e+00	1256.00
IUUC-Tgu-117116	Taeniopygia guttata	85.34	0.00e+00	2097.00
IUUC-Tru-118088	Takifugu rubripes	74.61	0.00e+00	1866.00
IUUC-Tsy-119616	Tarsius syrichta	91.56	0.00e+00	2011.00
IUUC-Tni-120284	Tetraodon nigroviridis	73.62	0.00e+00	1824.00
IUUC-Tbe-127900	Tupaia belangeri	89.87	0.00e+00	778.00
IUUC-Ttr-128294	Tursiops truncatus	83.97	0.00e+00	1294.00
IUUC-Vpa-130470	Vicugna pacos	87.24	0.00e+00	2057.00
IUUC-Xtr-132396	Xenopus tropicalis	73.65	0.00e+00	1900.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence